Boasting a worldwide reputation as the leading text in allergy and immunology, Middleton's Allergy continues its steadfast tradition of providing comprehensive coverage of state-of-the-art basic science, as well as authoritative guidance on the clinical concepts of day-to-day diagnosis and management of allergic disorders. Offering timely information that’s suited for clinicians and researchers alike, Middleton’s is a user-friendly and versatile source for the knowledge you need to provide optimal care to your patients! "A valuable source of reference and pre-sifted information ...the editors are to be commending in keeping the book up-to-date and clinically valuable." Reviewed by: Imnunology News, March 2015 Stay on top of continuous new developments in clinical allergy and immunology through online access to the Expert Consult site, which will feature regular updates as well as the fully searchable contents. Find all of the information you need quickly and easily with a glossary of allergy and immunology terms; highlighted key points for each chapter; hundreds of crystal-clear images with a full-color format, and access to relevant websites. Apply the latest scientific knowledge and clinical applications with new chapters on Innate and Adaptive Immunity, Immune Tolerance, Immunobiology of IgE and Its Receptors, Resolution of Allergic Inflammation, and Particulate and Allergen Interactions, plus sweeping updates throughout. Take full advantage of the major advances in asthma pathogenesis and management with significant updates on diagnosis, treatment, and special aspects of asthma. Obtain the best results from the newest therapeutics for allergic and immunologic diseases through an expanded discussion of immunotherapy that includes new chapters on Sublingual Immunotherapy, Biologics and Immunosuppressives in Asthma, and Alternative and Complementary Therapies.
The authors describe mostly in non-technical language the development of a new scientific paradigm based on nonlinear deterministic dynamics and fractal geometry. The concepts from these two mathematical disciplines are interwoven with data from the physical, social and life sciences. In this way rather sophisticated mathematical concepts are made accessible through experimental data from various disciplines, and the formalism is relegated to appendices. It is shown that the complexity of natural and social phenomena invariably lead to inverse power law distributions, both in terms of probabilities and spectra. This book tries to show how to think differently about familiar phenomena, such as why the bell-shape curve ought not to be used in teaching or in the characterization of such complex phenomena as intelligence.
Cyber security, encompassing both information and network security, is of utmost importance in today's information age. Cyber Security Standards, Practices and Industrial Applications: Systems and Methodologies details the latest and most important advances in security standards. First, it introduces the differences between information security (covers the understanding of security requirements, classification of threats, attacks and information protection systems and methodologies) and network security (includes both security protocols as well as systems which create a security perimeter around networks for intrusion detection and avoidance). In addition, the book serves as an essential reference to students, researchers, practitioners, and consultants in the area of social media, cyber security and information, and communication technologies (ICT).
This unique resource-the first book of its kind exclusively devoted to the subject-offers timely coverage of the cells, mechanisms, and proteins involved in allergic inflammation, emphasizing the latest advances in local cell recruitment.
In this introductory text the authors look closely at widely held assumptions about ‘race’ and schooling in Britain, and evaluate the role of the school in a multi-ethnic society. Focusing on contemporary issues and concerns, they consider such controversial questions as: Is the education system rigged against black pupils? Is ‘tolerance’ really a characteristic of the British? The volume provides a detailed analysis of the Education Reform Act (1988) and the debate surrounding the National Curriculum, and asks whether these new initiatives do truly open the doors of opportunity for all children.
What do the classification of algebraic surfaces, Weyl's dimension formula and maximal orders in central simple algebras have in common? All are related to a type of manifold called locally mixed symmetric spaces in this book. The presentation emphasizes geometric concepts and relations and gives each reader the "roter Faden", starting from the basics and proceeding towards quite advanced topics which lie at the intersection of differential and algebraic geometry, algebra and topology. Avoiding technicalities and assuming only a working knowledge of real Lie groups, the text provides a wealth of examples of symmetric spaces. The last two chapters deal with one particular case (Kuga fiber spaces) and a generalization (elliptic surfaces), both of which require some knowledge of algebraic geometry. Of interest to topologists, differential or algebraic geometers working in areas related to arithmetic groups, the book also offers an introduction to the ideas for non-experts.
This unique resource-the first book of its kind exclusively devoted to the subject-offers timely coverage of the cells, mechanisms, and proteins involved in allergic inflammation, emphasizing the latest advances in local cell recruitment.
This best-selling resource has a worldwide reputation as the leader in its field. Focusing on human immunology and biology, while also reporting on scientific experimentation and advancement, it provides comprehensive coverage of state-of-the-art basic science as well as authoritative guidance on the practical aspects of day-to-day diagnosis and management. This new edition includes 700 full-color illustrations and a new, more accessible format to make finding information a snap for the busy practitioner. Includes a glossary of allergy and immunology for quick and easy reference. Contains keypoints and clinical pearls highlighted to find important information quickly. links to useful online resources both for you and for your patients. Offers contributions from hundreds of international authorities for world-class expertise in overcoming any clinical challenge. Contains 400 new illustrations, 700 in all, to better illustrate complex immunology. Covers the very latest in the field, including hot topics such as food allergy and immunotherapy. Includes the latest guidelines from The National Asthma Education and Prevention Program (NAEPP). Utilizes a new, more user-friendly full-color format for easier reference.
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