Dermatologists are often the first medical professionals to see patients with HIV infection, as skin diseases are common in acquired immunodeficiency syndrome. This book aims to help dermatologists recognize the cutaneous manifestations of HIV infection and AIDS, so that diagnosis can be made quickly and therapy begun as soon as possible. The book
Dermatopathology is a specialized branch of pathology in which there has been great progress as new techniques have become available to evaluate the pathology of the skin. Many of the advances in our knowledge and understanding of the skin and the diseases that affect it have been made by people with experience of both diagnostic pathology and clinical dermatology. With significant numbers of large textbooks available, there is a need to provide practical clinical information and concise criteria for pathologic diagnosis for pathologists and dermatologists looking for up-to-date diagnostic and management options.
For Secretary of State Henry Clay and the Adams administration, 1827 is a year of crisis. Turbulent relations with Latin America are marked by the seizure of American trading vessels off Montevideo. Border strife with Britain threatens in northern Maine, while American retaliation for the closing of the British West Indies to U.S. trade provokes warnings of war from the opposition in Congress. With the campaign for the next presidency in full swing, Clay is again forced to defend himself against Andrew Jackson's charges of "bribery and corruption." Opposition gains in the fall elections foreshadow Jackson's 1828 victory, but at year's end, the resilient Clay continues to hope. Publication of this book was assisted by a grant from the National Historical Publications and Records Commission.
The science of the virus and its effects and the clinical approaches to its treatment and transmission prevention are placed in the context of the history and epidemiology of the HIV-AIDS pandemic. Each organ system of the body is explored as to manifestations of the disease, treatment now and in the future, as well as what the disease has taught us about the immune response. The science of epidemiology, which is so important in allowing for tracking of the disease and potential limitation of transmission, is another aspect of AIDS explored in detail. The pandemic manifests differently in different parts of the world, and the relevance of the volume is enhanced by its international group of contributors. No other text provides the historical and epidemiological context of this disease along with an update of diagnosis and treatment. The underlying science and epidemiology of AIDS are not neglected, so the student or clinician who is treating patients with AIDS can gain a full understanding of HIV/AIDS in individual patients and in their communities.
In volume 5 of The Papers of Henry Clay, the second of the series to cover Clay's role as Secretary of State, problems arising from domestic political pressures become significant in the conduct of national affairs both at home and abroad. With the president absent from Washington one-third of the year, Clay's burden and his personal role in the conduct of office are evident. His health becomes precarious, he neglects to take action to forestall embarrassing ministerial faux pas in several areas, and he misjudges the gravity of British alienation—all of these handicaps to the future course of his administration here become manifest.
The ante bellum homes of Lexington and Fayette County, Kentucky, are both more numerous and more distinctive in design than those of many communities of similar age. Founded in 1775, Lexington by the turn of the century had become the chief cultural center north of New Orleans and west of the Alleghenies. During the eight decades between the Revolution and the Civil War, Fayette County was the focus of converging streams of immigration, and a phenomenal amount of building activity took place in Lexington and the surrounding area. Although local builders followed the trends of national architecture, they were not primarily concerned with "correctness," and developed a provincial style which was distinguished by originality and a high level of craftsmanship. In Ante Bellum Houses of the Bluegrass, Clay Lancaster seeks to define the indigenous character of Fayette County building, which he concludes is of unusually distinguished quality. A second aim is the presentation of authentic data as a guide for intelligent restoration of existing old buildings, many of which have been defaced by unnecessary changes and inappropriate additions. He traces the development of house building in this restricted area from the first crude log cabins, through frame, stone, and early brick residences, to the substantial homes built by wealthy landowners and merchants in the mid-nineteenth century. The text is supplemented by 200 line drawings which present the essential features of each building free from the later alterations and decay which would be recorded by the camera. These illustrations have been compiled on the basis of intensive research, from old photographs, maps, drawings, and other records. An album of halftone illustrations, many of which are reproductions of old photographs of buildings which have been altered or demolished, supplements these illustrations.
During the eight decades preceding the Civil War, Kentucky was the scene of tremendous building activity. Located in the western section of the original English colonies, midway between North and South, Kentucky saw the rise of an architecture that combined the traditions of nationally known designers, eager to achieve the refinements of their English mother culture, alongside the innovativeness and bold originality proper to the frontier. Tradition thus provided a tangible link with world architectural development, while innovation offered refreshing variations. The result was a distinctive regional architecture. In his newest look at Kentucky architecture, Clay Lancaster broadens his scope to include analyses of significant structures from throughout the commonwealth, illustrating the entire range of stylistic development. Like his acclaimed earlier book Antebellum Houses of the Bluegrass, the current volume provides historical background as well as drawings, photographs, and floor plans, showing both general features and details. Among the many Kentucky buildings discussed are examples by such well-known early American architects as Benjamin Henry Latrobe, Thomas Jefferson, James Dakin, Isaiah Rogers, Alexander J. Davis, and Francis Costigan, as well as the work of local master builders such as Matthew Kennedy, Micajah Burnett, Gideon Shryock, Thomas Lewinski, and John McMurtry. Also included are Kentucky buildings designed from nationally distributed architectural books and builders' guides. Lancaster gives special attention to the Geometric Style, which evolved further and produced more noteworthy monuments in Kentucky than anywhere else in America. Such buildings, in turn, bestowed a simplicity and straightforwardness on structures in later styles. As Lancaster shows, the architecture that resulted from Kentucky's fertile eclecticism constitutes a rich and rewarding architectural heritage. All lovers of fine architecture will treasure this handsome and informative book.
Dermatopathology is a specialized branch of pathology in which there has been great progress as new techniques have become available to evaluate the pathology of the skin. Many of the advances in our knowledge and understanding of the skin and the diseases that affect it have been made by people with experience of both diagnostic pathology and clinical dermatology. With significant numbers of large textbooks available, there is a need to provide practical clinical information and concise criteria for pathologic diagnosis for pathologists and dermatologists looking for up-to-date diagnostic and management options.
Cancer of the Skin, edited by Drs. Rigel, Robinson, Ross, Friedman, Cockerell, Lim, Stockfleth, and Kirkwood, is your complete, multimedia guide to early diagnosis and effective medical and surgical treatment of melanoma and other skin cancers. Thoroughly updated with 11 new chapters, this broad-based, comprehensive reference provides you with the latest information on clinical genetics and genomics of skin cancer, targeted therapy for melanoma, the Vitamin D debate concerning the risks and benefits of sun exposure, and other timely topics. A new, multi-disciplinary team of contributors and editors comprised of leading experts in this field offers truly diverse perspectives and worldwide best practices. - Broaden your understanding of all aspects of skin cancer—from the underlying biology to clinical manifestations of the disease to diagnosis, and medical and surgical treatment—with this easy-to-use, comprehensive, multimedia reference. - See conditions as they appear in practice with guidance from detailed full-color images and step-by-step procedural videos. - Stay current with the latest advancements and therapies! 11 new chapters cover clinical genetics and genomics of skin cancer, targeted therapy for melanoma, the Vitamin D debate concerning the risks and benefits of sun exposure, and other essential topics. - Get truly diverse perspectives and worldwide best practices from a new, multi-disciplinary team of contributors and editors comprised of the world's leading experts Access the complete text online—including image bank and video library—at www.expertconsult.com
The science of the virus and its effects and the clinical approaches to its treatment and transmission prevention are placed in the context of the history and epidemiology of the HIV-AIDS pandemic. Each organ system of the body is explored as to manifestations of the disease, treatment now and in the future, as well as what the disease has taught us about the immune response. The science of epidemiology, which is so important in allowing for tracking of the disease and potential limitation of transmission, is another aspect of AIDS explored in detail. The pandemic manifests differently in different parts of the world, and the relevance of the volume is enhanced by its international group of contributors. No other text provides the historical and epidemiological context of this disease along with an update of diagnosis and treatment. The underlying science and epidemiology of AIDS are not neglected, so the student or clinician who is treating patients with AIDS can gain a full understanding of HIV/AIDS in individual patients and in their communities.
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