The ever-present possibility of death forces upon us the question of life's meaning and for this reason death has been a central concern of philosophers throughout history. From Socrates to Heidegger, philosophers have grappled with the nature and significance of death. In "Annihilation", Christopher Belshaw explores two central questions at the heart of philosophy's engagement with death: what is death; and is it bad that we die? Belshaw begins by distinguishing between literal and metaphorical uses of the term and offers a unified and biological account of death, denying that death brings about non-existence. How our death relates to the death of the brain is explored in detail. Belshaw considers the common-sense view that death is often bad for us by examining the circumstances that might make it bad as well as the grounds for thinking that one death can be worse than another. In addition, Belshaw explores whether we can be harmed after we die and before we were born. The final chapters explore whether we should prevent more deaths and whether, via cryonics, brain transplants, data storage, we might cheat death. Throughout Belshaw shows how questions of personhood and life's value are bound up with our views on the sense and significance of death. "Annihilation's" in-depth analysis and insightful exposition will be welcomed not only by philosophers working on the metaphysics of death but also by students and scholars alike looking for a foundation for discussions of the ethics of abortion, euthanasia, life-support and suicide.
This is the first modern history of one of the most famous schools in the English-speaking world. It takes an even-handed approach, covering the schools failings as well as its successes. It includes frank discussions of Harrow's financial, educational, and sexual scandals along with a survey of its many great moments as the school of Byron, Churchill (and six other prime ministers), and Nehru.
The region of Alsace, located between the hereditary enemies of France and Germany, served as a trophy of war four times between 1870–1945. With each shift, French and German officials sought to win the allegiance of the local populace. In response to these pressures, Alsatians invoked regionalism—articulated as a political language, a cultural vision, and a community of identity—not only to define and defend their own interests against the nationalist claims of France and Germany, but also to push for social change, defend religious rights, and promote the status of the region within the larger national community. Alsatian regionalism however, was neither unitary nor unifying, as Alsatians themselves were divided politically, socially, and culturally. The author shows that the Janus-faced character of Alsatian regionalism points to the ambiguous role of regional identity in both fostering and inhibiting loyalty to the nation. Finally, the author uses the case of Alsace to explore the traditional designations of French civic nationalism versus German ethnic nationalism and argues for the strong similarities between the two countries’ conceptions of nationhood.
This second edition integrates many new findings into the underlying enzymatic mechanisms and the catalytic machinery for building the varied and complex end product metabolites. This text will serve as a reference point for chemists of every subdiscipline, including synthetic organic chemists and medicinal chemists.
Get comprehensive, practical coverage of both surgical and non-surgical treatment approaches from the world's most trusted authorities in spine surgery and care. Rothman-Simeone and Herkowitz's The Spine, 7th Edition, edited by Drs. Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Jeffrey S. Fischgrund, and Christopher M. Bono, presents state-of-the-art techniques helping you apply today's newest developments in your practice. - Highlights critical information through the use of pearls, pitfalls, and key points throughout the text, as well as more than 2,300 full-color photographs and illustrations. - Offers a newly revised, streamlined format that makes it easier than ever to find the information you need. - Contains new chapters on the clinical relevance of finite element modeling and SI joint surgery. - Includes an expanded section on minimally invasive spine surgery, including recent developments and future directions. - Provides the latest evidence-based research from high-quality studies, including new randomized controlled trials for lumbar stenosis, surgery, fusion, and injections. - Presents the knowledge and expertise of new international contributors, as well as new editorial leadership from Dr. Steven Garfin. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Known for its clear writing style, easy-to-navigate format, and authoritative coverage of tumor pathology, Dr. Christopher Fletcher's Diagnostic Histopathology of Tumors, 5th Edition, remains your go-to source for accurate, efficient evaluation and interpretation of histopathology specimens. This highly regarded reference provides superbly illustrated information on pathogenesis, diagnostic criteria, molecular/cytogenetic findings, and prognosis on the neoplastic diseases most likely to be encountered by general surgical pathologists, and helps you stay current with the latest diagnostic tumor markers to assist in daily sign-out. - Discusses the latest developments in immunohistochemistry, molecular genetics, targeted therapy/personalized medicine, and prognostic/predictive markers to assist in the diagnosis of the complete range of neoplastic entities. - Includes coverage of newly described variants and new histologic entities. - Covers all modern diagnostic techniques while retaining a strong emphasis on morphologic diagnosis, which remains the cornerstone of diagnosis for most lesions. - Features thousands of high-quality photographs, photomicrographs, and artwork throughout. - Incorporates the latest TNM and WHO classification and staging systems. - Contains diagnostic flow charts, correlations of gross appearances to microscopic findings, and differential diagnosis tables for better recognition and evaluation of similar-looking entities. - Shares the knowledge and expertise of internationally renowned experts in tumor pathology, including Dr. Christopher Fletcher, as well as numerous global authorities in the field.
Up to date and comprehensive, the New Edition of Fletcher's renowned Diagnostic Histopathology of Tumors provides you with today's best knowledge on the pathologic diagnosis of human tumors. This 3rd edition incorporates all of the latest ancillary diagnostic and prognostic techniques so you can effectively evaluate and confidently interpret suspected tumor specimens. Plus, more than 50 internationally recognized authorities and over 3,100 full-color illustrations provide you with an up-to-date account of tumor morphology, the application of modern diagnostic techniques (including molecular genetics), and key aspects of differential diagnosis. Features over 3,000 high-quality full-color illustrations, providing visual guidance to each tumor or tumor-like entity. Presents correlations of gross appearances to microscopic findings for virtually every tumor type. Includes detailed discussions of differential diagnosis. Provides full coverage of all the latest classification schemes. Incorporates the latest advances in molecular biology and immunohistochemistry throughout. Presents an increased focus on everyday diagnostic problems you are likely to encounter. Features extensively rewritten gynecology and hematology chapters. Uses additional diagnostic flow charts and summary tables for easy retrieval of information. Includes more differential diagnosis tables for better recognition and evaluation of similar looking entities.
Christopher Peacocke examines the problem of knowing whether human beings can really know about the past, about what they are thinking, about what might be and whether freedom is really possible.
This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.
In 1949, Karl Barth confidently upholds a high doctrine of divine providence, main-taining God's control of every event in history. His argument is at once cheerful, but also defiant in the face of a Europe that is war-weary and doubtful of the full sovereignty of God. Barth's movement to praise God shows his affin-ity for the Reformed theological tradition. While Barth often distances himself from his Calvinist predecessors in important ways, he sees his own view of providence to be a positive reworking of the Reformed position in order to maintain what he un-derstands as its most important insights: the praiseworthiness of the God of provi-dence and the doxology of the creature. Doxological Theology investigates how the theologian, in response to the praiseworthy God of the Reformed tradition, is ex-pected to pray his or her way through the doctrine of providence.
There is a growing body of knowledge revealing a sweeping array of connections between public health and green infrastructure – but not until now have the links between them been brought together in one comprehensive book. Green Infrastructure and Public Health provides an overview of current research and theories of the ecological relationships and mechanisms by which the environment influences human health and health behaviour. Covering a broad spectrum of contemporary understanding, Coutts outlines: public health models that explicitly promote the importance of the environment to health ways in which the quality of the landscape is tied to health challenges of maintaining viable landscapes amidst a rapidly changing global environment This book presents the case for fundamental human dependence on the natural environment and creates a bridge between contemporary science on the structure and form of a healthy landscape and the myriad ways that a healthy landscape supports healthy human beings. It presents ideal reading for students and practitioners of landscape architecture, urban design, planning, and health studies.
No matter how careful we are at using metals in industrial processes, some level of human exposure is unavoidable. Countless metals are obtained through mining and smelting activities that amplify their distribution throughout the environment. Applications of metals in industry, medicine, and agriculture have increased our exposure. These metals are not merely an occupational hazard for those working with them-they affect consumers and anyone exposed through environmental contamination. Even worse, they cannot be destroyed and are thus non-biodegradable. The blades we use, the pots and pans we cook with, children's face paint, and facial makeup contain toxic metals. Toxic heavy metals are also found in cigarettes, gourmet foods such as seasonings, fish, and chocolates. When you sprinkle a dish with Himalayan sea salt, you may end up ingesting toxic metals such as arsenic, cadmium and lead.
Extracorporeal circulation has become firmly established as an invaluable and routine adjunct to cardiac and vascular surgery. Since its introduction in 1953, the technique has evolved rapidly with advancing technology leading to improvements in and simplification of the equipment involved. Developments in the understanding and application of basic science have also had a huge impact as our understanding of the complex anatomy, biochemistry, pharmacology and pathophysiology of the heart continues to grow. It is these advances in both technology and science that form the basis of this fourth edition of Techniques in Extracorporeal Cirulation. The book continues to provide a comprehensive overview of the field, covering both established techniques for those new to the field of extracorporeal circulation, and current and future developments. It attempts to answer some of the innumerable practical problems associated with the routine use of artificial circulation and oxygenation, and hopes to stimulate thought and debate among its readers regarding more complex or controversial issues. Topics new to the fourth edition include robotic surgery and off-pump surgery, while other chapters have been thoroughly revised and updated to take into account developments and changes in the field. With its multidisciplinary approach, the book will remain an essential reference for all health care professionals working in the cardiac surgical operating room, in particular cardiothoracic surgeons, anaesthetists and perfusionists.
Thoroughly updated and tightly organized into a highly-condensed outline bulleted format, this handy, pocket-sized manual details precise, up-to-date information for diagnosis and treatment of lung cancer. Throughout Dx/Rx: Lung Cancer, Second Edition, tables and figures summarize important clinical data and current professional society recommendations, while salient references direct readers to additional information. Presented in an easy-to-read format, Dx/Rx: Lung Cancer, Second Edition is a must-have resource for oncologists, internists, primary care physicians, and other health care professionals on the ward or in the clinic.
This authored book's purpose is to extend and consolidate the evolving literature on multinational work teams by developing a comprehensive theory that incorporates a dynamic, multilevel view of such teams. The model used by the authors focuses on various features of the team's members, their interactions as a team, and the organizational context in which they operate. The concept of integration and differentiation, as well as the notion of equilibrium are used as a general force guiding the specific processes that link various levels of analysis in the model. Providing a framework for scholars and students in the field of organizational studies, this book presents: *a comprehensive review of the literature related to multinational and multicultural teams; *an overview of the specific model driving our thinking along with an extensive description of the component parts; *the individual and group-level elements of teams and their members; *the linking processes that connect various elements and structures; *the catalysts that give rise to changes in various elements and structures described in the theory section; and *a general integration of the model and an application of this framework for understanding MNT's in diverse cultural contexts.
This book explores how human civilization has contributed to changes in the Anthropocene, an era that marks a fundamental change in the way mankind has interacted with the Earth system. It examines the 21st century in the context of human development of water infrastructures, climate change impacts on freshwater resources, groundwater depletion, rising population, land use change, extreme events (droughts, floods, and wildfires). The implications of climate change impacts on environmental assets and the global water cycle are also highlighted. The book takes a pragmatically trans-disciplinary and holistic approach to the discussion of these issues, and the Earth system in the Anthropocene, drawing from a plethora of case studies. The capabilities of machine learning tools in satellite hydrology applications have been demonstrated as well as the feasibility of remote sensing data and innovative geospatial tools in environmental assessment. The book further showcases the multiple strengths and potential of new multi-disciplinary satellite radar programmes and geodetic missions, to measure and characterize extreme events, and their links to global climate, as well as in remote sensing of the environment. The aim is to provide innovative tools and a scientific framework that underpin our fundamental understanding of environmental systems, and the complexities of socio-hydrological systems in the Anthropocene. Policy issues have also been raised as an important aspect that can strengthen the management and administration of water resources, particularly in emerging economies where observational data is often lacking, limited, or difficult to access. It also highlights the lessons learned from freshwater hotspots (e.g., Lake Chad and Lake Urmia) where prolonged droughts and human activities have led to a permanent loss of surface water. It identifies the role of institutions and stakeholders in driving policies that underpins water management and climate change adaptation. The book articulates the novel applications of remote sensing tools as part of a monitoring framework that can alert stakeholders and the public sector to the dangers of mismanagement of freshwater in these hotspots and help facilitate water governance approaches. The book fills a critical gap in the multi-disciplinary aspect of planetary science, particularly in understanding the impacts of climate change and human actions on freshwater resources, as well as the stability of the Earth system.
This book highlights several opportunities that exist in satellite remote sensing of large-scale terrestrial hydrology. It lays bare the novel concept of remote sensing hydrology and demonstrates key applications of advance satellite technology and new methods in advancing our fundamental understanding of environmental systems. This includes, using state-of-the-art satellite hydrology missions like the Gravity Recovery and Climate Experiment and other multi-mission satellite systems as important tools that underpin water resources planning and accounting. This book discusses and demonstrates how the efficacy, simplicity, and sophistication in novel computing platforms for big earth observation data can help facilitate environmental monitoring and improve contemporary understanding of climate change impacts on freshwater resources. It also provides opportunities for practitioners and relevant government agencies to leverage satellite-based information in a transdisciplinary context to address several environmental issues affecting society. This book provides a general framework and highlights methods to help improve our understanding of hydrological processes and impact analysis from extreme events (e.g., droughts, floods) and climate change.
Climate change is one of the greatest threats facing humanity, a definitive manifestation of the well-worn links between progress and devastation. This book explores the complex relationship that the corporate world has with climate change and examines the central role of corporations in shaping political and social responses to the climate crisis. The principal message of the book is that despite the need for dramatic economic and political change, corporate capitalism continues to rely on the maintenance of 'business as usual'. The authors explore the different processes through which corporations engage with climate change. Key discussion points include climate change as business risk, corporate climate politics, the role of justification and compromise, and managerial identity and emotional reactions to climate change. Written for researchers and graduate students, this book moves beyond descriptive and normative approaches to provide a sociologically and critically informed theory of corporate responses to climate change.
Proton Transfer Reaction Mass Spectrometry (PTR-MS) is a rapidly growing analytical technique for detecting and identifying very small quantities of chemical compounds in air. It has seen widespread use in atmospheric monitoring and food science and shows increasing promise in applications such as industrial process monitoring, medical science and in crime and security scenarios. Written by leading researchers, this is the first book devoted to PTR-MS and it provides a comprehensive account of the basic principles, the experimental technique and various applications, thus making this book essential reading for researchers, technicians, postgraduate students and professionals in industry. The book contains nine chapters and is divided into two parts. The first part describes the underlying principles of the PTR-MS technique, including • the relevant ion-molecule chemistry • thermodynamics and reaction kinetics • a discussion of ion sources, drift tubes and mass spectrometers • practical aspects of PTR-MS, including calibration. The second part of the book turns its attention to some of the many applications of PTR-MS, demonstrating the scope and benefits, as well as the limitations, of the technique. The chapters that make up the second part of the book build upon the material presented in the first part and are essentially self-contained reviews focusing on the following topics: • environmental science • food science • medicine • homeland security, and • applications of PTR-MS in liquid analysis.
A Chronicle of Higher Education “Top 10 Books on Teaching” Selection Winner of the Virginia and Warren Stone Prize Constrained by shrinking budgets, can colleges do more to improve the quality of education? And can students get more out of college without paying higher tuition? Daniel Chambliss and Christopher Takacs conclude that the limited resources of colleges and students need not diminish the undergraduate experience. How College Works reveals the surprisingly decisive role that personal relationships play in determining a student's collegiate success, and puts forward a set of small, inexpensive interventions that yield substantial improvements in educational outcomes. “The book shares the narrative of the student experience, what happens to students as they move through their educations, all the way from arrival to graduation. This is an important distinction. [Chambliss and Takacs] do not try to measure what students have learned, but what it is like to live through college, and what those experiences mean both during the time at school, as well as going forward.” —John Warner, Inside Higher Ed
Five hundred years before Columbus, barbaric Viking invasions ravaged North America. Pathfinder is the story of a young Viking boy left behind as the only survivor of a shipwrecked expedition. A stranger in a strange land, the boy is raised by a tribe of American Indians - the very people the Vikings had sworn to destroy. When Vikings again storm the eastern shores, waging another barbaric campaign, they slaughter the tribe that adopted the young man. Now he wages a violent personal war to stop the Vikings' trail of death and destruction.
The Energy of Physics, Part I: Classical Mechanics and Thermodynamics provides students the opportunity to learn physics the way in which physicists understand the discipline. In contrast to standard textbooks, which introduce forces first, this text begins with classical mechanics using the concept of energy conservation. By inverting the standard order of presentation, the book enables students to understand and use calculus effectively, particularly toward applications in physics. Energy conservation is a constant theme throughout the text. Newton's laws are presented in terms of work and changes in kinetic energy, and forces are introduced as the derivative of potential energy, which is necessary for defining equilibrium conditions. A generalization of forces and Newton's laws then motivates the concepts of linear and angular momentum. The mode of presentation also allows thermodynamics to be incorporated throughout the text. The second edition includes a new chapter on fluids and new and additional practice problems for all chapters. The Energy of Physics, Part I gives students a better understanding of classical mechanics and provides a solid foundation for more advanced physics concepts and courses. The text is ideal for calculus-based physics courses for science and engineering majors. Christopher J. Fischer is an associate professor, the associate chair of the Department of Physics and Astronomy, and the director of the Engineering Physics Program at the University of Kansas, Lawrence. He holds a Ph.D. in applied physics from the University of Michigan, Ann Arbor. His research focuses on biophysics with an emphasis on understanding the function of molecular motors, especially those that manipulate DNA structure. He has been extensively involved in curriculum development at the University of Kansas, including the redesign of the introductory calculus-based physics sequence.
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