“A magnificent portrayal of every facet of the Cuban exile experience. Haunting short stories convey the pain, loss, longing, and courage of the exiles.” —Dan Wakefield, author of Kurt Vonnegut: The Making of a Writer Castro’s communist regime gained control of Cuba in 1959, sparking a surge of immigration to the United States, particularly Miami, as refugees sought a better life. But for many, Cuba will always be home. The island’s stories pass from refugee to refugee, immigrant to grandchild, mingling hope for the future with grief for what’s lost. Yet these stories also pass down a deep, unconscious desire for the unattainable, which often results in fractured relationships and a loss of purpose for both young and old. Grieving for Guava revels in the unbroken ties between past and future, Havana and Miami, and recounts the unintended generational costs of immigration. Ten stories explore the lives of Cuban refugees in Miami as they grapple with a longing for the past and a fervent need to move forward. Spanning six decades of the Cuban exile, these stories lay bare a collective struggle to overcome the destabilizing effects of migration and to reassemble splintered identities: A journalist returns to the island for a childhood toy. An investment banker leaves Miami to open a bookstore near the Malecon. A girl with cerebral palsy attempts to swim across the ocean to reach her lost home. Cecilia Fernandez artfully weaves together the complicated lives of her characters to produce an overarching sense of yearning for the past, transforming grief into an even more powerful force: communion. “What a lovely tribute to the author’s roots and to her tribe of early exiles!” —Mirta Ojito, author of Hunting Season
Revolution uprooted six-year-old Cecilia from her comfortable middle-class Cuban home and dropped her into the low-income neighborhood of Miami’s Little Havana. Her philandering father focused on rebuilding his career, chasing the American promise of wealth and freedom from the past. Her mother spiraled into madness trying to hold the family together and get him back. Neglected and trapped, Cecilia rebelled against her conservative culture and embraced the 1960s counter-culture - seeking love, attention and a place of her own in America. But immigrant children either thrive or self-destruct in a new land. How will Cecilia beat the odds? While most memoirs by Cuban-Americans revolve around childhood scenes in Cuba and explore the experiences of a young man, Leaving Little Havana is the first refugee memoir to focus on a Cuban girl growing up in America, rising above the obstacles and clearing a path to her American Dream. “Leaving Little Havana is the compelling story of a Cuban girl seeking a new life in the U.S. with her family as the Cuban revolution unfolds in the early sixties. 'Cecilita’s' personal account, and sexual awakening, is transparent, sad, and triumphant, sprinkled with anecdotes of an emerging Cuban-American landscape. In short, this book is a colorful reminiscence of historical scenes on both sides of the Straits of Florida, providing closure to a Cuban American journalist coming to terms with her turbulent past.” - Guarione M. Diaz, President Emeritus, Cuban American National Council “Cecilia Fernandez’s memoir of growing up Cuban in Miami is not only fascinating reading, it tells more about the story of Cubans in this U.S. than a truckload of sociology textbooks - and is a thousand times more entertaining!” - Dan Wakefield, author of New York in the Fifties “Leaving Little Havana is a candid, touching, and engaging memoir of a young Cuban exile’s coming of age. Cecilia Fernandez writes with passion and intensity, both of her missteps and her triumphs, casting fresh light on the American experience in the process.” - Les Standiford, author of Havana Run and Bringing Adam Home “Cecilia Fernandez gives us a coming of age story told with wide open eyes and vivid details of growing up in Little Havana. Broken-hearted more times than she can count, she gradually finds a path to new beginnings and the infinite promises of the American Dream. A poignant and important chronicle of the Miami Cuban immigrant journey.” - Ruth Behar, author of Traveling Heavy: A Memoir in Between Journeys “Every so often along comes a book that seizes you by the collar and arrests you on the spot. From page one, Leaving Little Havana is a brilliant, voice-driven book that will make your heart skip a few beats. My experience reading this book was similar to the first time I read The House on Mango Street by Sandra Cisneros when you instantly know you are reading a classic, a story so achingly beautiful and unforgettable you relish every last word as if it were the buzzing of a hummingbird at your lips feeding you honey. This book is about family, about what happens to family in exile, about how people come into a great world of struggle and manage to get by and survive. The author has a great gift for capturing that world-known enclave of Miami we love and call Little Havana. This might be the book that puts it on the literary map for good and forever.” - Virgil Suárez, author of Latin Jazz, The Cutter, and 90 Miles: Selected and New Poems
Revolution uprooted six-year-old Cecilia from her comfortable middle-class Cuban home and dropped her into the low-income neighborhood of Miami’s Little Havana. Her philandering father focused on rebuilding his career, chasing the American promise of wealth and freedom from the past. Her mother spiraled into madness trying to hold the family together and get him back. Neglected and trapped, Cecilia rebelled against her conservative culture and embraced the 1960s counter-culture - seeking love, attention and a place of her own in America. But immigrant children either thrive or self-destruct in a new land. How will Cecilia beat the odds? While most memoirs by Cuban-Americans revolve around childhood scenes in Cuba and explore the experiences of a young man, Leaving Little Havana is the first refugee memoir to focus on a Cuban girl growing up in America, rising above the obstacles and clearing a path to her American Dream. “Leaving Little Havana is the compelling story of a Cuban girl seeking a new life in the U.S. with her family as the Cuban revolution unfolds in the early sixties. 'Cecilita’s' personal account, and sexual awakening, is transparent, sad, and triumphant, sprinkled with anecdotes of an emerging Cuban-American landscape. In short, this book is a colorful reminiscence of historical scenes on both sides of the Straits of Florida, providing closure to a Cuban American journalist coming to terms with her turbulent past.” - Guarione M. Diaz, President Emeritus, Cuban American National Council “Cecilia Fernandez’s memoir of growing up Cuban in Miami is not only fascinating reading, it tells more about the story of Cubans in this U.S. than a truckload of sociology textbooks - and is a thousand times more entertaining!” - Dan Wakefield, author of New York in the Fifties “Leaving Little Havana is a candid, touching, and engaging memoir of a young Cuban exile’s coming of age. Cecilia Fernandez writes with passion and intensity, both of her missteps and her triumphs, casting fresh light on the American experience in the process.” - Les Standiford, author of Havana Run and Bringing Adam Home “Cecilia Fernandez gives us a coming of age story told with wide open eyes and vivid details of growing up in Little Havana. Broken-hearted more times than she can count, she gradually finds a path to new beginnings and the infinite promises of the American Dream. A poignant and important chronicle of the Miami Cuban immigrant journey.” - Ruth Behar, author of Traveling Heavy: A Memoir in Between Journeys “Every so often along comes a book that seizes you by the collar and arrests you on the spot. From page one, Leaving Little Havana is a brilliant, voice-driven book that will make your heart skip a few beats. My experience reading this book was similar to the first time I read The House on Mango Street by Sandra Cisneros when you instantly know you are reading a classic, a story so achingly beautiful and unforgettable you relish every last word as if it were the buzzing of a hummingbird at your lips feeding you honey. This book is about family, about what happens to family in exile, about how people come into a great world of struggle and manage to get by and survive. The author has a great gift for capturing that world-known enclave of Miami we love and call Little Havana. This might be the book that puts it on the literary map for good and forever.” - Virgil Suárez, author of Latin Jazz, The Cutter, and 90 Miles: Selected and New Poems
Castro's communist regime gained control of Cuba in 1959, sparking a surge of immigration to the United States, particularly Miami, as refugees sought a better life. But for many, Cuba will always be home. The island's stories pass from refugee to refugee, immigrant to grandchild, mingling hope for the future with grief for what's lost. Yet these stories also pass down a deep, unconscious desire for the unattainable, which often results in fractured relationships and a loss of purpose for both young and old. Grieving for Guava revels in the unbroken ties between past and future, Havana and Miami, and recounts the unintended generational costs of immigration. Ten stories explore the lives of Cuban refugees in Miami as they grapple with a longing for the past and a fervent need to move forward. Spanning six decades of the Cuban exile, these stories lay bare a collective struggle to overcome the destabilizing effects of migration and to reassemble splintered identities: A journalist returns to the island for a childhood toy. An investment banker leaves Miami to open a bookstore near the Malecon. A girl with cerebral palsy attempts to swim across the ocean to reach her lost home. Cecilia Fernandez artfully weaves together the complicated lives of her characters to produce an overarching sense of yearning for the past, transforming grief into an even more powerful force: communion. Grieving for Guava captures the heartache and hope that are common in the immigrant experience, adding a dynamic, human voice to the politically charged dialogue surrounding immigration.
The prevalence of obesity has over the last 40 years nearly tripled and obesity is one of the major risk factors of developing type 2 diabetes. Type 2 diabetes was formerly called adultonset diabetes but today, probably due to the rise in childhood obesity, it is also seen in children and adolescents. Type 2 diabetes is diagnosed when the body no longer can control the glucose levels in the blood. This is due to an insulin resistant state in the insulin responding tissues, liver, adipose and muscle and insufficient production of insulin in the pancreas. However, in spite of extensive research the mechanisms behind insulin resistance is still not known. The adipose tissue is believed to play a major role in the development of whole body insulin resistance. Adipocytes are the most important sites for storage of the high energy containing triacylglycerols. Insulin stimulation causes the adipocyte to increase the uptake of glucose and to reduce lipolysis: the hydrolysis of triacylglycerol and release of glycerol and fatty acids. The insulin signalling network is complex with numerous proteins involved. These signaling proteins not only transmit the insulin signal but also create negative and positive feedbackloops and induce cross talk between different parts of the network and with the signalling of other hormones. One important positive feedback in insulin signalling is the mTORC1 mediated feedback to phosphorylation of IRS1 at serine 307. In paper I we found that in human adipocytes this feedback is not likely catalysed by the assumed kinase S6K1. However we find an immunoprecipitate of mTOR to contain a ser307 phosphorylating kinase. Scaffolding proteins serve as docking sites for several proteins to promote protein-protein interactions that facilitate signal transduction. In paper II we demonstrate the existence of the scaffolding protein IQGAP1 in human adipocytes and that the expression of IQGAP1 is downregulated in type 2 diabetes. We reveal that IQGAP1 co-localises with caveolae, invaginations of the plasma membrane where the insulin receptor is situated, and that this interaction is increased upon insulin stimulation. In paper III we focus on the control of lipolysis, and sought to understand the interplay between insulin and beta-adrenergic stimulation. We demonstrated that the re-esterification of fatty acids is downregulated in type 2 diabetes causing an increased release of fatty acids from the cells. We showed that beta-adrenergic stimulation with isoproterenol induced a negative feedback via PKA/Epac1 -> PI3K -> PKB -> PDE3B that reduced the cAMP levels and thereby also reduced lipolysis. We also showed that insulin, in addition to its well-known anti-lipolytic effect, at high concentrations had a positive effect on lipolysis. In conclusion we reveal an intricate control of the stimulation as well as the inhibition of lipolysis induced by both isoproterenol and insulin.
Lactose-Derived Prebiotics: A Process Perspective is the first scientific reference to provide a comprehensive technological overview of the processes to derive oligosaccharides from dairy for use in functional foods. With their combined 90+ years in industry and research, the authors present the functional properties of prebiotics derived from lactose and the production technology required to make them. The book focuses on process engineering and includes an overview of green chemistry processes involving enzyme biocatalysis, providing detailed coverage of the use of whey lactose as raw material for producing oligosaccharides. The book's focus on processes and products allows the reader to understand the constraints and impacts of technology on lactose-derived prebiotics. - Presents the challenges of and opportunities for deriving oligosaccharides from lactose - Details the technologies and methods required to produce lactose-derived prebiotics, including a comparison between chemical and enzymatic synthesis - Discusses the potential use of whey as a raw material for the synthesis of non-digestible lactose-derived oligosaccharides - Provides a process engineer perspective and includes valuable information about kinetics and reactor design for the enzymatic synthesis of lactose-derived oligosaccharides
This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding of this topic Presents fundamentals and real-world examples in a ‘learning-though-doing’ style
Placing an emphasis on global perspectives and current research, this wide praised and adopted sociology textbook introduces the reader to the field of sociology. & John Macionis, like many people, took a college course that shaped his life. His first sociology course helped him make sense of the world. John shares his enthusiasm, excitement, and teaching experience through a clear and engaging writing style and emphasis on sociology's relevance to everyday life.
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