Christopher T. Walsh's Books

The Chemical Biology of Carbon

By: Christopher T. Walsh

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The Chemical Biology of Carbon

By: Christopher T. Walsh

The Chemical Biology of Carbon examines chemical biology open to carbon-containing natural metabolites that allow both retrospective and predictive behaviours of both biosynthetic and degradative metabolism in primary and secondary pathways ideal for medicinal chemists, chemical biologists and postgraduate students.

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Page Count

587

Publisher

Royal Society of Chemistry

Published Date

ISBN 10

1839168021

ISBN 13

9781839168024

The Chemical Biology of Nitrogen

By: Christopher T Walsh

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The Chemical Biology of Nitrogen

By: Christopher T Walsh

From DNA and RNA to proteins and vitamins the role of nitrogen is central in organismal metabolism. The Chemical Biology of Nitrogen comprehensively examines how the chemistry available to both inorganic and organic nitrogen compounds both enable and conditions the vast array of nitrogen biologies. This book provides a chemocentric approach to both the inorganic and organic chemical biology of nitrogen. Following an introduction to nitrogen trivalency the book progresses through the logic of inorganic nitrogen metabolism and organic nitrogen metabolites to nitrogen proteomics with an integrative approach to understanding the role of nitrogen in its many biologic roles. Authored by a renowned scientist and educator, this book is ideal for researchers in chemical biology and nitrogen metabolism and will be of particular interest to advanced students and postgraduates in biochemistry and chemical biology.

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Page Count

417

Publisher

Royal Society of Chemistry

Published Date

ISBN 10

1839164344

ISBN 13

9781839164347

The Chemical Biology of Phosphorus

By: Christopher T. Walsh

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The Chemical Biology of Phosphorus

By: Christopher T. Walsh

Alexander Todd, the 1957 Nobel laureate in chemistry is credited with the statement: "where there is life, there is phosphorus". Phosphorus chemical biology underlies most of life's reactions and processes, from the covalent bonds that hold RNA and DNA together, to the making and spending 75 kg of ATP every day, required to run almost all metabolic and mechanical events in cells. Authored by a renowned biochemist, The Chemical Biology of Phosphorus provides an in-depth, unifying chemical approach to the logic and reactivity of inorganic phosphate and its three major derivatives (anhydrides, mono- and diesters) throughout biology to examine why life depends on phosphorus. Covering the breadth of phosphorus chemistry in biology, this book is ideal for biochemistry students, postgraduates and researchers interested in the chemical logic of phosphate metabolites, energy generation, biopolymer accumulation and phosphoproteomics.

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Page Count

567

Publisher

Royal Society of Chemistry

Published Date

ISBN 10

1839162023

ISBN 13

9781839162022

The Chemical Biology of Sulfur

By: Christopher T Walsh

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The Chemical Biology of Sulfur

By: Christopher T Walsh

This volume aims to provide an in-depth view of the complete biochemistry of sulfur with an emphasis on aspects not covered elsewhere. Given its role in the formation of proteins and presence in the amino acids methionine and cysteine, sulfur is essential to life. Current literature on the biochemistry of sulfur is vast and widely dispersed, as such this volume is intended as a single-source for everything concerning sulfur biochemistry from metabolic roles of inorganic sulfur, to thiol and thioether chemical biology, to the university of cysteine chemistry in proteomes. Authored by a renowned biochemist and experienced writer and educator, this book is ideal for students and researchers in biochemistry, biology and the life sciences with an interest in sulfur and its role in life.

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Page Count

430

Publisher

Royal Society of Chemistry

Published Date

ISBN 10

1839161442

ISBN 13

9781839161445

Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery (2)

By: Christopher T Walsh,Yi Tang

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Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery (2)

By: Christopher T Walsh,Yi Tang

This second edition integrates many new findings into the underlying enzymatic mechanisms and the catalytic machinery for building the varied and complex end product metabolites. This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists.

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Royal Society of Chemistry

Published Date

ISBN 10

1839165642

ISBN 13

9781839165641

The Chemical Biology of Human Vitamins

By: Christopher Walsh,Yi Tang

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The Chemical Biology of Human Vitamins

By: Christopher Walsh,Yi Tang

This textbook provides a thorough chemocentric view on the key small molecules of life, the human vitamins and their active coenzyme forms.

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Page Count

462

Publisher

Royal Society of Chemistry

Published Date

ISBN 10

1788014642

ISBN 13

9781788014649

Natural Product Biosynthesis

Chemical Logic and Enzymatic Machinery

By: Christopher T Walsh,Yi Tang

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Natural Product Biosynthesis

Chemical Logic and Enzymatic Machinery

By: Christopher T Walsh,Yi Tang

Authored by leading experts in the enzymology of natural product biosynthesis, this completely revised and updated edition provides a description of the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era. Although some 500 000 – 600 000 natural products have been isolated and characterized over the past two centuries, there may be a 10-fold greater inventory awaiting immediate exploration based on biosynthetic gene cluster predictions. The approach of this book is to codify the chemical logic that underlies each natural product structural class as they are assembled from building blocks of primary metabolism. This second edition integrates many new findings into the sets of principles of the first edition that parsed categories of natural product chemistries into the underlying enzymatic mechanisms and the catalytic machinery for building the varied and complex end product metabolites. New chapters include evaluation of a core set of thermodynamically activated but kinetically stable metabolites that power both primary and secondary metabolic pathways. Also, after decades of uncertainty about the existence of various pericyclase classes, a series of genome mining, heterologous expression, and enzymatic activity characterization have validated a plethora of pericyclases over the past decade. The several types of pericyclases are involved in biosynthetic complexity generation of almost every major category of natural products. This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists. It will also be valuable to bioinformatic and computational biologists, pharmacognocists and chemical ecologists, and bioengineers and synthetic biologists.

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Page Count

1133

Publisher

Royal Society of Chemistry

Published Date

ISBN 10

1839168013

ISBN 13

9781839168017

Posttranslational Modification of Proteins

Expanding Nature's Inventory

By: Christopher Walsh

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Posttranslational Modification of Proteins

Expanding Nature's Inventory

By: Christopher Walsh

Covering the major classes of posttranslational modifications, Posttranslational Modification of Proteins is the first comprehensive treatment of this burgeoning area of proteome diversification.

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Page Count

524

Publisher

Roberts and Company Publishers

Published Date

ISBN 10

0974707732

ISBN 13

9780974707730

Book's by Christopher T. Walsh

The Chemical Biology of Carbon

The Chemical Biology of Carbon

The Chemical Biology of Nitrogen

The Chemical Biology of Nitrogen

The Chemical Biology of Phosphorus

The Chemical Biology of Phosphorus

The Chemical Biology of Sulfur

The Chemical Biology of Sulfur

Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery (2)

Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery (2)

The Chemical Biology of Human Vitamins

The Chemical Biology of Human Vitamins

Natural Product Biosynthesis

Natural Product Biosynthesis

Posttranslational Modification of Proteins

Posttranslational Modification of Proteins

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