Carmen Sterba made many wonderful friends during her decades in Japan, but the most impressive person she came across was someone she learned about only in books: Niijima Jo. Born Niijima Shimeta, he was given the name “Jo” by Captain William Savory on the ship Berlin. Then Captain Horace Taylor arrived on Wild Rover. He befriended the young adventurer who was determined to escape his home to learn English and find God. This will be the second full biography of Niijima Jo in English since 1891. The author chronicles Jo’s magnificent life from his fearless trip to the United States in 1864-5 to his return to Japan as a pastor to the fulfillment of his dream of establishing Doshisha University in Kyoto in 1888. Against all odds, Jo became one of Japan’s most fascinating heroes, and the way he lived his life to the fullest holds lessons for us today. Discover how an underappreciated historical figure played a critical role in the development of Japan with this fascinating biography.
This third edition of Medicinal Chemistry of Anticancer Drugs, provides an updated resource for students and researchers from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. This new edition includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theranostic anticancer agents, and pre-mRNA processing in cancer. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a unique and valuable perspective from the point of view of medicinal chemistry and drug design. It will be useful to undergraduate and postgraduate students of medicinal chemistry, pharmacology, biological chemistry, pharmacy and other health sciences. Researchers and practitioners will find a comprehensive treatment of the topic and a large number of references to reviews and the primary literature. - Provides a resource that is organized consistently based on targets and mechanisms of action from a molecular point-of-view - Focuses on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents, providing a rationalization on the action of these type of drugs and the design of new active structures - Features a large number of color figures which give information in a clear-and-concise way - Includes extensive references to review articles and primary literature - Includes updated sections on the hot topic of cancer immunotherapy, cancer polypharmacology, multitargeted cancer therapy, medicinal chemistry of cancer diagnosis, theragnostic anticancer agents, and pre-mRNA processing in cancer
Carmen Sterba made many wonderful friends during her decades in Japan, but the most impressive person she came across was someone she learned about only in books: Niijima Jo. Born Niijima Shimeta, he was given the name “Jo” by Captain William Savory on the ship Berlin. Then Captain Horace Taylor arrived on Wild Rover. He befriended the young adventurer who was determined to escape his home to learn English and find God. This will be the second full biography of Niijima Jo in English since 1891. The author chronicles Jo’s magnificent life from his fearless trip to the United States in 1864-5 to his return to Japan as a pastor to the fulfillment of his dream of establishing Doshisha University in Kyoto in 1888. Against all odds, Jo became one of Japan’s most fascinating heroes, and the way he lived his life to the fullest holds lessons for us today. Discover how an underappreciated historical figure played a critical role in the development of Japan with this fascinating biography.
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