Brian M. Dale's Books

In-Vitro Fertilization

By: Kay Elder,Brian Dale

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This extensively updated new edition provides an indispensable account of modern in-vitro fertilization practice, building upon the popularity of previous editions. The authors initially give a comprehensive review of the biology of human gametes and embryos, before outlining basic to advanced IVF techniques. New developments in practical techniques and understanding are discussed, including in-vitro maturation, vitrification, preservation of fertility for cancer patients, stem cell technology, preimplantation genetic testing, and the role of epigenetics and imprinting. The revised introduction also incorporates a 'refresher' study review of fundamental principles of cell and molecular biology, now updated with current knowledge of meiosis in human oocytes, embryo metabolism and basic principles of genome editing. With high-quality illustrations and extensive, up-to-date reading lists, it is a must-have textbook for trainee and practising embryologists, as well as clinicians who are interested in the scientific principles that underpin successful IVF.

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Page Count

399

Publisher

Cambridge University Press

Published Date

ISBN 10

1108607411

ISBN 13

9781108607414

MRI

Basic Principles and Applications

By: Brian M. Dale,Mark A. Brown,Richard C. Semelka

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MRI

Basic Principles and Applications

By: Brian M. Dale,Mark A. Brown,Richard C. Semelka

This fifth edition of the most accessible introduction to MRI principles and applications from renowned teachers in the field provides an understandable yet comprehensive update. Accessible introductory guide from renowned teachers in the field Provides a concise yet thorough introduction for MRI focusing on fundamental physics, pulse sequences, and clinical applications without presenting advanced math Takes a practical approach, including up-to-date protocols, and supports technical concepts with thorough explanations and illustrations Highlights sections that are directly relevant to radiology board exams Presents new information on the latest scan techniques and applications including 3 Tesla whole body scanners, safety issues, and the nephrotoxic effects of gadolinium-based contrast media

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Page Count

248

Publisher

John Wiley & Sons

Published Date

ISBN 10

1119012945

ISBN 13

9781119012948

The Zero Night

A Jonathan Stride Novel

By: Brian Freeman

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The Zero Night

A Jonathan Stride Novel

By: Brian Freeman

“Freeman’s Bourne novels might get more publicity, but his Stride novels are where his skills as a storyteller are really showcased. First-rate.” — Booklist A woman has been kidnapped.Now Jonathan Stride must decide if her husband wants her back ... dead or alive. After nearly dying of a gunshot wound, Jonathan Stride has been on leave from the Duluth Police for more than a year. When his partner, Maggie Bei, gets called about a suspicious abduction involving a local lawyer, she tells Stride it’s time for him to come back. Attorney Gavin Webster says he paid $100,000 in ransom money to the men who kidnapped his wife. Now they’ve disappeared with the cash, and she’s still missing. Gavin claims to be desperate to find her—but Stride discovers that the lawyer had plenty of motive to be the mastermind behind the crime. Even as Stride digs for the truth about Gavin Webster and his wife, he must also deal with a crisis in his own marriage. His wife, Serena, is struggling after the death of her mother, the abusive woman she hadn’t seen in twenty-five years. When she loses control at a crime scene and draws her gun on a fellow cop, Serena finds herself kicked off the Webster case. Alone at her desk, she begins hunting through old police files and starts to ask questions about a mother’s death that was written off as suicide. That death haunts Serena like an echo of her own childhood—but her obsession with it takes a terrible toll. As Serena shuts him out of her despair, and his own investigation grows increasingly tangled, Stride wonders whether going back to his detective work was the right decision. But all he can do is keep moving forward. Because Stride fears the Webster kidnapping may be only one part of a horrific murder conspiracy. And it’s not over yet.

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Page Count

317

Publisher

Blackstone Publishing

Published Date

ISBN 10

1094082368

ISBN 13

9781094082363

Fertilization

The Beginning of Life

By: Brian Dale

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Fertilization

The Beginning of Life

By: Brian Dale

This book introduces readers to the fascinating interaction of specialized gamete cells, forming the early embryo and a blueprint of new life. Readers will gain a thorough understanding of the complex physiological events and mechanical processes - such as ionic regulation, metabolism and intracellular signalling - to decipher cause and effect in fertilization. Wide-ranging in its approach, this book describes fertilization as a highly conserved mechanism throughout the animal kingdom, taking case studies from echinoderms, ascidians, amphibians and mammals through to other phyla. An excellent companion to undergraduate and postgraduate students of medicine, veterinary and biological sciences, this text provides an underpinning of the mechanisms of fertilization that inform assisted reproduction practice and research in medicine and agriculture. It explores the detailed phases before fertilization: the oocyte as a quiescent cell, attracting its partner gamete, followed by a cascade of pre-determined physiological events, to form the dynamic zygote cell; setting the scene for the early embryo, and beyond.

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