Prions are disease-causing agents that are neither bacterial nor fungal nor viral and contain no genetic material. A prion is a protein that occurs normally in a harmless form. By folding into an aberrant shape, the normal prion turns into a rogue agent. It then co-opts other normal prions to become rogue prions. Prions have been held responsible for a number of degenerative brain diseases, including scrapie (a fatal disease of sheep and goats), mad cow disease, Creutzfeldt-Jacob disease, fatal familial insomnia, kuru, an unusual form of hereditary dementia known as Gertsmann-Straeussler-Scheinker disease, and possibly some cases of Alzheimer's disease. This book presents the latest research in this dynamic field.
This book argues for the importance of considering social class in critical psychological enquiry. It provides a historical overview of psychological research and theorising on social class and socio-economic status; before examining the ways in which psychology has contributed to the surveillance, regulation and pathologisation of the working-class ‘Other’. The authors highlight the cost of recent austerity policies on mental health and warn against the implementation of further austerity measures in the current climate The book pulls together perspectives from critical social psychology, feminist psychology, sociology and other critical research which examines the discursive production of social class, classism and classed identities. The authors explore social class in educational and occupational settings, and analyse the intersections between class and other social categories such as gender, race, ethnicity and sexuality. Finally, they consider key issues in debates around social class in the broader social sciences, such as the limitations of approaches informed by poststructuralist theory. This book will be a useful resource for both academics and students studying class from a critical perspective.
Understanding Clinical Papers is a popular and well established introduction to reading clinical papers. It unravels the process of evidence-based practice, using real papers to illustrate how to understand and evaluate published research, and provides clear explanations of important research-related topics.
Communicative Civic-ness explores how political culture shapes social media interactions in civic participation, arguing that social media usage is informed by context-specific civil and political culture. Drawing on cutting-edge research, the book develops a new robust theoretical and conceptual framework on civic engagement and participation, comprising: contextual ethos of civic communication; political culture and civic communication; use of social media in private and public spheres; design of social media. It critically addresses issues within the concept of political culture and develops the concept of ‘communicative civic-ness’. This concept seeks to aid a better-informed debate about the capacity of social media to support the pluralistic discussions that underpin deliberative democratic processes. This book appeals to both undergraduate and postgraduate students, as well as academics with an interest in areas including (but not limited to) sociology, political science and media studies. It will also provide useful information and understanding to third sector organisations and policy-makers regarding forms of civic participation.
A critical introduction to the key processes and contexts of social change in contemporary society, combining a thorough grounding of key theorists with hot topics such the media, the environment and new technologies - ideal for students across the social sciences.
A holistic guide to improving your gut flora for better physical and emotional health • Explores the influence of the gut microbiome and the mesentery on all other bodily systems, especially the brain and immune system • Explains the central role of the digestive system in Ayurveda and traditional Chinese medicine and how these systems treat the microbiome • Presents herbal remedies, acupuncture and acupressure techniques, and dietary methods to restore balance to your gut flora, including a microbiome reset In traditional medicine, such as Indian Ayurveda and Chinese medicine, the digestive system and microbiome are recognized as the foundation for good health. Our internal flora influences our immune system, brain function, hormonal balance, cravings, sleep, mood, inflammatory response, digestion, nutrient assimilation, and elimination. In this holistic guide to cultivating a healthy microbiome and managing gut health naturally, Bridgette Shea explores digestive functioning from the perspectives of both Western science and traditional medicine. She examines Ayurvedic and Chinese medicine principles on digestion and constitution types. She reveals how, in addition to describing what we now call the microbiome, traditional Chinese medicine also has long recognized the importance of an abdominal organ that modern science has only recently acknowledged: the mesentery, the tissues that connect and support the internal organs. Going beyond probiotics and prebiotics, the author presents practices from Ayurveda and Chinese medicine to reestablish balance in your internal microbiome, support the mesentery, improve digestion and elimination, and restore a clear mind and strong immune system. She explains how to read your symptoms, from brain fog and fatigue to congestion and stool quality, and offers herbal remedies, acupuncture and acupressure techniques, and dietary methods to improve your internal health, including a microbiome dietary reset. Revealing the diverse role that our inner microbial colonies play in keeping us happy and healthy, this book shows that by changing your microbiome, you can greatly improve your physical, emotional, and mental health.
A soup-to-nuts overview of just what it takes to successfully design, develop and manage an online game. Learn from the top two online game developers through the real-world successes and mistakes not known to others. There are Case studies from 10+ industry leaders, including Raph Koster, J. Baron, R. Bartle, D. Schubert, A. Macris, and more! Covers all types of online games: Retail Hybrids, Persistent Worlds, and console games. Developing Online Games provides insight into designing, developing and managing online games that is available nowhere else. Online game programming guru Jessica Mulligan and seasoned exec Bridgette Patrovsky provide insights into the industry that will allow others entering this market to avoid the mistakes of the past. In addition to their own experiences, the authors provide interviews, insight and anecdotes from over twenty of the most well-known and experienced online game insiders. The book includes case studies of the successes and failures of today's most well-known online games. There is also a special section for senior executives on how to budget an online game and how to assemble the right development and management teams. The book ends with a look at the future of online gaming: not only online console gaming (Xbox Online, Playstation 2), but the emerging mobile device game market (cell phones, wireless, PDA).
27 VIEWS of RALEIGH: The City of Oaks in Prose & Poetry features the work of twenty-seven (plus two) Raleighites who create a literary montage of North Carolina's capital city in fiction, essays, and poetry. Novelists, poets, essayists, journalists, and even a science fiction writer capture the city in a variety of genres—spanning neighborhoods, generations, cultural and racial experiences, historic eras—reflecting the social, historic, and creative fabric of Raleigh. As Wilton Barnhardt writes in the book's introduction, “We seem to have flourished not because we have solved all the problems of the New South, despite leading the way now and again, but because we the citizens of Raleigh decided to be erudite, cultured, enriched, and entertained . . .
With Reg Scarlett,When did Michael Holding publicly condemn the,bouncer? Which West Indian batting star could have,played for England? Some of the many less,well-known facts to be found in Lawrence's,excellent anthology, tracing the rise of,West Indian Test cricket from its beginnings at,Lords in 1928, to the ""golden era"" of the 1980's.
Reception studies have made film audiences increasingly visible, while surveys track trends and policymakers gather information about audience preferences and demographics. But little attention has been paid to the specific contextual relationships and interactions between films and individuals that generate and sustain audiences. This monograph develops the idea of audiences as interactive and relational, introducing three innovative concepts: ‘personal film journeys’, five types of audience formations and five geographies of film provision. A major challenge of audience research is how to capture the richness of people’s social and cultural engagement with film. To achieve this, the book uses an innovative mixed-methods research and computational ontology. It develops ground-breaking theory and concepts and an innovative methodology based on an extensive data-set derived from the under-researched area of British regional film audiences.
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