The political and economic changes that occurred in the Soviet Union in the six and one-half years of Mikhail Gorbachev's tenure as General Secretary were breathtaking in their scope and rapidity, going far beyond most observeiS' expectatiom. Certainly, the process of refonn which we call perestroilal transfonned the ossified one-party socialist state that had prevailed underGorbachev's predecessors. The reasons for embarking on such a coume of reform were varied-eamomic aism and a decline in the Soviet state's ability to provide social welfare services for its citizens, an increasingly apathetic population, and a tense international environment-all of these factoiS convinced the Soviet leadeiShip of the necessity of drastic change. The policies of Gorbachev set refonn in motion: freeing public expression (glllsnost); encouraging economic decentralization and private initiative; and creating a more cooperative relationship with the West.
Understanding development in Latin America today requires both an awareness of the major political and economic changes that have produced a new agenda for social policy in the region and an appreciation of the need to devise better conceptual and methodological tools for analyzing the social impact of these changes. Using as a reference point the issues and theories that dominated social science research on Latin America in the period 1960&–80, this volume contributes to &“rethinking development&” by examining the historical events that accounted for the erosion or demise of once-dominant paradigms and by assessing the new directions of research that have emerged in their place. Following the editors&’ overview of the new conceptual and social agendas in their Introduction, the book proceeds with a review of previous broad conceptual approaches by Alejandro Portes, who emphasizes by contrast the advantages of newer &“middle-range&” theories. Subsequent chapters focus on changes in different arenas and the concepts and methods used to interpret them: &“Globalization, Neoliberalism, and Social Policy&”; &“Citizenship, Politics, and the State&”; &“Work, Families, and Reproduction&”; and &“Urban Settlements, Marginality, and Social Exclusion.&” Contributors, besides the editors, are Marina Ariza and Orlandina de Oliveira, Diane Davis, Vilmar Faria, Joe Foweraker, Elizabeth Jelin, Alejandro Portes, Joe Potter and Rudolfo Tuir&án, Juan Pablo P&érez S&áinz, Osvaldo Sunkel, and Peter Ward.
More than 1400 terms useful in wildland and related resource planning are defined. The purpose of the work is to facilitate communication between professionals, not to provide them with exhaustive vocabularies of each other's specialties. Definitions are drawn from many sources, including public laws and government manuals, but are not intended to establish legally binding definitions. A list of terms and list of sources are included. Charles Schwarz is a landscape architect in the Station's research unit on forest recreation and landscape planning, at Berkeley. Before joining the Station staff in 1975, he was a research assistant at the University of California's Institute of Urban and Regional Development, Berkeley. Edward C. Thor is an economist with the research unit. He was formerly a post-graduate research economist at the University of California, Berkeley, on assignment to the Station under a cooperative agreement. Gary H. Elsner is in charge of the unit.
This volume is part of the definitive edition of letters written by and to Charles Darwin, the most celebrated naturalist of the nineteenth century. Notes and appendixes put these fascinating and wide-ranging letters in context, making the letters accessible to both scholars and general readers. Darwin depended on correspondence to collect data from all over the world, and to discuss his emerging ideas with scientific colleagues, many of whom he never met in person. The letters are published chronologically. In 1881, Darwin published his final book, The Formation of Vegetable Mould through the Action of Worms. He reflected on reactions to his previous book, The Power of Movement in Plants, and worked on two papers for the Linnean Society on the action of carbonate of ammonia on plants. In this year, Darwin's elder brother, Erasmus, died, and a second grandchild, also named Erasmus, was born.
Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
First published in 1989. The Journal of Development Studies was founded 25 years ago as a professional journal for what had by then become an established sub-discipline within British social science. The Journal has consistently published a broad spectrum of British research on development studies - a catholicity that has been reflected in the composition of the Editorial Board over the years - and has always welcomed authors from the USA, the European Continent, and above all from the Third World. Collated form the last twenty-five years of the journal presented here are a collection of 20-odd papers that represent less than three per cent of articles published since 1964.
Latin America is one of the most intriguing parts of the world. The region’s illustrious history, culture, and geography are famous internationally, but in terms of economics, Latin America has been generally associated with problems. For many, the combination of a resource-rich region and poor economic conditions has been a puzzle. This extensively revised and updated third edition of Latin American Economic Development continues to provide the most up-to-date exploration of why the continent can be considered to have underperformed, how the various Latin American economies function, and the future prospects for the region. The book addresses the economic problems of Latin America theme by theme. Changes and new features in this new edition include: a new chapter on economic growth that reflects the new understanding of slow growth in the region; two new appendices on basic microeconomics and macroeconomics; expanded coverage on new commodities such as lithium and quinoa; a number of new boxes and updates to existing boxes; for instructors, PowerPoint presentations and an extensive test bank are available. The book provides a comprehensive text for undergraduate economics courses on Latin America and is also suitable for use by students in other disciplines looking for a wide-ranging guide to the region. This book will continue to be an invaluable resource for undergraduates looking at Latin American economics, growth, and development.
Apoptosis is the regulated form of cell death. It is a complex process defined by a set of characteristic morphological and biochemical features that involves the active participation of affected cells in a self-destruction cascade. This programmed cell death plays a critical role in physiological functions such as cell deletion during embryonic development, balancing cell number in continuously renewing tissues and immune system development. Additionally, a dysregulation of apoptosis is underlying in numerous pathological situations such as Parkinson, Alzheimer's disease and cancer. A number of studies have pointed out an association between consumption of fruits and vegetables, and certain beverages such as tea and wine, which are rich in polyphenols, with reduced risk of chronic diseases, including cancer. Apoptosis is also the regulatory mechanism involved in the removal of unnecessary cells during development and in tissue homeostasis in a wide range of organisms from insects to mammals. This book focuses on cell apoptotic signalling pathways.
First Published in 2015. Classic and contemporary Marxist theoretical works on imperialism are systematically summarized and critiqued in this useful survey. Throughout the discussion, attention is focused analyses of the causes of capitalist foreign economic expansion and the impact of that expansion. The study begins with a discussion of Marx's political economy and the work of early theorists of imperialism, Vladimir Lenin, Rosa Luxemburg, Nikolai Bukharin and Rudolf Hilferding. This analysis then serves as the basis for a critical survey of the major strands of postwar Marxist thought, including the work of Paul Baran and Paul Sweezy, Harry Madgdoff, James O'Connor, Andre Gunder Frank and more, Following the survey ae extended critiques of Baran and Sweezy's theory of monopoly capitalism and Arghiri Emmanuels' theory of unequal exchange.
Since its publication in 2004, Doing Honest Work in College has become an integral part of academic integrity and first-year experience programs across the country. This helpful guide explains the principles of academic integrity in a clear, straightforward way and shows students how to apply them in all academic situations—from paper writing and independent research to study groups and lab work. Teachers can use this book to open a discussion with their students about these difficult issues. Students will find a trusted resource for citation help whether they are studying comparative literature or computer science. Every major reference style is represented. Most important of all, many universities that adopt this book report a reduction in cheating and plagiarism on campus. For this second edition, Charles Lipson has updated hundreds of examples and included many new media sources. There is now a full chapter on how to take good notes and use them properly in papers and assignments. The extensive list of citation styles incorporates guidelines from the American Anthropological Association. The result is the definitive resource on academic integrity that students can use every day. “Georgetown’s entering class will discover that we actually have given them what we expect will be a very useful book, Doing Honest Work in College. It will be one of the first things students see on their residence hall desks when they move in, and we hope they will realize how important the topic is.”—James J. O’Donnell, Provost, Georgetown University “A useful book to keep on your reference shelf.”—Bonita L. Wilcox, English Leadership Quarterly
The text is translated into English from the Third French edition of 1619, and edited, with notes. This volume covers from 1601 to Pyrard's arrival at Goa in 1608 and is continued in First Series 77 and 80. This is a new print-on-demand hardback edition of the volume first published in 1887.
This book constructs the model of economic development implicit in the historical experience of the Soviet Union, and the agricultural, industrial, and social strategies followed are shown to fit into a logical and coherent pattern. Those strategies are then evaluated for the positive and negative answers they hold for underdeveloped countries today. Originally published 1969. A UNC Press Enduring Edition -- UNC Press Enduring Editions use the latest in digital technology to make available again books from our distinguished backlist that were previously out of print. These editions are published unaltered from the original, and are presented in affordable paperback formats, bringing readers both historical and cultural value.
Hemodynamics and Cardiology, a volume in Dr. Polin’s Neonatology: Questions and Controversies Series, offers expert authority on the toughest cardiovascular challenges you face in your practice. This medical reference book will help you provide better evidence-based care and improve patient outcomes with research on the latest advances. Reconsider how you handle difficult practice issues with coverage that addresses these topics head on and offers opinions from the leading experts in the field, supported by evidence whenever possible. Find information quickly and easily with a consistent chapter organization. Get the most authoritative advice available from world-class neonatologists who have the inside track on new trends and developments in neonatal care. Stay current in practice with coverage on issues such as the clinical implications of near-infrared spectroscopy in neonates, MRI imaging and neonatal hemodynamics, and hybrid management techniques for congenital heart disease.
This newest addition of the comprehensive Pediatric Neuroimaging combines thousands of images with detailed textual descriptions to help you diagnose a wide range of brain, spinal, and head and neck disorders in the pediatric patient. The authors have chosen a clear, concise writing style that encourages you to grasp information quickly. By dealing with a broad range of disorders, from everyday problems to less common ones, and explaining how to recognize and differentiate them, this book offers you the opportunity to provide a concise differential diagnosis on most patients you are likely to encounter in your practice.
Hemodynamics and Cardiology, a volume in Dr. Polin's Neonatology: Questions and Controversies Series, offers expert authority on the toughest cardiovascular challenges you face in your practice. This medical reference book will help you provide better evidence-based care and improve patient outcomes with research on the latest advances. Reconsider how you handle difficult practice issues with coverage that addresses these topics head on and offers opinions from the leading experts in the field, supported by evidence whenever possible. Find information quickly and easily with a consistent chapter organization. Get the most authoritative advice available from world-class neonatologists who have the inside track on new trends and developments in neonatal care. Purchase each volume individually, or get the entire 6-volume set, which includes online access that allows you to search across all titles! Stay current in practice with coverage on issues such as the clinical implications of near-infrared spectroscopy in neonates, MRI imaging and neonatal hemodynamics, and hybrid management techniques for congenital heart disease. Access the fully searchable text online at www.expertconsult.com.
Arguing that Americans make political choices in terms of a general notion of right and wrong, yet lack a sound, objective foundation for such values, evangelical scholar Stephen Mott formulates a Christian political theory that supplies such norms. Drawing on theological and biblical sources, Mott thoroughly develops the biblical and theological foundations for politics and political evaluation. Mott proposes that political philosophies should be evaluated in light of Christian theological and ethical values--specifically the understanding of power, human nature, the nature of group life, justice and love, government, and time. He then applies this critical framework in an evaluation of political ideologies, including traditional conservatism, liberalism, democracy, laissez-faire conservatism, Marxist socialism, and democratic socialism. He gives special attention to their classical exponents and ideas. Asserting that political visions ultimately depend on cultural values that themselves require vigorous religious faith in a particular society, Mott's study offers a valuable introduction to Christian political thought as well as an illuminating look at the connection between politics and religion.
For more than 60 years, Shackelford's Surgery of the Alimentary Tract has served as the cornerstone reference in this fast-moving field. With comprehensive coverage of all aspects of GI surgery, the 8th Edition, by Drs. Charles J. Yeo, Steven R. DeMeester, David W. McFadden, Jeffrey B. Matthews, and James W. Fleshman, offers lavishly illustrated, authoritative guidance on endoscopic, robotic, and minimally invasive procedures, as well as current medical therapies. Each section is edited by a premier authority in GI surgery; chapters reflect key topics and are written by a "who's who" of international experts in the field. It's your one-stop resource for proven, systematic approaches to all relevant adult and pediatric GI disorders and operations - Features an abundance of beautifully detailed intraoperative and laparoscopic photographs, as well as radiographs and line drawings, to enhance and clarify the text. - Presents essential information, such as lists of differential diagnoses, in tabular format for quick reference. - Discusses recent, major advances in minimally invasive surgery and robotic surgery, personalized therapy based on genomics and proteomics, and new pharmacologic treatments of various GI diseases. - Includes all-new information on laparoscopy for rectal cancer, sacral nerve stimulation for incontinence and constipation, management of Crohn's disease and ulcerative colitis, advances in immunosuppression for transplant patients, and new therapies for inflammatory bowel disease. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
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