This unique book examines the role of the brain's white matter in the organization of human mental function. In contrast to standard textbooks of behavioral neurology and neuropsychiatry that emphasize the cortical and subcortical gray matter in brain-behavior relationships, this text specifically considers the white matter as a vital contributor to cognition and emotion. Written from a clinical perspective, this book is founded on the study of patients with neurobehavioral syndromes resulting from disorders primarily affecting the brain's white matter. These syndromes include white matter dementia, focal neurobehavioral syndromes, and a variety of neuropsychiatric syndromes. In the first part of the book, fundamental aspects of myelinated systems are covered to introduce white matter as an important structural and functional component of the brain. In Part II, a thorough review of white matter disorders at all ages is provided, particularly regarding their impact on normal mentation. Finally, Part III synthesizes the collected information into a coherent summary that presents a behavioral neurology of white matter. Throughout the book a major emphasis is placed on distributed neural networks, in which connecting white matter tracts complement the operations of gray matter structures in the production of the human behavioral repertoire.
Breaking away from prevailing views of dementia that rely heavily on the role of the cerebral cortex, the new perspective put forth here highlights white matter-cognition relationships, presenting an expanded view of dementia and its neurobiological origins. Based on detailed patient observations, extensive clinical research and an exhaustive literature review, this book discusses the novel concept of white matter dementia, offering hope for better understanding and treatment of dementing illness. Covering topics such as white matter neurobiology, mild cognitive dysfunction and Alzheimer's disease, the author reconsiders brain-behavior relationships and expands the concept of dementia, discussing implications for diagnosis, treatment (medical, surgical, rehabilitative, and psychiatric) and therapeutic innovations aimed at prevention of white matter damage and restoration of myelin. This unique book is an absolute must-have for all medical specialists and consultants in neurology, neuropsychiatry, and neuropsychology involved with the growing challenge of dementia.
Thoroughly revised and updated to reflect key advances in behavioral neurology, Neurobehavioral Anatomy, Third Edition is a clinically based account of the neuroanatomy of human behavior centered on a consideration of behavioral dysfunction caused
Breaking away from prevailing views of dementia that rely heavily on the role of the cerebral cortex, the new perspective put forth here highlights white matter-cognition relationships, presenting an expanded view of dementia and its neurobiological origins. Based on detailed patient observations, extensive clinical research and an exhaustive literature review, this book discusses the novel concept of white matter dementia, offering hope for better understanding and treatment of dementing illness. Covering topics such as white matter neurobiology, mild cognitive dysfunction and Alzheimer's disease, the author reconsiders brain-behavior relationships and expands the concept of dementia, discussing implications for diagnosis, treatment (medical, surgical, rehabilitative, and psychiatric) and therapeutic innovations aimed at prevention of white matter damage and restoration of myelin. This unique book is an absolute must-have for all medical specialists and consultants in neurology, neuropsychiatry, and neuropsychology involved with the growing challenge of dementia.
This book considers the contribution of white matter to cognition and emotion. Every chapter has been rewritten and two new ones added. White matter dementia is updated, and the concept of mild cognitive dysfunction proposed. A unifying theme is connectivity within neural networks by which the human mind is organized.
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