Charles DeLisi's Books

Mysterious Commonplace, The: A Life In Science

By: Charles Delisi

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Mysterious Commonplace, The: A Life In Science

By: Charles Delisi

Acclaimed biomedical scientist Charles DeLisi tells the story of the rewards and frustrations of a life in science. The memoir spans half a century beginning in grade school when we find a somewhat shy boy deeply affected by the profoundly saddening sight of trees and woods in his beloved Bronx neighborhood being displaced by tons of steel and concrete. The reader is taken inside the mind of a complex non-conformist as he struggles with personal tragedy and ambivalence and moves from physics to history back to physics, and eventually into a career as a biomedical scientist. Among the most important parts of the memoir are his personal recollections of the years as director of the Department of Energy's Health and Environmental Research Programs when he fought the mighty battles that would move two Federal Agencies and place the Human Genome Project, including a unique ethical component, on the National Agenda. We watch an uncannily successful strategist and leader; who sees himself as an ordinary person, distinguished only by an intense passion for science, as he and his colleagues successfully engage Congressmen, his superiors at the DOE, and scientists of different backgrounds. The story closes where it began, with environmental change dominating the emotional landscape, as he and his colleagues struggle to fight the battle against a changing climate.

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221

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World Scientific

Published Date

ISBN 10

9811238472

ISBN 13

9789811238475

Mysterious Commonplace, The: A Life In Science

By: Charles Delisi

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Mysterious Commonplace, The: A Life In Science

By: Charles Delisi

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221

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World Scientific

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ISBN 10

9811238472

ISBN 13

9789811238475

Genome Informatics 2009

Proceedings of the 9th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2009) : Boston University, Boston, USA, 27-29 July 2009

By: Charles DeLisi

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Genome Informatics 2009

Proceedings of the 9th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2009) : Boston University, Boston, USA, 27-29 July 2009

By: Charles DeLisi

This volume contains 17 peer-reviewed papers based on the presentations at the 9th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2009) held at the Life Science Engineering Building of Boston University from July 27 to 29, 2009. This workshop started in 2001 as a platform for doctoral students and young researchers to present and discuss their research results and approaches in bioinformatics and systems biology. It is part of a collaborative educational program involving leading institutions and leaders committed to the following institutions and programs: * Boston University Graduate Program in Bioinformatics * Charit Universittsmedizin Berlin * Freie Universitt Berlin * Global COE Program Center of Education and Research for Advanced Genome-Based Medicine, University of Tokyo * The International Research Training Group (IRTG) Genomics and Systems Biology of Molecular Networks * International Research and Training Program on Bioinformatics and Systems Biology, Kyoto University Bioinformatics Center * Max-Delbrck Center for Molecular Medicine in Berlin * Max Planck Institute for Molecular Genetics in Berlin * Max Planck Institute of Molecular Plant Physiology in Potsdam

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215

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World Scientific

Published Date

ISBN 10

1848165781

ISBN 13

9781848165786

Offender Rehabilitation Issues

Critical Lessons for Criminology, Criminal Justice, and Public Policy

By: Charles B.A. Ubah

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Offender Rehabilitation Issues

Critical Lessons for Criminology, Criminal Justice, and Public Policy

By: Charles B.A. Ubah

Most of the studies that discuss offender rehabilitation focus on the debate over whether prison-based education programs work, ignoring the important issues that these programs undertake. Using a critical approach, Offender Rehabilitation Issues: Critical Lessons for Criminology, Criminal Justice, and Public Policy fills the gap by highlighting the offender rehabilitation programs that continue to divide scholars, policy makers, correctional practitioners, students, and the public. This book demonstrates and reaffirms that offender rehabilitation programs and recidivism rates are important and critical social issues that do not exist in a vacuum, are complex interacting social processes and issues with broader social, economic, legal, and political environmental forces and pressures.

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163

Publisher

Lexington Books

Published Date

ISBN 10

1666922803

ISBN 13

9781666922806

T-Cell Dependent and Independent B-Cell Activation

By: E. Charles Snow

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T-Cell Dependent and Independent B-Cell Activation

By: E. Charles Snow

This book provides an analysis of the current subdisciplines comprising the study of humoral immune response. The first chapter presents a detailed discussion regarding the experimental and conceptual studies conducted prior to the mid-1970s that have served as a valuable research framework for investigators interested in the process by which B cells are activated following their exposure to antigens. Other chapters focus on topics such as membrane-associated proteins with important functional roles during B cell activation and differentiation; thymus-independent and thymus-dependent activation; mechanisms operative during B-T cell interactions, including the role of B cells as antigen-presenting cells; and the importance of soluble mediators. Additional topics include the regulatory role of T cells during B cell repertoire expression, memory development, tolerance, and autoimmunity. T-Cell Dependent and Independent B-Cell Activation is an important history and reference resource for humoral immune response investigators, as well as advanced graduate and medical students.

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314

Publisher

CRC Press

Published Date

ISBN 10

0849368197

ISBN 13

9780849368196

Cellular and Molecular Targets for Chemoprevention

By: Vernon E. Steele,Gary D. Stoner,Gary J. Kelloff,Charles W. Boone

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Cellular and Molecular Targets for Chemoprevention

By: Vernon E. Steele,Gary D. Stoner,Gary J. Kelloff,Charles W. Boone

Cellular and Molecular Targets for Chemoprevention provides comprehensive coverage of target mechanisms that have proved valuable in chemoprevention research, in addition to mechanisms that may prove valuable in the near future. The book discusses such topics as growth factor receptor modulation, cell-to-cell communication, differentiation modulation, antisense olgonucleotides, tumor suppressor genes, free radical scavengers, and polyamine synthesis inhibition. Cellular and Molecular Targets for Chemoprevention will be welcomed by scientists in all areas of cancer/chemoprevention research, pharmaceutical researchers, and advanced students.

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400

Publisher

CRC Press

Published Date

ISBN 10

0849345308

ISBN 13

9780849345302

The American Psychiatric Publishing Textbook of Psychopharmacology

By: Alan F. Schatzberg,Charles B. Nemeroff

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The American Psychiatric Publishing Textbook of Psychopharmacology

By: Alan F. Schatzberg,Charles B. Nemeroff

Now updated to keep professionals current with the latest research and trends in the field, this edition covers both basic science and clinical practice, and draws on the talents of 53 new contributors to guarantee fresh, authoritative perspectives on advances in psychiatric drug therapy.

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933

Publisher

American Psychiatric Pub

Published Date

ISBN 10

1585623091

ISBN 13

9781585623099

Using Multiliteracies and Multimodalities to Support Young Children′s Learning

By: Marie Charles,Bill Boyle

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Using Multiliteracies and Multimodalities to Support Young Children′s Learning

By: Marie Charles,Bill Boyle

′This is a timely book that effectively challenges the current emphasis on a homogeneous approach to teaching, learning, and assessment in early literacy. It encourages us to engage with the real world complexity of young children’s learning and offers a series of rich and detailed examples of this in practice.′ - Sally Neaum,Teesside and Durham Universities, and Author of Beyond Early Reading Grounded in classroom practice, this practical book shows trainees and current teachers how to scaffold children’s literacy using a creative and supportive approach. It offers teaching strategies for Multiliteracies (fiction, expository/instructions, poetry, recount) and Multimodalities (reading, writing, speaking, listening, performing, illustrating) and helps to develop a relationship between teacher and learner. Chapter topics include: socio-dramatic play collaboration guided group teaching strategies integration of genres. This clear and accessible book will be extremely valuable to students and practitioners on PGCE programmes, B.Eds, Masters, workshop and conference CPD, and advanced Teaching Assistant training. Marie Charles is a teacher, formative assessment researcher and consultant. Professor Bill Boyle was until recently Director of CFAS in the School of Education, University of Manchester. Both authors are regularly involved in school-based research across England and international teacher training programmes.

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161

Publisher

SAGE

Published Date

ISBN 10

1473905613

ISBN 13

9781473905610

Genomics

The Science and Technology Behind the Human Genome Project

By: Charles R. Cantor,Cassandra L. Smith

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Genomics

The Science and Technology Behind the Human Genome Project

By: Charles R. Cantor,Cassandra L. Smith

A unique exploration of the principles and methods underlying the Human Genome Project and modern molecular genetics and biotechnology-from two top researchers In Genomics, Charles R. Cantor, former director of the Human Genome Project, and Cassandra L. Smith give the first integral overview of the strategies and technologies behind the Human Genome Project and the field of molecular genetics and biotechnology. Written with a range of readers in mind-from chemists and biologists to computer scientists and engineers-the book begins with a review of the basic properties of DNA and the chromosomes that package it in cells. The authors describe the three main techniques used in DNA analysis-hybridization, polymerase chain reaction, and electrophoresis-and present a complete exploration of DNA mapping in its many different forms. By explaining both the theoretical principles and practical foundations of modern molecular genetics to a wide audience, the book brings the scientific community closer to the ultimate goal of understanding the biological function of DNA. Genomics features: * Topical organization within chapters for easy reference * A discussion of the developing methods of sequencing, such as sequencing by hybridization (SBH) in which data is read through words instead of letters * Detailed explanations and critical evaluations of the many different types of DNA maps that can be generated-including cytogenic and restriction maps as well as interspecies cell hybrids * Informed predictions for the future of DNA sequencing

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621

Publisher

John Wiley & Sons

Published Date

ISBN 10

0471461865

ISBN 13

9780471461869

Policy Strategy and Innovation Primer

Process, Praxis and Tools

By: Charles Chao Rong Phua

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Policy Strategy and Innovation Primer

Process, Praxis and Tools

By: Charles Chao Rong Phua

Phua focuses on applying the best of corporate strategy and innovation tools and praxis into the policy process with the aim of devising a coherent policy strategy–innovation framework and process. Government and business strategies differ in their operating assumptions and variables, but the strategy process is more similar than is often perceived. Phua debunks the government versus business dichotomy and demonstrates the potential for cross-learning between both domains. Readers will benefit the most by reading this book in tandem with Phua’s other works on strategy also featured in this series. This book is an essential primer for academics, practitioners and learners of public policy, strategy, innovation and applied problem-solving.

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165

Publisher

Taylor & Francis

Published Date

ISBN 10

1000836495

ISBN 13

9781000836493

Mind Stimulation Therapy

Cognitive Interventions for Persons with Schizophrenia

By: Mohiuddin Ahmed,Charles M. Boisvert

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Mind Stimulation Therapy

Cognitive Interventions for Persons with Schizophrenia

By: Mohiuddin Ahmed,Charles M. Boisvert

This book presents a psychotherapy intervention model called Multimodal Integrative Cognitive Stimulation Therapy (MICST). It is grounded in information processing and cognitive stimulation techniques and operates out of a positive psychology framework. This model, designed for group work with clients with schizophrenia, can be easily tailored to working with clients in individual therapy sessions. The three core MICST group activities include: 1) body movement-mindfulness-relaxation (BMR); 2) cognitive stimulation using group discussions; and 3) cognitive stimulation using paper-pencil cognitive exercises and self-reflection exercises. A chapter is devoted to each of these core areas with actual case vignettes to illustrate ways that these activities can be implemented in clinical practice. Homework recommendations are included at the end of each chapter, devoted to a core MICST group activity and providing suggestions on ways to practice various skills and exercises in between group sessions. Also provided are several handouts and worksheets which can be used with clients.

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376

Publisher

Routledge

Published Date

ISBN 10

1136216367

ISBN 13

9781136216367

Community Food Webs

Data and Theory

By: Joel E. Cohen,Frédéric Briand,Charles M. Newman

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Community Food Webs

Data and Theory

By: Joel E. Cohen,Frédéric Briand,Charles M. Newman

Food webs hold a central place in ecology. They describe which organisms feed on which others in natural habitats. This book describes recently discovered empirical regularities in real food webs: it proposes a novel theory unifying many of these regularities, as well as extensive empirical data. After a general introduction, reviewing the empirical and theoretical discoveries about food webs, the second portion of the book shows that community food webs obey several striking phenomenological regularities. Some of these unify, regardless of habitat. Others differentiate, showing that habitat significantly influences structure. The third portion of the book presents a theoretical analysis of some of the unifying empirical regularities. The fourth portion of the book presents 113 community food webs. Collected from scattered sources and carefully edited, they are the empirical basis for the results in the volume. The largest available set of data on community food webs provides a valuable foundation for future studies of community food webs. The book is intended for graduate students, teachers and researchers primarily in ecology. The theoretical portions of the book provide materials useful to teachers of applied combinatorics, in particular, random graphs. Researchers in random graphs will find here unsolved mathematical problems.

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318

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3642837840

ISBN 13

9783642837845

The Skeptical Professional’s Guide to Psychiatry

On the Risks and Benefits of Antipsychotics, Antidepressants, Psychiatric Diagnoses, and Neuromania

By: Charles E. Dean

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The Skeptical Professional’s Guide to Psychiatry

On the Risks and Benefits of Antipsychotics, Antidepressants, Psychiatric Diagnoses, and Neuromania

By: Charles E. Dean

This text critically examines the shortcomings of psychiatry; the flawed development of the diagnostic system, including the DSM-5; and the failure to advance the effectiveness of antipsychotics and antidepressants. Starting with an overview of the evolution of psychiatry, Dean explores the creation, use, and misuse of medications, a process largely driven by drug companies. Other chapters describe the benefits and risks of medications, the problems associated with rational prescribing, and the embrace of so-called novel therapies including hallucinogenic drugs and opioids. Chapters end with a set of clinical notes that provide specific recommendations to clinicians, families, patients, and other providers, emphasizing the risks and benefits of treatment with medications but also stressing alternative approaches. This book will challenge clinicians to think critically about the DSM-5 and the current systems of diagnosis and treatment of mental illnesses in the hopes of ultimately improving the lives of people with mental illnesses.

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Page Count

322

Publisher

Routledge

Published Date

ISBN 10

1000245624

ISBN 13

9781000245622

CRISPR: Genome Editing and Engineering And Related Issues

By: Barbara Wexler,Michael A. Hauser,Ralph R. Meyer,Michael Dietrich,Matilde Parente,Robert C. Baumiller,Charles J. Grossman

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CRISPR: Genome Editing and Engineering And Related Issues

By: Barbara Wexler,Michael A. Hauser,Ralph R. Meyer,Michael Dietrich,Matilde Parente,Robert C. Baumiller,Charles J. Grossman

eBook content that offers a clear and comprehensive introduction to CRISPR and related topics. Entries include foundational concepts, key scientific figures and historical themes, ethical issues , and advances in the science.

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Gale, Cengage Learning

Published Date

ISBN 10

0028666682

ISBN 13

9780028666686

Rogue Prosecutors

How Radical Soros Lawyers Are Destroying America's Communities

By: Zack Smith,Charles D. Stimson

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Rogue Prosecutors

How Radical Soros Lawyers Are Destroying America's Communities

By: Zack Smith,Charles D. Stimson

Rogue Prosecutors explains the origins, beliefs, playbook, funding, and real-life consequences of the “progressive prosecutor” movement—a group of newly elected prosecutors, their allies, and backers that refuse to prosecute crimes, hold criminals accountable, and seek justice for victims. Told through true crime stories from eight different cities, the authors explore how a radical movement funded and conceived by George Soros—and ostensibly designed to “reverse engineer” the criminal justice system as we know it—has succeeded in replacing law and order prosecutors with pro-criminal, anti-victim zealots. Weaving together extensive interviews with victims, law enforcement officers, lawyers, and judges, Rogue Prosecutors offers a searing portrait of the devastation caused by the policies of these hand-picked activists, how their hands-off approach to prosecution has encouraged lawlessness and eviscerated the relationship with law enforcement, and why minorities have suffered the most in cities with “progressive prosecutors.” In story after story, the authors underscore that justice and public safety require prosecutors to hold all criminals accountable, and that the best choice for district attorney is not necessarily based on partisan politics, but between those who believe in law and order and those who don’t.

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348

Publisher

Bombardier Books

Published Date

ISBN 10

163758654X

ISBN 13

9781637586549

Perestroika In The Soviet Republics

Documents On The National Question

By: Charles F Furtado,Andrea Chandler

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Perestroika In The Soviet Republics

Documents On The National Question

By: Charles F Furtado,Andrea Chandler

The political and economic changes that occurred in the Soviet Union in the six and one-half years of Mikhail Gorbachev's tenure as General Secretary were breathtaking in their scope and rapidity, going far beyond most observeiS' expectatiom. Certainly, the process of refonn which we call perestroilal transfonned the ossified one-party socialist state that had prevailed underGorbachev's predecessors. The reasons for embarking on such a coume of reform were varied-eamomic aism and a decline in the Soviet state's ability to provide social welfare services for its citizens, an increasingly apathetic population, and a tense international environment-all of these factoiS convinced the Soviet leadeiShip of the necessity of drastic change. The policies of Gorbachev set refonn in motion: freeing public expression (glllsnost); encouraging economic decentralization and private initiative; and creating a more cooperative relationship with the West.

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588

Publisher

Routledge

Published Date

ISBN 10

1000315592

ISBN 13

9781000315592

Improving Instruction Through Supervision, Evaluation, and Professional Development

Second Edition

By: Michael DiPaola,Charles A. Wagner

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Improving Instruction Through Supervision, Evaluation, and Professional Development

Second Edition

By: Michael DiPaola,Charles A. Wagner

In this second edition of Improving Instruction Through Supervision, Evaluation, and Professional Development we’ve maintained the conceptual framework while updating sections to provide the most recent research on instructional strategies that have the most promise of helping all students learn. Modifications of the law resulting from the reauthorization of the 50-year-old Elementary and Secondary Education Act—Every Student Succeeds Act (ESSA) (2015)—and their implication for practice are embedded throughout this new edition. Updated data collection tools for classroom observations are also provided. We included a link to a website that contains all the observation tools in electronic format so that observers can have the opportunity to collect data on a tablet or laptop, save the observation data as a PDF file and e-mail those data to the teacher observed. This new edition recognizes the reality that all principals are responsible for supervision, evaluation, and professional development of their teachers—tasks that are neither simple nor without conflict. The primary audience of this text is aspiring and practicing principals. We hope to help them understand both the theory and practice of supervision, evaluation, and professional development. However, observing instruction, collecting data for reflection, and having conversations about teaching, are not the sole provinces of principals. Master teachers, teacher leaders, and teacher colleagues can also benefit from the supervisory sections of the book, especially the chapters on high-quality instruction, improving instruction, and the classroom data collecting tools. The book provides numerous tools specifically designed to collect a variety of data in classrooms to improve instruction. Embedded in each chapter are exercises to apply Theory into Practice by responding to a set of questions posed by the key issues of the chapter. After the explication and illustration of the key concepts and principles of the chapter, actual Instructional Leadership Challenges as described by a successful practicing principal for reflection and analysis.

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Page Count

418

Publisher

IAP

Published Date

ISBN 10

1641131683

ISBN 13

9781641131681

Managing the Drug Discovery Process

Insights and advice for students, educators, and practitioners

By: Susan Miller,Walter Moos,Barbara Munk,Stephen Munk,Charles Hart,David Spellmeyer

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Managing the Drug Discovery Process

Insights and advice for students, educators, and practitioners

By: Susan Miller,Walter Moos,Barbara Munk,Stephen Munk,Charles Hart,David Spellmeyer

Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters

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Page Count

684

Publisher

Elsevier

Published Date

ISBN 10

0128243058

ISBN 13

9780128243053

Pharmacology in Rehabilitation, Updated 5th Edition

By: Charles D. Ciccone

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Pharmacology in Rehabilitation, Updated 5th Edition

By: Charles D. Ciccone

Up-to-date, must-know coverage Bring your understanding of the rapidly evolving world of pharmacological agents and their impact on rehabilitation up to date with the Updated 5th Edition of this groundbreaking reference. An easy-to-understand writing style and easy-to-follow design help you to understand the what, why, and how of this complex subject to ensure the most effective plans of care for your patients.

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Page Count

1559

Publisher

F.A. Davis

Published Date

ISBN 10

1719645353

ISBN 13

9781719645355

The New Mind-Body Science of Depression

By: Vladimir Maletic,Charles Raison

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The New Mind-Body Science of Depression

By: Vladimir Maletic,Charles Raison

The scientific and therapeutic implications of a new way of understanding a common disease. Depression has often been studied, but this multifaceted disease remains far from understood. Here, leading researchers present a major new view of the disorder that synthesizes multiple lines of scientific evidence from neurobiology, mindfulness, and genetics. A comprehensive mind-body approach to understanding, evaluating, and treating this disease.

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461

Publisher

W. W. Norton & Company

Published Date

ISBN 10

0393708608

ISBN 13

9780393708608

Pharmacology in Rehabilitation

By: Charles D Ciccone

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Pharmacology in Rehabilitation

By: Charles D Ciccone

For more than 25 years, Dr. Charles Ciccone has been the forerunner in helping physical therapists explore how medications affect patient rehabilitation. And he’s been updating his text ever since to make sure you stay on the brink of science and innovation as drug changes occur every day and expectations for your role continually evolve. With the 5th Edition, you’ll find even more case studies, review questions, information on vitamins and supplements, and expanded coverage of chemotherapy and cancer treatments.

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736

Publisher

F.A. Davis

Published Date

ISBN 10

0803642083

ISBN 13

9780803642089

The Mysterious Commonplace

A Life in Science

By: Charles Delisi

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The Mysterious Commonplace

A Life in Science

By: Charles Delisi

Acclaimed biomedical scientist Charles DeLisi tells the story of the rewards and frustrations of a life in science, informed and influenced by a passion for poetry. The memoir spans half a century beginning in grade school when we find a painfully shy boy deeply affected by the profoundly saddening sight of trees and woods in his beloved Bronx neighborhood being displaced by tons of steel and concrete. The reader is taken inside the mind of a complex non-conformist as he struggles with personal tragedy and ambivalence and moves from physics to history back to physics, and eventually into a career as a biomedical scientist. Among the most important parts of the memoir are his personal recollections of the years as director of the Department of Energy's Health and Environmental Programs when he fought the mighty battles that would move two Federal Agencies and place the Human Genome Project, including a unique ethical component, on the National Agenda. We watch an uncannily successful strategist and leader - who sees himself as an ordinary person, distinguished only by an intense passion for science - as he and his colleagues successfully engage Congressmen, his superiors at the DOE, and scientists of different backgrounds. The story closes where it began, with environmental change dominating the emotional landscape, as he and his colleagues struggle to fight the battle against a changing climate"--

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221

Published Date

ISBN 10

9811238464

ISBN 13

9789811238468

Genome Informatics 2009

Proceedings of the 9th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2009) : Boston University, Boston, USA, 27-29 July 2009

By: Charles DeLisi

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Genome Informatics 2009

Proceedings of the 9th Annual International Workshop on Bioinformatics and Systems Biology (IBSB 2009) : Boston University, Boston, USA, 27-29 July 2009

By: Charles DeLisi

Umbilical cord blood, previously discarded after birth, has emerged over recent years as an alternative source of hematopoietic stem cells for hematological reconstitution, mainly for leukemia patients, as well as for some hematological deficiencies and bone marrow failures. In recent years, it has become increasingly clear that cord blood, as well as the surrounding tissue of the umbilical cord, contain additional stem cells which have been shown to be of great potential for regenerative medicine. Importantly, cord blood is abundant, it can be banked and shipped with ease, and thus has an indisputable potential for future medicines and regenerative therapies. Driven by a massive interest for regenerative medicine and alternative yet ethically acceptable stem cell sources, the scientific literature on umbilical cord and cord blood stem cells has increased tremendously. This book provides a consolidated, up-to-date overview of basic research on hematopoietic and mesenchymal stem cells contained within umbilical cord tissue, as well as other more recently described stem and precursor cells of not yet fully elucidated potential. It also takes an in-depth look at basic and translational research efforts with stem cells from the umbilical cord in academic institutions and biotech companies. Suitable for use as a primer and reference book by medical fellows and researchers entering the research fields of stem cell biology and regenerative medicine, it can also be used by students (undergraduate and graduate) as a starting point for read-up on the literature on stem cells and their potential and applications, or as a teaching tool in graduate schools for biologists, particularly for students wanting to enter the emerging field of stem cell biology.

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Page Count

215

Publisher

World Scientific

Published Date

ISBN 10

1848165692

ISBN 13

9781848165694

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