A Fire Burns Within is the compelling tale of an all-time boxing great who fought his way to stardom from the mean streets of the Puerto Rican capital San Juan. Wilfredo 'Bazooka' Gomez discovered his love of boxing as he learned the noble art to help him fight off bullies as he walked the streets of the capital. Showing great promise in the ring, he soon rose to prominence, and in the late 1970s and early 1980s set a blistering pace that many boxers wanted to emulate - but few could equal. The three-time world title winner is best remembered for his 17 consecutive title fight defences - but his story as a man and fighter runs much deeper. Including interviews with Gomez, those close to him, the fighters he fought and those who watched his remarkable career unfold, A Fire Burns Within reviews one of the finest boxing careers. It details Gomez's dramatic rise to fame, but also tells the largely untold story of the struggles he faced after his fight career ended, and how his mettle was tested in a completely different way.
This book deals with the city of Rome and its buildings in the period between Bernini's death in 1680 and the year 1797, when Thorvaldsen came to the papal city. It focuses on dealing mainly with some types of architectural monuments—such as monasteries, public civic buildings and town houses.
Stipulare un contratto con una controparte estera può far sorgere dubbi e problemi più complessi ed articolati rispetto a quelli generati dai rapporti contrattuali con soggetti nazionali. Il contesto in cui si sviluppa una transazione con l'estero è, infatti, caratterizzato dalla diversità di sistemi giuridici, dalla diversità di norme, di consuetudini, di significato attribuito a termini di uso comune che suggeriscono un esame attento delle diverse clausole contrattuali per ricercare quelle più idonee. Le componenti valutarie, finanziarie, creditizie, logistiche e commerciali, gli usi e le consuetudini, la scelta dei termini di consegna delle merci, le forme di pagamento in uso nei singoli Paesi possono, infatti, incidere in misura rilevante nella determinazione della natura e del contenuto del rapporto contrattuale. Nel volume sono approfondite le normative che interessano l'operatore italiano impegnato nel recupero di somme di denaro all'estero. Si esaminano il quadro normativo in vigore nell'Unione Europea, le norme italiane di diritto internazionale privato e processuale nonché le principali disposizioni di diritto uniforme relative alla vendita di beni mobili previste dalla Convenzione di Vienna. Si analizzano poi le disposizioni in essere in alcuni principali Paesi del mondo, ossia gli USA, la Cina, il Brasile, l'India, la Turchia e la Russia. STRUTTURA DEL VOLUME CAPITOLO 1 - Normativa comunitaria CAPITOLO 2 - La Convenzione di Vienna e la tutela contrattuale della parte venditrice CAPITOLO 3 - Il diritto internazionale privato italiano CAPITOLO 4 - Il recupero dei crediti negli Stati Uniti CAPITOLO 5 - Il recupero dei crediti in Cina CAPITOLO 6 - Il recupero dei crediti in Brasile CAPITOLO 7 - Il recupero dei crediti in India CAPITOLO 8 - Il recupero dei crediti in Turchia CAPITOLO 9 - Il recupero dei crediti in Russia Appendice
Great Myths of the Brain introduces readers to the field of neuroscience by examining popular myths about the human brain. Explores commonly-held myths of the brain through the lens of scientific research, backing up claims with studies and other evidence from the literature Looks at enduring myths such as “Do we only use 10% of our brain?”, “Pregnant women lose their mind”, “Right-brained people are more creative” and many more. Delves into myths relating to specific brain disorders, including epilepsy, autism, dementia, and others Written engagingly and accessibly for students and lay readers alike, providing a unique introduction to the study of the brain Teaches readers how to spot neuro hype and neuro-nonsense claims in the media
It is well known that estrogen is "somehow” a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen’s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer’s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women. Besides up-to-date information on estrogen and the brain, this book explains in a highly understandable manner molecular and cellular techniques by which basic data have been collected. The reader, which may include the professional specialist as well as the interested non-specialist, will also gain insight into the scientific transfer process of knowledge from basic science to the clinical situation and therefore "from bench to bed”.
This powerful new book provides a clear framework for understanding and learning an emerging management practice, leading public design. Drawing on more than a decade of work on public sector innovation, Christian Bason uses his extensive practical experience and research conducted among public managers in the UK, the US, Australia, Finland and Denmark to explore how public organisations can be redesigned from the outside in, shaping policies and services that are truly experienced as useful and meaningful to citizens, and which leverage all of society’s resources to co-produce better outcomes. Through detailed case studies, the book presents six management practices which leaders in government can use to involve citizens, staff and other stakeholders in innovation processes. It shows how managers can challenge their own assumptions, leverage empathy with citizens, handle divergence, navigate unknown territory, experiment and rehearse future solutions through prototyping, and create more public value. Ultimately, Leading public design provides a pathway to a new and different way of governing public institutions: human-centred governance. As a more relational, networked, interactive and reflective approach to running organisations, this emerging governance model promises a more human yet effective public sector.
Far from being simply a sequence of techniques, as practised in many countries osteopathy is an independent primary health care system based on principles applied through a manual practice: a unique profession that takes care of the whole person through the application of five models (biomechanical, neurological, respiratory-circulatory, metabolic, and behavioral). These conceptual models of the relationship between structure and function allow osteopaths to evaluate treatment with the aim of promoting health rather than curing disease. This book is intended as a manual for both students and osteopathic professionals interested in exploring the principles, objectives, origins and application of the five osteopathic models, from traditional concepts up to a modern vision, based on evidence and critical thinking. The selection criteria and rules for the application of each model, with their limitations and potential, are examined, to enable the reader to understand the rationale behind their use in a comprehensive, holistic and patient-centered practice.
This book presents the story of a unique collection of 140 manuscripts of ‘learned magic’ that was sold for a fantastic sum within the clandestine channels of the German book trade in the early eighteenth century. The book will interpret this collection from two angles – as an artefact of the early modern book market as well as the longue-durée tradition of Western learned magic –, thus taking a new stance towards scribal texts that are often regarded as eccentric, peripheral, or marginal. The study is structured by the apparent exceptionality, scarcity, and illegality of the collection, and provides chapters on clandestine activities in European book markets, questions of censorship regimes and efficiency, the use of manuscripts in an age of print, and the history of learned magic in early modern Europe. As the collection has survived till this day in Leipzig University Library, the book provides a critical edition of the 1710 selling catalogue, which includes a brief content analysis of all extant manuscripts. The study will be of interest to scholars and students from a variety of fields, such as early modern book history, the history of magic, cultural history, the sociology of religion, or the study of Western esotericism.
Business Purpose Design is an essential guide for a human-centric and holistic purpose for businesses. Discontinuity, uncertainty, complexity, and ambiguity are driving forces of our world. Entire markets, industries, departments, and specialist areas interact and correlate with each other - unplanned and open-ended. In our world, orientation and a common driver is key to navigate, to distinguish relevant information from irrelevant, to take decisions and lead companies to create a positive future. Together with 32 outstanding personalities, from thought leaders, executives, founders, designers, and scientists, Monika looks at the 30 most relevant topics für purpose entrepreneurship. Bonus: Many examples, trend outlooks, and conceptional images inspire new thoughts and ideas - and reassure existing developments. Furthermore, takeaways for every topic offer a hands-on guide to act right away. With the Business Purpose Design model, organizations of any size can design, build, and grow their business towards becoming impact-driven. It provides a toolkit, and over 90 practical tips to design or and implement purpose within an organization right away. It allows for many perspectives. Co-created by over 32 practitioners from 30 disciplines. Illustrated with a critical eye by one of Europe's most sophisticated graphic-recording duo. Specially designed for executives, consultants, entrepreneurs, coaches, managers, designers and leaders of all types of organizations. www.business-purpose.com
Building information modelling (BIM) uses a combination of technologies and resources to capture, manage, analyse, and display a digital representation of the physical and functional characteristics of a facility. A Geographic Information System (GIS) offers tools for visualising and analysing built and natural environments and their impacts on infrastructure systems, such as land use, transportation, etc. This book offers a framework for how the geospatial and surveying industry can create and integrate BIM with GIS. Through practical implementation methods, readers will learn to merge GIS data with design and BIM data to enable digital twins. This book presents the following features: Integrates BIM and GIS from a geospatial and surveying point of view for the first time; Addresses the creation of BIM from existing constructed buildings instead of typical pre-construction scenarios; Explains how to deliver BIM-suitable surveys to surveyors and geospatial practitioners; Provides surveying and geospatial industry expertise in the collecting, locating, managing, and communicating of BIM; Introduces new knowledge on the validation and integration of BIM and GIS within the spatial industry. This is an excellent book for professionals working with 3D data for built-environment digital twins, such as city planners, land surveyors, and geospatial practitioners. It is also an insightful resource for those working and studying in the fields of GIS, surveying, and geospatial engineering, providing the most current tools and resources for dealing with BIM.
This authoritative book offers a complete breakdown of the EUês political economy in the wake of the global financial crisis and will therefore appeal to students of European politics, international political economy and European studies, as well as po
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Variability in pathogenesis and complex pathophysiology often delay diagnosis and create significant challenges for clinical studies in this group of critically ill patients. Mainly for those reasons, there is no therapy approved so far to overcome the underlying immune dysregulation. This book provides an overview about the state of the art of sepsis diagnostics and potential future therapies. Chapter 1 focuses on the immunologic staging of sepsis—the key for successful treatment of the dysregulated hot response. Chapter 2 reveals similarities in the immune response in sepsis and cancer—opening new avenues for novel therapies. Chapter 3 introduces an important modulator of the immune response—the endogenous cannabinoid system and elucidates its role in organ dysfunction in sepsis. Facing the increasing bacterial resistance to classical antibiotics, Chapter 4 discusses two unique mechanisms to treat infection and inflammation in sepsis: iron chelation, and the sphingosine pathway. The authors, all experts in experimental and clinical sepsis research, seek to provide further understanding of the complexities of the immune response as the physiological basis for the development of new therapeutics in sepsis.
Structured around sexual desire as the central analytical category, this monograph systematically approaches a heterogeneous array of artworks to purposefully examine the entanglements of art, feminist theory, gender, and sexuality. This book considers the potential of sexually explicit art to challenge a socially constructed conception of sexuality as well as gender, and explores the sexually explicit as a means to (re-)claim agency for marginalized subjectivities and to emancipate desire from within the patriarchal and heteronormative system. In distinct case studies, the author focuses on works by four US-American artists – Robert Mapplethorpe, Joan Semmel, Betty Tompkins, and Tee A. Corinne – and situates them in relation to contemporaneous debates associated with the insurgent Sexual Liberation Movements of the 1970s. The book will be of interest to scholars working in art history, visual culture, and gender and sexuality studies.
Disassembly is one of the key elements of any processing of recovered products. Be it for repair, remanufacturing, refurbishing, cannibalisation, material recycling, or disposal. Hence, planning the disassembly is important and—with growing amounts of recovered products and need for saving resources—becomes even more important. The disassembly planning approaches presented are based on mathematical programming. With this methodology, a profit-optimal planning of quantities of multiple types of recovered products as well as parts distribution, material recycling, and disposal quantities is realised. Thereby,typical aspects, like material purity requirements, the condition of the recovered products, hazardous parts, and capacity limitations, are also considered. A new approach is the presented combination of disassembly-to-order planning and disassembly sequencing, which is called Flexible Disassembly Planning.
This thesis explores the idea that the Higgs boson of the Standard Model and the cosmological inflation are just two manifestations of one and the same scalar field - the Higgs-inflation. By this unification two energy scales that are separated by many orders of magnitude are connected, thereby building a bridge between particle physics and cosmology. An essential ingredient for making this model consistent with observational data is a strong non-minimal coupling to gravity. Predictions for the value of the Higgs mass as well as for cosmological parameters are derived, and can be tested by future experiments. The results become especially exciting in the light of the recently announced discovery of the Higgs boson. The model of non-minimal Higgs inflation is also used in a quantum cosmological context to predict initial conditions for inflation. These results can in turn be tested by the detection of primordial gravitational waves. The presentation includes all introductory material about cosmology and the Standard Model that is essential for the further understanding. It also provides an introduction to the mathematical methods used to calculate the effective action by heat kernel methods.
With its focus on drugs so recently introduced that they have yet to be found in any other textbooks or general references, the information and insight found here makes this a genuinely unique handbook and reference. Following the successful approach of the previous volumes in the series, inventors and primary developers of successful drugs from both industry and academia tell the story of the drug's discovery and describe the sometimes twisted route from the first drug candidate molecule to the final marketed drug. The 11 case studies selected describe recent drugs ranging across many therapeutic fields and provide a representative cross-section of present-day drug developments. Backed by plenty of data and chemical information, the insight and experience of today's top drug creators makes this one of the most useful training manuals that a junior medicinal chemist may hope to find. The International Union of Pure and Applied Chemistry has endorsed and sponsored this project because of its high educational merit.
This book focuses on the role of the endocannabinoid system in local and systemic inflammation, with individual chapters written by experts in the field of cannabinoid research and medicine. The topics explore the actions of the endocannabinoid system on the immune system, including neuroinflammation in autoimmune disorders such as multiple sclerosis, and in neurodegenerative disorders such as Huntington's and Alzheimer's, as well as local and systemic inflammatory conditions affecting organs including the eye (uveitis and corneal inflammation), the bladder (interstitial cystitis), pancreas (diabetes), cardiovascular system (stroke), joints (arthritis), and sepsis. The objective of this book is to provide knowledge transfer on the use of cannabinoids in inflammatory disease by critically examining preclinical and clinical research on the immunomodulatory actions of the endocannabinoid system, with specific emphasis on the actions of cannabinoids in diseases where inflammation is a prominent component. By drawing these results together, we seek to provide further understanding of the complexities of endocannabinoid system modulation of immune function and identify potential uses and limitations for cannabinoid-based therapeutics.
In European law, "non-contractual liability arising out of damage caused to another" is one of the three main non-contractual obligations dealt with in the Draft of a Common Frame of Reference. The law of non-contractual liability arising out of damage caused to another - in the common law known as tort law or the law of torts, but in most other jurisdictions referred to as the law of delict - is the area of law which determines whether one who has suffered a damage, can on that account demand reparation - in money or in kind - from another with whom there may be no other legal connection than the causation of damage itself. Besides determining the scope and extent of responsibility for dangers of one's own or another's creation, this field of law serves to protect fundamental rights in the private law domain, that is to say horizontally between citizens inter se. Based on pan-European comparative research which annotates the work, this book presents model rules on liability. Explanatory comments and illustrations amplify the policy decisions involved. During the drafting process, comparative material from over 25 different EU jurisdictions has been taken into account. The work therefore is not only a presentation of a future model for European rules to come, but also provides a fairly detailed indication of the present legal situation in the Member States.
The "European Yearbook" promotes the scientific study of nineteen European supranational organisations and the Organisation for Economic Co-operation and Development (OECD). Each volume contains a detailed survey of the history, structure and yearly activities of each organisation and an up-to-date chart providing a clear overview of the member states of each organisation. In addition, a number of articles on topics of general interest are included in each volume. A general index by subject and name, and a cumulative index of all the articles which have appeared in the "Yearbook," are included in every volume and provide direct access to the "Yearbook"'s subject matter. Each volume contains a comprehensive bibliography covering the year's relevant publications. This is an indispensable work of reference for anyone dealing with the European institutions.
This book provides an introduction to dynamical systems with multiple time scales. The approach it takes is to provide an overview of key areas, particularly topics that are less available in the introductory form. The broad range of topics included makes it accessible for students and researchers new to the field to gain a quick and thorough overview. The first of its kind, this book merges a wide variety of different mathematical techniques into a more unified framework. The book is highly illustrated with many examples and exercises and an extensive bibliography. The target audience of this book are senior undergraduates, graduate students as well as researchers interested in using the multiple time scale dynamics theory in nonlinear science, either from a theoretical or a mathematical modeling perspective.
Christian Giudice's Occult Imperium explores Italian national forms of Occultism, chiefly analyzing Arturo Reghini (1878-1946), his copious writings, and Roman Traditionalism. Trained as a mathematician at the prestigious University of Pisa, Reghini was one of the three giants of occult and esoteric thought in Italy, alongside his colleagues Julius Evola (1898-1974) and Giulian Kremmerz (1861-1930). Using Reghini's articles, books, and letters, as a guide, Giudice explores the interaction between occultism, Traditionalism, and different facets of modernity in early-twentieth-century Italy. The book takes into consideration many factors particular to the Italian peninsula: the ties with avant-garde movements such as the Florentine Scapigliatura and Futurism, the occult vogues typical to Italy, the rise to power of Benito Mussolini and Fascism, and, lastly, the power of the Holy See over different expressions of spirituality. Occult Imperium explores the convergence of new forms of spirituality in early twentieth-century Italy.
The EC Consumer Law Compendium presents the results of a wide-ranging study prepared for the European Commisison. This Compendium provides the reader with the necessary information for conducting pan-European cross-border consumer transactions. For the first time, the transposition of 8 key consumer directives (including those on sales, unfair terms, distance and doorstep selling as well as package travel and timeshare) into the national laws of all Member States is analyzed. The findings of this study reveal the substantial differences between the various national implementing measures as a result of utilising minimum harmonisation clauses and regulatory options.
This book accompanies you on a journey that starts with the basics of mine water treatment and takes you further through correct sampling for planning to active and passive systems. In the respective chapters you will learn the most important techniques about the parameters to be measured (e.g. on-site parameters, flow rate), which methods are available to actively treat your mine water (e.g. high density sludge method, reverse osmosis, ion exchange) and which ones to perform passive treatment (e.g. constructed wetlands, vertical flow reactor, limestone channel). You will also get an insight into the use of mine water. Don’t expect a cookbook – rather, it’s an ingredients and utensils list to help you find the right recipe. For extended help on this, check out the more than 1000 references on all the techniques presented. I wrote this book for hydrogeologists, engineers, graduate students, government officials, miners, geoecologists, chemical engineers – in the broadest sense: you. This book is a translation of an original German edition. The translation was done with the help of artificial intelligence (machine translation by the service DeepL.com). A subsequent human revision and a thorough copy editing and update by the author ensured that the contents are correctly represented.
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