Brian Segarini's Books

A Belly Buff Duff Shared His Stuff

By: Brian Segarini

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A Belly Buff Duff Shared His Stuff

By: Brian Segarini

“A Belly Buff Duff Shared his Stuff” is a story about two gentlemen who are determined to confront each other over a pointless argument. These two individuals find themselves headed for disappointment until they discover a new idea, at least to themselves, which is to share. This new idea leads to a new way of viewing each other. Not as combatants, but as team players who can work together.

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Xlibris Corporation

Published Date

ISBN 10

1984578472

ISBN 13

9781984578471

Cartilage Molecular Aspects

By: Brian K. Hall,Stuart A. Newman

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Cartilage Molecular Aspects

By: Brian K. Hall,Stuart A. Newman

Cartilage plays diverse roles as a definitive supporting tissue in some organs, the basis of low friction surfaces in joints, and a transient morphogenetic template during embryogenesis and repair of the skeleton. The versatility of cartilage is derived from the remarkable material properties of its extracellular matrix, the wide spectrum of regulatory systems that influence the synthesis and degradation of the unique molecular constituents of this matrix, and the development and growth of the cells that produce it. This book touches on each of these areas and provides the first comprehensive reviews of the molecular biology of the genes specifying the collagenous and noncollagenous proteins of the cartilage matrix, as well as the biophysical-chemical properties of the matrix that suits it to the various functions it performs. Up-to-date critical reviews of the mineralization and degradation of cartilage matrix, the roles of polypeptide growth and inducing factors, of ions, in the regulation of cartilage growth and development, and the unique requirements of the energy metabolism of cartilage as a nonvascular tissue, make this volume a useful source for concepts and results for the multiple disciplines that play a part in modern cartilage research.

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Page Count

280

Publisher

CRC Press

Published Date

ISBN 10

0849388171

ISBN 13

9780849388170

Therapeutic Modulation of Cytokines

By: M. W. Bodmer,Brian Henderson

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Therapeutic Modulation of Cytokines

By: M. W. Bodmer,Brian Henderson

Cytokines are peptide or protein cell-to-cell signaling molecules that play vital roles in normal cell and tissue homeostasis, as well as in responses to infectious agents. Because of their importance in virtually all forms of pathology, the pharmaceutical industry is devoting great effort to develop methods for the control of cytokine synthesis or action. This is the first volume to bring together experts from academia and the pharmaceutical industry to discuss problems and solutions in the therapeutic control of cytokines. An introductory section reviews the biology, physiology, and pathology of cytokines. Internationally recognized scientists then discuss the development of low molecular mass inhibitors, including inhibitors of cytokine convertases and oligonucleotide drugs. The potential use of natural inhibitors such as soluble receptors, interleukin-1 receptor antagonists, and anti-cytokine antibodies is detailed. This interesting book also covers intracellular signaling pathways induced by pro-inflammatory cytokines and the bio-modulatory activity of specific cytokines such as TGF-ß. Therapeutic Modulation of Cytokines will interest academic scientists in biochemistry, cell biology, pharmacology, and molecular biology and biological scientists in the pharmaceutical and biopharmaceutical industries.

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Page Count

362

Publisher

CRC Press

Published Date

ISBN 10

0849383811

ISBN 13

9780849383816

Some Lives of Brian

By: Brian Stuart

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Some Lives of Brian

By: Brian Stuart

An only child living in Aldershot, Brian Stuart has always been in touch with the arts. When his father was called up to the army in 1940 his mother decided to take in boarders who performed weekly in the Hippodrome.

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Page Count

137

Publisher

Pen Press

Published Date

ISBN 10

190717284X

ISBN 13

9781907172847

Book's by Brian Segarini

A Belly Buff Duff Shared His Stuff

A Belly Buff Duff Shared His Stuff

Cartilage Molecular Aspects

Cartilage Molecular Aspects

Therapeutic Modulation of Cytokines

Therapeutic Modulation of Cytokines

Some Lives of Brian

Some Lives of Brian

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