Diagnose tumors with confidence with Diagnostic Histopathology of Tumors, 4th Edition. Dr. Christopher Fletcher's renowned reference provides the advanced, expert guidance you need to evaluate and interpret even the most challenging histopathology specimens more quickly and accurately. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Diagnose efficiently and effectively using diagnostic flow charts, correlations of gross appearances to microscopic findings, and differential diagnosis tables for better recognition and evaluation of similar-looking entities. Employ immunohistochemistry, molecular and genetic diagnostic tests, and other modern techniques as well as the best morphologic diagnostic methods to effectively identify each tumor or tumor-like entity. Utilize new, clinically important molecular genetic data and updated classification schemes to help guide treatment and targeted therapy. Apply the latest techniques and diagnostic criteria with completely rewritten chapters on Small and Large Intestines, Heart, Larynx and Trachea, Ear, and Peritoneum. Find critical information quickly thanks to more tables and bulleted lists throughout.
Heterocyclic compounds play a vital role in the metabolism of living cells. Their practical applications range from extensive clinical use to fields as diverse as agriculture, photography, biocide formulation and polymer science. Written by leading scholars and industry experts, the Handbook of Heterocyclic Chemistry is thoroughly updated with over 50% new content. It has been rewritten with a new expanded author team, who have carefully distilled essential information on the reactivity, structure and synthesis of heterocycles from the 2008 major reference work Comprehensive Heterocyclic Chemistry III. To bring the work up to date the author team have also added new synthetic examples and structures, key applications and new references from 2008-2010. Contains more than 1500 clearly drawn structures and reactions. The highly systematic coverage given to the subject makes this one of the most authoritative single-volume accounts of modern heterocyclic chemistry available and should be useful reference for those teaching a heterocyclic course. - Covers the structure, reactivity and synthesis of all heterocyclic compounds as distilled from the larger 15-volume reference work - Saves researchers time when they require important information on heterocycles--speeding them to thousands of clearly drawn chemical structures and pertinent reviews by leading experts - Features 35% new material to compliment the completely revised text
In general, little is known about the representation theory of quantum groups (resp., algebraic groups) when l (resp., p ) is smaller than the Coxeter number h of the underlying root system. For example, Lusztig's conjecture concerning the characters of the rational irreducible G -modules stipulates that p=h. The main result in this paper provides a surprisingly uniform answer for the cohomology algebra H (u ? ,C) of the small quantum group.
Combines More Than 40 Years of Expert ExperienceComputational modelling and simulation methods have a wide range of applications in hydraulic and coastal engineering. Computational Modelling in Hydraulic and Coastal Engineering provides an introductory but comprehensive coverage of these methods. It emphasizes the use of the finite differences meth
This volume contains the proceedings of the AMS-IMS-SIAM Joint Summer Research Conference on Nielsen Theory and Dynamical Systems, held in June 1992 at Mount Holyoke College. Focusing on the interface between Nielsen fixed point theory and dynamical systems, this book provides an almost complete survey of the state of the art of Nielsen theory. Most of the articles are expository and provide references to more technical works, making them accessible to both graduate students and researchers in algebraic topology, fixed point theory, and dynamical systems.
* The first book focused solely on data parsing, a task commonly deemed Perl’s greatest strength * Couples an introduction to data parsing concepts and techniques with practical instruction regarding the key Perl modules capable of facilitating often complex parsing tasks * The author, Christopher Frenz, is a bioinformaticist and expert on Perl and scientific computing
Recently, there has been considerable research interest in neural network control of robots, and satisfactory results have been obtained in solving some of the special issues associated with the problems of robot control in an “on-and-off” fashion. This book is dedicated to issues on adaptive control of robots based on neural networks. The text has been carefully tailored to (i) give a comprehensive study of robot dynamics, (ii) present structured network models for robots, and (iii) provide systematic approaches for neural network based adaptive controller design for rigid robots, flexible joint robots, and robots in constraint motion. Rigorous proof of the stability properties of adaptive neural network controllers is provided. Simulation examples are also presented to verify the effectiveness of the controllers, and practical implementation issues associated with the controllers are also discussed.
The field of medicinal/aromatic plant breeding is growing and changing?this resource will help you stay up to date! In this essential book, researchers from large and small laboratories and institutions throughout Europe and the Mediterranean region explore recent developments in the selection and breeding of aromatic and medicinal plants. They take varied approaches?from traditional breeding to the use of molecular markers?and complement them with up-to-date information on biodiversity and resource conservation. From the editors: ?It is widely recognized that a strategy of `conservation through use,? by which plant collection via wild harvesting is replaced by controlled cultivation, is the best way forward if we are to balance human demands with the necessary conservation of the biodiversity represented by these species. That provides one major driving force for research in this field. Another concerns the very real need for improving the quality control of products on the market, both to satisfy consumer demand and to conform with the (justifiably) increasing requirements for standardization and precise identification of the composition of the plant materials being sold for human use. We hope that this volume will give readers a taste of the exciting developments in the field.? Breeding Research on Aromatic and Medicinal Plants examines: breeding for resistance and abiotic factors manipulating natural product accumulation through genetic engineering biochemical and molecular regulation of essential oil accumulation economic and legal considerations that breeders will encounter the ethical aspects of breeding these plants
A story that helps us see the unique goodness in each person. Every town has its secrets. When it becomes known that Mr. Nicholas, the eccentric owner of the local hardware store, is somehow involved with reindeer, toys, and children, the town becomes more and more suspicious that this man is more than just a clerk on Main Street. JB, a clever, open ten-year-old boy with Down syndrome, is able to figure out the secret from the first time Mr. Nicholas gives him a chocolate deer wrapped in gold foil. JB’s father and mother, both cynical and on the brink of divorce, follow the adventures of JB as he flies on the back of a reindeer, feeds Mister Rogers’s fish, and defines what can be forgotten by those who are too busy to remember the magic of Christmas, cuckoo-clocks, and love.
Molecular Biology of Cancer has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It continues to provide a detailed overview of the process which lead to the development and proliferation of cancer cells, including the techniques available for their study. It also describes the means by which tumor suppressor genes and oncogenes may be used in the diagnosis and in determining the prognosis of a wide variety of cancers, including breast, genitourinary, lung and gastrointestinal cancer.
Multidimensional Grief Therapy (MGT) provides counselors, social workers, psychologists, and psychiatrists (as well as students in these fields) with a flexible program for assessing and supporting children and adolescents who have experienced bereavement. MGT is a strength-based intervention, designed to reduce unhelpful grief reactions that prevent adjustment, and promote adaptive grief reactions that enable children to cope better after a death. It also reduces associated symptoms of psychological distress and helps bereaved children and adolescents lead healthy, happy, productive lives. As young people grieve in different ways and “one-size-fits-all” treatments often lack effectiveness, MGT uses an assessment-driven, two-phased approach to effectively address the unique mental health needs of diverse youth. This manual provides a wealth of activities and handouts designed specifically to engage and empower youth after experiencing a death, including under traumatic circumstances.
The authors examine several topical subjects, commencing with a general introduction to path integrals in quantum mechanics and the group theoretical backgrounds for path integrals. Applications of harmonic analysis, polar coordinate formulation, various techniques and path integrals on SU(2) and SU(1, 1) are discussed. Soluble examples presented include particle-flux system, a pulsed oscillator, magnetic monopole, the Coulomb problem in curved space and others.The second part deals with the SU(2) coherent states and their applications. Construction and generalization of the SU(2) coherent states, formulation of coherent path integrals for spin and unitary spin, and semiclassical quantization are presented. Applications are made to the study of quantum fluctuation, the nonlinear field model and phase holonomy.The final chapters present the theory of the SU(1, 1) coherent states and their applications. The radial coulomb problem, the Morse oscillator, and the large-N approximation are discussed. Applications to problems in quantum optics such as squeezed states, interaction with the squeezed vacuum states, and phase operator formalism are also included.This book will be useful as an introduction to the subject as well as a valuable work of reference.
Inventory Management in Multi-Echelon Networks presents methods to plan inventory in distribution networks. By holistically looking at the supply chain, it shows how safety stocks across all echelons can be optimized if inventory of all levels is taken into consideration. The gap between the existence of advanced inventory planning methods and their low penetration in the industry was the motivation for this book. Christopher Grob develops essential algorithms that companies can use for network inventory planning and highlights achievable implementation benefits. The work of the author was inspired by the needs of an after sales supply chain of a large automotive company. This company supplies customers all over the world with spare parts and operates a distribution network with more than 100 warehouses. This supply chain faces two particular challenges: demand is highly uncertain and customers expect a high service level. About the Author Christopher Grob works in after sales supply chain management at a major German automotive company. He is responsible for the functional development of inventory planning systems for the spare parts business. He is an expert in the field of inventory management.
Computational aeroacoustics (CAA) is a relatively new research area. CAA algorithms have developed rapidly and the methods have been applied in many areas of aeroacoustics. The objective of CAA is not simply to develop computational methods but also to use these methods to solve practical aeroacoustics problems and to perform numerical simulation of aeroacoustic phenomena. By analysing the simulation data, an investigator can determine noise generation mechanisms and sound propagation processes. This is both a textbook for graduate students and a reference for researchers in CAA and as such is self-contained. No prior knowledge of numerical methods for solving partial differential equations (PDEs) is needed, however, a general understanding of partial differential equations and basic numerical analysis is assumed. Exercises are included and are designed to be an integral part of the chapter content. In addition, sample computer programs are included to illustrate the implementation of the numerical algorithms.
Clinical Radiology of the Horse is the best-selling, practical guide to all areas of equine radiography and radiology written by an experienced group of clinicians with a broad range of backgrounds. Offers an atlas of normal and clinical images, as well as a comprehensive guide to techniques, equipment, positioning, and interpretation for general veterinary practitioners and specialists in imaging and orthopaedics Updates to this fourth edition fully reflect the move to digital imaging with many new figures in the book and major revisions to the chapters on the head, thorax, and abdomen Contains expanded coverage of the foot, pastern, and fetlock (now in separate chapters) Includes a password-protected website with all the images from the book as well as over 200 additional images with examples of more subtle lesions, more fractures, correct technique and positioning versus incorrect, immature horses, progression of disease, and pathological images
Essentials of Computational Chemistry provides a balanced introduction to this dynamic subject. Suitable for both experimentalists and theorists, a wide range of samples and applications are included drawn from all key areas. The book carefully leads the reader thorough the necessary equations providing information explanations and reasoning where necessary and firmly placing each equation in context.
Written by experts, Digital Terrain Modeling: Principles and Methodology provides comprehensive coverage of recent developments in the field. The topics include terrain analysis, sampling strategy, acquisition methodology, surface modeling principles, triangulation algorithms, interpolation techniques, on-line and off-line quality control in data a
This established textbook provides an accessible but comprehensive introduction to the quantum nature of light and its interaction with matter. The field of quantum optics is covered with clarity and depth, from the underlying theoretical framework of field quantization, atom–field interactions, and quantum coherence theory, to important and modern applications at the forefront of current research such as quantum interferometry, squeezed light, quantum entanglement, cavity quantum electrodynamics, laser-cooled trapped ions, and quantum information processing. The text is suitable for advanced undergraduate and graduate students and would be an ideal main text for a course on quantum optics. This long-awaited second edition builds upon the success of the first edition, including many new developments in the field, particularly in the area of quantum state engineering. Additional homework problems have been added, and content from the first edition has been updated and clarified throughout.
In the 5th century BCE, Herodotus wrote the first known Western history to build on the tradition of Homeric storytelling, basing his text on empirical observations and arranging them systematically. Herodotus and the Question Why offers a comprehensive examination of the methods behind the Histories and the challenge of documenting human experiences, from the Persian Wars to cultural traditions. In lively, accessible prose, Christopher Pelling explores such elements as reconstructing the mentalities of storyteller and audience alike; distinctions between the human and the divine; and the evolving concepts of freedom, democracy, and individualism. Pelling traces the similarities between Herodotus's approach to physical phenomena (Why does the Nile flood?) and to landmark events (Why did Xerxes invade Greece? And why did the Greeks win?), delivering a fascinating look at the explanatory process itself. The cultural forces that shaped Herodotus's thinking left a lasting legacy for us, making Herodotus and the Question Why especially relevant as we try to record and narrate the stories of our time and to fully understand them.
This book provides a comprehensive review of what receptors do in the nervous system, how they do it, the mechanisms by which receptor function is regulated, and the consequences of normal and abnormal receptor function. It contains a series of interrelated chapters describing key neurotransmitter receptors, protein kinases, and protein phosphatases, and details their expression and composition in the development of the central nervous system (CNS).
Get comprehensive, practical coverage of both surgical and non-surgical treatment approaches from the world's most trusted authorities in spine surgery and care. Rothman-Simeone and Herkowitz's The Spine, 7th Edition, edited by Drs. Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Jeffrey S. Fischgrund, and Christopher M. Bono, presents state-of-the-art techniques helping you apply today's newest developments in your practice. - Highlights critical information through the use of pearls, pitfalls, and key points throughout the text, as well as more than 2,300 full-color photographs and illustrations. - Offers a newly revised, streamlined format that makes it easier than ever to find the information you need. - Contains new chapters on the clinical relevance of finite element modeling and SI joint surgery. - Includes an expanded section on minimally invasive spine surgery, including recent developments and future directions. - Provides the latest evidence-based research from high-quality studies, including new randomized controlled trials for lumbar stenosis, surgery, fusion, and injections. - Presents the knowledge and expertise of new international contributors, as well as new editorial leadership from Dr. Steven Garfin. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Late in 1755, an army of British regulars and Massachusetts volunteers completed one of the cruelest, most successful military campaigns in North American history, capturing and deporting seven thousand French-speaking Catholic Acadians from the province of Nova Scotia, and chasing an equal number into the wilderness of eastern Canada. Thousands of Acadians endured three decades of forced migrations and failed settlements that shuttled them to the coasts of South America, the plantations of the Caribbean, the frigid islands of the South Atlantic, the swamps of Louisiana, and the countryside of central France. The Acadian Diaspora tells their extraordinary story in full for the first time, illuminating a long-forgotten world of imperial desperation, experimental colonies, and naked brutality. Using documents culled from archives in France, Great Britain, Canada, and the United States, Christopher Hodson reconstructs the lives of Acadian exiles as they traversed oceans and continents, pushed along by empires eager to populate new frontiers with inexpensive, pliable white farmers. Hodson's compelling narrative situates the Acadian diaspora within the dramatic geopolitical changes triggered by the Seven Years' War. Faced with redrawn boundaries and staggering national debts, imperial architects across Europe used the Acadians to realize radical plans: tropical settlements without slaves, expeditions to the unknown southern continent, and, perhaps strangest of all, agricultural colonies within old regime France itself. In response, Acadians embraced their status as human commodities, using intimidation and even violence to tailor their communities to the superheated Atlantic market for cheap, mobile labor. Through vivid, intimate stories of Acadian exiles and the diverse, transnational cast of characters that surrounded them, The Acadian Diaspora presents the eighteenth-century Atlantic world from a new angle, challenging old assumptions about uprooted peoples and the very nature of early modern empire.
This lavishly illustrated operative atlas consists of detailed, step-by-step descriptions of the procedures used in reconstruction of the female urinary tract from the kidney to the urethra. It is based on the extensive operative experience of two very experienced reconstructive urologists. The procedures described have been devised compeletely afresh or considerably developed during the course of many thousands of operations and thus represent a unique collection. Many of the procedures and "tips" have not been published before. The approach taken throughout the book is a functional one. The basic principles underlying reconstrucive urology are outlined and emphasis is placed on the fact that the logic of each procedure is dictated by a thorough understanding of the particular functional abnormality involved. In addition there is a wealth of practical tips, observations and clinical pearls built up over many years of surgical experience which help to reduce complications and make operations easier. Each operative procedure is described by a sequence of colour photographs with running captions explaining the pitfalls and points of particular importance at each stage. It will be an indispensible guide to reconstructive urology for urologists and gynaecologists alike.
Ever since the discovery of blood types early in the last century, transfusion medicine has evolved at a breakneck pace. This second edition of Blood Banking and Transfusion Medicine is exactly what you need to keep up. It combines scientific foundations with today's most practical approaches to the specialty. From blood collection and storage to testing and transfusing blood components, and finally cellular engineering, you'll find coverage here that's second to none. New advances in molecular genetics and the scientific mechanisms underlying the field are also covered, with an emphasis on the clinical implications for treatment. Whether you're new to the field or an old pro, this book belongs in your reference library. Integrates scientific foundations with clinical relevance to more clearly explain the science and its application to clinical practice. Highlights advances in the use of blood products and new methods of disease treatment while providing the most up-to-date information on these fast-moving topics Discusses current clinical controversies, providing an arena for the discussion of sensitive topics. Covers the constantly changing approaches to stem cell transplantation and brings you the latest information on this controversial topic.
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