Multilevel Structural Equation Modeling by Bruno Castanho Silva, Constantin Manuel Bosancianu, and Levente Littvay serves as a minimally technical overview of multilevel structural equation modeling (MSEM) for applied researchers and advanced graduate students in the social sciences. As the first book of its kind, this title is an accessible, hands-on introduction for beginners of the topic. The authors predict a growth in this area, fueled by both data availability and also the availability of new and improved software to run these models. The applied approach, combined with a graphical presentation style and minimal reliance on complex matrix algebra guarantee that this volume will be useful to social science graduate students wanting to utilize such models.
Multilevel Structural Equation Modeling serves as a minimally technical overview of multilevel structural equation modeling (MSEM) for applied researchers and advanced graduate students in the social sciences. As the first book of its kind, this title is an accessible, hands-on introduction for beginners of the topic. The authors predict a growth in this area, fueled by both data availability and also the availability of new and improved software to run these models. The applied approach, combined with a graphical presentation style and minimal reliance on complex matrix algebra guarantee that this volume will be useful to social science graduate students wanting to utilize such models.
This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route. - Updated information regarding the most recent in vitro models to study the permeability of drugs - Short and concise chapters covering all the biological barriers with interest in drug permeability - A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models - Simple and clear scientific content, adaptable for young scientists and experimented researchers
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