Expert, Practical Advice for Everyone in Show Business Now updated and expanded, this second edition of The Stage Producer’s Business and Legal Guide is the ultimate survival kit for anyone presenting live entertainment. The information contained in this handbook is essential for those working in Broadway, regional, stock, or university theater; concert halls; opera houses; and more. Attorney, producer, and playwright Charles Grippo provides comprehensive advice on every aspect of the theater business and the law, including: Crowdfunding Your Production New Opportunities to Raise Money Self-Production Licensing and Producing Plays Devised Theater and Collaborations Creating Jukebox Musicals Organizing a Theater Company Theatrical Insurance Maintaining a Harassment-Free Environment Negotiating Contracts Essential Rules Every Board Member Must Know Managing a Not-for-Profit Theater Company Navigating Taxes Using Third-Party Intellectual Property And much, much more! The entire range of individuals involved in entertainment—producers, performers, writers, directors, managers, and theater owners—will find invaluable practical and legal advice in this handy guide.
Expert, Practical Advice for Everyone in Show Business Now updated and expanded, this second edition of The Stage Producer’s Business and Legal Guide is the ultimate survival kit for anyone presenting live entertainment. The information contained in this handbook is essential for those working in Broadway, regional, stock, or university theater; concert halls; opera houses; and more. Attorney, producer, and playwright Charles Grippo provides comprehensive advice on every aspect of the theater business and the law, including: Crowdfunding Your Production New Opportunities to Raise Money Self-Production Licensing and Producing Plays Devised Theater and Collaborations Creating Jukebox Musicals Organizing a Theater Company Theatrical Insurance Maintaining a Harassment-Free Environment Negotiating Contracts Essential Rules Every Board Member Must Know Managing a Not-for-Profit Theater Company Navigating Taxes Using Third-Party Intellectual Property And much, much more! The entire range of individuals involved in entertainment—producers, performers, writers, directors, managers, and theater owners—will find invaluable practical and legal advice in this handy guide.
Cellular and Molecular Targets for Chemoprevention provides comprehensive coverage of target mechanisms that have proved valuable in chemoprevention research, in addition to mechanisms that may prove valuable in the near future. The book discusses such topics as growth factor receptor modulation, cell-to-cell communication, differentiation modulation, antisense olgonucleotides, tumor suppressor genes, free radical scavengers, and polyamine synthesis inhibition. Cellular and Molecular Targets for Chemoprevention will be welcomed by scientists in all areas of cancer/chemoprevention research, pharmaceutical researchers, and advanced students.
Kentucky State Representative Charles Booker tells the improbable story of his journey from one of the poorest neighborhoods in the country to a political career forging new alliances among forgotten communities across the New South and beyond. “Charles Booker is a rising leader in our nation, and an inspiration to me and all those who get to know his story and vision.”—Senator Cory Booker Charles Booker grew up in one of the poorest neighborhoods in Kentucky, living in the largely segregated West End of Louisville. Faith and love were everything in his family, but material comforts were scarce. The electricity was sometimes shut off. His mother often went hungry so her son could eat. Even after he graduated from law school, Booker rationed the insulin he took for diabetes. Determined to build a world in which poverty and racism would not plague future generations, he charted his own course into Kentucky politics, a world dominated by the myth of an urban-rural divide, and controlled by the formidable Republican establishment. In this stirring account, Booker unfolds his journey from the heart of Louisville to the deepest reaches of Kentucky’s rural landscapes, reflecting the journey America itself must make on the way to a progressive future. Robbed of multiple family members by gun violence, Booker found the roots of a system built to fail him and his neighbors in everything from the hypocrisy of elected officials to the structural racism embedded in the state’s budget. Yet it wasn’t until his unlikely appointment to the Department of Fish and Wildlife Resources that he understood the transformative power of the issues that bound his family with those in rural Appalachia. In coal country, he met citizens who, like those in the West End, suffered from extreme isolation, for whom fresh food and economic stability were scarce, who lacked the resources to overcome their cynicism about change. Through his work as the youngest Black state legislator in Kentucky, Booker built an unprecedented alliance between the hood and the holler. This coalition was the basis for a thrilling grassroots Senate campaign that nearly stunned the nation, putting Senators Mitch McConnell and Rand Paul on notice that the days of business as usual were over. From the Hood to the Holler is both a moving coming-of-age story and an urgent political intervention—a much-needed blueprint for how equity and racial justice might transcend partisan divisions in Kentucky, throughout the South, and across America.
What would happen if Olympic athletes were allowed to enhance themselves in whatever way they liked to improve their chances of winning? Mister Winner follows the journey of two people who do just that. Bunny, a streetwise and gorgeous money hunter, tries to sell her fiance, Lynx, to Cavalisto Thyrax, a castrated developer of sports stadiums. Lynx is an Olympic gold medal winner and Cavalisto wants him as a prime breeding stud for his herd of athletes. Lynx avoids the plot but, and as a result of the incident, decides to devote his life to helping La Trompette, a tiny heroin addict, to overcome her physical limitations and win gold at the St Petersberg Olympics. After all, why should small weedy people be excluded from the games? Mello, a man made of huge parcels of muscle, along with 12 struck-off Romanian doctors, pitch in and try to help Lynx while Bunny recruits the Chief Umpire to achieve her aims.
The ultimate goal of cancer chemoprevention research and development is the identification of pharmaceutical or dietary constituents that will prevent cancer. Cancer Chemoprevention presents the proceedings of a large workshop on cancer chemoprevention that highlights the latest knowledge in the field, in addition to issues and ideas concerning future directions. Retinoids, sulfur compounds, and a large number of many naturally occurring cancer inhibitors in the diet are discussed, including green tea, garlic constituents, citrus fruit oils, and beans and seeds containing protease inhibitors. Compounds that may prevent the formation of carcinogens in food are covered, and the mechanisms by which chemical or dietary agencts produce cancer inhibitors are discussed.
This book starts with illustrations of the ubiquitous character of optimization, and describes numerical algorithms in a tutorial way. It covers fundamental algorithms as well as more specialized and advanced topics for unconstrained and constrained problems. This new edition contains computational exercises in the form of case studies which help understanding optimization methods beyond their theoretical description when coming to actual implementation.
Imaging of the Spine—an exhaustive, full-color reference—combines the ease of use of an atlas with the comprehensive coverage of a definitive reference work. Renowned experts Drs. Thomas P. Naidich, Mauricio Castillo, Charles Raybaud, James G. Smirniotopoulos, Soonmee Cha, and Spyros Kollias cover every aspect of spine imaging, including the latest diagnostic modalities, interventional techniques, and image-guided procedures through over 1300 digital quality illustrations. - View 1300 digital quality images of both radiographic images and cutting edge modalities—MR, multislice CT, ultrasonography, and nuclear medicine. - Consult the expertise of a diverse group of experts from around the globe on the imaging of the spine. - Tap into comprehensive coverage that includes diagnostic and therapeutic options, with an emphasis on cost-effective imaging. - Find information quickly and easily thanks to consistent and tightly focused chapters, a full color design, and key points boxes.
Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology.
Here is a complete, easy-to-use resource for anyone involved in the performing arts! This expanded edition contains 33 indispensable, hard-to-find contracts and forms that will save artists and performing groups thousands of dollars in lawyer’s fees, while minimizing their legal risks. Attorney/producer/playwright Charles Grippo explains the proper use of each form in clear, concise language. No matter which side of the negotiating table you’re on, you’ll find plenty of practical advice to help you obtain the best possible deal. These ready-to-use forms and contracts cover every aspect of theater law, including author agreements, commissions, production license, play publishing, and more. Also included on a convenient CD-ROM, the forms can be copied electronically, modified, customized, and saved. New to this edition are contracts for performing arts designers; fight and stunt directors; musicians; stage managers and technical directors; front of the house personnel; commissions for original musical compositions; and much more. From producers and directors, to performers and choreographers, to theatrical designers and box office managers, this volume is a necessity for anyone involved in the performing arts.
Trust the #1 selling ultrasonography study guide—1,000+ images, 3,000 review questions/answers, content from leading experts in the field Lange Review Ultrasonography Examination has long been the go-to guide for anyone seeking certification or recertification in ultrasonography. This unbeatable study aid summarizes the entire ultrasonography curriculum in concise, readable narrative, helping you understand and retain key concepts. Covering the latest ultrasonography technologies and techniques, this new edition brings you fully up to date on the topics you need to know most—and it includes all-new chapters on 3D sonography in obstetrics and gynecology, musculoskeletal ultrasound, and breast sonography. With its authoritative and engaging coverage combined with thousands of sample questions and detailed answers that reinforce learning, Lange Review Ultrasonography Examination provides the fully rounded learning experience you need to ace the exam.
A concise, outline-format review of the curriculum based on the ARDMS content outline More than 3,000 registry-format review questions and answers with complete explanations NEW chapters on 3D sonography in obstetrics and gynecology, musculoskeletal sonography, and breast sonography NEW: Now includes an index to make locating information seamless Fully referenced to core books students are likely to have on hand for further study
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