The classification of brain tumors has evolved from a morphological and histological basis to one that is now in keeping with the advances of modern technology consisting of novel molecular subgroups rooted in clinical outcome and risk stratification. In this chapter, we discuss recent and emerging genomic findings that may be of clinical utility in the foreseeable future for adult and pediatric glioblastoma, pediatric medulloblastoma, ependymoma, and diffuse intrinsic pontine glioma. Moreover, limitations in the current molecular classification of these tumors are discussed with the brain tumor-initiating cell and cancer stem cell model as frameworks for future research efforts in identifying novel genomic alterations for better discerning the intratumoral heterogeneous landscape of these solid tumors as an avenue for developing tumor subgroup-specific targeted therapy.
This book concisely provides important Pathology concepts to aid pathology trainees, including medical students and resident physicians, in passing any advanced pathology examination. It provides a much needed revision aid and study guide. Through dedicated questions and answers over 23 chapters covering every major organ system, the book will develop skills needed to deal with different aspects of pathology in a systematic yet summarized manner. The book helps solve problems faced by trainees by providing the highest yield content. Throughout the book, an intuitive and systematic approach is used to reinforce fundamental concepts.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.