This text deals with the mathematical and statistical techniques underlying the models used to understand the population dynamics of not only HIV/AIDS, but also of other infectious diseases. Attention is given to the development of strategies for the prevention and control of the international epidemic within the frameworks of the models. The text incorporates stochastic and deterministic formulations within a unifying conceptual framework.
Prologue; Acknowledgments; Contents; 1. An Introduction to Mathematical Probability with Applications in Mendelian Genetics; 1.1 Introduction; 1.2 Mathematical Probability in Mendelian Genetics; 1.3 Examples of Finite Probability Spaces; Example 1.3.1: An Equal Frequency Model; Example 1.3.2: Partitions of an Abstract Set; Example 1.3.3: A Deterministic Case; Example 1.3.4: Inheritance of Eye Color and Sex; 1.4 Elementary Combinatorial Analysis; 1.5 The Binomial Distribution; Example 1.5.1: Distribution of Boys and Girls in Families of Size N.
The book gives an overview of developments in Quantitative Genetics and variance component analysis in an era of Big Data and Sequenced Genomes. It provides a detailed description of a direct method of estimation that will be a useful means of extracting information from a large set of data that was inconceivable 10 to 20 years ago.The book is a combination of a history of variance component analysis and a forward looking view as to how direct methods of estimation arise from the availability of big data sets and sequenced genomes of each individual in the sample.Many papers and books on quantitative genetics versions of the general linear model from statistics are useful for analyzing the data, using relatively small sets of data. In this book, new methods of direct estimation are introduced and analyzed that are appropriate for an era of big sets of data and sequences genomes. These direct methods of estimation are based on taking conditional expectations rather the methods of least squares that characterize many applications of the general linear model of statistics.
Everything you need to design and produce high definition DVDs-from three of the most well-known specialists in the industry High Definition DVD Handbook is your one-stop resource for mastering the new HD DVD and Blu-ray Disc formats and successfully applying them to the entire DVD process-from authoring to design to production. You'll see how to fully utilize the amazing new resolution and features of high definition DVD, understand the major differences between the formats, navigate complex specs, and set up for either small- or large-scale production. Featuring a foreword by Jim Taylor, coauthor of DVD Demystified, this practical, irreverent guide: Gives you comprehensive, up-to-date coverage of both new competing high definition DVD formats Covers all-new, high definition authoring tools Includes chapters devoted to audio and video acquisition, graphics design, compression, quality control, and replication Reveals how to achieve new levels of interactivity through graphic user interfaces (GUIs) Provides proven advice on avoiding production pitfalls and troubleshooting Helps you navigate and utilize content protection and digital rights management as well as the Advanced Access Content System (AACS) standard Taking DVD Demystified to the next level, High Definition DVD Handbook is your guide to the new wave of DVD production. “should be required reading in any world-class DVD facility.” -Benn Carr, VP of New Technology, Walt Disney Studios, Burbank, CA
A multidisciplinary approach to understanding the fundamentals of mass spectrometry for bacterial analysis From chemotaxonomy to characterization of targeted proteins, Identification of Microorganisms by Mass Spectrometry provides an overview of both well-established and cutting-edge mass spectrometry techniques for identifying microorganisms. A vital tool for microbiologists, health professionals, and analytical chemists, the text is designed to help scientists select the most effective techniques for use in biomedical, biochemical, pharmaceutical, and bioterror defense applications. Since microbiological applications of mass spectrometry require a basic understanding of both microbiology and analytical chemistry, the editors have incorporated material from both disciplines so that readers from either field will come to understand the necessary principles of the other. Featuring contributions from some of the most recognized experts in both fields, this volume provides specific examples of fundamental methods as well as approaches developed in the last decade, including: * Metastable atom bombardment pyrolysis mass spectrometry * Matrix-assisted laser desorption/ionization mass spectrometry (MALDI) * MALDI time-of-flight mass spectrometry (MALDI-TOF MS) of intact bacteria * High-resolution Fourier transform mass spectrometry (FTMS) * Electrospray ionization (ESI) mass spectrometry Identification of Microorganisms by Mass Spectrometry represents the most comprehensive and up-to-date work on the topic currently available. It is liberally illustrated with figures and tables and covers every aspect of spectrometric identification of microorganisms, including experimental procedures, various means of sample preparation, data analysis, and interpretation of complex mass spectral data.
Second edition of classic reference contains comprehensive coverage of experimental techniques, theoretical and practical aspects of ESR instrumentation. Recent developments, plus how to build, use ESR spectrometer. References. 1982 edition.
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