Combining earth science, subsurface hydrology and environmental geochemistry, this book provides a comprehensive background for those interested in the protection and sustainable management of the subsurface environment. The reader is introduced to the chemistry of contaminants, which usually disturb the natural equilibrium in the subsurface as a result of human activity. One focus of the book is on contaminant reactions in soil solutions. Discussions on case studies are provided.
Since the publication of the first edition of The Diabetic Pancreas in 1977, much progress has been made in various areas of diabetes research. While only a rela tively short while ago diabetes was considered a single disease, in more recent years it has become apparent that it is a heterogeneous group of disorders, all of which are characterized by a decreased tolerance of carbohydrates and most of which have a genetic basis, although the genetic types vary. In more recent years, an International Work Group sponsored by the National Diabetes Data Group of the NIH proposed a now generally accepted classification, according to which the insulin-dependent ketosis-prone diabetes, formerly and inappropriately called the juvenile type, is considered a subclass of diabetes, type 1. Because it can occur at any age, it was recommended that the diagnosis based on age be eliminated. The non-insulin-dependent, non-keto sis-prone type of diabetes, which is not secondary to other diseases or conditions, and which was formerly called matu rity-onset diabetes, was considered a second subclass, type II, because although this form usually develops after age 40, it also occurs in young persons, who do not require insulin or are not ketotic. Although this classification is not entirely agreed upon by all diabetologists, for practical purposes it has been generally accepted and has been utilized by the contributors to this volume.
The Construction Manuals from Edition Detail are among the most important reference works in the specialist literature. The latest volume shows the potential of the material concrete and documents comprehensively the technical principles of using concrete in construction. Chapters cover the history of the material, the properties of concrete, reinforced concrete, and prestressed concrete, the treatment of its surface. Also covered are the basic principles of statics for large and small structures, and the building requirements with respect to heat, damp, sound-proofing and fire protection according to the most recent norms and standards. Finally a large number of built examples are presented from illustrations of the complete structure down to detailed plans, showing the broad spectrum of applications for concrete in contemporary building. All plans have been specially produced by the editorial department Detail for this book and for ease of comparison, they have been drawn to the same scale.
Physical Acoustics in the Solid State reviews the modern aspects in the field, including many experimental results, especially those involving ultrasonics. It covers practically all fields of solid-state physics. After a review of the relevant experimental techniques and an introduction to the theory of elasticity, the book details applications in the various fields of condensed matter physics.
The way that we interact with the environment on a daily basis is inherently multisensory. Even a simple task such as judging the location of a light in a dark room depends not only on vision but also on proprioceptive cues about the position of our body in space. The way that we experience food can be influenced not just by taste and smell, but by visual and auditory cues. Perception: A multisensory perspective adopts a multisensory approach to understanding perception. Rather than discussing each sense separately, this book defines perception as intrinsically multisensory from the start and examines multisensory interactions as the key process behind how we perceive our own body, control its movements, and perceive and recognise objects, space, and time. But the book delves even deeper. It discusses multisensory processing in conditions such as synaesthesia. It addresses attention and the role of multisensory processing in learning. By focussing on these domains, the authors highlight and identify general principles in the field of perception study and introduce models, experimental methods and pathologies that will be of interest to all those studying within the field of perception. The authors also illustrate applications that will be of interest to professionals whose work takes multisensory processing into account. As an introduction to the topic of multisensory perception, Perception: A multisensory perspective will be essential reading for students, from advanced undergraduate level through to postgraduate level in psychology, philosophy, and neuroscience. Those studying physiotherapy and neurological rehabilitation, human-computer interface development, or the design of products or services will also find this book of interest.
What kind of allusion is possible in a poetry derived from a centuries-long oral tradition, and what kind of oral-derived poetry are the Homeric epics? Comparison of Homeric epic with South Slavic heroic song has suggested certain types of answers to these questions, yet the South Slavic paradigm is neither straightforward in itself nor necessarily the only pertinent paradigm: Augustan Latin poetry uses many sophisticated and highly self-conscious techniques of allusion which can, this book contends, be suggestively paralleled in Homeric epic, and some of the same techniques of allusion can be found in Near Eastern poetry of the third and second millennia BC. By attending to these various paradigms, this challenging study argues for a new understanding of Homeric allusion and its place in literary history, broaching the question of whether there can have been historical continuity in a poetics of allusion stretching from the Mesopotamian epic of Gilgamesh, via the Iliad and Odyssey, to the Aeneid and Metamorphoses, despite the enormous disparities of time and place and of language and culture, including those represented by the cuneiform tablet, the papyrus roll, and by an oral performance culture. The fundamental methodological problems are explored through a series of interlocking case studies, treating of how the Odyssey conceivably alludes to the Iliad and also to earlier poetry on Odysseus' homecoming, the Iliad to earlier poetry on the Ethiopian hero Memnon, the Homeric Hymn to Demeter to earlier poetry on Hades' abduction of Persephone, and early Greek epic to Mesopotamian mythological poetry, pre-eminently the Babylonian epic of Gilgamesh.
Multilevel Structural Equation Modeling by Bruno Castanho Silva, Constantin Manuel Bosancianu, and Levente Littvay serves as a minimally technical overview of multilevel structural equation modeling (MSEM) for applied researchers and advanced graduate students in the social sciences. As the first book of its kind, this title is an accessible, hands-on introduction for beginners of the topic. The authors predict a growth in this area, fueled by both data availability and also the availability of new and improved software to run these models. The applied approach, combined with a graphical presentation style and minimal reliance on complex matrix algebra guarantee that this volume will be useful to social science graduate students wanting to utilize such models.
Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models, Second Edition, summarizes the most important developments in in vitro models for predicting the permeability of drugs. This book is structured around three different approaches, summarizing the most recent achievements regarding models comprising (i) immortalized cells with an intrinsic ability to grow as monolayers when seeded in permeable supports, (ii) primary cells isolated from living organisms and directly cultured as barrier monolayers, and (iii) tissue-based models constructed with cell lines and extracellular matrix that resembles the tridimensional structure of mucosae and other biological membranes, or animal/patient-derived tissues. Each model is covered in detail, including the protocol of generation and application for specific drugs/drug delivery systems. The equivalence between in vitro cell and tissue models and in vivo conditions is discussed, highlighting how each model may provisionally resemble different drug absorption route. Chapters included in the first edition were updated with relevant data published in recent years, while four new chapters were included to reflect new emerging directions and trends in drug permeability models. Concepts and Models for Drug Permeability Studies: Cell and Tissue Based in Vitro Culture Models, Second Edition, is a critical reference for drug discovery and drug formulation scientists interested in delivery systems intended for the administration of drugs through mucosal routes and other important tissue barriers (e.g. the BBB). Researchers studying mucosal biology can use this book to familiarize themselves and exploit the synergic effect of mucosal delivery systems and biomolecules. - Summarizes the current advances in the use of permeability models in drug transport - Covers the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, renal, skin, and blood–brain barrier in vitro models. Includes case studies to facilitate understanding of various concepts in computer-aided applications - Updates in the second edition include organ-on-chip devices, 3D advanced models (multiple layered tissues, organoids, etc.), and multicompartmentalized tissue models
This book provides an up-to-date account of the technologies, organizations and dynamics which constitute the digital economy, and assesses the impacts they have on regions and communities.
No longer merely a subspecialty, pediatric anesthesia is now a professional entity in its own right, as is amply demonstrated in this comprehensive addition to the medical and surgical literature. Pediatric Anesthesia: Basic Principles-State of the Art-Future comprises the contributions of 150 experts in the field from all over the world, providing this book with a truly global perspective. This textbook will help anesthesiologists already interested in pediatric anesthesia to the knowledge and skills inherent to the safe practice of anesthesia for infants and children.
Taking a symptom-oriented approach, this book focuses on the radiographic changes of malformation syndromes and skeletal dysplasias. Its clear structure makes it an essential, practical guide for radiologists, geneticists, and pediatricians.
States and explains the principles underpinning safe, personalized, and dignified nursing home practice using an integrated, cooperative approach. This title reflects the International Association for Geriatrics and Gerontology's conviction that nursing home practice is an interdisciplinary endeavor that requires a sound theoretical, scientific, and values base in addition to clinical expertise. Mindful of the influences of different culture and context, the premise of this text is that there is a shared and common knowledge base to guide nursing home practice and approaches to caring that are universal. --From publisher description.
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