With the mainstream's growing acceptance of worlds and storytelling spread among several different texts - e.g., films, television series, novels, and comics - this pioneering study employs a multidisciplinary approach combining transmediality, network theory, and narratology to analyze the narrative network of the Marvel Cinematic Universe. In this analysis, Christopher Hansen thoroughly examines storytelling techniques while providing a fresh theoretical framework to develop a structural model for interconnected narratives. He redefines our understanding of narrative dynamics in one of the most successful cinematic franchises of all time.
Known for its clear writing style, easy-to-navigate format, and authoritative coverage of tumor pathology, Dr. Christopher Fletcher's Diagnostic Histopathology of Tumors, 5th Edition, remains your go-to source for accurate, efficient evaluation and interpretation of histopathology specimens. This highly regarded reference provides superbly illustrated information on pathogenesis, diagnostic criteria, molecular/cytogenetic findings, and prognosis on the neoplastic diseases most likely to be encountered by general surgical pathologists, and helps you stay current with the latest diagnostic tumor markers to assist in daily sign-out. - Discusses the latest developments in immunohistochemistry, molecular genetics, targeted therapy/personalized medicine, and prognostic/predictive markers to assist in the diagnosis of the complete range of neoplastic entities. - Includes coverage of newly described variants and new histologic entities. - Covers all modern diagnostic techniques while retaining a strong emphasis on morphologic diagnosis, which remains the cornerstone of diagnosis for most lesions. - Features thousands of high-quality photographs, photomicrographs, and artwork throughout. - Incorporates the latest TNM and WHO classification and staging systems. - Contains diagnostic flow charts, correlations of gross appearances to microscopic findings, and differential diagnosis tables for better recognition and evaluation of similar-looking entities. - Shares the knowledge and expertise of internationally renowned experts in tumor pathology, including Dr. Christopher Fletcher, as well as numerous global authorities in the field.
Comprehensive and practice-oriented, the fully updated 3rd Edition of this easy-to-use text covers the full range of obstetric and gynecologic pathology, including information on treatment and patient management. Written largely by the pathology and clinical faculty at Harvard's Brigham and Women's Hospital, it covers the most up-to-date information available in the field, including molecular genetics and diagnostics. Drs. Christopher P. Crum and Marisa R. Nucci are joined by new editors Scott R. Granter, Brooke E. Howitt, Mana M. Parast, and Theonia K. Boyd, to provide complete, beautifully illustrated coverage of both neoplastic and non-neoplastic disorders of the female genital system, ideal for improving pathological diagnosis. - Provides distinct diagnostic/differential diagnostic criteria for any potential obstetric/gynecologic specimen encountered in practice. - Features more than 2,250 full-color images, key points at the end of each chapter, and an appendix with commonly used ICD-10 codes - Covers topics not often found in gynecologic pathology textbooks, such as vulvodynia, and diseases of the anus. - Approaches topics from a practice-oriented point of view, beginning with clinical presentation and progressing through histopathology, differential diagnosis, and treatment for each disorder. - Emphasizes new practice issues and their biologic basis including approaches to vulvar, cervical and endometrial precursors as well as the underpinnings of cervical, endometrial and ovarian cancer. - A comprehensive look at mesenchymal neoplasia, including not only lower genital tract and uterus but also the retroperitoneum. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
An updated volume in the best-selling Radiology RequisitesT series, Genitourinary Imaging, 3rd Edition presents the essentials of genitourinary radiology by describing the imaging techniques and diseases most commonly encountered in the field. Concise and practical, it familiarizes the reader with the pathology affecting the genitourinary system as well as an approach for detecting abnormalities. Extensive updates throughout reflect the significant changes in the way pathological processes in the genitourinary (GU) tract are imaged since publication of the last edition. Covering everything from basic principles through the latest diagnostic imaging techniques, equipment, and technology, it serves residents as a concise, easily readable text of GU imaging and serves as an update and reference for fellows and practicing radiologists. Synthesizes today's core knowledge in genitourinary radiology Practice-proven tips and excellent problem-solving discussions are accompanied by more than 450 high-quality images - nearly 400 all new - all demonstrating a full range of genitourinary radiologic approaches and imaging findings Numerous outlines, boxes, tables, "pearls," and suggested reading lists make reference easy. Numerous outlines, boxes, tables, "pearls," and suggested reading lists make reference easy. State-of-the-art coverage of MR urography, uterine artery embolization, CT for renal stone disease, and many other new areas in the field. The latest genitourinary imaging techniques with updated information on CT urography, MRI of the urinary tract, prostate MR, and much more. Newly edited and updated information throughout, including kidney tumor ablation and renal tumor imaging techniques and interpretation Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
An updated volume in the best-selling Radiology RequisitesTM series, Genitourinary Imaging, 3rd Edition presents the essentials of genitourinary radiology by describing the imaging techniques and diseases most commonly encountered in the field. Concise and practical, it familiarizes the reader with the pathology affecting the genitourinary system as well as an approach for detecting abnormalities. Extensive updates throughout reflect the significant changes in the way pathological processes in the genitourinary (GU) tract are imaged since publication of the last edition. Covering everything from basic principles through the latest diagnostic imaging techniques, equipment, and technology, it serves residents as a concise, easily readable text of GU imaging and serves as an update and reference for fellows and practicing radiologists. - Synthesizes today's core knowledge in genitourinary radiology - Practice-proven tips and excellent problem-solving discussions are accompanied by more than 450 high-quality images – nearly 400 all new — all demonstrating a full range of genitourinary radiologic approaches and imaging findings Numerous outlines, boxes, tables, "pearls," and suggested reading lists make reference easy. - Numerous outlines, boxes, tables, "pearls," and suggested reading lists make reference easy - State-of-the-art coverage of MR urography, uterine artery embolization, CT for renal stone disease, and many other new areas in the field. - The latest genitourinary imaging techniques with updated information on CT urography, MRI of the urinary tract, prostate MR, and much more. - Newly edited and updated information throughout, including kidney tumor ablation and renal tumor imaging techniques and interpretation - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
This book provides new knowledge, insights and experience about school-university partnerships. Drawing upon evidence from international research of the world’s most improved systems, and learning from a UK research council funded ‘knowledge exchange’ project, it reveals that when the profound differences between the practice worlds of schools and the theoretical worlds of university academics are embraced and cherished, rather than eschewed, school-university partnerships become exciting avenues of learning which connect, challenge and transform the thinking and practice of all those involved. Over its eight chapters, the book explores uncertainties, challenges and possibilities faced by those who seek to create, develop and sustain school-university partnerships that aspire to improve the practice and understanding of the leadership of teaching and learning in schools. It explicates and elucidates precepts, principles and practices for achieving such successful partnerships between higher education and school leaders, and contextualises these in terms of policy wide developments internationally. This book will appeal to school leaders internationally, leadership training organisations, and academics who lead postgraduate leadership and management programmes.
Authored by leading experts in the enzymology of natural product biosynthesis, this completely revised and updated edition provides a description of the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era. Although some 500 000 – 600 000 natural products have been isolated and characterized over the past two centuries, there may be a 10-fold greater inventory awaiting immediate exploration based on biosynthetic gene cluster predictions. The approach of this book is to codify the chemical logic that underlies each natural product structural class as they are assembled from building blocks of primary metabolism. This second edition integrates many new findings into the sets of principles of the first edition that parsed categories of natural product chemistries into the underlying enzymatic mechanisms and the catalytic machinery for building the varied and complex end product metabolites. New chapters include evaluation of a core set of thermodynamically activated but kinetically stable metabolites that power both primary and secondary metabolic pathways. Also, after decades of uncertainty about the existence of various pericyclase classes, a series of genome mining, heterologous expression, and enzymatic activity characterization have validated a plethora of pericyclases over the past decade. The several types of pericyclases are involved in biosynthetic complexity generation of almost every major category of natural products. This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists. It will also be valuable to bioinformatic and computational biologists, pharmacognocists and chemical ecologists, and bioengineers and synthetic biologists.
In the first biography of philosopher Sidney Hook since his death in 1989, Christopher Phelps vividly describes the neglected early thought and political history of this important New York intellectual. Phelps chronicles Hook's early years and explores the contributions young Hook made to social theory, ethics, politics, epistemology, and discussions of scientific method. 12 photos.
Get comprehensive, practical coverage of both surgical and non-surgical treatment approaches from the world's most trusted authorities in spine surgery and care. Rothman-Simeone and Herkowitz's The Spine, 7th Edition, edited by Drs. Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Jeffrey S. Fischgrund, and Christopher M. Bono, presents state-of-the-art techniques helping you apply today's newest developments in your practice. - Highlights critical information through the use of pearls, pitfalls, and key points throughout the text, as well as more than 2,300 full-color photographs and illustrations. - Offers a newly revised, streamlined format that makes it easier than ever to find the information you need. - Contains new chapters on the clinical relevance of finite element modeling and SI joint surgery. - Includes an expanded section on minimally invasive spine surgery, including recent developments and future directions. - Provides the latest evidence-based research from high-quality studies, including new randomized controlled trials for lumbar stenosis, surgery, fusion, and injections. - Presents the knowledge and expertise of new international contributors, as well as new editorial leadership from Dr. Steven Garfin. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Get the core knowledge in pain medicine you need from one of the most trusted resources in the field. The new fourth edition guides you through every aspect of pain medicine with concise descriptions of evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. From commonly seen pain syndromes, including headaches, trunk pain, orofacial pain, back pain, and extremity pain...through specific pain management challenges such as postoperative pain, pain due to cancer, phantom pain, and pain in the management of AIDS patients...this popular text will equip you with the know-how you need to effectively manage even your most challenging cases. A practical, multidisciplinary approach to pain management makes key concepts and techniques easier to apply to everyday practice. Expert contributors provide the latest knowledge on all aspects of pain management, from general principles through to specific management techniques. Detailed discussions of the latest concepts and treatment plans help you provide the best possible outcomes for all your patients. Extensively updated chapters acquaint you with the most current trends and techniques in pain management. A new section on complications helps you avoid and manage potential pitfalls. A new editorial team ensures that you are getting the freshest, most clinically relevant information available today. New, full-color art clarifies key concepts and techniques.
Dyslexia is a brain-based type of learning disability that specifically impairs a person's ability to read. Although the disorder varies from person to person, common characteristics among people with dyslexia are difficulty with phonological processing (the manipulation of sounds) and/or rapid visual-verbal responding. The syndrome of dyslexia does not imply low intelligence or poor educational potential, and is independent of race and social background. Although dyslexia seems to be more prevalent among males than females, the exact ratio is unknown: the most commonly quoted figures are between 3:1 and 5:1. The evidence suggests that in at least two-thirds of cases, dyslexia has a genetic cause, but in some cases birth difficulties may play a role. Dyslexia may overlap with related conditions such as dyspraxia, attention deficit disorder (with or without hyperactivity) and dysphasia. In childhood, its effects can be misattributed to emotional or behavioural disorders. By adulthood, many dyslexics will have developed sophisticated compensating strategies that may mask their difficulties. This new book presents state-of-the-art research in this dynamic field.
Integrating a contemporary approach to econometrics with the powerful computational tools offered by Stata, this introduction illustrates how to apply econometric theories used in modern empirical research using Stata. The author emphasizes the role of method-of-moments estimators, hypothesis testing, and specification analysis and provides practical examples that show how to apply the theories to real data sets. The book first builds familiarity with the basic skills needed to work with econometric data in Stata before delving into the core topics, which range from the multiple linear regression model to instrumental-variables estimation.
Adolescent Urology and Long-Term Outcomes provides urologistsand pediatric urologists with a comprehensive and expert clinicalguide to the main urologic problems that can occur duringadolescence. Fully covering disorders related to sex and genital development,the kidney, bladder, ureta and urethra, Professor Woodhouse, aworld-leading expert and global pioneer in this fieldsystematically outlines the best clinical practice in the surgicaland medical management of these complex and extremely challengingconditions, as well covering the long-term outcome for thepatient. Given the sensitive nature of these problems and their effect onadolescent patients, attention is paid to the psychological aspectof such disorders: especially how best to manage patientsstruggling to come to terms with what are very personal and complexissues at what is often a difficult and turbulent period of theirlife. Well-illustrated with over 120 figures including step-by-stepsurgical diagrams throughout, chapters will also include a unique“voice of the experts” feature – a runningdialogue between leading experts and Prof Woodhouse on the topic inquestion. This modern, expert guide to adolescent urologic problems fromone of the leading names in the field will be an essential tool formodern-day urologists and urologic surgeons, especially thosespecialising in pediatric patients, as well as pediatricians andendocrinologists.
DIVThe first collection of nonfiction from the author Tony Kushner calls “one of the best novelists writing in the world today” /divDIV Over a thirty-year period, novelist Christopher Bram witnessed, and lived through, the powerful experiences of coming out, the AIDS epidemic, gay marriage, and the social changes that have occurred in lower Manhattan. From the title piece, which maps the state of gay fiction, to “A Body in Books,” about the gay books that changed the author’s life, the essays in Mapping the Territory form a coherent autobiographical account of Bram’s life. This work wouldn’t be complete without “Homage to Mr. Jimmy,” his account of how his novel Father of Frankenstein grew from his imagination and writing into the Oscar-winning movie Gods and Monsters. Mapping the Territory is a thoroughly engaging and compelling look into a great American writer./div
The Malleus Maleficarum, first published in 1486–7, is the standard medieval text on witchcraft and it remained in print throughout the early modern period. Its descriptions of the evil acts of witches and the ways to exterminate them continue to contribute to our knowledge of early modern law, religion and society. Mackay's highly acclaimed translation, based on his extensive research and detailed analysis of the Latin text, is the only complete English version available, and the most reliable. Now available in a single volume, this key text is at last accessible to students and scholars of medieval history and literature. With detailed explanatory notes and a guide to further reading, this volume offers a unique insight into the fifteenth-century mind and its sense of sin, punishment and retribution.
Christopher Hyde continues to carve an indelible niche in the world of international thrillers. This WWII story is filled with actual events, historical figures, and a true-to-life atmosphere and intrigue that pull the reader in and don’t let go. November 1941. Freelance news photographer Jane Todd and Scotland Yard detective inspector Morris Black are recruited by Wild Bill Donovan of the OSS. Their orders are to trace an artifact rumored to exist from the bloody days of the Bolshevik Revolution. The missing relic may hold the key to forging or destroying the balance of power in the war that is sure to involve the U.S. As the long-cold trail heats up for Jane and Black, close on their heels are a brutal Nazi assassin, a mysterious countess with a very shady past, and the lethally charming head of NKVD operations in America. “Hyde’s storytelling is pure genius.”—New York Daily News “[Hyde] draws tension with the skill of a surgeon.”—New York Times bestselling author Michael Connelly
Much of the coverage surrounding the relationship between Indigenous communities and the Crown in Canada has focused on the federal, provincial, and territorial governments. Yet it is at the local level where some of the most important and significant partnerships are being made between Indigenous and non-Indigenous peoples. In A Quiet Evolution, Christopher Alcantara and Jen Nelles look closely at hundreds of agreements from across Canada and at four case studies drawn from Ontario, Quebec, and Yukon Territory to explore relationships between Indigenous and local governments. By analyzing the various ways in which they work together, the authors provide an original, transferable framework for studying any type of intergovernmental partnership at the local level. Timely and accessible, A Quiet Evolution is a call to politicians, policymakers and citizens alike to encourage Indigenous and local governments to work towards mutually beneficial partnerships.
The Sustainable Museum is the first book to outline a coherent strategy for the direction of museums, as it relates to sustainability in the museum and heritage sector. Arguing that museums must place sustainability at the centre of all their activities, if they are to become key actors with a clear societal role, Garthe considers the issues that museums will likely face as they take on their new roles. Presenting case studies from a wide range of museums around the world, the book considers different ways of implementing sustainability in different types and sizes of institutions. Whilst the book clearly outlines the need for change, it also provides guidance about how to change. Garthe does this by considering specific concepts and approaches to sustainability in relation to the different aspects of museum operations. The book includes a hands-on manual for implementing sustainability management in a museum, whilst also considering the challenges practitioners will encounter and considering what the future of the sustainable museum might look like. The Sustainable Museum will be essential reading for museum and heritage professionals around the globe. The book will also be of interest to academics and students engaged in the study of museums, arts and cultural management, business administration, change management or sustainable development.
In the early 1990s, NASA Goddard Space Flight Center started researching and developing autonomous and autonomic ground and spacecraft control systems for future NASA missions. This research started by experimenting with and developing expert systems to automate ground station software and reduce the number of people needed to control a spacecraft. This was followed by research into agent-based technology to develop autonomous ground c- trol and spacecraft. Research into this area has now evolved into using the concepts of autonomic systems to make future space missions self-managing and giving them a high degree of survivability in the harsh environments in which they operate. This book describes much of the results of this research. In addition, it aimstodiscusstheneededsoftwaretomakefutureNASAspacemissionsmore completelyautonomousandautonomic.Thecoreofthesoftwareforthesenew missions has been written for other applications or is being applied gradually in current missions, or is in current development. It is intended that this book should document how NASA missions are becoming more autonomous and autonomic and should point to the way of making future missions highly - tonomous and autonomic. What is not covered is the supporting hardware of these missions or the intricate software that implements orbit and at- tude determination, on-board resource allocation, or planning and scheduling (though we refer to these technologies and give references for the interested reader).
This book explores the relationship between various types of reproduction and the evolutionary process. Starting with the concept of meiosis, George C. Williams states the conditions under which an organism with both sexual and asexual reproductive capacities will employ each mode. He argues that in low-fecundity higher organisms, sexual reproduction is generally maladaptive, and persists because there is no ready means of developing an asexual alternative. The book then considers the evolutionary development of diverse forms of sexuality, such as anisogamy, hermaphroditism. and the evolution of differences between males and females in reproductive strategy. The final two chapters examine the effect of genetic recombination on the evolutionary process itself.
Economics, like most other social sciences, is not a pure discipline. Indeed, it has been enhanced by the fact that there is so much overlap between it and the related fields of business, industrial relations, political science, social psychology, and sociology. This book is the first attempt to explain how work in economics has influenced and benefited from a merging of economic analysis with the research practices of these related fields of study. With contributions from leading economists from around the world, it demonstrates how economics is leading the way toward a more unified social science.
How the far North offered a different kind of terra incognita for the Renaissance imagination. European narratives of the Atlantic New World tell stories of people and things: strange flora, wondrous animals, sun-drenched populations for Europeans to mythologize or exploit. Yet, as Christopher Heuer explains, between 1500 and 1700, one region upended all of these conventions in travel writing, science, and, most unexpectedly, art: the Arctic. Icy, unpopulated, visually and temporally “abstract,” the far North—a different kind of terra incognita for the Renaissance imagination—offered more than new stuff to be mapped, plundered, or even seen. Neither a continent, an ocean, nor a meteorological circumstance, the Arctic forced visitors from England, the Netherlands, Germany, and Italy, to grapple with what we would now call a “non-site,” spurring dozens of previously unknown works, objects, and texts—and this all in an intellectual and political milieu crackling with Reformation debates over art's very legitimacy. In Into the White, Heuer uses five case studies to probe how the early modern Arctic (as site, myth, and ecology) affected contemporary debates over perception and matter, representation, discovery, and the time of the earth—long before the nineteenth century Romanticized the polar landscape. In the far North, he argues, the Renaissance exotic became something far stranger than the marvelous or the curious, something darkly material and impossible to be mastered, something beyond the idea of image itself.
The lifestyles and socio-economic status that are prevalent in regions of the world with limited resources form the background for the unique features of neoplastic diseases in these areas, where the majority of the world population lives. The predominance of the world’s retroviral burden of in these areas further compounds the nature and challenges of the cancer there. Much of the international cancer literature covers the nature and challenges of the disease as seen in high-income regions of the world, thereby giving a skewed view of the global cancer challenges. As the low- and middle-income regions of the world transition from communicable to non communicable disease patterns, there is a need for a corresponding paradigm shift, with increased emphasis on what the world needs to know about non communicable diseases, including cancer, where the disease is hitherto poorly documented. The main goal of the proposed book is to contribute to this outcomes.
The Transatlantic Collapse of Urban Renewal examines how postwar thinkers from both sides of the Atlantic considered urban landscapes radically changed by the political and physical realities of sprawl, urban decay, and urban renewal. With a sweep that encompasses New York, London, Berlin, Philadelphia, and Toronto, among others, Christopher Klemek traces changing responses to the challenging issues that most affected the lives of the world’s cities. In the postwar decades, the principles of modernist planning came to be challenged—in the grassroots revolts against the building of freeways through urban neighborhoods, for instance, or by academic critiques of slum clearance policy agendas—and then began to collapse entirely. Over the 1960s, several alternative views of city life emerged among neighborhood activists, New Left social scientists, and neoconservative critics. Ultimately, while a pessimistic view of urban crisis may have won out in the United States and Great Britain, Klemek demonstrates that other countries more successfully harmonized urban renewal and its alternatives. Thismuch anticipated book provides one of the first truly international perspectives on issues central to historians and planners alike, making it essential reading for anyone engaged with either field.
For more than 30 years, Practical Management of Pain has offered expert guidance to both clinicians and trainees, covering every aspect of acute and chronic pain medicine for adult and pediatric patients. The fully revised 6th Edition brings you fully up to date with new developments in patient evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. Edited by a team of renowned pain clinicians led by Dr. Honorio Benzon, this authoritative reference is a comprehensive, practical resource for pain diagnosis and treatment using a variety of pharmacologic and physical modalities. - Presents a wealth of information in a clearly written, easily accessible manner, enabling you to effectively assess and draw up an optimal treatment plan for patients with acute or chronic pain. - Takes a practical, multidisciplinary approach, making key concepts and techniques easier to apply to everyday practice. - Shares the knowledge and expertise of global contributors on all facets of pain management, from general principles to specific management techniques. - Discusses the latest, best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents such as topical analgesics. - Covers recent global developments regarding opioid induced hyperalgesia, neuromodulation and pain management, and identification of specific targets for molecular based pain. - Includes current information on the use of cannabinoids in pain management and related regulatory, professional, and legal considerations. - Includes the latest guidelines on facet injections and safety of contrast agents. - Provides new, evidence-based critical analysis on treatment modality outcomes and the latest information on chronic pain as a result of surgical interventions. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Up to date and comprehensive, the New Edition of Fletcher's renowned Diagnostic Histopathology of Tumors provides you with today's best knowledge on the pathologic diagnosis of human tumors. This 3rd edition incorporates all of the latest ancillary diagnostic and prognostic techniques so you can effectively evaluate and confidently interpret suspected tumor specimens. Plus, more than 50 internationally recognized authorities and over 3,100 full-color illustrations provide you with an up-to-date account of tumor morphology, the application of modern diagnostic techniques (including molecular genetics), and key aspects of differential diagnosis. Features over 3,000 high-quality full-color illustrations, providing visual guidance to each tumor or tumor-like entity. Presents correlations of gross appearances to microscopic findings for virtually every tumor type. Includes detailed discussions of differential diagnosis. Provides full coverage of all the latest classification schemes. Incorporates the latest advances in molecular biology and immunohistochemistry throughout. Presents an increased focus on everyday diagnostic problems you are likely to encounter. Features extensively rewritten gynecology and hematology chapters. Uses additional diagnostic flow charts and summary tables for easy retrieval of information. Includes more differential diagnosis tables for better recognition and evaluation of similar looking entities.
Circadian rhythms, the biological oscillations based around our 24-hour clock, have a profound effect on human physiology and healthy cellular function. Circadian Rhythms: Health and Disease is a wide-ranging foundational text that provides students and researchers with valuable information on the molecular and genetic underpinnings of circadian rhythms and looks at the impacts of disruption in our biological clocks in health and disease. Circadian Rhythms opens with chapters that lay the fundamental groundwork on circadian rhythm biology. Section II looks at the impact of circadian rhythms on major organ systems. Section III then turns its focus to the central nervous system. The book then closes with a look at the role of biological rhythms in aging and neurodegeneration. Written in an accessible and informative style, Circadian Rhythms: Health and Disease,will be an invaluable resource and entry point into this fascinating interdisciplinary field that brings together aspects of neuroscience, cell and molecular biology, and physiology.
Obtain all the core knowledge in pain management you need from one of the most trusted resources in the field. The new edition of Practical Management of Pain gives you completely updated, multidisciplinary overview of every aspect of pain medicine, including evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. In print and online, it is all the expert guidance necessary to offer your patients the best possible relief. "In summary, this is the best explanation of what lies behind MRI that I have read, taking what can be a dry subject and making it readily understandable and really interesting. I would recommend it to anyone starting their MRI training and anyone trying to teach MRI to others." Reviewed by RAD Magazine, June 2015 Understand and apply the latest developments in pain medicine with brand-new chapters covering disability assessment, central post-stroke pain, chronic widespread pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics). Access up-to-the-minute knowledge on all aspects of pain management, from general principles to specific management techniques, with contributions from renowned experts in the field. Read the full text and view all the images online at expertconsult.com. Understand and apply the latest developments in pain management with brand-new chapters covering disability assessment, central post-stroke pain, widespread chronic pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics).
Completely updated and now in full color throughout with many new illustrations, the Fourth Edition of this practical manual is a step-by-step guide to performing regional anesthesia procedures. This edition's improved and expanded program of illustrations includes detailed full-color anatomical drawings and clinical photographs correlated to drawings of needle placements. The state-of-the-art coverage includes the latest advances in ultrasound-guided procedures and continuous catheterization. A consistent outline format throughout this edition makes the text accessible and easy to use. Chapters cover all areas of regional anesthesia, including peripheral, central, obstetric, pediatric, ophthalmic, head and face, ambulatory anesthesia, and postoperative pain management.
This book is a companion text to Active Control of Sound by P.A. Nelson and S.J. Elliott, also published by Academic Press. It summarizes the principles underlying active vibration control and its practical applications by combining material from vibrations, mechanics, signal processing, acoustics, and control theory. The emphasis of the book is on the active control of waves in structures, the active isolation of vibrations, the use of distributed strain actuators and sensors, and the active control of structurally radiated sound. The feedforward control of deterministic disturbances, the active control of structural waves and the active isolation of vibrations are covered in detail, as well as the more conventional work on modal feedback. The principles of the transducers used as actuateors and sensors for such control strategies are also given an in-depth description. The reader will find particularly interesting the two chapters on the active control of sound radiation from structures: active structural acoustic control. The reason for controlling high frequency vibration is often to prevent sound radiation, and the principles and practical application of such techniques are presented here for both plates and cylinders. The volume is written in textbook style and is aimed at students, practicing engineers, and researchers. - Combines material from vibrations, signal processing, mechanics, and controls - Summarizes new research in the field
Now Available for the First Time in Paperback! This unique volume provides a definitive overview of modern and traditional brewing fermentation. Written by two experts with unrivalled experience from years with a leading international brewer, coverage includes all aspects of brewing fermentation together with the biochemistry, physiology and genetics of brewers' yeast. Brewing Yeast and Fermentation is unique in that brewing fermentation and yeast biotechnology are covered in detail from a commercial perspective. Now available for the first time in paperback, the book is aimed at commercial brewers and their ingredient and equipment suppliers (including packaging manufacturers). It is also an essential reference source for students on brewing courses and workers in research and academic institutions. Definitive reference work and practical guide for the industry. Highly commercially relevant yet academically rigorous. Authors from industry leading brewers.
Climate change is one of the greatest threats facing humanity, a definitive manifestation of the well-worn links between progress and devastation. This book explores the complex relationship that the corporate world has with climate change and examines the central role of corporations in shaping political and social responses to the climate crisis. The principal message of the book is that despite the need for dramatic economic and political change, corporate capitalism continues to rely on the maintenance of 'business as usual'. The authors explore the different processes through which corporations engage with climate change. Key discussion points include climate change as business risk, corporate climate politics, the role of justification and compromise, and managerial identity and emotional reactions to climate change. Written for researchers and graduate students, this book moves beyond descriptive and normative approaches to provide a sociologically and critically informed theory of corporate responses to climate change.
Our knowledge of Greek history rests largely on literary texts - not merely historians (especially Herodotus, Thucylides and Xenephon), but also tragedies, comedies, speeches, biographies and philosophical works. These texts are themselves among the most skilled and highly wrought productions of a brilliant rhetorical culture. How is the historian to use them? This book addresses this problem by taking a series of extended test-cases, and discussing how we should and should not try to exploit the texts. In some instances we can investigate 'what really happened', and the ways in which the texts manipulate, remould, or colour it according to their own rhetorical strategies; in others the most illuminating aspect may be those strategies themselves, and what they tell us about the culture - how it figured questions of sex and gender, politics, citizenship and the city, the law and the courts and how wars happen. Literary Texts and the Greek Historian concentrates on Athens in the second half of the fifth-century, when many of the principal genres came together, but includes some examples from earlier (Aeschylus ^Oresteia) and later (including Aristotles poetics). Literary Texts and the Greek Historian examines the range of responses to these texts and suggests new ways in which literary criticism can illuminate the society from which these texts sprang.
Proton Transfer Reaction Mass Spectrometry (PTR-MS) is a rapidly growing analytical technique for detecting and identifying very small quantities of chemical compounds in air. It has seen widespread use in atmospheric monitoring and food science and shows increasing promise in applications such as industrial process monitoring, medical science and in crime and security scenarios. Written by leading researchers, this is the first book devoted to PTR-MS and it provides a comprehensive account of the basic principles, the experimental technique and various applications, thus making this book essential reading for researchers, technicians, postgraduate students and professionals in industry. The book contains nine chapters and is divided into two parts. The first part describes the underlying principles of the PTR-MS technique, including • the relevant ion-molecule chemistry • thermodynamics and reaction kinetics • a discussion of ion sources, drift tubes and mass spectrometers • practical aspects of PTR-MS, including calibration. The second part of the book turns its attention to some of the many applications of PTR-MS, demonstrating the scope and benefits, as well as the limitations, of the technique. The chapters that make up the second part of the book build upon the material presented in the first part and are essentially self-contained reviews focusing on the following topics: • environmental science • food science • medicine • homeland security, and • applications of PTR-MS in liquid analysis.
In the last decades, violent non-state actors (VNSAs) such as rebel and terrorist organizations have proved their capacity to break international law. The international community, particularly the United Nations (UN), has reacted to this development by redirecting its conflict resolution efforts to these non-state entities. This has turned targeted sanctions into one of the most vital and indispensable foreign policy tools available to the UN Security Council in combating terrorism and contributing to the peaceful resolution of (intra-state) conflicts. Despite the UN Security Council’s growing tendency to sanction VNSAs, there has been little research analyzing the effects of UN targeted sanctions on these non-government actors. This book seeks to fill this gap and shifts the focus on non-state actors by ascertaining the general mechanisms through and conditions under which UN targeted sanctions imposed on VNSAs tend to be effective. The tripartite empirical analysis combining quantitative and qualitative research methods demonstrates that the state-centric understanding of how sanctions work is not simply applicable to the effective sanctioning of violent non-state actors such as rebel and terrorist movements.
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