Examining the interdependent nature of substance, space, and subjectivity, this book constitutes an interdisciplinary analysis of the intoxication indigenous to what has been termed "our narcotic modernity." The first section – Drug/Culture – demonstrates how the body of the addict and the social body of the city are both inscribed by "controlled" substance. Positing addiction as a "pathology (out) of place" that is specific to the (late-)capitalist urban landscape, the second section – Dope/Sick – conducts a critique of the prevailing pathology paradigm of addiction, proposing in its place a theoretical reconceptualization of drug dependence in the terms of "p/re/in-scription." Remapping the successive stages or phases of our narcotic modernity, the third section – Narco/State – delineates three primary eras of narcotic modernity, including the contemporary city of "safe"/"supervised" consumption. Employing an experimental, "intra-textual" format, the fourth section – Brain/Disease – mimics the sense, state or scape of intoxication accompanying each permutation of narcotic modernity in the interchangeable terms of drug, dream and/or disease. Tracing the parallel evolution of "addiction," the (late-)capitalist cityscape, and the pathological project of modernity, the four parts of this book thus together constitute a users’ guide to urban space.
This book describes how the Jerne-Burnet Forbidden Clone Theory and the Adams-Knight H Gene Theory, solved the pathogenesis and genetics of the autoimmune diseases showing how specific immunotherapy and prophylaxis can be developed. Furthermore, Ebringer's discovery of two microbial triggers of autoimmune diseases is described and the conclusion drawn that all autoimmune diseases have microbial triggers, so will be preventable by the finding of the triggers and vaccination against them.
For more than 30 years, Practical Management of Pain has offered expert guidance to both clinicians and trainees, covering every aspect of acute and chronic pain medicine for adult and pediatric patients. The fully revised 6th Edition brings you fully up to date with new developments in patient evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. Edited by a team of renowned pain clinicians led by Dr. Honorio Benzon, this authoritative reference is a comprehensive, practical resource for pain diagnosis and treatment using a variety of pharmacologic and physical modalities. - Presents a wealth of information in a clearly written, easily accessible manner, enabling you to effectively assess and draw up an optimal treatment plan for patients with acute or chronic pain. - Takes a practical, multidisciplinary approach, making key concepts and techniques easier to apply to everyday practice. - Shares the knowledge and expertise of global contributors on all facets of pain management, from general principles to specific management techniques. - Discusses the latest, best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents such as topical analgesics. - Covers recent global developments regarding opioid induced hyperalgesia, neuromodulation and pain management, and identification of specific targets for molecular based pain. - Includes current information on the use of cannabinoids in pain management and related regulatory, professional, and legal considerations. - Includes the latest guidelines on facet injections and safety of contrast agents. - Provides new, evidence-based critical analysis on treatment modality outcomes and the latest information on chronic pain as a result of surgical interventions. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Infectious Diseases of the Fetus and Newborn Infant, written and edited by Drs. Remington, Klein, Wilson, Nizet, and Maldonado, remains the definitive source of information in this field. The 8th edition of this authoritative reference provides the most up-to-date and complete guidance on infections found in utero, during delivery, and in the neonatal period in both premature and term infants. Special attention is given to the prevention and treatment of these diseases found in developing countries as well as the latest findings about new antimicrobial agents, gram-negative infections and their management, and recommendations for immunization of the fetus/mother. Nationally and internationally recognized in immunology and infectious diseases, new associate editors Nizet and Maldonado bring new insight and fresh perspective to the book. Form a definitive diagnosis and create the best treatment plans possible using evidence-based recommendations and expert guidance from world authorities. Locate key content easily and identify clinical conditions quickly thanks to a consistent, highly user-friendly format now featuring a full-color design with hundreds of illustrations, and fresh perspectives from six new authoritative chapter lead authors. Explore what's changing in key areas such as: - emerging problems and concepts in maternal, fetal, and neonatal infectious diseases - anticipation and recognition of infections occurring in utero, during delivery, and in the neonatal period Stay on the cutting edge of your field with new and improved chapters including: obstetric factors associated with infections of the fetus and newborn infant; human milk; borella infections; tuberculosis; bordetella pertussis and other bordetella sp infections; herpes simplex; toxoplasmosis; pneumocystis and other less common fungal infections; and healthcare-associated infections in the nursery Keep up with the most relevant topics in fetal/neonatal infectious disease including new antimicrobial agents, gram- negative infections and their management, and recommendations for immunization of the fetus/mother. Overcome clinical challenges in developing countries where access to proper medical care is limited. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
Oxbow says: This fascinating study of how people understood and used their senses in the late medieval period draws on evidence from a range of literary texts, documents and records, as well as material culture and architectural sources.
Examining the interdependent nature of substance, space, and subjectivity, this book constitutes an interdisciplinary analysis of the intoxication indigenous to what has been termed "our narcotic modernity." The first section – Drug/Culture – demonstrates how the body of the addict and the social body of the city are both inscribed by "controlled" substance. Positing addiction as a "pathology (out) of place" that is specific to the (late-)capitalist urban landscape, the second section – Dope/Sick – conducts a critique of the prevailing pathology paradigm of addiction, proposing in its place a theoretical reconceptualization of drug dependence in the terms of "p/re/in-scription." Remapping the successive stages or phases of our narcotic modernity, the third section – Narco/State – delineates three primary eras of narcotic modernity, including the contemporary city of "safe"/"supervised" consumption. Employing an experimental, "intra-textual" format, the fourth section – Brain/Disease – mimics the sense, state or scape of intoxication accompanying each permutation of narcotic modernity in the interchangeable terms of drug, dream and/or disease. Tracing the parallel evolution of "addiction," the (late-)capitalist cityscape, and the pathological project of modernity, the four parts of this book thus together constitute a users’ guide to urban space.
How can you best persuade an appellate court to decide a case in your favor? This book is packed with useful examples and clever ancedotes that will sharpen your presentation and argument skills for use at the state, federal and Supreme Court level.
Molecular Biology of Cancer has been extensively revised and covers heredity cancer, microarray technology and increased study of childhood cancers. It continues to provide a detailed overview of the process which lead to the development and proliferation of cancer cells, including the techniques available for their study. It also describes the means by which tumor suppressor genes and oncogenes may be used in the diagnosis and in determining the prognosis of a wide variety of cancers, including breast, genitourinary, lung and gastrointestinal cancer.
A fascinating collection of original photographs of Highland Railway locomotives. Formed in 1865 the company was absorbed by the London Midland Scottish in the 1923 grouping of Britain's railways.
This lavishly illustrated operative atlas consists of detailed, step-by-step descriptions of the procedures used in reconstruction of the female urinary tract from the kidney to the urethra. It is based on the extensive operative experience of two very experienced reconstructive urologists. The procedures described have been devised compeletely afresh or considerably developed during the course of many thousands of operations and thus represent a unique collection. Many of the procedures and "tips" have not been published before. The approach taken throughout the book is a functional one. The basic principles underlying reconstrucive urology are outlined and emphasis is placed on the fact that the logic of each procedure is dictated by a thorough understanding of the particular functional abnormality involved. In addition there is a wealth of practical tips, observations and clinical pearls built up over many years of surgical experience which help to reduce complications and make operations easier. Each operative procedure is described by a sequence of colour photographs with running captions explaining the pitfalls and points of particular importance at each stage. It will be an indispensible guide to reconstructive urology for urologists and gynaecologists alike.
The essential guide to monitoring neural function during intricate neurosurgery procedures Intraoperative Neuromonitoring takes you step by step through the proper protocols for measuring and mapping neural function, emphasizing the correct application of intraoperative recordings for improved surgical outcomes. You will learn how to utilize the very latest neuromonitoring tools, and familiarize yourself with the full range of topics pertaining to intraoperative monitoring in neurosurgery. The authors also present both common and lesser-known techniques for neural assessment, resulting in a stand-alone reference that helps you master any type of neuromonitoring for virtually every kind of procedure. FEATURES: The most complete, expert-authored intraoperative neuromonitoring resource available, addressing the most current topics, tools, and techniques to enhance your skills Valuable, learn-as-you-go guidance on measuring and mapping neural structures focuses on the proper evaluation of pertinent patient data and providing the surgeon with accurate updates through the duration of the case Logical five-part organization clearly explains must-know topics such as neuromonitoring during cerebrovascular surgery, mapping cerebral and brainstem function, neuromonitoring in spinal surgery peripheral nerve procedures,and more Numerous illustrations, figures, surgical images, and angiograms Full chapter-ending references provide opportunities for further study and research
A unique combination text and atlas gives you expert guidance on facial reconstruction DVD with video of 35 procedures Facial Flap Surgery delivers ready-to-use insights making surgical protocols more accessible than ever. Combining a text and atlas, this two-in-one resource also features an all-inclusive, yet streamlined presentation that is packed with hundreds of photographs and drawings that take you step by step through every procedure. Facial Flap Surgery begins with an incisive review of the bioanatomy and mechanics of tissue movement, highlighting how to mobilize soft tissue to reconstruct cutaneous operative wounds. Next is an unsurpassed overview of all flap types, including some never published before: from advancement flaps to rotation and banner flaps. Another section examines the repair of specific facial features, including the nose, ear, lip, and temple. Last, complications such as hematomas and flap failure are covered, helping you achieve the best possible outcomes. FEATURES Illuminates the biomechanical properties and need-to-know subtypes of each flap category An atlas of real-life cases that aids you in determining which type of flap will provide optimal surgical outcomes for any patient In-depth chapters explain how to effectively utilize each of the flaps in surgeries for specific facial regions Companion DVD filled with 35 video clips offers an unmatched tutorial that takes you through the preparation and successful use of facial flaps in multiple facial regions
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