Provides comprehensive coverage you need to understand, diagnose, and manage the ever-changing, high-risk clinical problems caused by pediatric infectious diseases.
This accessible approach to set theory for upper-level undergraduates poses rigorous but simple arguments. Each definition is accompanied by commentary that motivates and explains new concepts. A historical introduction is followed by discussions of classes and sets, functions, natural and cardinal numbers, the arithmetic of ordinal numbers, and related topics. 1971 edition with new material by the author"--
Mental health professionals often must make judgments or decisions involving vital matters. Is an individual likely to act violently? Has a child been sexually abused? Is a police officer fit to carry a gun? An explosion of research in clinical and cognitive psychology provides practical means for enhancing the accuracy of clinical decision making and prediction and thereby improving outcomes and the quality of care. Unfortunately, this research has not been broadly disseminated in the mental health field. The book is designed to familiarize readers with essential findings from decision science and its practical, immediate applications in the mental health field.
Integrated Lasers on Silicon provides a comprehensive overview of the state-of-the-art use of lasers on silicon for photonic integration. The authors demonstrate the need for efficient laser sources on silicon, motivated by the development of on-board/on-chip optical interconnects and the different integration schemes available. The authors include detailed descriptions of Group IV-based lasers, followed by a presentation of the results obtained through the bonding approach (hybrid III-V lasers). The monolithic integration of III-V semiconductor lasers are explored, concluding with a discussion of the different kinds of cavity geometries benchmarked with respect to their potential integration on silicon in an industrial environment. - Features a clear description of the advantages, drawbacks, and challenges of laser integration on silicon - Serves as a staple reference in the general field of silicon photonics - Focuses on the promising developments of hybrid and monolithic III-V lasers on silicon, previously unreviewed - Discusses the different kinds of cavity geometries benchmarked with respect to their potential integration on silicon in an industrial environment
The erosion of its competitiveness is raising concerns about the sustainability of Bangladesh's growth model based on exports of ready-made garments. To safeguard its comparative advantage in ready-made garments and diversify its exports basket, Bangladesh needs to increase its competitiveness. Improving logistics performance is an important lever with which to do so. Moving Forward: Connectivity and Logistics to Sustain Bangladesh's Success presents a comprehensive assessment of logistics performance and its main determinants. It analyzes freight demand at a spatially disaggregated level, quantifies logistics costs, including the costs of externalities, looks at the factors that determine the stock and quality of infrastructure, and examines the incentives to provide logistics services of a certain type and quality and to charge the observed prices. It also quantifies the potential impacts of removing transport and logistics inefficiencies on Bangladesh's exports and economic geography using a spatial general equilibrium model. Bangladesh's congested, unreliable, and unsophisticated logistics system imposes high costs on the economy. Making it efficient requires a holistic system-wide approach that is based on a comprehensive strategy; improves the quality, capacity, and management of infrastructure; improves the quality and integration of logistics services; and achieves seamless regional connectivity. Moving Forward will be of interest to policy makers, private sector practitioners, and academics with an interest in the performance of Bangladesh's transport and logistics sectors.
Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
For more than 60 years, Shackelford's Surgery of the Alimentary Tract has served as the cornerstone reference in this fast-moving field. With comprehensive coverage of all aspects of GI surgery, the 8th Edition, by Drs. Charles J. Yeo, Steven R. DeMeester, David W. McFadden, Jeffrey B. Matthews, and James W. Fleshman, offers lavishly illustrated, authoritative guidance on endoscopic, robotic, and minimally invasive procedures, as well as current medical therapies. Each section is edited by a premier authority in GI surgery; chapters reflect key topics and are written by a "who's who" of international experts in the field. It's your one-stop resource for proven, systematic approaches to all relevant adult and pediatric GI disorders and operations - Features an abundance of beautifully detailed intraoperative and laparoscopic photographs, as well as radiographs and line drawings, to enhance and clarify the text. - Presents essential information, such as lists of differential diagnoses, in tabular format for quick reference. - Discusses recent, major advances in minimally invasive surgery and robotic surgery, personalized therapy based on genomics and proteomics, and new pharmacologic treatments of various GI diseases. - Includes all-new information on laparoscopy for rectal cancer, sacral nerve stimulation for incontinence and constipation, management of Crohn's disease and ulcerative colitis, advances in immunosuppression for transplant patients, and new therapies for inflammatory bowel disease. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Need the go-to reference on adult bone and joint injuries? Get the definitive guide on fracture treatment, written by the world’s top orthopaedic surgeons: Rockwood and Green’s Fractures in Adults. This fully updated and expanded 8th edition offers up-to-the-minute research and recommendations from more than 80 leading orthopaedic experts from around the world. An essential resource on fractures for every orthopaedic surgeon or resident.. Features: NEW chapters on: Management of the Geriatric or Elderly Patient; Management of Bone Defects;; Psychological Aspect of Trauma NEW authors from countries including India, China, Columbia, Greece, and Denmark NEW 10 new full length videos added to the video library. All videos feature easy navigation so you can go directly to specific steps in the procedure, or watch the entire procedure from start to finish Pearls and Pitfalls and preventive measures listed for all procedures NEW Time-saving outline template for easy quick-reference “Before the Case” checklists of all necessary equipment for each surgical procedure Preferred Technique section provides algorithms explaining each author’s choice of preferred procedure Full-color operative photos, tables, x-rays, diagrams, and more than 500 line drawings of surgical procedures
Modern electronics testing has a legacy of more than 40 years. The introduction of new technologies, especially nanometer technologies with 90nm or smaller geometry, has allowed the semiconductor industry to keep pace with the increased performance-capacity demands from consumers. As a result, semiconductor test costs have been growing steadily and typically amount to 40% of today's overall product cost. This book is a comprehensive guide to new VLSI Testing and Design-for-Testability techniques that will allow students, researchers, DFT practitioners, and VLSI designers to master quickly System-on-Chip Test architectures, for test debug and diagnosis of digital, memory, and analog/mixed-signal designs. - Emphasizes VLSI Test principles and Design for Testability architectures, with numerous illustrations/examples. - Most up-to-date coverage available, including Fault Tolerance, Low-Power Testing, Defect and Error Tolerance, Network-on-Chip (NOC) Testing, Software-Based Self-Testing, FPGA Testing, MEMS Testing, and System-In-Package (SIP) Testing, which are not yet available in any testing book. - Covers the entire spectrum of VLSI testing and DFT architectures, from digital and analog, to memory circuits, and fault diagnosis and self-repair from digital to memory circuits. - Discusses future nanotechnology test trends and challenges facing the nanometer design era; promising nanotechnology test techniques, including Quantum-Dots, Cellular Automata, Carbon-Nanotubes, and Hybrid Semiconductor/Nanowire/Molecular Computing. - Practical problems at the end of each chapter for students.
For nearly 60 years, Heptinstall’s Pathology of the Kidney has been the reference of choice for both pathologists and nephrologists for expert, authoritative coverage of kidney disease. The fully revised and reorganized Eighth Edition, edited by Drs. J. Charles Jennette, Vivette D. D’Agati, Agnes B. Fogo, Volker Nickeleit and Michael Barry Stokes offers thorough pathologic descriptions, important clinical correlations, and up-to-date discussions of causes and pathogenesis to improve understanding of kidney disease and to facilitate accurate diagnosis and optimum care of patients with kidney disease. Now in a single volume, this image-rich text conveys the unique challenges and intricacies of renal disease, offering powerful diagnostic and treatment recommendations from decades of clinical research.
The Genesis of East Asia examines in a comprehensive and novel way the critically formative period when a culturally coherent geopolitical region identifiable as East Asia first took shape. By sifting through an impressive array of both primary material and modern interpretations, Charles Holcombe unravels what “East Asia” means, and why. He brings to bear archaeological, textual, and linguistic evidence to elucidate how the region developed through mutual stimulation and consolidation from its highly plural origins into what we now think of as the nation-states of China, Japan, Korea, and Vietnam. Beginning with the Qin dynasty conquest of 221 B.C. which brought large portions of what are now Korea and Vietnam within China’s frontiers, the book goes on to examine the period of intense interaction that followed with the many scattered local tribal cultures then under China’s imperial sway as well as across its borders. Even the distant Japanese islands could not escape being profoundly transformed by developments on the mainland. Eventually, under the looming shadow of the Chinese empire, independent native states and civilizations matured for the first time in both Japan and Korea, and one frontier region, later known as Vietnam, moved toward independence. Exhaustively researched and engagingly written, this study of state formation in East Asia will be required reading for students and scholars of ancient and medieval East Asian history. It will be invaluable as well to anyone interested in the problems of ethno-nationalism in the post-Cold War era.
Originally published in 1977. Management is a dynamic process reflected in three essential functions: management of time, change and people. The book provides a bridging gap between quantitative theories imbedded in the systems approach and managerial decision-making over time and under risk. The conventional wisdom that management is a dynamic process is rendered operational. This title will be of interest to students of business studies and management.
Covering everything from preoperative evaluation to neonatal emergencies to the PACU, A Practice of Anesthesia in Infants and Children, 6th Edition, features state-of-the-art advice on the safe, effective administration of general and regional anesthesia to young patients. It reviews underlying scientific information, addresses preoperative assessment and anesthesia management in detail, and provides guidelines for postoperative care, emergencies, and special procedures. Comprehensive in scope and thoroughly up to date, this 6th Edition delivers unsurpassed coverage of every key aspect of pediatric anesthesia. - Includes a laminated pocket reference guide inside with essential, practical information. - Features key references at the end of each chapter that provide a quick summary for review. - Presents must-know information on standards, techniques, and the latest advances in pediatric anesthesia from global experts. - Provides access to a video library of 70 pediatric anesthesia procedures – 35 are new! Videos include demonstrations on managing the difficult pediatric airway, cardiac assist devices in action, new positioning devices, management of burn injuries, and many demonstrations of ultra-sound guided regional anesthesia blocks and techniques. - Features extensive revisions of all chapters with many new contributors, and numerous new figures and tables throughout. - Introduces new drugs such as those used to premedicate children and facilitate emergence from anesthesia, plus an up-to-date discussion of the drug approval process and detailed information on opioid safety for children with obstructive sleep. - Includes new chapters on pharmacogenomic implications of drugs in children and the anesthetic implications when caring for children with cancer. - Offers up-to-date information on the management of emergence agitation, sleep-disordered breathing, neonatal and pediatric emergencies, and the obese child and bariatric surgery. - The Essentials chapters, with extensive input from pediatrician experts, provide the latest information concerning hematology, pulmonology, oncology, hepatology, nephrology, and neurology. - Contains significant updates on perioperative fluid management, pharmacology, intravenous anesthesia and target controlled infusions, cystic fibrosis, new interventional devices for children with congenital heart defects, cardiopulmonary resuscitation, simulation in pediatric anesthesia, and much more. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Presents an integrated view of the expression of bacterial genetic information, genome architecture and function, and bacterial physiology and pathogenesis This book blends information from the very latest research on bacterial chromosome and nucleoid architecture, whole-genome analysis, cell signaling, and gene expression control with well-known gene regulation paradigms from model organisms (including pathogens) to give readers a picture of how information flows from the environment to the gene, modulating its expression and influencing the competitive fitness of the microbe. Structure and Function of the Bacterial Genome explores the governance of the expression of the genes that make a bacterium what it is, and updates the basics of gene expression control with information about transcription promoter structure and function, the role of DNA as a regulatory factor (in addition to its role as a carrier of genetic information), small RNAs, RNAs that sense chemical signals, ribosomes and translation, posttranslational modification of proteins, and protein secretion. It looks at the forces driving the conservation and the evolution of the dynamic genome and offers chapters that cover DNA replication, DNA repair, plasmid biology, recombination, transposition, the roles of repetitive DNA sequences, horizontal gene transfer, the defense of the genome by CRISPR-Cas, restriction enzymes, Argonaute proteins and BREX systems. The book finishes with a chapter that gives an integrated overview of genome structure and function. Blends knowledge of gene regulatory mechanisms with a consideration of nucleoid structure and dynamics Offers a 'DNA-centric' approach to considering transcription control Views horizontal gene transfer from a gene regulation perspective Assesses the opportunities and limitations of designing synthetic microbes or rewiring existing ones Structure and Function of the Bacterial Genome is an ideal book for graduate and undergraduate students studying microbial cell biology, bacterial pathogenesis, gene regulation, and molecular microbiology. It will also appeal to principal investigators conducting research on these and related topics and researchers in synthetic biology and other arms of biotechnology.
This book presents new information on radiobiology that more clearly refutes the linear no-threshold (LNT) assumption and supports radiation hormesis. Fresh light is cast on the mechanisms of radiation hormesis and the potential benefits of low-dose ionizing radiation in preventing and treating a wide variety of inflammatory and proliferative diseases. It is proposed that these effects may derive from cellular communication via electromagnetic waves directed by DNA, with each cell acting as a quantum computer. Readers will also find close analysis of the negative impacts of radiophobia on many aspects of modern life, including attitudes to imaging technologies, licensing of nuclear power reactors, and preparedness for survival of nuclear war. The book will be of interest to researchers and scientists in radiobiology, radiation protection, health physics, medical physics, and radiology. Specifically, it will provide medical physicians, radiation oncologists, radiation epidemiologists, gerontologists, cell biologists, toxicologists, and nuclear engineers with a wide range of interesting facts and enlightening novel perspectives.
This book contains papers on algebra, functional analysis, and general topology, with a strong interaction with set theoretic axioms and involvement with category theory, presented in the special session on Rings of Continuous Functions held in 1982 in Cincinnati, Ohio.
This International Conference is about sustainability in its wider sense. It is an important area of discourse, as it pertains to how we work and how we lead our lives while considering the lives and workplaces of future generations. The conference particularly sets out to explore some of the developments and challenges taking place in academia and industry in both the Northern and Southern hemispheres. The conference is entitled "Going north for sustainability". The North signifies progress in technology, education and other areas of human endeavour to many people. Progress requires that people learn across continents and cultures.
In 1763, Reverend Edmund Stone took the first step toward the discovery of one of the most commonly used medicines when he noted that the bark of the English willow was an effective treatment for patients suffering from a fever. This synthesised compound would eventually become known as one of the most prescribed drugs for acute and chronic pain symptoms. However, through years of trial and error, this drug has been the subject of many controversial issues. Aspirin serves as one of the leading agents for cardiovascular treatment in women. However, many patients have experienced negative side effects of internal bleeding and lining damage due to strong amounts of acid in the drug. Aspirin is often effective when taken in small doses. This book brings together medical and biological research. These involve neurological effects, clinical and experimental reactions, lung exposure, withdrawal symptoms, cardiovascular side effects, uses in cancer treatment and many other application areas.
Bioprocess technology involves the combination of living matter (whole organism or enzymes ) with nutrients under laboratory conditions to make a desired product within the pharmaceutical, food, cosmetics, biotechnology, fine chemicals and bulk chemicals sectors. Industry is under increasing pressure to develop new processes that are both environmentally friendly and cost-effective, and this can be achieved by taking a fresh look at process development; - namely by combining modern process modeling techniques with sustainability assessment methods. Development of Sustainable Bioprocesses: Modeling and Assessment describes methodologies and supporting case studies for the evolution and implementation of sustainable bioprocesses. Practical and industry-focused, the book begins with an introduction to the bioprocess industries and development procedures. Bioprocesses and bioproducts are then introduced, together with a description of the unit operations involved. Modeling procedures, a key feature of the book, are covered in chapter 3 prior to an overview of the key sustainability assessment methods in use (environmental, economic and societal). The second part of the book is devoted to case studies, which cover the development of bioprocesses in the pharmaceutical, food, fine chemicals, cosmetics and bulk chemicals industries. Some selected case studies include: citric acid, biopolymers, antibiotics, biopharmaceuticals. Supplementary material provides hands-on materials so that the techniques can be put into practice. These materials include a demo version of SuperPro Designer software (used in process engineering) and models of all featured case studies, excel sheets of assessment methods, Monte Carlo simulations and exercises. Previously available on CD-ROM, the supplementary material can now be accessed via http://booksupport.wiley.com by entering the author name, book title or isbn and clicking on the desired entry. This will then give a listing of all the content available for download. Please read any text files before downloading material.
Get the core knowledge in pain medicine you need from one of the most trusted resources in the field. The new fourth edition guides you through every aspect of pain medicine with concise descriptions of evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. From commonly seen pain syndromes, including headaches, trunk pain, orofacial pain, back pain, and extremity pain...through specific pain management challenges such as postoperative pain, pain due to cancer, phantom pain, and pain in the management of AIDS patients...this popular text will equip you with the know-how you need to effectively manage even your most challenging cases. A practical, multidisciplinary approach to pain management makes key concepts and techniques easier to apply to everyday practice. Expert contributors provide the latest knowledge on all aspects of pain management, from general principles through to specific management techniques. Detailed discussions of the latest concepts and treatment plans help you provide the best possible outcomes for all your patients. Extensively updated chapters acquaint you with the most current trends and techniques in pain management. A new section on complications helps you avoid and manage potential pitfalls. A new editorial team ensures that you are getting the freshest, most clinically relevant information available today. New, full-color art clarifies key concepts and techniques.
First truly up-to-date treatment offers a simple introduction to optimal control, linear-quadratic control design, and more. Broad perspective features numerous exercises, hints, outlines, and appendixes, including a practical discussion of MATLAB. 2005 edition.
Charles Babbage (1792–1871) articulated the principles behind modern computing machines. This compilation of his writings, plus those of several of his contemporaries, illuminates the early history of the calculator.
This updated introduction to modern numerical analysis is a complete revision of a classic text originally written in Fortran but now featuring the programming language C++. It focuses on a relatively small number of basic concepts and techniques. Many exercises appear throughout the text, most with solutions. An extensive tutorial explains how to solve problems with C++.
Collection of nearly 200 unusual problems dealing with congruence and parallelism, the Pythagorean theorem, circles, area relationships, Ptolemy and the cyclic quadrilateral, collinearity and concurrency and more. Arranged in order of difficulty. Detailed solutions.
Interfacing physics and electrical engineering, this graduate-level text reveals the inherent simplicity of the basic ideas of electromagnetic wave propagation and antennas and their logical development from Maxwell field equations. Topics include radiation from monochromatic sources in unbounded regions, electromagnetic waves in a plasma medium, Doppler effect, much more. 1965 edition.
The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology.
Imaging of the Spine—an exhaustive, full-color reference—combines the ease of use of an atlas with the comprehensive coverage of a definitive reference work. Renowned experts Drs. Thomas P. Naidich, Mauricio Castillo, Charles Raybaud, James G. Smirniotopoulos, Soonmee Cha, and Spyros Kollias cover every aspect of spine imaging, including the latest diagnostic modalities, interventional techniques, and image-guided procedures through over 1300 digital quality illustrations. - View 1300 digital quality images of both radiographic images and cutting edge modalities—MR, multislice CT, ultrasonography, and nuclear medicine. - Consult the expertise of a diverse group of experts from around the globe on the imaging of the spine. - Tap into comprehensive coverage that includes diagnostic and therapeutic options, with an emphasis on cost-effective imaging. - Find information quickly and easily thanks to consistent and tightly focused chapters, a full color design, and key points boxes.
Praised by JAMA as "The most complete description of the development, structure, function, pathophysiology, and treatment of the retina and its diseases to be found anywhere," this monumental three-volume work puts all of today's scientific and clinical knowledge of the retina at readers' fingertips. The New Edition has been comprehensively updated and reorganized to reflect all of the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques. The result is an indispensable reference and diagnostic tool for generalists and specialists alike. Delivers the editorial expertise of four highly respected authorities, as well as contributions from internationally recognized leaders in visual science, ophthalmology, and vitreoretinal studies. Presents more than 3,400 superb illustrations (2,200 in full color) that capture all forms of retinal disease from every perspective. Offers the very latest information on the genetic basis of retinal disease, diagnostic retinal imaging, photodynamic therapy, and age-related macular degeneration. Examines the most recent advances in diagnostic indocyanine green angiography � optical coherence tomography (OCT) and quantitative fluoroscein angiography � macular translocation with 360� peripheral retinectomy � surgery for diffuse macular edema due to multiple causes, including proliferative vitreoretinopathy � artificial vision � and much more. Features a completely restructured section on age-related macular degeneration that includes epidemiology and risk factors � prophylaxis and prevention knowledge gained from large clinical trials like AREDS � proven and experimental treatments for AMD � and pharmacotherapy. Incorporates a multitude of new full-color images, 2200 in all.
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today’s new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard. Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia, and the Americas. Make the best use of new technologies with expanded and updated coverage of optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging. Apply the latest knowledge on anti-VEGF therapy for age related macular degeneration, diabetic retinopathy and vein disease. Learn about artificial vision, drug delivery to the posterior segment, advances in macular surgery, vitrectomy, and complex retinal detachment, with updates on tumors, retinal genetics, cell biology, important basic science topics, and much more. Get the most out of new pharmacologic approaches in the management of age-related macular degeneration and diabetic retinopathy. In your practice, diagnostic evaluations, and now even treatments, will be influenced by recent scientific discoveries such as in the areas of nanotechnology, neuro protection, stem cells and gene therapy, among other scientific contributions. View videos of surgical procedures and access the complete contents of Retina, 5th Edition online at www.expertconsult.com, fully searchable, with regular updates and a downloadable image gallery.
Still the most comprehensive reference available on surgical flaps, this classic text remains your go-to source for practical, authoritative guidance on achieving the best possible outcomes for your patients. The thoroughly revised 4th Edition features an all-new, full-color format that greatly enhances its visual appeal and usefulness in your everyday practice. Dozens of internationally recognized experts describe every clinical proven flap option available for repairing both routine and unusual problems, lavishly illustrated with clinical photographs and diagrams of anatomy, blood supply, flap design, and operative procedures. Extensively indexed and organized by anatomic region, chapters follow a logical format that clearly presents all the information you need to know: indications, anatomy, flap design and dimensions, operative technique, clincal results, and summary. This comprehensive, clinically relevant information allows you to select the best flaps for safe, predictable, and aesthetically desirable results for every patient. Volume 2 of Grabb’s Encyclopedia of Flaps, 4th Edition, covers Upper Extremities, Torso, Pelvis, and Lower Extremities. For complete coverage of every anatomic area, please order the 2-Volume set.
The Segment in Phonetics and Phonology unravels exactly what the segment is and on what levels it exists, approaching the study of the segment with theoretical, empirical, and methodological heterogeneity as its guiding principle. A deliberately eclectic approach to the study of the segment that investigates exactly what the segment is and on what level it exists Includes new research data from a diverse range of fields such as experimental psycholinguistics, language acquisition, and mathematical theories of communication Represents the major theoretical models of phonology, including Articulatory Phonology, Optimality Theory, Laboratory Phonology and Generative Phonology Examines both well-studied languages like English, Chinese, and Japanese and under-studied languages such as Southern Sierra Miwok, Päri, and American Sign Language
This exhaustive reference includes new chapters and pedagogical features, as well as—for the first time—content on managing fragility factures. To facilitate fast, easy absorption of the material, this edition has been streamlined and now includes more tables, charts, and treatment algorithms than ever before. Experts in their field share their experiences and offer insights and guidance on the latest technical developments for common orthopaedic procedures, including their preferred treatment options.
This textbook introduces research on dinosaurs by describing the science behind how we know what we know about dinosaurs. A wide range of topics is covered, from fossils and taphonomy to dinosaur physiology, evolution, and extinction. In addition, sedimentology, paleo-tectonics, and non-dinosaurian Mesozoic life are discussed. There is a special opportunity to capitalize on the enthusiasm for dinosaurs that students bring to classrooms to foster a deeper engagement in all sciences. Students are encouraged to synthesize information, employ critical thinking, construct hypotheses, devise methods to test these hypotheses, and come to new defensible conclusions, just as paleontologists do. Key Features Clear and easy to read dinosaur text with well-defined terminology Over 600 images and diagrams to illustrate concepts and aid learning Reading objectives for each chapter section to guide conceptual learning and encourage active reading Companion website (teachingdinosaurs.com) that includes supporting materials such as in-class activities, question banks, lists of suggested specimens, and more to encourage student participation and active learning Ending each chapter with a specific "What We Don’t Know" section to encourage student curiosity Related Titles Singer, R. Encyclopedia of Paleontology (ISBN 978-1-884964-96-1) Fiorillo, A. R. Alaska Dinosaurs: An Ancient Arctic World (ISBN 978-1-138-06087-6) Caldwell, M. W. The Origin of Snakes: Morphology and the Fossil Record (ISBN 978-1-4822-5134-0)
The definitive reference in the field for more than 35 years, Creasy and Resnik's Maternal-Fetal Medicine provides today's MFM practitioners with authoritative, comprehensive guidance on every aspect of this fast-changing field. The fully revised 9th Edition brings you up to date with the latest evidence-based guidelines and research as well as the fundamental scientific foundation needed for effective practice, helping you minimize complications and ensure the best possible outcomes for your patients. Renowned experts in obstetrics, gynecology, and perinatology provide valuable information in every area of complex obstetric care, highlighting the most commonly encountered anomalies and providing clear guidelines for obstetric and neonatal management. - Offers comprehensive updates on rapidly changing topics, including extensively revised genetic content throughout. - Includes two new chapters: maternal and fetal viral infections, including COVID-19; and sexually transmitted disease, covering the epidemiology, pathogenesis, diagnosis, and treatment of individual infectious diseases that may complicate pregnancy. - Contains user-friendly features such as numerous diagnostic and treatment algorithms for quick access to current protocols; key points at the end of each chapter; and counseling pearls with practical guidance on patient consultation. - Features a comprehensive imaging section, including a video library to aid in everyday diagnosis. - Shares the expertise of a renowned editorial team—including new co-editors Drs. Lorraine Dugoff and Judette M. Louis—who lead authors representing top institutions from around the globe. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
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