The Fireward Society of Dorchester and Milton was founded in 1793 to protect citizens on both sides of the Neponset River. In 1830, both towns recognized Fountain Engine No. 1 as their main source of fire protection in Milton Village and Lower Mills. Later the Hydrant Engine Company was formed in East Milton, reflecting the population growth in this area. When Milton officials recognized that their fire department could not keep up with the growing town, a chemical engine was purchased and installed in a new firehouse built in the center of Milton in 1881. Soon the town acquired a steam engine and installed it in an even larger station. Thus began the gradual development of a professional, full-time fire department in Milton.
Hormonal carcinogenesis is an important and controversial area of current research. In addition to accelerating existing cancers, can hormones play the role of primary carcinogens? How do genetic factors influence hormone-related cancer risk? Hormones, Genes, and Cancer addresses these questions. Over the past few decades, cancer research has focused on external environmental causes(e.g., tobacco smoke, viruses, asbestos). With the advent of new genetic sequencing techniques, we are just now beginning to understand how the body's internal environment(i.e., the hormones and growth factors that determine normal development) influences cancer etiology and prevention. From molecular insights to clinical analyses, this volume provides state-of-the-art information on the complex interactions between hormones and genes and cancer. The epidemiology and molecular endocrinology of prostate, breast, uterine, ovarian and testicular cancer are detailed in this timely treatise.
This ninth annual edition of Vital Signs takes the world's pulse by compiling a wide-ranging collection of trends that identify both problems and progress in the quest for a sustainable society. It highlights both alarming situations and encouraging developments. Part One is a comprehensive presentation of the key indicators in areas such as food, agriculture, energy, atmosphere, economics, transport and the military. Part Two provides in-depth special feature articles on: environmental features, such as transgenic crops and paper recycling; economic features, such as environmental taxes and corporate mergers; and social features, such as tuberculosis, prisons and women in politics.
Essentials in Total Hip Arthroplasty by Dr. Javad Parvizi is a succinct, yet comprehensive text that provides a unique and colorful look into the world of total hip arthroplasty, an in-depth history of this common procedure, as well as strategies to treat and prevent complications. Inside you will find information on: • Patient selection • Preoperative templating • Surgical techniques • Relevant anesthesia and pain management • Postoperative rehabilitation • Strategies for minimization of complications • Relevant figures and diagrams • And much more Essentials in Total Hip Arthroplasty is unique in its format to provide basic and detailed information on total hip arthroplasty from A to Z with descriptive, easy-to-read text and extensive visual elements, such as charts and tables. With total hip arthroplasty being the most successful and popular procedure and each chapter being written by both a resident and an attending, Essentials in Total Hip Arthroplasty will be the essential “go-to” text for residents, fellows, physical therapists, students, and junior attendings involved with all matters related to the procedure.
Heme oxygenase is an enzyme which breaks down heme, the iron-containing oxygen-carrying constituent of the red blood cells. Heme must be synthesised and degraded within an individual nucleated cell, as heme is essential for the maintenance of cellular homeostasis by sensing or using oxygen. Physiological heme degradation is catalysed by the two functional isozymes of heme oxygenase, heme oxygenase-1 (HO-1) and HO-2, yielding CO, iron, and biliverdin IX N. Heme oxygenase-1 (HO-1), has potent anti-inflammatory, anti-oxidant and anti-proliferative effects, is up-regulated by multiple stimuli and provides protection against oxidative stress. HO-1 also plays an important role in the regulation of cardiovascular function and is involved in many other diseases such as sickle cell disease. This new book brings together leading research from around the world in this field.
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