Examination of the bone marrow has always been, and to-date techniques whose application will undoubtedly to a large extent still is, within the domain of the haema increase in the future. tologist. This is because smears of bone marrow aspirates After lengthy discussions and enquiries, the conclusion together with peripheral blood films and results of other was reached that the magnifications of most of the tests and investigations provided the information on which illustrations could be omitted without detracting from the usefulness of the Atlas. The magnifications used are the clinical diagnosis was based. Recently, the widespread availability of both improved indicated in Fig. 1.25. In addition, not every detail specif biopsy needles and techniques for processing has greatly ically indicated in a figure or its legend is necessarily increased the number of routinely taken bone biopsies mentioned in the text; and often a range of observations and placed the examination of bone marrow biopsy is illustrated and in these cases the legends are self sectiors also in the field of histopathology - so that explanatory. this Atlas is one of the Current Histopathology series. This Atlas is directed to haematologists and to histo Therefore, the haematologist and the histopathologist pathologists and to anyone interested in the investigation now complement each other in the interpretation of bone and understanding of the human bone marrow. marrow smears, imprints and sections, thus utilizing all available information and expertise to arrive at a diagnosis.
-As the population ages, the incidence of osteoporosis, and the interest in it, will continue to grow -A practical guide for all physicians that includes all you need to know about osteoporosis -Includes easy-to-follow guidelines for lifelong maintenance of skeletal structure and function -Easy to read, up-beat and optimistic with a touch of humor
This comprehensive book, lavishly illustrated with over 700 colour pictures, addresses the subject of bone in internal medicine. It is based on biopsies of bone and first describes the normal range of physiological findings in iliac crest biopsies in young, middle-aged and elderly individuals. The book then deals systematically with the osseous disorders most frequently encountered in internal medicine, and some that would be considered in the differential diagnosis. Numerous up-to-date references are included. The clinical applications of biopsies of bone are emphasized as well as their clinical interpretation; sections on histomorphometry and functional aspects of bone cells are also included. The book will be of particular interest to specialists in internal medicine, endocrinology, nephrology, haematology and oncology, as well as being a bench manual for the practising pathologist.
Bones are everybody’s business. This means that clinical osteology, now an independent specialty, nevertheless encompasses all branches of medicine and affects each and every one of us. Intended for doctors who seek precise information on bisphosphonates in medical practice, this book has been designed as an up-to-date manual to deal with the currently recognized indications for bisphosphonates, to outline situations and conditions for prevention of skeletal disorders, and to provide practical guidelines for treatment.
Osteoporosis is a global threat because it can impact every human being as they age. In this new edition, the authors point out the enormous scale of the problem in terms of human suffering, morbidity and mortality on the one hand, and the astronomical national costs on the other. Written in an easy-to-read style, this book updates physicians on the current knowledge about bone structure, physiology and pathology, with an emphasis on the diagnosis, therapy and prevention of osteoporosis. Its purpose is to educate members of the medical profession about this widespread and potentially disabling disease, while providing information on related current evidence-based medicine. The book covers everything from basic physiology to osteoporosis diagnosis, including utility of specialized tests and current treatment recommendations, and will provide the primary care physician with sound medical knowledge in the prevention and management of osteoporosis. It is up-beat and optimistic, with a touch of humor; it is scientifically based but provides easy-to-follow guidelines for lifelong maintenance of skeletal structure and function. Osteoporosis is preventable if doctors want it to be, and every doctor can contribute. Bone is every doctor's and every body's business.
Osteoporosis is indeed a global threat because every human being is vulnerable and subject to it as time goes by. The authors point out the enormous scale of the problem in terms of human suffering, morbidity and mortality on the one hand and the astronomical national costs on the other. The book is up-beat and optimistic with a touch of humour; it is scientifically based but provides easy-to-follow guidelines for lifelong maintenance of skeletal structure and function. Osteoporosis is preventable, if doctors want to, and every doctor can contribute. Bone is every doctor's and every body's business.
The potential capacity of the biphosphonates to intervene in osseous remodeling was recognized more than 30 years ago. The biphosphonates inhibit osteoclastic activity. In spite of advances in early detection, surgey, chemo-and radiotherapy, metastatic bone disease is still a major and in many cases intractable clinical problem. The biphosphonates are now the most effective agents in the management of bone metastases - as shown by trials in patients with breast and prostate cancer, and in multiple myeloma. Bone pain, new ostelytic events and pathologic fractures are decreased and complications associated with these events are avoided. Existing osteolytic lesions may even be reversed. New fields of indications of biphosphonates are shown to be in the adjuvant therapy of breast cancer and in stage 1 multiple myeloma to prevent skeletal destruction and also to inhibit tumor growth. Over the past few years the biphosphonates have proved their value also in many other conditions such as Paget's disease of bone, osseous disorders with an osteoclastic component leading to osteopenia/osteoporosis, in congenial, endocrine and metabolic disorders. Perhaps, for the future and for the next millennium the most widespread and extensive use to these anti-osteoclastic component leading to osteopenia/osteoporosis, in congenial, endocrine and metabolic disorders. Perhaps, for the future and for the next millennium the most widespread and extensive use to these anti-osteoclastic agents will be in these disorders, and particularly in so-called primary osteoporosis which evenually effects anyone who lives long enough, causing widespread morbidity with drastic economic consequences both individually and nationally. The authors' aim is to provide an office and desk companion - comprehensive, concise, practical for easy reference - an up-to-date guide for prevention and therapy of skeletal complications whenever and wherever they occur in general and specialized medical practice.
Bones are everybody’s business. This means that clinical osteology, now an independent specialty, nevertheless encompasses all branches of medicine and affects each and every one of us. Intended for doctors who seek precise information on bisphosphonates in medical practice, this book has been designed as an up-to-date manual to deal with the currently recognized indications for bisphosphonates, to outline situations and conditions for prevention of skeletal disorders, and to provide practical guidelines for treatment.
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