The Process of New Drug Discovery and Development presents a practical methodology for maximizing the ability of a multidisciplinary research team to discover and bring new drugs to the marketplace. It includes detailed discussions regarding the research process and presents critiques of the governmental regulatory aspects of pharmaceutical research. The author also addresses the controversy surrounding the use of animals in biomedical research and provides current information regarding the field of biotechnology, international drug research, and registration activities. The Process of New Drug Discovery and Development is an excellent "how to" text for pharmaceutical researchers, oncologists, biochemists, experimental biologists, and others involved in new drug research and development.
William Watson Cheyne (1852-1932), a surgeon by training and a student of Joseph Lister, was a prominent British bacteriologist who published 60 papers and 13 monographs from 1879 to 1927. A proponent of the idea that bacteriology and medicine were interdependent disciplines, he investigated the causes and treatment of wound infections, tuberculosis, cholera, tetanus and gangrene. In 1897, he organized an historical outline of 19th century bacteriology in five landmark periods of discovery, each defined by the work of an influential figure. This study documents his contributions to the history of microbiology and describes his activities as a laboratory investigator, clinician, surgeon, translator, editor and educator.
Are colleges and universities in a period of unprecedented disruption? Is a bachelor's degree still worth the investment? Are the humanities coming to an end? What, exactly, is higher education good for? In For the Common Good, Charles Dorn challenges the rhetoric of America's so-called crisis in higher education by investigating two centuries of college and university history. From the community college to the elite research university—in states from California to Maine—Dorn engages a fundamental question confronted by higher education institutions ever since the nation's founding: Do colleges and universities contribute to the common good? Tracking changes in the prevailing social ethos between the late eighteenth and early twenty-first centuries, Dorn illustrates the ways in which civic-mindedness, practicality, commercialism, and affluence influenced higher education's dedication to the public good. Each ethos, long a part of American history and tradition, came to predominate over the others during one of the four chronological periods examined in the book, informing the character of institutional debates and telling the definitive story of its time. For the Common Good demonstrates how two hundred years of political, economic, and social change prompted transformation among colleges and universities—including the establishment of entirely new kinds of institutions—and refashioned higher education in the United States over time in essential and often vibrant ways.
Outside the Lines traces how sports laid a foundation for social change long before the judicial system formally recognized the inequalities of racial separation. Integrating sports teams to include white and black athletes alike, the National Football League served as a microcosmic fishbowl of the highs and lows, the trials and triumphs, of racial integration. Watching a football game on a Sunday evening, most sports fans do not realize the profound impact the National Football League had on the civil rights movement. Similarly, in a sport where seven out of ten players are black, few are fully aware of the history and contributions of their athletic forebears. Among the touchdowns and tackles lies a rich history of African American life and the struggle to achieve equal rights. Although the Supreme Court did not reverse their 1896 decision of "separate but equal" in the Plessy v Ferguson case until more than fifty years later, sports laid a foundation for social change long before our judicial system formally recognized the inequalities of racial separation. Integrating sports teams to include white and black athletes alike, the National Football League served as a microcosmic fishbowl of the highs and lows, the trials and triumphs, of racial integration. In this chronicle of black NFL athletes, Charles K. Ross has given us the story of the Jackie Robinsons of American football.
Handbook of Chromatography features tables and chromatograms, theoretical discussions, and practical applications on the topic. Tables and chromatograms are based on polymer analyses abstracted from literature references dating from 1981-1991. Compounds presented in the tables and chromatograms include residual monomers, plasticizers, additives, antioxidants, and products from the thermal degradation (pyrolysis) of a broad range of synthetic polymers. Theoretical discussions focus on new developments in the respective areas of gas, pyrolysis-gas, liquid, and size exclusion chromatographic separations. Capillary column technology, inverse gas chromatography (IGC), supercritical fluid extractions (SFE), and supercritical fluid chromatography (SFC) are also covered. A Practical Applications subsection provides a list of commercial suppliers of column packings and packed columns for gas and liquid chromatography. The book will be an excellent reference for chromatographers, organic chemists, and analytical chemists.
A comprehensive and beautifully illustrated overview to the birds of Maine The first comprehensive overview of Maine’s incredibly rich birdlife in more than seven decades, Birds of Maine is a detailed account of all 464 species recorded in the Pine Tree State. It is also a thoroughly researched, accessible portrait of a region undergoing rapid changes, with southern birds pushing north, northern birds expanding south, and once-absent natives like Atlantic Puffins brought back by innovative conservation techniques pioneered in Maine. Written by the late Peter Vickery in cooperation with a team of leading ornithologists, this guide offers a detailed look at the state’s dynamic avifauna—from the Wild Turkey to the Arctic Tern—with information on migration patterns and timing, current status and changes in bird abundance and distribution, and how Maine's geography and shifting climate mold its birdlife. It delves into the conservation status for Maine's birds, as well as the state's unusually textured ornithological history, involving such famous names as John James Audubon and Theodore Roosevelt, and home-grown experts like Cordelia Stanwood and Ralph Palmer. Sidebars explore diverse topics, including the Old Sow whirlpool that draws multitudes of seabirds and the famed Monhegan Island, a mecca for migrant birds. Gorgeously illustrated with watercolors by Lars Jonsson and scores of line drawings by Barry Van Dusen, Birds of Maine is a remarkable guide that birders will rely on for decades to come. Copublished with the Nuttall Ornithological Club
Faith in Paper is about the reinstitution of Indian treaty rights in the Upper Great Lakes region during the last quarter of the 20th century. The book focuses on the treaties and legal cases that together have awakened a new day in Native American sovereignty and established the place of Indian tribes on the modern political landscape. In addition to discussing the historic development of Indian treaties and their social and legal context, Charles E. Cleland outlines specific treaties litigated in modern courts as well as the impact of treaty litigation on the modern Indian and non-Indian communities of the region. Faith in Paper is both an important contribution to the scholarship of Indian legal matters and a rich resource for Indians themselves as they strive to retain or regain rights that have eroded over the years. Charles E. Cleland is Michigan State University Emeritus Professor of Anthropology and Curator of Anthropology and Ethnology. He has been an expert witness in numerous Native American land claims and fishing rights cases and written a number of other books on the subject, including Rites of Conquest: The History and Culture of Michigan's Native Americans; The Place of the Pike (Gnoozhekaaning): A History of the Bay Mills Indian Community; and (as a contributor) Fish in the Lakes, Wild Rice, and Game in Abundance: Testimony on Behalf of Mille Lacs Ojibwe Hunting and Fishing Rights.
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