Brian J McParland's Books

Medical Radiation Dosimetry

Theory of Charged Particle Collision Energy Loss

By: Brian J McParland

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Medical Radiation Dosimetry

Theory of Charged Particle Collision Energy Loss

By: Brian J McParland

Accurate radiation dosimetry is a requirement of radiation oncology, diagnostic radiology and nuclear medicine. It is necessary so as to satisfy the needs of patient safety, therapeutic and diagnostic optimisation, and retrospective epidemiological studies of the biological effects resulting from low absorbed doses of ionising radiation. The radiation absorbed dose received by the patient is the ultimate consequence of the transfer of kinetic energy through collisions between energetic charged particles and atoms of the tissue being traversed. Thus, the ability of the medical physicist to both measure and calculate accurately patient dosimetry demands a deep understanding of the physics of charged particle interactions with matter. Interestingly, the physics of charged particle energy loss has an almost exclusively theoretical basis, thus necessitating an advanced theoretical understanding of the subject in order to apply it appropriately to the clinical regime. Each year, about one-third of the world's population is exposed to ionising radiation as a consequence of diagnostic or therapeutic medical practice. The optimisation of the resulting radiation absorbed dose received by the patient and the clinical outcome sought, whether diagnostic or therapeutic, demands accuracy in the evaluation of the radiation absorbed doses resulting from such exposures. This requirement arrises primarily from two broadly-encompassing factors: The requirement in radiation oncology for a 5% or less uncertainty in the calculation and measurement of absorbed dose so as to optimise the therapeutic ratio of the probabilities of tumour control and normal tissue complications; and The establishment and further refinement of dose reference levels used in diagnostic radiology and nuclear medicine to minimise the amount of absorbed dose for a required degree of diagnostic benefit. The radiation absorbed dose is the outcome of energetic charged particles decelerating and transferring their kinetic energy to tissue. The calculation of this energy deposition, characterised by the stopping power, is unique in that it is derived entirely from theoretical principles. This dominant role of the associated theory makes its understanding of fundamental to the calculation of the radiation absorbed dose to the patient. The theoretical development of charged particle energy loss recognised in medical physics textbooks is in general limited to basic derivations based upon classical theory, generally a simplified form of the Bohr theory. More advanced descriptions of, for example, the Bethe-Bloch quantum result usually do not go beyond the simple presentation of the result without full explanation of the theoretical development of the theory and consideration of its limitations, its dependencies upon the Born perturbation theory and the various correction factors needed to correct for the failures of that Born theory at higher orders. This is not appropriate for a full understanding of the theory that its importance deserves. The medical radiation physicist should be aware of the details of the theoretical derivations of charged particle energy loss in order to appreciate the levels of accuracy in tabular data provided in reports and the calculation methodologies used in modern Monte Carlo calculations of radiation dosimetry.

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643

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Springer Science & Business Media

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ISBN 10

1447154037

ISBN 13

9781447154037

Nuclear Medicine Radiation Dosimetry

Advanced Theoretical Principles

By: Brian J McParland

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Nuclear Medicine Radiation Dosimetry

Advanced Theoretical Principles

By: Brian J McParland

Complexities of the requirements for accurate radiation dosimetry evaluation in both diagnostic and therapeutic nuclear medicine (including PET) have grown over the past decade. This is due primarily to four factors: Growing consideration of accurate patient-specific treatment planning for radionuclide therapy as a means of improving the therapeutic benefit, development of more realistic anthropomorphic phantoms and their use in estimating radiation transport and dosimetry in patients, Design and use of advanced Monte Carlo algorithms in calculating the above-mentioned radiation transport and dosimetry which require the user to have a thorough understanding of the theoretical principles used in such algorithms, their appropriateness and their limitations, increasing regulatory scrutiny of the radiation dose burden borne by nuclear medicine patients in the clinic and in the development of new radiopharmaceuticals, thus requiring more accurate and robust dosimetry evaluations. An element common to all four factors is the need for precise radiation dosimetry in nuclear medicine, which is fundamental to the therapeutic success of a patient undergoing radionuclide therapy and to the safety of the patients undergoing diagnostic nuclear medicine and PET procedures. As the complexity of internal radiation dosimetry applied to diagnostic and therapeutic nuclear medicine increases, this book will provide the theoretical foundations for: enabling the practising nuclear medicine physicist to understand the dosimetry calculations being used and their limitations, allowing the research nuclear medicine physicist to critically examine the internal radiation dosimetry algorithms available and under development; and providing the developers of Monte Carlo codes for the transport of radiation resulting from internal radioactive sources with the only comprehensive and definitive.

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633

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Springer Science & Business Media

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ISBN 10

1848821263

ISBN 13

9781848821262

Nuclear Medicine Radiation Dosimetry

Advanced Theoretical Principles

By: Brian J McParland

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Nuclear Medicine Radiation Dosimetry

Advanced Theoretical Principles

By: Brian J McParland

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Solve jigsaw puzzle

Age

Page Count

633

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1848821263

ISBN 13

9781848821262

Medical Radiation Dosimetry

Theory of Charged Particle Collision Energy Loss

By: Brian J McParland

Write a review Read reviews Take a Quiz Solve Book Puzzle

Medical Radiation Dosimetry

Theory of Charged Particle Collision Energy Loss

By: Brian J McParland

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

643

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1447154037

ISBN 13

9781447154037

Book's by Brian J McParland

Medical Radiation Dosimetry

Medical Radiation Dosimetry

Nuclear Medicine Radiation Dosimetry

Nuclear Medicine Radiation Dosimetry

Nuclear Medicine Radiation Dosimetry

Nuclear Medicine Radiation Dosimetry

Medical Radiation Dosimetry

Medical Radiation Dosimetry

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