This report is the outcome of a consensus-building project to agree on best practices for environmental and nutritional Life Cycle Assessment (nLCA) methodology, and identify future research needs. The project involved 30 nutritional and environmental LCA researchers from 18 countries. It focused on the assessment of food items (as opposed to meals or diets). Best practice recommendations were developed to address the intended purpose of an LCA study and related modeling approach, choice of an appropriate functional unit, assessment of nutritional value, and reporting nLCA results. An nLCA study should report the quantities of as many essential nutrients as possible and aim to provide information on the nutritional quality and/or health impacts in addition to nutrient quantities. Outstanding issues requiring further research attention include: defining a minimum number of nutrients to be considered in an nLCA study; treatment of nutrients to limit; use of nutrient indexes; further development of Impact Assessment methods; representation of nutritional changes that may occur during subsequent distribution and food preparation in cradle-to-gate nLCA studies; and communication of data uncertainty and variability. More data are required for different regions (particularly developing countries); for the processing, distribution, retail, and consumption life cycle stages; and for food loss and waste. Finally, there is a need to extend nLCA methodology for the assessment of meals and diets, to consider further how to account for the multi-functionality of food in a sustainability framework, and to set nLCA studies within the context of environmental limits. These results provide a robust basis for improving nLCA methodology and applying it to identify solutions that minimize the trade-offs between nourishing populations and safeguarding the environment.
Biotechnology represents a major area of research focus, and many universities are developing academic programs in the field. This guide to biomanufacturing contains carefully selected articles from Wiley's Encyclopedia of Industrial Biotechnology, Bioprocess, Bioseparation, and Cell Technology as well as new articles (80 in all,) and features the same breadth and quality of coverage and clarity of presentation found in the original. For instructors, advanced students, and those involved in regulatory compliance, this two-volume desk reference offers an accessible and comprehensive resource.
Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed, almost doubling the amount of chemical information with an additional volume. As in the predecessor, a short introductory section covers the theoretical background and evaluates currently available instrumentation and equipment. The main part of the book then goes on to systematically survey the complete range of published microwave-assisted synthesis methods from their beginnings in the 1990s to mid-2011, drawing on data from more than 5,000 reports and publications. Throughout, the focus is on those reactions, reagents and reaction conditions that work, and that are the most relevant for medicinal and natural products chemistry. A much expanded section is devoted to combinatorial, highthroughput and flow chemistry methods.
Rabies is the most current and comprehensive account of one of the oldest diseases known that remains a significant public health threat despite the efforts of many who have endeavored to control it in wildlife and domestic animals. During the past five years since publication of the first edition there have been new developments in many areas on the rabies landscape. This edition takes on a more global perspective with many new authors offering fresh outlooks on each topic. Clinical features of rabies in humans and animals are discussed as well as basic science aspects, molecular biology, pathology, and pathogenesis of this disease. Current methods used in defining geographic origins and animal species infected in wildlife are presented, along with diagnostic methods for identifying the strain of virus based on its genomic sequence and antigenic structure. This multidisciplinary account is essential for clinicians as well as public health advisors, epidemiologists, wildlife biologists, and research scientists wanting to know more about the virus and the disease it causes. - Offers a unique global perspective on rabies where dog rabies is responsible for killing more people than yellow - More than 7 million people are potentially exposed to the virus annually and about 50,000 people, half of them children, die of rabies each year - New edition includes greatly expanded coverage of bat rabies which is now the most prominent source of human rabies in the New World and Western Europe, where dog rabies has been controlled - Recent successes of controlling wildlife rabies with an emphasis on prevention is discussed - Approximately 40% updated material incorporates recent knowledge on new approaches to therapy of human rabies as well as issues involving organ and tissue transplantation - Includes an increase in illustrations to more accurately represent this diseases' unique horror
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