Plant research has stood at the forefront of the genomics revolution. One of the first genome projects, the sequencing of the commonly used model organism Arabidopsis, has already yielded important results for the study of a broad array of crops such as corn and soybeans. With crop and food bioengineering only in its infancy, the need to understand the fundamental genetic mechanisms of plants will only become more pressing. A comprehensive guide to this fascinating area of genomics, Plant Genomics and Proteomics presents an integrated, broadly accessible treatment of the complex relationship between the genome, transcriptome, and proteome of plants. This clearly written text introduces the reader to the range of molecular techniques applicable to investigating the unique facets of plant growth, development, and response to the environment. Coverage includes: Functional and structural genomics addressed within the context of current techniques and challenges to come How to utilize DNA and protein sequence data Practical considerations for choosing and employing the most commonly available computer applications A review of applications for biotechnology, including genetic modification and defense against pathogens Bioinformatics tools and Web resources Numerous examples from the latest research throughout Assuming no specialized knowledge of plant biology on the part of its reader, Plant Genomics and Proteomics provides an invaluable resource for students and researchers in biotechnology, plant biology, genomics, and bioinformatics.
When Augustus De Morgan died in 1871, he was described as ‘one of the profoundest mathematicians in the United Kingdom’ and even as ‘the greatest of our mathematicians’. But he was far more than just a mathematician. Because much of his voluminous written output on various subjects was scattered throughout journals and encyclopaedias, the breadth of his interests and contributions has been underappreciated by historians. Now, renewed interest in De Morgan’s life and work has coincided with the digitization of his extensive library, revealing the extent to which he pioneered and influenced the development of not merely mathematics but also logic, astronomy, the history of mathematics, education, and bibliography. This edited collection celebrates De Morgan as a polymath. Drawing together multiple elements of his activity from a range of publications and archives, its contributors re-assess his academic work, his place in his intellectual environment, and his legacy. The result offers new insight into De Morgan himself as well as the wider circles in which he moved, including his family life.
Infectious Diseases of the Fetus and Newborn Infant, written and edited by Drs. Remington, Klein, Wilson, Nizet, and Maldonado, remains the definitive source of information in this field. The 7th edition of this authoritative reference provides the most up-to-date and complete guidance on infections found in utero, during delivery, and in the neonatal period in both premature and term infants. Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization of the fetus/mother. Nationally and internationally recognized in immunology and infectious diseases, new associate editors Nizet and Maldonado bring new insight and fresh perspective to the book. Get the latest information on maternal infections when they are pertinent to the infant or developing fetus, including disease transmission through breastfeeding Diagnose, prevent, and treat neonatal infectious diseases with expert guidance from the world's leading authorities and evidence-based recommendations. Incorporate the latest findings about infections found in utero, during delivery, and in the neonatal period. Find the critical answers you need quickly and easily thanks to a consistent, highly user-friendly format Get fresh perspectives from two new associate editors—Drs. Yvonne Maldonado, head of the Pediatric Infectious Disease program at Stanford, and Victor Nizet, Professor of Pediatrics & Pharmacy at University of California, San Diego and UCSD School of Medicine. Keep up with the most relevant topics in fetal/neonatal infectious disease including new antimicrobial agents, gram- negative infections and their management, and recommendations for immunization of the fetus/mother. Overcome the clinical challenges in developing countries where access to proper medical care is limited. Apply the latest recommendations for H1N1 virus and vaccines. Identify and treat infections with the latest evidence-based information on fighting life-threatening diseases in the fetus and newborn infants.
Get the core knowledge in pain medicine you need from one of the most trusted resources in the field. The new fourth edition guides you through every aspect of pain medicine with concise descriptions of evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. From commonly seen pain syndromes, including headaches, trunk pain, orofacial pain, back pain, and extremity pain...through specific pain management challenges such as postoperative pain, pain due to cancer, phantom pain, and pain in the management of AIDS patients...this popular text will equip you with the know-how you need to effectively manage even your most challenging cases. A practical, multidisciplinary approach to pain management makes key concepts and techniques easier to apply to everyday practice. Expert contributors provide the latest knowledge on all aspects of pain management, from general principles through to specific management techniques. Detailed discussions of the latest concepts and treatment plans help you provide the best possible outcomes for all your patients. Extensively updated chapters acquaint you with the most current trends and techniques in pain management. A new section on complications helps you avoid and manage potential pitfalls. A new editorial team ensures that you are getting the freshest, most clinically relevant information available today. New, full-color art clarifies key concepts and techniques.
Gathering leading thinkers in social and clinical psychology, public health, medicine, and sociology, Interpersonal Relationships and Health considers theoretical and empirical issues relevant to understanding the social and clinical psychological mechanisms linking close relationship processes with mental and physical health outcomes. The volume arises out of a recent explosion of interest, across multiple academic and research fields, in the ways that interpersonal relationships affect health and well-being. This volume pulls together a range of scholars who focus on different aspects of relationships and health in order to encourage both collaboration and cross-disciplinary initiatives. This is the first edited volume to pull together noted experts across myriad disciplines whose research is at the intersection of human relationships and health. Topics addressed include key biological processes that influence and, in turn, are influenced by close relationships. Interpersonal Relationships and Health presents research that demonstrates the connections between interpersonal relationships, mental and physical health outcomes, and biophysical markers that figure prominently in the fields of psychoneuroimmunology, endocrinology, and cardiology. In addition, it highlights recent work on marital, family, and social relationships and their interplay with health and well-being. Chapters also address sexual health among young and older adults, as well as clinical intervention efforts that focus on the role of relational factors in influencing health. Each chapter highlights extant theoretical and empirical findings and suggests future avenues for research in this burgeoning area.
Extracorporeal circulation has become firmly established as an invaluable and routine adjunct to cardiac and vascular surgery. Since its introduction in 1953, the technique has evolved rapidly with advancing technology leading to improvements in and simplification of the equipment involved. Developments in the understanding and application of basic science have also had a huge impact as our understanding of the complex anatomy, biochemistry, pharmacology and pathophysiology of the heart continues to grow. It is these advances in both technology and science that form the basis of this fourth edition of Techniques in Extracorporeal Cirulation. The book continues to provide a comprehensive overview of the field, covering both established techniques for those new to the field of extracorporeal circulation, and current and future developments. It attempts to answer some of the innumerable practical problems associated with the routine use of artificial circulation and oxygenation, and hopes to stimulate thought and debate among its readers regarding more complex or controversial issues. Topics new to the fourth edition include robotic surgery and off-pump surgery, while other chapters have been thoroughly revised and updated to take into account developments and changes in the field. With its multidisciplinary approach, the book will remain an essential reference for all health care professionals working in the cardiac surgical operating room, in particular cardiothoracic surgeons, anaesthetists and perfusionists.
Tell me worldlings, underneath the sun, If greater falsehood ever has been done' The Jew of Malta, written around 1590, can present a challenge for modern audiences. Hugely popular in its day, the play swings wildly and rapidly in genre, from pointed satire, to bloody revenge tragedy, to melodrmatic intrigue, to dark farce and grotesque comedy. Although set in the Mediterranean island of Malta, the play evokes contemporary Elizabethan social tensions, especially the highly charged issue of London's much-resented community of resident merchant foreigners. Barabas, the enormously wealthy Jew of the play's title, appears initially victimized by Malta's Christian Governor, who quotes scripture to support the demand that Jews cede their wealth to pay Malta's tribute to the Turks. When he protests, Barabas is deprived of his wealth, his means of livelihood, and his house, which is converted to a nunnery. In response to this hypocritical extortion, Barabas launches a horrific (and sometimes hilarious) course of violence that goes well beyond revenge, using murderous tactics that include everything from deadly soup to poisoned flowers. The play's sometimes complex treatment of anti-Semitism and its relationship to Shakespeare's Merchant of Venice remain matters of continuing scholarly reflection. This student edition contains a lengthy Introduction with background on the author, date and sources, theme, critical interpretation and stage history, as well as a fully annotated version of the playtext in modern spelling. James R. Siemon is Professor of English at Boston University.
In 2004, the Government Accountability Office provided a report detailing approximately 200 government-based data-mining projects. While there is comfort in knowing that there are many effective systems, that comfort isn‘t worth much unless we can determine that these systems are being effectively and responsibly employed.Written by one of the most
A provocative and eye-opening study of the essential role the US military and the Central Intelligence Agency played in the advancement of communication studies during the Cold War era, now with a new introduction by Robert W. McChesney and a new preface by the author Since the mid-twentieth century, the great advances in our knowledge about the most effective methods of mass communication and persuasion have been visible in a wide range of professional fields, including journalism, marketing, public relations, interrogation, and public opinion studies. However, the birth of the modern science of mass communication had surprising and somewhat troubling midwives: the military and covert intelligence arms of the US government. In this fascinating study, author Christopher Simpson uses long-classified documents from the Pentagon, the CIA, and other national security agencies to demonstrate how this seemingly benign social science grew directly out of secret government-funded research into psychological warfare. It reveals that many of the most respected pioneers in the field of communication science were knowingly complicit in America’s Cold War efforts, regardless of their personal politics or individual moralities, and that their findings on mass communication were eventually employed for the purposes of propaganda, subversion, intimidation, and counterinsurgency. An important, thought-provoking work, Science of Coercion shines a blazing light into a hitherto remote and shadowy corner of Cold War history.
This volume in the Contemporary Military, Strategic, and Security Issues series presents a concise introduction to the evolution, key concepts, discourse, and future options for improved strategic communication in today's U.S. government. Strategic Communication: Origins, Concepts, and Current Debates is a groundbreaking study, the first book explicitly focused on strategic communication as it is currently used and discussed in the U.S. government. Written specifically for those who are new to strategic communication, this incisive book clarifies the definitional debate, explores the history of the term and its practice, and embraces a broad, practical definition. But that is only the beginning. Moving to the realities of the issue, author Christopher Paul reviews dozens of government reports on strategic communication and public diplomacy released since 2000, examining specific proposals related to improving strategic communication in the U.S. government and explaining the disagreements. Most important, he offers consensus and clarity for the way ahead, discussing how disparate elements of the government can be coordinated to master—and win—the "war of ideas" through fully integrated and synchronized communications and actions.
For three days in the fall of 1846, U.S. and Mexican soldiers fought fiercely in the picturesque city of Monterrey, turning the northern Mexican town, known for its towering mountains and luxurious gardens, into one of the nineteenth century's most gruesome battlefields. Led by Brigadier General Zachary Taylor, graduates of the U.S. Military Academy encountered a city almost perfectly protected by mountains, a river, and a vast plain. Monterrey's ideal defensive position inspired more than one U.S. soldier to call the city "a perfect Gibraltar." The first day of fighting was deadly for the Americans, especially the newly graduated West Point cadets. But they soon adjusted their tactics and began fighting building to building. Chris D. Dishman conveys in a vivid narrative the intensity and drama of the Battle of Monterrey, which marked the first time U.S. troops engaged in prolonged urban combat. Future Civil War generals and West Point graduates fought desperately alongside rough Texan, Mississippian, and Tennessean volunteers. General Taylor engineered one of the army's first wars of maneuver at Monterrey by sending the bulk of his troops against the weakest part of the city, and embedded press reporters wrote eyewitness accounts of the action for readers back in the States. Dishman interweaves descriptions of troop maneuvers and clashes between units using pistols and rifles with accounts of hand-to-hand combat involving edged weapons, stones, clubs, and bare hands. He brings regular soldiers and citizen volunteers to life in personal vignettes that draw on firsthand accounts from letters, diaries, and reports written by men on both sides. An epilogue carries the narrative thread to the conclusion of the war. Dishman has canvassed a wide range of Mexican and American sources and walked Monterrey's streets and battlefields. Accompanied by maps and period illustrations, this skillfully written history will interest scholars, history enthusiasts, and everyone who enjoys a true war story well told.
One of the North’s greatest generals—the Rock of Chickamauga Most Southerners in the U.S. Army resigned their commissions to join the Confederacy in 1861. But at least one son of a distinguished, slaveholding Virginia family remained loyal to the Union. George H. Thomas fought for the North and secured key victories at Chickamauga and Nashville. Thomas’s wartime experiences transformed him from a slaveholder to a defender of civil rights. Remembered as the “Rock of Chickamauga,” Thomas became one of the most prominent Union generals and was even considered for overall command of the Union Army in Virginia. Yet he has been eclipsed by such names as Grant, Sherman, and Sheridan. Offering vivid accounts of combat, Einolf depicts the fighting from Thomas’s perspective to allow a unique look at the real experience of decision making on the battlefield. He examines the general’s recurring confrontations with the Union high command to make a strong case for Thomas’s integrity and competence, even as he exposes Thomas’s shortcomings and poor decisions. The result is a more balanced, nuanced picture than has previously been available. Probing Thomas’s personal character, Einolf reveals how a son of the South could oppose the views of friends and family. George Thomas: Virginian for the Union offers a fresh appraisal of an important career and lends new insight into the inner conflicts of the Civil War.
Includes over 30 maps and Illustrations The Staff Ride Handbook for the Vicksburg Campaign, December 1862-July 1863, provides a systematic approach to the analysis of this key Civil War campaign. Part I describes the organization of the Union and Confederate Armies, detailing their weapons, tactics, and logistical, engineer, communications, and medical support. It also includes a description of the U.S. Navy elements that featured so prominently in the campaign. Part II consists of a campaign overview that establishes the context for the individual actions to be studied in the field. Part III consists of a suggested itinerary of sites to visit in order to obtain a concrete view of the campaign in its several phases. For each site, or “stand,” there is a set of travel directions, a discussion of the action that occurred there, and vignettes by participants in the campaign that further explain the action and which also allow the student to sense the human “face of battle.” Part IV provides practical information on conducting a Staff Ride in the Vicksburg area, including sources of assistance and logistical considerations. Appendix A outlines the order of battle for the significant actions in the campaign. Appendix B provides biographical sketches of key participants. Appendix C provides an overview of Medal of Honor conferral in the campaign. An annotated bibliography suggests sources for preliminary study.
The book, illustrated with case examples, identifies and makes explicit the often diverse values of those involved in healthcare commissioning, whether as commissioners, providers or users of services. It provides a skills base and other support processes for working with differences in values held by those engaged in making decisions.
Agathokles of Syracuse ruled large areas of Sicily and southern Italy between 317 and 289 BC. In this book, Christopher de Lisle argues that Agathokles was an important player in the Mediterranean world at a key moment in its history. Agathokles' career has important implications for our definition of the Hellenistic world and its relationship to both the western Mediterranean and earlier Greek history. However, he has tended not to feature in studies of the Hellenistic world or of ancient Sicily. In ancient discourse about him, in the coins he issued, in his interactions with the world around him, and in the way he ruled, Agathokles is simultaneously heir to a long tradition and actively engaged in his contemporary world. The failure to place Agathokles in both of these contexts up till now has contributed to the development of an excessively deep separation between the western and eastern Mediterranean and between the Classical and Hellenistic periods. This work - the first book-length study of Agathokles in English in over a century - places him in the context of both the earlier history of Sicily, and the developments in the eastern Mediterranean that mark the start of the Hellenistic era. The volume includes a narrative of his career, studies of his coinage and his representation in literary sources, and a series of explorations of important themes and regions.
The rise of environmentalism has been one of the more remarkable developments in the politics of western societies in recent decades. However, as environmental awareness has become more generalized, the forms of expression of environmental concern have changed. Established environmental movement organizations have become embedded in policy networks, but, in some countries, there has been a resurgence of environmental radicalism. New groups, adopting innovative tactics, have mounted spectacular and disruptive protests. These developments pose interesting questions for social scientists and policy-makers. Has the institutionalization of established environmental organizations demobilized their supporters and reduced them to a passive, credit-card waving 'conscience' constituency? Has direct participation in environmental protest become the specialized activity of smaller numbers of people? Has there been a decline in the total volume of environmental protest, or is it merely that the forms of protest have changed? Have the protest repertoires of established groups moderated over time, or have they been stimulated by the emergence of more radical groups to adopt more challenging tactics? Has environmental protest become more confrontational? Do protests employ different repertoires of action according to the issues at stake? How does the incidence of protest vary over time and from one country to another? Is there evidence of a Europeanization of either the issues or the forms of environmental protest? These are some of the questions this volume addresses. Based upon an analysis of the protest events reported in one quality newspaper in each of eight countries during the ten years 1988 to 1997, this is the first systematically comparative study of environmental protest in a representative cross-section of EU member states. It breaks entirely new ground in the study of environmental politics in Europe and is a major contribution to the study of protest events.
When the first edition of Pediatric Psychopharmacology published in 2002, it filled a void in child and adolescent psychiatry and quickly establishing itself as the definitive text-reference in pediatric psychopharmacology. While numerous short, clinically focused paperbacks have been published since then, no competitors with the scholarly breadth, depth, and luster of this volume have emerged. In the second edition, Christopher Kratochvil, MD, a highly respected expert in pediatric psychopharmacology, joins the outstanding editorial team led by Dr. Martin and Dr. Scahill. In the new edition, the editors streamline the flow of information to reflect the growth in scientific data since the first edition appeared. The overall structure of the book remains the same, with major sections on underlying biology; somatic interventions; assessment and treatment; and special considerations.
Master the latest version of Fedora and Red Hat Enterprise Linux with the step-by-step instructions and hands-on advice in Fedora 9 and Red Hat Enterprise Linux Bible. Learn key system administration skills like setting users and automating system tasks, understand the latest security issues and threats, and gain confidence with using and customizing the desktop menus, icons, and window manager. Updated every six months to correspond with the latest Fedora release, this book includes an official Fedora 9 LiveCD so that you can practice your knowledge and improve your skills. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.
Get all the essentials of the major changes in Fedora 14 Veteran authors Christopher Negus and Eric Foster-Johnson provide you with a thorough look at the skills needed to master the latest version of Fedora and Red Hat Linux. Their step-by-step instructions walk you through a painless and simple installation of Linux; then you'll explore the major changes to the release of Fedora 14 while also revisiting the previous version so you can see what features have been updated and revised. Focuses on the essentials of the updated and new elements of Fedora Linux 14 Addresses using packagekit, running Windows apps, scanning images, and installing over the Internet Touches on how to work in a Linux office with MSFT office compatible office apps Covers new material on zarafa, xenner, deja dup, and more Features a DVD that includes the latest distribution of Fedora Linux as well as a bootable Fedora LiveCD Fedora 14 includes many important updates and additions -- this book gets you up to date on the most essential changes.
For 40 years, Fischer’s Mastery of Surgery has provided expert, highly illustrated coverage of the procedures that general surgeons and trainees need to know. The fully revised eighth edition, under the editorial leadership of Drs. E. Christopher Ellison, Gilbert R. Upchurch Jr., Philip A. Efron, Steven D. Wexner, Nancy D. Perrier, V. Suzanne Klimberg, John H. Stewart IV, Valerie W. Rusch, Jon C. Gould, Susan Galandiuk, Timothy M. Pawlik, William C. Chapman, Benjamin K. Poulose, Peter K. Henke, Alicia M. Mohr, Saleem Islam, Anne M.R. Agur, Carol Scott-Conner, and David Renton continues the tradition of excellence with two full-color volumes that include the essentials of diagnosis, anatomy, and pre-operative planning while maintaining a focus on clear, step-by-step depictions and descriptions of procedures.
The Autisms, written by Mary Coleman and Christopher Gillberg, demonstrates that autism, like mental retardation, is a clinical presentation of numerous different diseases, many with genomic underpinnings. In this ground-breaking work, the authors explain in great detail how to clinically diagnose infants, children, adolescents and adults with autistic behavioral features and their psychiatric and neurological work-ups. This new edition contains several chapters on the associated problems of autism, such as intellectual disability, epilepsy, tics, eating disorders and sleep problems, as well as a chapter on epidemiology that documents the historical increase in autism diagnoses. Several chapters summarize the latest data on neuroanatomy, biochemistry and neuropsychology, while three neurogenomics chapters show evidence suggesting that autism occurs due to genetic errors which cause interruption or misdirection of critical neurodevelopmental circuits in the fetal brain. Completely up-to-date, The Autisms is relevant and necessary reading for researchers and clinicians in neuroscience, neurology, pediatrics, psychiatry, and psychology.
Obtain all the core knowledge in pain management you need from one of the most trusted resources in the field. The new edition of Practical Management of Pain gives you completely updated, multidisciplinary overview of every aspect of pain medicine, including evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. In print and online, it is all the expert guidance necessary to offer your patients the best possible relief. "In summary, this is the best explanation of what lies behind MRI that I have read, taking what can be a dry subject and making it readily understandable and really interesting. I would recommend it to anyone starting their MRI training and anyone trying to teach MRI to others." Reviewed by RAD Magazine, June 2015 Understand and apply the latest developments in pain medicine with brand-new chapters covering disability assessment, central post-stroke pain, chronic widespread pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics). Access up-to-the-minute knowledge on all aspects of pain management, from general principles to specific management techniques, with contributions from renowned experts in the field. Read the full text and view all the images online at expertconsult.com. Understand and apply the latest developments in pain management with brand-new chapters covering disability assessment, central post-stroke pain, widespread chronic pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics).
With comprehensive, highly visual coverage designed for sports clinicians, team physicians, sports medicine fellows, primary care physicians, and other health care professionals who provide care to athletes and active individuals, Netter's Sports Medicine, 3rd Edition, is an ideal resource for everyday use. Editors include three past presidents of the American Medical Society for Sports Medicine, it includes contributions from world-renowned experts as well as a rich illustration program with many classic paintings by Frank H. Netter, MD. From Little League to professional sports, weekend warriors to Olympic champions, and backcountry mountainside to the Super Bowl field, this interdisciplinary reference is indispensable in the busy outpatient office, in the training room, on the sidelines, and in preparation for sports medicine board certification. - More than 1,000 superb Netter graphics, tables, figures, pictures, diagnostic images, and other medical artwork highlight easy-to-read, bulleted text. - New coverage of esports, as well as other key topics such as travel considerations for the athlete, EKG interpretation, cardiac disease, diagnostic imaging and ultrasound, injury prevention protocols, and mixed martial arts. - Up-to-date information on nutritional supplements, eating disorders, sports and pharmacology for chronic conditions and behavioral medicine, and extreme and adventure sports. - Designed for quick reference, with a logical organization by both topic and sport. - Online features include downloadable patient education handouts, and handy links.
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