[2.2]Paracyclophane is a prevalent π‐stacked, carbocyclic scaffold with a “bent and battered” structure. This results not only in a transannular communication but also in a chiral plane within the molecule if at least one substituent is present. These unique properties make this structure synthetically challenging but also scarcely investigated. A new method for enantio-separation based on the kinetic resolution was developed, which allows the access to enantiomerically pure [2.2]paracyclophane-based building blocks. In a liquid crystal templated chemical vapor deposition process, [2.2]paracyclophanyl alcohols containing an additional central chiral element were evaluated for the self-assembly of nanofibers. Furthermore, the cyclopropanation of α-alkyl-α-diazo compounds with a [2.2]paracyclophane-based rhodium tetracarboxylate complex was investigated. Finally, the rigidity, regioselective functionalization, and transannular communication of [2.2]paracyclophane were exploited in the design of heterobimetallic gold/ruthenium complexes for the study of metal-to-metal interactions.
Now available in paperback, this landmark biography was first published in 2000 to mark the 250th anniversary of J. S. Bach's death. Written by a leading Bach scholar, this book presents a new picture of the composer. Christoph Wolff demonstrates the intimate connection between Bach's life and his music, showing how the composer's superb inventiveness pervaded his career as a musician, composer, performer, scholar, and teacher.
When David Gorlaeus (1591-1612) passed away at 21 years of age, he left behind two highly innovative manuscripts. Once they were published, his work had a remarkable impact on the evolution of seventeenth-century thought. However, as his identity was unknown, divergent interpretations of their meaning quickly sprang up. Seventeenth-century readers understood him as an anti-Aristotelian thinker and as a precursor of Descartes. Twentieth-century historians depicted him as an atomist, natural scientist and even as a chemist. And yet, when Gorlaeus died, he was a beginning student in theology. His thought must in fact be placed at the intersection between philosophy, the nascent natural sciences, and theology. The aim of this book is to shed light on Gorlaeus’ family circumstances, his education at Franeker and Leiden, and on the virulent Arminian crisis which provided the context within which his work was written. It also attempts to define Gorlaeus’ place in the history of Dutch philosophy and to assess the influence that it exercised in the evolution of philosophy and science, and notably in early Cartesian circles. Christoph Lüthy is professor of the history of philosophy and science at Radboud University Nijmegen, the Netherlands.
This book investigates the powerful role of online intermediaries, which connect companies with their end customers, to facilitate joint product innovation. Especially in the healthcare context, such intermediaries deploy interactive online platforms to foster co-creation between engaged healthcare consumers and innovation-seeking healthcare companies. In three empirical studies, this book outlines the key characteristics of online intermediaries in healthcare, their distinct strategies, and the remaining challenges in the field. Readers will also be introduced to the stages companies go through in adopting such co-created solutions. As such, the work appeals for both its academic scope and practical reach.
[2.2]Paracyclophane is a prevalent π‐stacked, carbocyclic scaffold with a “bent and battered” structure. This results not only in a transannular communication but also in a chiral plane within the molecule if at least one substituent is present. These unique properties make this structure synthetically challenging but also scarcely investigated. A new method for enantio-separation based on the kinetic resolution was developed, which allows the access to enantiomerically pure [2.2]paracyclophane-based building blocks. In a liquid crystal templated chemical vapor deposition process, [2.2]paracyclophanyl alcohols containing an additional central chiral element were evaluated for the self-assembly of nanofibers. Furthermore, the cyclopropanation of α-alkyl-α-diazo compounds with a [2.2]paracyclophane-based rhodium tetracarboxylate complex was investigated. Finally, the rigidity, regioselective functionalization, and transannular communication of [2.2]paracyclophane were exploited in the design of heterobimetallic gold/ruthenium complexes for the study of metal-to-metal interactions.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.