Carlos M. Gutierrez's Books

Medicinal Chemistry of Anticancer Drugs

By: Carmen Avendaño,J. Carlos Menéndez

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Medicinal Chemistry of Anticancer Drugs

By: Carmen Avendaño,J. Carlos Menéndez

Antitumor chemotherapy is nowadays a very active field of research, and a huge amount of information on the topic is generated every year. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book addresses the need for an updated treatment from the point of view of medicinal chemistry and drug design. The focus of Medicinal Chemistry of Anticancer Drugs is on the mechanism of action of antitumor drugs from the molecular point of view and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents, aiming at the rationalization of the action of this type of drug, which would allow the design of new active structures.* Explains the biological basis of cancer treatment and the role of chemists in improving anticancer drugs* Provides the historical background and serves as a comprehensive and practical guide on cancer research and anticancer drug development* Includes coverage of different approaches to treating cancer, drug resistance, and a chapter on cancer prevention

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Page Count

459

Publisher

Elsevier

Published Date

ISBN 10

008055962X

ISBN 13

9780080559629

Ecological Indicators for Coastal and Estuarine Environmental Assessment

A User Guide

By: João Carlos Marques

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Ecological Indicators for Coastal and Estuarine Environmental Assessment

A User Guide

By: João Carlos Marques

Ecological indicators address ecosystems structure and/or function and are commonly used to provide synoptic information about their state. Through quantitative representations of either the forces that steer ecosystems, responses to forcing functions, or of previous, current, or future states of an ecosystem, indicators are expected to reveal conditions and trends that will help in development planning and decision making processes. Ecological indicators combine numerous environmental factors in a single value, which may be useful in terms of management and in the development of ecological concepts, compliant with the general public's understanding. Nevertheless, their application is not exempt of criticisms, the first of which is that aggregation results in an oversimplification of the ecosystem under observation. Ecological indicators must therefore be handled following the right criteria and in situations that are consistent with its intended use and scope; otherwise they may drive to confusing interpretations of data.

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Page Count

210

Publisher

WIT Press

Published Date

ISBN 10

1845642090

ISBN 13

9781845642099

Pio Pico

The Last Governor of Mexican California

By: Carlos Manuel Salomon

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Pio Pico

The Last Governor of Mexican California

By: Carlos Manuel Salomon

Two-time governor of Alta, California and prominent businessman after the U.S. annexation, Pío de Jesus Pico was a politically savvy Californio who thrived in both the Mexican and the American periods. This is the first biography of Pico, whose life vibrantly illustrates the opportunities and risks faced by Mexican Americans in those transitional years. Carlos Manuel Salomon breathes life into the story of Pico, who—despite his mestizo-black heritage—became one of the wealthiest men in California thanks to real estate holdings and who was the last major Californio political figure with economic clout. Salomon traces Pico’s complicated political rise during the Mexican era, leading a revolt against the governor in 1831 that swept him into that office. During his second governorship in 1845 Pico fought in vain to save California from the invading forces of the United States. Pico faced complex legal and financial problems under the American regime. Salomon argues that it was Pico’s legal struggles with political rivals and land-hungry swindlers that ultimately resulted in the loss of Pico’s entire fortune. Yet as the most litigious Californio of his time, he consistently demonstrated his refusal to become a victim. Pico is an important transitional figure whose name still resonates in many Southern California locales. His story offers a new view of California history that anticipates a new perspective on the multicultural fabric of the state.

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Page Count

291

Publisher

University of Oklahoma Press

Published Date

ISBN 10

0806183489

ISBN 13

9780806183480

Building a Nation

The Case of Echeverria

By: Juan Carlos Mercado

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Building a Nation

The Case of Echeverria

By: Juan Carlos Mercado

This book is the only one of its kind on the market. It deals with one of the most brilliant yet least known Latin American authors, Esteban EcheverrÌa. EcheverrÌa was the author of La Cautiva (The Captive), El Matadero (The Slaughterhouse), and Dogma Socialista (Socialist Dogma) which formed the base of the constitution of the Republic of Argentina. In Building A Nation, Juan Carlos Mercado recovers the figure of EcheverrÌa through an analysis centralized in his work as a poet, thinker, and politician--all as one unit. The study takes into account the many sources, including European ones, that EcheverrÌa used in order to formulate a literary and political national project. Readers of this work will acquire a thorough understanding of the significance of EcheverrÌa's influence--from the introduction of European Romanticism into Argentine Literature; to the initiation of a critical and realistic narrative style never yet seen before in Argentina; to the founding of a liberal-humanist tendency which went on to acquire definitive political shape for the country.

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Page Count

256

Publisher

University Press of America

Published Date

ISBN 10

0761801146

ISBN 13

9780761801146

Statistical Abstract of the United States

The National Data Book

By: Carlos M. Gutierrez,Cynthia A. Glassman,Charles Louis Kincannon

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Statistical Abstract of the United States

The National Data Book

By: Carlos M. Gutierrez,Cynthia A. Glassman,Charles Louis Kincannon

The 127th edition of the Statistical Abstract of the United States continues a proud tradition of presenting a comprehensive and useful portrait of the social, political, and economic organization of the United States. The 2008 edition provides: More than 1,300 tables and graphs on topics such as births and deaths, education, government finances, homeland security, income, poverty, and information technology. Expanded guide to other sources of statistical information both in print and on the Web. Listing of metropolitan and micropolitan areas and their population numbers. Book jacket.

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Page Count

1016

Publisher

Bureau of Census

Published Date

ISBN 10

0160795842

ISBN 13

9780160795848

Book's by Carlos M. Gutierrez

Medicinal Chemistry of Anticancer Drugs

Medicinal Chemistry of Anticancer Drugs

Ecological Indicators for Coastal and Estuarine Environmental Assessment

Ecological Indicators for Coastal and Estuarine Environmental Assessment

Pio Pico

Pio Pico

Building a Nation

Building a Nation

Statistical Abstract of the United States

Statistical Abstract of the United States

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