Chemical Induction of Cancer: Structural Bases and Biological Mechanisms, Volume IIIC: Natural, Metal, Fiber, and Macromolecular Carcinogens covers structure-carcinogenicity relationships of carcinogenic mycotoxins, carcinogenic substances generated by plants, carcinogenic metals and metalloids, and foreign-body carcinogens. The book discusses the metabolism and mechanism of carcinogenic action, physicochemical properties, other biological activities (principally mutagenicity and teratogenicity), modification of carcinogenic activity, formation and environmental significance. The text also describes the carcinogenic water-soluble high polymers and explores the intriguing problems of the carcinogenic effect of osmotic imbalance in tissue microenvironment, as well as of spontaneous malignant transformation occurring in cell cultures in vitro. Studies on tumor induction and carcinogenesis modification by nonviral nucleic acids, by nucleases, proteases, histones, and by antigenic stimulation as well as by antibodies are also considered. The book further tackles tumor-released factors as possible modifiers of carcinogenesis. The text will prove invaluable to chemists and people involved in cancer research.
Chemical Induction of Cancer: Structural Bases and Biological Mechanisms Volume IIIA deals with the organic and biochemical principles behind cancer. This volume contains the continuation of Volume IIA, which tackles structure-activity relationships of chemical carcinogens, the effect of chemical reactivity, molecular geometry, and metabolism on carcinogenic activity. Under this is non-conjugated organic compounds. The text is recommended for doctors, organic chemists, and biochemists with an advanced knowledge in biochemistry and organic chemistry and would like to know more the biochemical processes of cancer.
This book provides a cross-cultural analysis of how religious symbols function from a theological and philosophical perspective. Showing how religious symbols can be true in various qualified senses, Neville presents a theory of religious symbolism in the American pragmatic tradition extending and elaborating Tillich's claim that religious symbols participate in the divine realities to which they refer and yet must be broken in order not to be idolatrous or demonic. The Truth of Broken Symbols offers a theory of religious symbolism treating reference, meaning, and interpretation, and discussing different functions of religious symbols in theological, practical, and devotional contexts. It shows that religious symbols are to be properly understood as true or false and that symbol-systems such as myths, theologies, or liturgical symbols are to be used to engage divine realities while internally exhibiting semiotic structures of reference, meaning, and interpretation.
Given the unprecedented demands on the U.S. military since 2001 and the risks posed by stress and trauma, there has been growing concern about the prevalence and consequences of sleep problems. This first-ever comprehensive review of military sleep-related policies and programs, evidence-based interventions, and barriers to achieving healthy sleep offers a detailed set of actionable recommendations for improving sleep across the force.
This paper summarizes the current state of concepts and approaches for addressing deforestation in the trade, marketing, and production of agricultural commodities that have a disproportionate impact on forests at international, national, and landscape level. To date, predominant attention has been directed towards the role of the private sector and "consumer countries" that shape market regulation. This publication aims to complement the international discourse by generating a greater focus on the role of "producer country" governments at the national and local level to support efforts to decouple agricultural production from deforestation.
This text fuses scientific integrity with conversational, humorous presentation of neuroscience knowledge for human services. Knowledge conveyed is essential for practice with mental health, addiction, and developmental challenges, violence, family relationships
There is a growing realization that business development is the most effective weapon in fighting world poverty. How the for-profit model can be harnessed to provide the poor with a share in the world's prosperity is discussed through actual cases, and nested in innovative theories of business, social sciences, and philosophy.
Comprehensive, systematic, and balanced, Systems of Psychotherapy uses a wealth of clinical cases to help readers understand a wide variety of psychotherapies - including psychodynamic, existential, experiential, interpersonal, exposure, behavioral, cognitive, third wave, systemic, multicultural, and integrative. The ninth edition of this landmark text thoroughly analyzes 15 leading systems of psychotherapy and briefly surveys another 32, providing students and practitioners with a broad overview of the discipline. The book explores each system's theory of personality, theory of psychopathology, and resulting therapeutic process and therapy relationship. Through these explorations the authors clearly demonstrate how psychotherapy systems agree on the processes producing change while diverging on the elements in need of change. Additionally, the authors present cogent criticisms of each approach from cognitive-behavioral, psychoanalytic, humanistic, cultural, and integrative perspectives. This ninth edition features updated meta-analytic reviews of the effectiveness of each system, new sections on Lacanian analysis, mentalization therapy, and psychotherapy with gender nonconforming people, as well as new sections and updates throughout the text.
Build a solid foundation of knowledge based on the fundamentals and employ step-by-step instruction from Spine Surgery. Edited by Edward C. Benzel, this best-selling medical reference explores the full spectrum of surgical techniques used in spine surgery and delivers the comprehensive, cutting-edge guidance you need to achieve successful outcomes. Online access, thorough updates, contributions by leading international authorities, an abundance of detailed illustrations, and procedural video clips provide everything you need to avoid and manage complex problems. Glean essential, up-to-date, need-to-know information in one comprehensive reference that explores the full spectrum of surgical techniques used in spine surgery. Hone your surgical skills and technique with intraoperative videos and more than 800 outstanding illustrations demonstrating each technique step by step. Grasp and apply the latest knowledge from more than 25 brand-new chapters, as well as extensive revisions or total rewrites to the majority of existing chapters to present all of the most up-to-date information available on every aspect of spine surgery including motion preservation technologies, endovascular management, back pain and psychosocial interactions, biomechanics, and more. Consult with the best. Renowned neurosurgery authority Edward C. Benzel leads an international team of accomplished neurosurgeons and orthopedic surgeons - many new to this edition - who provide dependable guidance and share innovative approaches to surgical techniques and complications management. Equip yourself to address increasing occurrences of pain among aging and physically active patients. Access the information you need, where you need it on your laptop or mobile device via expertconsult.com, with fully searchable text, a wealth of procedural videos, online updates from the experts, downloadable image gallery and links to PubMed.
Solve potential behavior problems before they arise with this practical guide Veterinary Guide to Preventing Behavior Problems in Dogs and Cats offers a practical, easy-to-read manual on effective interventions to avoid behavior problems. Written to support veterinarians and staff, this guide supplies concrete recommendations to use in veterinary clinics and the home environment. The book emphasizes learning theory, animal body language, and normal puppy and kitten development, and discusses shelter animals and their unique needs. The book includes chapters on the veterinary clinic environment and ways to reduce fear, anxiety, and stress associated with medical care. It also covers how to recognize problem behaviors, pet selection, and important information about kids and pets. Veterinary Guide to Preventing Behavior Problems in Dogs and Cats provides: Knowledge and tools for client education, environmental management, and prevention Detailed discussion of topics including body language, basic learning theory, and specific strategies for particular animals Advice on how to reduce fear, anxiety, and stress in the veterinary clinic Veterinary Guide to Preventing Behavior Problems in Dogs and Cats is an ideal reference for veterinarians, veterinary technicians, veterinary staff and trainers, and veterinary students.
Describes a selection of important parallel algorithms for matrix computations. Reviews the current status and provides an overall perspective of parallel algorithms for solving problems arising in the major areas of numerical linear algebra, including (1) direct solution of dense, structured, or sparse linear systems, (2) dense or structured least squares computations, (3) dense or structured eigenvaluen and singular value computations, and (4) rapid elliptic solvers. The book emphasizes computational primitives whose efficient execution on parallel and vector computers is essential to obtain high performance algorithms. Consists of two comprehensive survey papers on important parallel algorithms for solving problems arising in the major areas of numerical linear algebra--direct solution of linear systems, least squares computations, eigenvalue and singular value computations, and rapid elliptic solvers, plus an extensive up-to-date bibliography (2,000 items) on related research.
For over fifty years, Bill C. Malone has researched and written about the history of country music. Today he is celebrated as the foremost authority on this distinctly American genre. This new collection brings together his significant article-length work from a variety of sources, including essays, book chapters, and record liner notes. Sing Me Back Home distills a lifetime of thinking about country and southern roots music. Malone offers the heartfelt story of his own working-class upbringing in rural East Texas, recounting how in 1939 his family’s first radio, a battery-powered Philco, introduced him to hillbilly music and how, years later, he went on to become a scholar in the field before the field formally existed. Drawing on a hundred years of southern roots music history, Malone assesses the contributions of artists such as William S. Hays, Albert Brumley, Joe Thompson, Jimmie Rodgers, Johnny Gimble, and Elvis Presley. He also explores the intricate relationships between black and white music styles, gospel and secular traditions, and pop, folk, and country music. Author of many books, Malone is best known for his pioneering volume County Music, U.S.A., published in 1968. It ranks as the first comprehensive history of American country music and remains a standard reference. This compilation of Malone’s shorter—and more personal—essays is the perfect complement to his earlier writing and a compelling introduction to the life’s work of America’s most respected country music historian.
Post-war, post-industrialism, post-religion, post-truth, post-biological, post-human, post-modern. What succeeds the post- age? Mark C. Taylor returns here to some of his central philosophical preoccupations and asks: What comes after the end? Abiding Grace navigates the competing Hegelian and Kierkegaardian trajectories born out of the Reformation and finds Taylor arguing from spaces in between, showing how both narratives have shaped recent philosophy and culture. For Hegel, Luther’s internalization of faith anticipated the modern principle of autonomy, which reached its fullest expression in speculative philosophy. The closure of the Hegelian system still endures in the twenty-first century in consumer society, financial capitalism, and virtual culture. For Kierkegaard, by contrast, Luther’s God remains radically transcendent, while finite human beings and their world remain fully dependent. From this insight, Heidegger and Derrida developed an alternative view of time in which a radically open future breaks into the present to transform the past, demonstrating that, far from autonomous, life is a gift from an Other that can never be known. Offering an alternative genealogy of deconstruction that traces its pedigree back to readings of Paul by way of Luther, Abiding Grace presents a thoroughgoing critique of modernity and postmodernity’s will to power and mastery. In this new philosophical and theological vision, history is not over and the future remains endlessly open.
The concept of authoritarianism, first defined in The Authoritarian Personality published in 1950, has since been treated in a bewildering array of studies that have explored both its narrow psychological meaning and its broader social implications. In this volume, authors John P. Kirscht and Ronald C. Dillehay have provided a much-needed review of this growing subject, summarizing and evaluating about 260 studies that have appeared to date. Kirscht and Dillehay differentiate between the psychological and the sociological approach to authoritarianism, tracing the historical development of both schools of thought. They also outline three major views of authoritarianism: as antecedent to certain types of behavior (for example, ethnic prejudice), as the consequence of other variables (such as child rearing practices), or as a correlate of yet other processes(e.g. alienation); these views, in turn, suggest a variety of theoretical and methodological issues. The authors review, in addition, the multitudes of beliefs and behaviors thought to vary with authoritarianism, examining the validity of these relationships in empirical research. While the authors do not attempt to reformulate or redefine authoritarianism, they point up avenues for future research and single out significant research findings which are likely to offer the firmest ground for development.
This detailed study of the excavation and restoration of the city of Nauvoo, Illinois, reveals the roots of historical archaeology. In the late 1960s, the Church of Jesus Christ of Latter-day Saints sponsored an archaeology program to authentically restore the city of Nauvoo, which was founded along the Mississippi River in the 1840s by the Mormons as they moved west. Non-Mormon scholars were also interested in Nauvoo because it was representative of several western frontier towns in this era. As the archaeology and restoration of Nauvoo progressed, however, conflicts arose, particularly regarding control of the site and its interpretation for the public. The field of historical archaeology was just coming into its own during this period, with myriad perspectives and doctrines being developed and tested. The Nauvoo site was one of the places where the discipline was forged. This well-researched account weaves together multiple viewpoints in examining the many contentious issues surrounding the archaeology and restoration of the city of Nauvoo, Illinois, providing an illuminating picture of the early days of professional historical archaeology.
Summarizes information on all aspects of metallic zinc and gives references to additional source material, including major books and reviews. At the heart of the reference are 16 chapters that cover coatings and electrochemical protection of steel by zinc. Other chapters address: occurrence and prod
This book examines the link between change and project management and how creating a closer alignment between these two methodologies can yield greater benefits and mitigate elements of failure of information systems (IS) projects. This study explores the underlying challenges and practicalities of closer integration of the two disciplines and asserts that such a successful change goes beyond the simple training of project managers in the practitioner context. Instead, it requires organizations to conceptualize the necessary challenges to realize the potential benefits of this recommended integrated approach. The integration of both project and change management has been advocated in existing research, but the challenges of moving from a current position of separate methodologies, different standards bodies and in some cases totally separate organizational structures, is a step change for many organizations. Change initiatives where good change management practices are implemented, can increase the probability of successful organizational change. The tasks of leading and sustaining change can be complex and often entail the interplay of multiple factors involving action by people at every level of the business. This book offers a guide that identifies the barriers and major challenges that may arise in the development of the closer integration of change and project management. With a better understanding of these issues, organizations can avoid such pitfalls when establishing their own integrated approach.
Obtain all the core knowledge in pain management you need from one of the most trusted resources in the field. The new edition of Practical Management of Pain gives you completely updated, multidisciplinary overview of every aspect of pain medicine, including evaluation, diagnosis of pain syndromes, rationales for management, treatment modalities, and much more. In print and online, it is all the expert guidance necessary to offer your patients the best possible relief. "In summary, this is the best explanation of what lies behind MRI that I have read, taking what can be a dry subject and making it readily understandable and really interesting. I would recommend it to anyone starting their MRI training and anyone trying to teach MRI to others." Reviewed by RAD Magazine, June 2015 Understand and apply the latest developments in pain medicine with brand-new chapters covering disability assessment, central post-stroke pain, chronic widespread pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics). Access up-to-the-minute knowledge on all aspects of pain management, from general principles to specific management techniques, with contributions from renowned experts in the field. Read the full text and view all the images online at expertconsult.com. Understand and apply the latest developments in pain management with brand-new chapters covering disability assessment, central post-stroke pain, widespread chronic pain, and burn pain. Effectively ease your patients' pain with today's best management techniques, including joint injections, ultrasound-guided therapies, and new pharmacologic agents (such as topical analgesics).
This therapist guide provides instruction for delivering treatment to individuals with MS who are experiencing stress and depressed mood. The stress and mood management program described has been developed over more than ten years of research and clinical trials. The treatment is based on cognitive-behavioral therapy (CBT) and is divided into two parts. Part I incorporates standard behavioral activation and cognitive restructuring techniques while Part II consists of optional modules designed to address specific problems that are common among MS patients.
A collection of oral histories that reveal the loss of cultural continuity, identity, shifts in family responsibilities, gender roles and fractured relationships between generations that are just some of the challenges people face as they attempt to rebuild lives and communities.
Bayesian Reliability presents modern methods and techniques for analyzing reliability data from a Bayesian perspective. The adoption and application of Bayesian methods in virtually all branches of science and engineering have significantly increased over the past few decades. This increase is largely due to advances in simulation-based computational tools for implementing Bayesian methods. The authors extensively use such tools throughout this book, focusing on assessing the reliability of components and systems with particular attention to hierarchical models and models incorporating explanatory variables. Such models include failure time regression models, accelerated testing models, and degradation models. The authors pay special attention to Bayesian goodness-of-fit testing, model validation, reliability test design, and assurance test planning. Throughout the book, the authors use Markov chain Monte Carlo (MCMC) algorithms for implementing Bayesian analyses -- algorithms that make the Bayesian approach to reliability computationally feasible and conceptually straightforward. This book is primarily a reference collection of modern Bayesian methods in reliability for use by reliability practitioners. There are more than 70 illustrative examples, most of which utilize real-world data. This book can also be used as a textbook for a course in reliability and contains more than 160 exercises. Noteworthy highlights of the book include Bayesian approaches for the following: Goodness-of-fit and model selection methods Hierarchical models for reliability estimation Fault tree analysis methodology that supports data acquisition at all levels in the tree Bayesian networks in reliability analysis Analysis of failure count and failure time data collected from repairable systems, and the assessment of various related performance criteria Analysis of nondestructive and destructive degradation data Optimal design of reliability experiments Hierarchical reliability assurance testing
Affecting Grace examines the importance of Shakespeare’s poetry and plays within German literature and thought after 1750 – including its relationship to German classicism, which favoured unreflected ease over theatricality. Kenneth S. Calhoon examines this tension against an extensive backdrop that includes a number of canonical German authors – Goethe, Schiller, Herder, Lessing, von Kleist, and Nietzsche – as well as the advent of Meissen porcelain, the painting of Bernardo Bellotto and Francesco Guardi, and aspects of German styles of architecture. Extending from Shakespeare’s The Merchant of Venice (c. 1597) to Kleist’s The Broken Jug (1806), this study turns on the paradox that the German literary world had begun to embrace Shakespeare just as it was firming up the broad but pronounced anti-Baroque sensibility found pivotally in Lessing’s critical and dramatic works. Through these investigations, Calhoon illuminates the deep cultural changes that fundamentally affected Germany’s literary and artistic traditions.
Taylor (humanities and religion, Williams College, Massachusetts) reconsiders the two philosophers based on the notion that all modern philosophy lies between the poles of their thought. He has added a new introduction to the 1980 original edition.
This book explores the rapidly growing interdisciplinary area of hermeneutics and its significance for biblical studies, combining wide, fundamental, rigorous, and creative theoretical concerns with practical questions about how we read biblical texts.
A provocative report on the state of American higher education discusses the consequences of decades of neglect and covers such recommendations as discontinuing tenure, refocusing on education over research, and tapping new technologies.
Much about the Korean War still is hidden and much will long remain hidden. Nevertheless, an attempt was made by the author to give a historical account of the 7th Cavalry Regiment's activities during Occupation Duty in Japan after World War II and combat actions within the Korean War. This was accomplished by exploring all known official existing records in the National Military Archives, which have been quoted freely and very often verbatim to give a truthful view of events as they existed at that particular time. Throughout the years, the original records of the 7th Cavalry Regiment have suffered from many disasters. On March 30, 1952, a fire destroyed the regimental headquarters in Japan, and everything was burned except the regimental colors. To further complicate the matter, but to comply with orders, many valuable records were destroyed to accomplish what they thought was "cleaning out useless files." What this actually caused or created was the existence of incomplete and often inaccurate records. Perhaps this book will have an eye-opening effect for the reader and will stir memories and answer questions that still prevail or persist. For those who were there, survived the many struggles and hardships, and turned the tide of defeat to victory, I salute all of you. I apologize and ask forgiveness for any errors or omissions that annoy all of those who dare to analyze the confusion, the chaos of battle, to a smartly phrased story. —from the Preface
The Fourth Edition of Environmental Communication and the Public Sphere remains the only comprehensive introduction to the growing field of environmental communication, ranging from an historical overview of key terms to important legal and technological developments. This innovative book focuses on how human communication influences the way we perceive and act in the environment. It also examines how we interpret environmental “problems” and decide what actions to take with regard to the natural world. Three-time president of the Sierra Club, the largest environmental group in the United States, lead author Robert Cox leverages his vast experience to offer insights into the news media, Congress, environmental conflict, advocacy campaigns, and other real-world applications of environmental communication. New coauthor Phaedra Pezzullo brings two decades of applied experience working with grassroots environmental justice and health organizations, citizen advisory boards, and student-led campaigns, as well as her internationally recognized research on toxic pollution, social injustices, public advocacy, and more. The authors introduce the reader to the major areas, terms, and debates of this evolving field. The Fourth Edition incorporates major revisions that include four new chapters on visual and popular culture, digital media and activism, the sustainability of college and corporation campuses, and the legal “standing” of citizens and nature. Updates throughout the text draw on timely topics including visual communication used in climate science campaigns, fracking and challenges to the right to know, plastic bag bans, consumer apps, digital activism for environmental justice, green marketing, and arguments on giving legal rights to nonhuman entities from dolphins to rivers.
Mark C. Taylor provocatively claims that contemporary art has lost its way. With the art market now mirroring the art of finance, many artists create works solely for the purpose of luring investors and inspiring trade among hedge funds and private equity firms. When art is commodified, corporatized, and financialized, it loses its critical edge and is transformed into a financial instrument calculated to maximize profitable returns. Joseph Beuys, Matthew Barney, James Turrell, and Andy Goldsworthy are artists who differ in style, yet they all defy the trends that have diminished art's potential in recent decades. They understand that art is a transformative practice drawing inspiration directly and indirectly from ancient and modern, Eastern and Western forms of spirituality. For Beuys, anthroposophy, alchemy, and shamanism drive his multimedia presentations; for Barney and Goldsworthy, Celtic mythology informs their art; and for Turrell, Quakerism and Hopi myth and ritual shape his vision. Eluding traditional genres and classifications, these artists combine spiritually inspired styles and techniques with material reality, creating works that resist merging space into cyberspace in a way that overwhelms local contexts with global networks. Their art reminds us of life's irreducible materiality and humanity's inescapability of place. For them, art is more than just an object or process—it is a vehicle transforming human awareness through actions echoing religious ritual. By lingering over the extraordinary work of Beuys, Barney, Turrell, and Goldsworthy, Taylor not only creates a novel and personal encounter with their art but also opens a new understanding of overlooked spiritual dimensions in our era.
Neville's most significant scholarly contribution is arguably his metaphysical theory of being (or being-itself): a new theory that involves an original solution to the ancient problem of the one and the many. He developed this theory for his PhD dissertation at Yale University (graduated 1963), of which his first book, God the Creator, constitutes a substantial revision. Exploring the implications of that theory has enabled him to produce a philosophy of nature that rivals Alfred North Whitehead's in scope and power, as can be seen from his three-volume Axiology of Thinking. The first volume in that trilogy, Reconstruction of Thinking (1981), was hailed by Donald W. Sherburne?editor of the corrected edition of Whitehead's Process and Reality?as "a truly important book. It is the first genuinely neo-Whiteheadian offering on a large, systematic scale."The second volume of the trilogy, Recovery of the Measure: Interpretation and Nature (1989), was also well received. The prominent Confucian scholar and philosopher David L. Hall wrote of it as follows: "Because of its timeliness, the brilliance of its arguments, and the profundity of its conclusions,
A powerful consideration of the lessons imparted in the final works of essential writers and philosophers For many today, retirement and the leisure said to accompany it have become vestiges of a slower, long-lost time. In a world where the sense of identity is tied to work and careers, to stop working often is to become nobody. In this deeply perceptive and personal exploration of last works, Mark C. Taylor poignantly explores the final reflections of writers and thinkers from Kierkegaard to David Foster Wallace. How did they either face or avoid ending and leaving? What do their lessons in ending teach us about living in the time that remains for us? Some leavings brought relief, even joy, while others brought pain and suffering. Whether the cause was infirmity, impending death, or simply exhaustion and ennui, the ways these influential voices fell silent offer poignant examples of people withdrawing from the world’s stage. Throughout this learned and moving book, Taylor probes how the art of living involves learning to leave gracefully.
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