The captivating story of Hamilton and Madison fighting the odds to forge a nation's legacy Seven years after the revolution, America was in crisis. The government didn't work, but the citizens didn't care—or were in a state of rebellion. Then two unknown men, Hamilton and Madison (unknown especially compared to the revered Founding Fathers), envisioned a plan that no one else thought could happen: a truly United States. Against all odds, these men maneuvered and strategized to get the right men to agree on the right ideas. The result: the most brilliant political document ever, and a powerful United States. From New York Times bestselling author Charles Cerami, this gripping tale of young men founding a nation will captivate both history buffs and those who just love a great story. "Cerami spins a good historical tale." —Kirkus Reviews
In Called to Serve, founding director Charles F. Hermann and writer Sally Dee Wade chronicle the twenty-year history of the George Bush School of Government and Public Service, which has rapidly evolved into one of the nation’s major professional graduate schools of public and international affairs. The story traces the progress of the Bush School from its initial challenges to secure funding, students, and professors to its departure from the College of Liberal Arts as an independent unit with its own dean and faculty, and through the creation of its current curricula and policy-oriented research institutes. Insider stories and candid photographs illustrate how President Bush’s focused personal interest and involvement with the school and its students have contributed to the many developments and successes that the Bush School has enjoyed. With carefully researched narrative and absorbing, behind-the-scenes details, Called to Serve documents the first two decades of the Bush School’s brief but significant history and looks to the promising future that awaits this widely respected academic enterprise.
The vast array of libraries in the world bear mute witness to the truth of the 3000-year-old observation of King Solomon who stated " ... of making many books there is no end, and much study is a weariness of the flesh." Yet books are an essential written record of our lives and the progress of science and humanity. Here is another book to add to this huge collection, but, hopefully, not just another collection of pages, but rather a book with a specific purpose to aid in alleviating the "weariness of the flesh" that could arise from much studying of other journals and books in order to obtain the basic information contained herein. This book is about polymeric materials and biological activity, as the title notes. Polymeric materials, in the broad view taken here, would include not only synthetic polymers (e.g., polyethylene, polyvinyl chloride, polyesters, polyamides, etc.), but also the natural macromolecules (e.g., proteins, nucleic acids, polysaccharides) which compose natural tissues in humans, animals and plants. In the broad sense used here, biological activity is any type of such action whether it be in medication, pest control, plant-growth regu lation, and so on. In short, this book attempts to consider, briefly, the use of any type of polymeric material system with essentially any kind of biological activity.
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia the Americas.Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard.Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice.
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today’s new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard. Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia, and the Americas. Make the best use of new technologies with expanded and updated coverage of optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging. Apply the latest knowledge on anti-VEGF therapy for age related macular degeneration, diabetic retinopathy and vein disease. Learn about artificial vision, drug delivery to the posterior segment, advances in macular surgery, vitrectomy, and complex retinal detachment, with updates on tumors, retinal genetics, cell biology, important basic science topics, and much more. Get the most out of new pharmacologic approaches in the management of age-related macular degeneration and diabetic retinopathy. In your practice, diagnostic evaluations, and now even treatments, will be influenced by recent scientific discoveries such as in the areas of nanotechnology, neuro protection, stem cells and gene therapy, among other scientific contributions. View videos of surgical procedures and access the complete contents of Retina, 5th Edition online at www.expertconsult.com, fully searchable, with regular updates and a downloadable image gallery.
Following the fall of Rome, the sea is increasingly the stage upon which the human struggle of western civilization is played out. In a world of few roads and great disorder, the sea is the medium on which power is projected and wealth sought. Yet this confused period in the history of maritime warfare has rarely been studied it is little known and even less understood. Charles Stanton uses an innovative and involving approach to describe this fascinating but neglected facet of European medieval history. He depicts the development of maritime warfare from the end of the Roman Empire to the dawn of the Renaissance, detailing the wars waged in the Mediterranean by the Byzantines, Muslims, Normans, Crusaders, the Italian maritime republics, Angevins and Aragonese as well as those fought in northern waters by the Vikings, English, French and the Hanseatic League. This pioneering study will be compelling reading for everyone interested in medieval warfare and maritime history.
This Classic edition includes a new appendix which summarizes the major developments since the book was originally published in 1974. The additions are organized in short sections associated with each chapter. An additional 230 references have been added, bringing the bibliography to over 400 entries. Appendix C has been edited to reflect changes in the associated software package and software distribution method.
Tracing the development of some of the earliest and key civilizations in history, Early Civilisations of the Old World explains how particular forms of social structure and cultural interaction developed from before the Neolithic period.
Extracellular Matrix Genes provides some of the interesting complexities of the structure of the entire family of extracellular matrix genes. This book illustrates the permanent role that molecular biology and molecular genetics play in the detailed understanding of the normal biology of extracellular matrix. Organized into 10 chapters, this book begins with an overview of the structural and sequence aspects of the entire family of genomic sequences with a view to establishing common functional domains among collagens and their genes. This text then examines the status of the literature concerning human types. III and V. Other chapters consider the FACIT collagen gene family. This book discusses as well the development in understanding the structure of small proteoglycan core proteins and their role in proteoglycan biosynthesis and function as a result of their molecular cloning and expression. The final chapter deals with mutations in collagen genes. This book is a valuable resource for biochemists.
This encyclopedia provides the most complete treatment to date of the accomplishments of African American scientists—and the struggles of African Americans to find their place in the scientific community. This comprehensive reference work sheds new light on an aspect of African American life that is often overlooked. More than a summary of individuals and accomplishments, African Americans in Science: An Encyclopedia of People and Progress explores the entire experience of African Americans seeking a place in the scientific community—not just the triumphs but the frustrations, discriminations, and the efforts to support (and sometimes impede) African American scientists. African Americans in Science offers alphabetically organized entries in three areas: the contributions of African Americans in over 30 different fields of science and medicine, schools and organizations that played a role in the development of African American scientists, and additional topics related to African American scientists. No other reference offers such a complete and up-to-date portrait of the pivotal work of African Americans across the spectrum of scientific research and what it took to achieve it.
The Toughest Show on Earth is the ultimate behind-the-scenes chronicle of the divas and the dramas of New York’s Metropolitan Opera House, by the remarkable man who rose from apprentice carpenter to general manager. Joseph Volpe gives us an anecdote-filled tour of more than four decades at the Met, an institution full of vast egos and complicated politics. With stunning candor, he writes about the general managers he worked under, his embattled rise to the top, the maneuverings of the blue-chip board, and his masterful approach to making a family of such artist-stars as Luciano Pavarotti, Placido Domingo, Teresa Stratas, and Renee Fleming, and such visionary directors as Franco Zeffirelli, Robert Wilson, and Julie Taymor. Intimate and frank, The Toughest Show on Earth is not only essential for music lovers, but for anyone who wants to understand the inner workings of the culture business.
This handbook features wide ranging coverage of all the sights, from the elegant Budapest to the villages of the Northern Uplands and the historical towns of the Danube Bend. It includes practical advice on exploring the great outdoors, such as tips on cruising the Danube, hiking in the hills and horse-riding on the Great Plain, plus the lowdown on where to sample the country's famous wines.
The Historical Dictionary of Holocaust Cinema examines the history of how the Holocaust is presented in film, including documentaries, feature films, and television productions. It contains a chronology of events needed to give the films and their reception a historical contex...
The BIM Handbook is an extensively researched and meticulously written book, showing evidence of years of work rather than something that has been quickly put together in the course of a few months. It brings together most of the current information about BIM, its history, as well as its potential future in one convenient place, and can serve as a handy reference book on BIM for anyone who is involved in the design, construction, and operation of buildings and needs to know about the technologies that support it. The need for such a book is indisputable, and it is terrific that Chuck Eastman and his team were able to step up to the plate and make it happen. Thanks to their efforts, anyone in the AEC industry looking for a deeper understanding of BIM now knows exactly where to look for it." AECbytes book review, August 28, 2008 (www.aecbytes.com/review/2008/BIMHandbook.html) DISCOVER BIM: A BETTER WAY TO BUILD BETTER BUILDINGS Building Information Modeling (BIM) offers a novel approach to design, construction, and facility management in which a digital representation of the building process is used to facilitate the exchange and interoperability of information in digital format. BIM is beginning to change the way buildings look, the way they function, and the ways in which they are designed and built. The BIM Handbook, Second Edition provides an in-depth understanding of BIM technologies, the business and organizational issues associated with its implementation, and the profound advantages that effective use of BIM can provide to all members of a project team. Updates to this edition include: Completely updated material covering the current practice and technology in this fast-moving field Expanded coverage of lean construction and its use of BIM, with special focus on Integrated Project Delivery throughout the book New insight on the ways BIM facilitates sustainable building New information on interoperability schemas and collaboration tools Six new case studies Painting a colorful and thorough picture of the state of the art in building information modeling, the BIM Handbook, Second Edition guides readers to successful implementations, helping them to avoid needless frustration and costs and take full advantage of this paradigm-shifting approach to construct better buildings that consume fewer materials and require less time, labor, and capital resources.
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Variability in pathogenesis and complex pathophysiology often delay diagnosis and create significant challenges for clinical studies in this group of critically ill patients. Mainly for those reasons, there is no therapy approved so far to overcome the underlying immune dysregulation. This book provides an overview about the state of the art of sepsis diagnostics and potential future therapies. Chapter 1 focuses on the immunologic staging of sepsis—the key for successful treatment of the dysregulated hot response. Chapter 2 reveals similarities in the immune response in sepsis and cancer—opening new avenues for novel therapies. Chapter 3 introduces an important modulator of the immune response—the endogenous cannabinoid system and elucidates its role in organ dysfunction in sepsis. Facing the increasing bacterial resistance to classical antibiotics, Chapter 4 discusses two unique mechanisms to treat infection and inflammation in sepsis: iron chelation, and the sphingosine pathway. The authors, all experts in experimental and clinical sepsis research, seek to provide further understanding of the complexities of the immune response as the physiological basis for the development of new therapeutics in sepsis.
This book addresses possible analogies between cancer and developmental biology. An international group of experts provides a multidisciplinary approach, allowing biological or clinical scientists involved with cancer research to integrate specific information from diverse areas. Five concepts of cancer are presented, and developmental biology is reviewed at five levels. These are integrated in discussions of failure in organisation as a basis of cancer and its control. The book will be a valuable reference for both newcomers as well as experienced biological and clinical scientists. Features
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