The responses of offshore structures are significantly affected by steep nonlinear waves, currents and wind, leading to phenomena such as springing and ringing of TLPs, slow drift yaw motion of FPSOs and large oscillations of Spar platforms due to vortex shedding. Research has brought about significant progress in this field over the past few decades and introduced us to increasingly involved concepts and their diverse applicability. Thus, an in-depth understanding of steep nonlinear waves and their effects on the responses of offshore structures is essential for safe and effective designs.This book deals with analyses of nonlinear problems encountered in the design of offshore structures, as well as those that are of immediate practical interest to ocean engineers and designers. It presents conclusions drawn from recent research pertinent to nonlinear waves and their effects on the responses of offshore structures. Theories, observations and analyses of laboratory and field experiments are expounded such that the nonlinear effects can be clearly visualized.
In the past decade we have witnessed the birth and maturing of a field of research centering on the Ca2+ signaling functions of cyclic ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP), which structures and mechanisms of action are truly unique among all Ca2+ messengers. A wide range of physiological functions are now known to be mediated by them in cells spanning three biological kingdoms from protist, plant to animal. This is the first book devoted entirely to the field. The story behind the emergence of the field is told and followed by comprehensive reviews of the enzymology, regulations and gene structures of ADP-ribosyl cyclases responsible for metabolizing cADPR and NAADP. Also covered is some of the current methodology developed for and widely used in the field. The rest of the book focuses on and details the Ca2+ signaling mechanisms and specific physiological functions of these two messengers in various cellular systems.
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