During forty years of caring for districts of churches and isolated believers, besides raising up new churches by evangelistic effort, the author of this work became greatly impressed with the need of educating the people in the fundamental doctrines of the Holy Scriptures. He has found very few who could give from the word of God an intelligent reason for even its most prominent and important truths. This spiritual poverty any minister will discover by personal investigation. When we add to this condition the fact that during the past thirty years new errors have been stealthily introduced among Christians generally--errors which undermine the very foundations of Bible truth and Christianity--it becomes evident that even professing Christians are unprepared for the crises they will be obliged to meet in the near future.
During forty years of caring for districts of churches and isolated believers, besides raising up new churches by evangelistic effort, the author of this work became greatly impressed with the need of educating the people in the fundamental doctrines of the Holy Scriptures. He has found very few who could give from the word of God an intelligent reason for even its most prominent and important truths. This spiritual poverty any minister will discover by personal investigation. When we add to this condition the fact that during the past thirty years new errors have been stealthily introduced among Christians generally--errors which undermine the very foundations of Bible truth and Christianity--it becomes evident that even professing Christians are unprepared for the crises they will be obliged to meet in the near future.
This textbook provides a fresh, comprehensive and accessible introduction to the rapidly expanding field of molecular pharmacology. Adopting a drug target-based, rather than the traditional organ/system based, approach this innovative guide reflects the current advances and research trend towards molecular based drug design, derived from a detailed understanding of chemical responses in the body. Drugs are then tailored to fit a treatment profile, rather than the traditional method of ‘trial and error’ drug discovery which focuses on testing chemicals on animals or cell cultures and matching their effects to treatments. Providing an invaluable resource for advanced under-graduate and MSc/PhD students, new researchers to the field and practitioners for continuing professional development, Molecular Pharmacology explores; recent advances and developments in the four major human drug target families (G-protein coupled receptors, ion channels, nuclear receptors and transporters), cloning of drug targets, transgenic animal technology, gene therapy, pharmacogenomics and looks at the role of calcium in the cell. Current - focuses on cutting edge techniques and approaches, including new methods to quantify biological activities in different systems and ways to interpret and understand pharmacological data. Cutting Edge - highlights advances in pharmacogenomics and explores how an individual’s genetic makeup influences their response to therapeutic drugs and the potential for harmful side effects. Applied - includes numerous, real-world examples and a detailed case-study based chapter which looks at current and possible future treatment strategies for cystic fibrosis. This case study considers the relative merits of both drug therapy for specific classes of mutation and gene therapy to correct the underlying defect. Accessible - contains a comprehensive glossary, suggestions for further reading at the end of each chapter and an associated website that provides a complete set of figures from within the book.
The most comprehensive guide to the botany, history, distribution, and cultivation of all known psychoactive plants • Examines 414 psychoactive plants and related substances • Explores how using psychoactive plants in a culturally sanctioned context can produce important insights into the nature of reality • Contains 797 color photographs and 645 black-and-white illustrations In the traditions of every culture, plants have been highly valued for their nourishing, healing, and transformative properties. The most powerful plants--those known to transport the human mind into other dimensions of consciousness--have traditionally been regarded as sacred. In The Encyclopedia of Psychoactive Plants Christian Rätsch details the botany, history, distribution, cultivation, and preparation and dosage of more than 400 psychoactive plants. He discusses their ritual and medicinal usage, cultural artifacts made from these plants, and works of art that either represent or have been inspired by them. The author begins with 168 of the most well-known psychoactives--such as cannabis, datura, and papaver--then presents 133 lesser known substances as well as additional plants known as “legal highs,” plants known only from mythological contexts and literature, and plant products that include substances such as ayahuasca, incense, and soma. The text is lavishly illustrated with 797 color photographs--many of which are from the author’s extensive fieldwork around the world--showing the people, ceremonies, and art related to the ritual use of the world’s sacred psychoactives.
The penultimate instalment in the Chivalry series from a master of historical fiction. The Chivalry series follows young William Gold, who runs away from London to follow the Black Prince, from the killing fields of France, through life as a routier and criminal, and to redemption with the Knights of Saint John, further disillusion and an eventual career as a professional soldier and knight. Rich in the details of life in the High Middle Ages, the series also deals with modern issues about the role of violence in society, rules of conflict and war, and the price that people pay for using violence. 'One of the finest historical fiction writers in the world' BEN KANE 'The master of historical fiction' SUNDAY TIMES 'A storyteller at the height of his powers' HISTORICAL NOVEL SOCIETY
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