Completely revised and updated, ERP: Tools, Techniques, and Applications for Integrating the Supply Chain, Second Edition describes, from the perspective of a business manager, concepts and tools for enterprise planning, management, and execution. The text is written in an easy-to-read format, with many real examples from a variety of industries th
Tobacco has been pervasive in China almost since its introduction from the Americas in the mid-sixteenth century. One-third of the world's smokers--over 350 million--now live in China, and they account for 25 percent of worldwide smoking-related deaths. This book examines the deep roots of China's contemporary "cigarette culture" and smoking epidemic and provides one of the first comprehensive histories of Chinese consumption in global and comparative perspective"--Provided by publisher.
A complete revision of the industry-standard book on materials requirements standards for manufacturing This fully revised and updated edition of the landmark work on material requirements planning (MRP) focuses on the new rules required to effectively support a manufacturing operation using MRP systems in the twenty-first century. You will get all-new coverage of demand-driven material requirements planning (DDMRP) along with complete implementation steps. Orlicky's Material Requirements Planning, Fourth Edition offers proven solutions that help you gain the competitive edge through strategic lead time reductions, substantial reductions in total inventory investment, and significant increases in service levels. This guide is an indispensable tool for manufacturing practitioners and anyone preparing for CPIM certification. Completely revised to follow process flow combining MRP, MRPII, ERP and DDRP Provides step-by-step guidance on setting up and running a successful MRP process Written by a pair of manufacturing and materials experts
Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive - and how they can be turned into potent weapons against it - is the key to managing cancer in the clinic and improving the outcome of cancer therapies. In their ground-breaking textbook, the authors provide a compelling story of how cancer works on the molecular level, and how targeted therapies using kinase inhibitors and other modulators of signaling pathways can contain and eventually cure it. The first part of the book gives an introduction into the cell and molecular biology of cancer, focusing on the key mechanisms of cancer formation. The second part of the book introduces the main signaling transduction mechanisms responsible for carcinogenesis and compares their function in healthy versus cancer cells. In contrast to the complexity of its topic, the text is easy to read. 32 specially prepared teaching videos on key concepts and pathways in cancer signaling are available online for users of the print edition and have been integrated into the text in the enhanced e-book edition.
Cancer, which has become the second-most prevalent health issue globally, is essentially a malfunction of cell signaling. Understanding how the intricate signaling networks of cells and tissues allow cancer to thrive - and how they can be turned into potent weapons against it - is the key to managing cancer in the clinic and improving the outcome of cancer therapies. In their ground-breaking textbook, the authors provide a compelling story of how cancer works on the molecular level, and how targeted therapies using kinase inhibitors and other modulators of signaling pathways can contain and eventually cure it. The first part of the book gives an introduction into the cell and molecular biology of cancer, focusing on the key mechanisms of cancer formation. The second part of the book introduces the main signaling transduction mechanisms responsible for carcinogenesis and compares their function in healthy versus cancer cells. In contrast to the complexity of its topic, the text is easy to read. 32 specially prepared teaching videos on key concepts and pathways in cancer signaling are available online for users of the print edition and have been integrated into the text in the enhanced e-book edition.
This book is biographical, practical, and theological. It covers strategies to help Christian counselors, pastors, caregivers, and friends minister to the needs of care receivers. Behaviors of dementia care receivers and others are detailed, as are strategies for caregiver stress and facing the mourning that follows.
Give the gift of light. Nothing radiates warmth and good cheer like a handmade candle--and their incredible popularity proves it. Instant Gratification: Candles demonstrates how easy it is to achieve truly elegant results by decorating purchased candles or creating beautiful candles from scratch using simple dipping and pouring techniques. With gorgeous photographs and step-by-step directions, this collection of 38 simple projects puts all of the candle-making essentials within everyone's reach.
The definitive reference for the next generation of manufacturing practitioners and leaders." -- From the Foreword by Dave Turbide, CFPIM, CMfgE, CIRM, CSCP "Finally, MRP has been brought into our new age where, in order to fight for increased share and profitability, manufacturers must not only cope with market volatility and supply chain variability, they must embrace it as a competitive weapon." -- Bob Reary, Fellow-level Certificate, APICS A fully revised and updated edition of the landmark work on material requirements planning (MRP), Orlicky's Material Requirements Planning, Third Edition focuses on the new rules required to effectively support a manufacturing operation using MRP systems in the twenty-first century. This authoritative resource offers proven solutions that help you gain the competitive edge through strategic lead time reductions, substantial reductions in total inventory investment, and significant increases in service levels. This is an indispensable tool for manufacturing practitioners and anyone preparing for CPIM certification. Coverage includes: Inventory in a manufacturing environment Principles of MRP MRP system Processing logic Lot sizing System records and files Product definition Master production schedule Inventory planning and control system System effectiveness Industry effect on MRP Project manufacturing Remanufacturing Process industry application Repetitive manufacturing application Sales and operations planning Evolution of MRP and planning systems Demand driven MRP (DDMRP) logic Strategic inventory positioning Dynamic buffers Demand driven planning Highly visible and collaborative execution DDMRP performance reporting and analytics DDMRP future Building on the pioneering work of Joseph Orlicky, this new edition of the classic text on material requirements planning (MRP) reveals the next evolutionary step for materials and supply chain synchronization in the modern manufacturing landscape. Orlicky's Material Requirements Planning, Third Edition reviews the poor business results embedded in many of today's manufacturing systems, discusses the core problems causing these results, explains an alternative pull structure for planning and controlling materials flow, and presents results from actual implementations. This thoroughly updated edition offers comprehensive coverage of MRP, describes the current state of the MRP application, and identifies the fundamental changes required to achieve sustainable success given the current global circumstances and technology options. This state-of-the art guide articulates the next generation of MRP logic--demand driven MRP (DDMRP)--and provides a roadmap for the near and distant future for this critical manufacturing management tool. Carol Ptak is currently a partner with the Demand Driven Institute, and was most recently at Pacific Lutheran University as Visiting Professor and Distinguished Executive in Residence. Previously, she was vice president and global industry executive for manufacturing and distribution industries at PeopleSoft where she developed the concept of demand driven manufacturing (DDM). Ms. Ptak spent four years at IBM Corporation culminating in the position of global SMB segment executive. Chad Smith is cofounder and managing partner of Constraints Management Group, a services and technology company specializing in pull-based manufacturing, materials, and project management systems for mid-range and large manufacturers. He has been at the forefront of developing and articulating demand driven MRP and is also an internationally recognized expert on the theory of constraints (TOC). Carol and Chad founded the Demand Driven Institute, an organization devoted to the proliferation and further development of demand driven strategies and tactics in industry.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic chemistry and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
The definitive educational resource on the clinical management of hearing disorders in children Pediatric Audiology: Diagnosis, Technology, and Management, Third Edition is fully updated with cutting edge topics reflecting the latest advances in the field. New chapters include hearing and vestibular issues in children, state-of-the-art testing methods for neonates, and longitudinal studies on cochlear implant technology. Renowned experts Jane R. Madell, Carol Flexer and rising stars Jace Wolfe and Erin C. Schafer provide meticulous discussion on all aspects of pediatric audiology—from underlying pathology and testing to medical, therapeutic, and surgical treatments. Pearls and best practices from a cadre of esteemed experts focus on achieving optimal patient outcomes. Key Features Thirty-seven chapters organized by four sections: Hearing Loss: Essential Information, Diagnosing Hearing Disorders in Infants and Children, Hearing Access Technologies for Infants and Children, and Educational and Clinical Management of Hearing Loss in Children Detailed clinical discussion of pediatric audiologic test protocols and the selection and management of technologies The neurophysiology of reading impairment — from theory to management Closed caption videos provide hands-on guidance on clinical testing techniques This richly illustrated edition is essential reading for graduate students in audiology, a robust resource for professors and audiologists who teach and mentor these students, and a go-to field guide for practicing clinicians. Paired with Pediatric Audiology Casebook, this dynamic duo is a must-have reference for trainee and veteran audiologists alike.
The classic MRP work up-to-date with new information on supply chain synchronization Thoroughly revised, Orlicky’s Material Requirements Planning, Third Edition reviews the poor business results embedded in most of today’s business systems; discusses the core problems causing the results; presents and discusses an alternative pull structure for planning and controlling materials flow; and presents initial results from actual implementations. This new edition reveals the next evolutionary step for materials and supply chain synchronization in the modern manufacturing landscape. This update describes: A solution to a chronic MRP-related problem that plagues many manufacturers: shortages of materials, components that block the smooth flow of work through the plant A competitive edge through strategic lead time reductions Significant reductions in total inventory investment Significant increases in service levels This new edition helps companies tackle three pervasive problems: unacceptable inventory performance; unacceptable service level performance; and high related expenses and waste. New to This Edition: New section on manufacturing as the heart of the supply chain management, and specific challenges in the 21st century Covers supply chain management (SCM) and distribution requirements planning (DRP) Discusses the impact of Lean and the Toyota Production System Update of integration software Reviews the emergence of demand-driven strategies and the MRP “conflict” Introduces the new concept of ASR (Actively Synchronized Replenishment) and explains how to incorporate it into business processes Explains positioning and how Six Sigma can help achieve results In-depth discussion of buffers – how to size, maintain, and adjust them New chapter on using MRP tools across the supply chain to enable pull-based approaches New case studies which illustrating the techniques described in the book Comprehensive coverage: The Whole and Its Parts; Manufacturing as a Process; Inventory Management; Prerequisites of MRP 3.0; Traditional Methodology; MRP Logic; Keeping MRP Up to Date; Lot Sizing and Safety Stock; Data Requirements and Management; MRP 3.0; Traditional MRP in Today’s Environment; MRP 3.0 Component 1—Strategic Inventory Positioning; Component 2—Buffer Level Profiling; Component 3—Dynamic Buffer Maintenance; Component 4—Pull-Based Demand Generation; Component 5—Highly Visible and Collaborative Execution; Dynamic Buffer Level Profiling; ASR Demand Generation; Applications; Developing Valid Inputs; Making Outputs Useful; Demand Driven Philosophies and MRP; Engineer to Order Environments; Lessons of the Past; Present State; The Future of MRP 3.0
A complete revision of the industry-standard book on materials requirements standards for manufacturing This fully revised and updated edition of the landmark work on material requirements planning (MRP) focuses on the new rules required to effectively support a manufacturing operation using MRP systems in the twenty-first century. You will get all-new coverage of demand-driven material requirements planning (DDMRP) along with complete implementation steps. Orlicky's Material Requirements Planning, Fourth Edition offers proven solutions that help you gain the competitive edge through strategic lead time reductions, substantial reductions in total inventory investment, and significant increases in service levels. This guide is an indispensable tool for manufacturing practitioners and anyone preparing for CPIM certification. Completely revised to follow process flow combining MRP, MRPII, ERP and DDRP Provides step-by-step guidance on setting up and running a successful MRP process Written by a pair of manufacturing and materials experts
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