Advanced Planning Systems (APS) are a key enabler of the supply chain management. However, APS are highly complex and difficult to comprehend. This book provides students with valuable insights into the capabilities of state-of-the-art APS and bridges the gap between theory (model building and solution algorithms), software implementation, and adaptation to a specific business case. Our business case – named Frutado – provides a unifying framework for illustrating the different planning tasks that arise in a company – from demand planning to the distribution of goods – that are addressed by APS. In addition, the book guides through interactive learning units which have been created and recorded for each module of SAP ́s APS. Learning units can be downloaded free of charge ready to be displayed in a web browser. Together, the textbook and the learning units provide the required skills to better understand the concepts, models, and algorithms underlying today ́s APS.
Volker Schlöndorff’s Cinema: Adaptation, Politics and the “Movie-Appropriate”examines the work of major postwar Germandirector Volker Schlöndorff in historical, economic, and artistic contexts. . In spite of Schlöndorff’s successes with films like The Lost Honor ofKatharina Blum and The Tin Drum, as well as his acclaimed work in the U.S. with Death of a Salesman, Gathering of Old Men and The Handmaid’s Tale, this is the first in-depthcritical study of the filmmaker’s career.
This book analyzes the impact of migration on the lives of multiple generations of 2000 Turkish families. Exploring education, marriage, fertility, friends, attitudes and religiosity, it reveals transformations and continuities in the lives of migrants and their families in Europe when compared to their non-migrant counterparts in Turkey.
Visualization in Medicine is the first book on visualization and its application to problems in medical diagnosis, education, and treatment. The book describes the algorithms, the applications and their validation (how reliable are the results?), and the clinical evaluation of the applications (are the techniques useful?). It discusses visualization techniques from research literature as well as the compromises required to solve practical clinical problems. The book covers image acquisition, image analysis, and interaction techniques designed to explore and analyze the data. The final chapter shows how visualization is used for planning liver surgery, one of the most demanding surgical disciplines. The book is based on several years of the authors' teaching and research experience. Both authors have initiated and lead a variety of interdisciplinary projects involving computer scientists and medical doctors, primarily radiologists and surgeons.* A core field of visualization and graphics missing a dedicated book until now* Written by pioneers in the field and illustrated in full color* Covers theory as well as practice
This book provides the most complete formal specification of the semantics of the Business Process Model and Notation 2.0 standard (BPMN) available to date, in a style that is easily understandable for a wide range of readers – not only for experts in formal methods, but e.g. also for developers of modeling tools, software architects, or graduate students specializing in business process management. BPMN – issued by the Object Management Group – is a widely used standard for business process modeling. However, major drawbacks of BPMN include its limited support for organizational modeling, its only implicit expression of modalities, and its lack of integrated user interaction and data modeling. Further, in many cases the syntactical and, in particular, semantic definitions of BPMN are inaccurate, incomplete or inconsistent. The book addresses concrete issues concerning the execution semantics of business processes and provides a formal definition of BPMN process diagrams, which can serve as a sound basis for further extensions, i.e., in the form of horizontal refinements of the core language. To this end, the Abstract State Machine (ASMs) method is used to formalize the semantics of BPMN. ASMs have demonstrated their value in various domains, e.g. specifying the semantics of programming or modeling languages, verifying the specification of the Java Virtual Machine, or formalizing the ITIL change management process. This kind of improvement promotes more consistency in the interpretation of comprehensive models, as well as real exchangeability of models between different tools. In the outlook at the end of the book, the authors conclude with proposing extensions that address actor modeling (including an intuitive way to denote permissions and obligations), integration of user-centric views, a refined communication concept, and data integration.
Visualization, Visual Analytics and Virtual Reality in Medicine: State-of-the-art Techniques and Applications describes important techniques and applications that show an understanding of actual user needs as well as technological possibilities. The book includes user research, for example, task and requirement analysis, visualization design and algorithmic ideas without going into the details of implementation. This reference will be suitable for researchers and students in visualization and visual analytics in medicine and healthcare, medical image analysis scientists and biomedical engineers in general. Visualization and visual analytics have become prevalent in public health and clinical medicine, medical flow visualization, multimodal medical visualization and virtual reality in medical education and rehabilitation. Relevant applications now include digital pathology, virtual anatomy and computer-assisted radiation treatment planning. - Combines visualization, virtual reality and analytics - Written by leading researchers in the field - Gives the latest state-of-the-art techniques and applications
This book presents a proposal for designing business process management (BPM) systems that comprise much more than just process modelling. Based on a purified Business Process Model and Notation (BPMN) variant, the authors present proposals for several important issues in BPM that have not been adequately considered in the BPMN 2.0 standard. It focusses on modality as well as actor and user interaction modelling and offers an enhanced communication concept. In order to render models executable, the semantics of the modelling language needs to be described rigorously enough to prevent deviating interpretations by different tools. For this reason, the semantics of the necessary concepts introduced in this book are defined using the Abstract State Machine (ASM) method. Finally, the authors show how the different parts of the model fit together using a simple example process, and introduce the enhanced Process Platform (eP2) architecture, which binds all the different components together. The resulting method is named Hagenberg Business Process Modelling (H-BPM) after the Austrian village where it was designed. The motivation for the development of the H-BPM method stems from several industrial projects in which business analysts and software developers struggled with redundancies and inconsistencies in system documentation due to missing integration. The book is aimed at researchers in business process management and industry 4.0 as well as advanced professionals in these areas.
Written with the advanced undergraduate in mind, this book introduces into the field of Bioinformatics. The authors explain the computational and conceptional background to the analysis of large-scale sequence data. Many of the corresponding analysis methods are rooted in evolutionary thinking, which serves as a common thread throughout the book. The focus is on methods of comparative genomics and subjects covered include: alignments, gene finding, phylogeny, and the analysis of single nucleotide polymorphisms (SNPs). The volume contains exercises, questions & answers to selected problems.
Recent technological advances have enabled comprehensive determination of the molecular composition of living cells. The chemical interactions between many of these molecules are known, giving rise to genome-scale reconstructed biochemical reaction networks underlying cellular functions. Mathematical descriptions of the totality of these chemical interactions lead to genome-scale models that allow the computation of physiological functions. Reflecting these recent developments, this textbook explains how such quantitative and computable genotype-phenotype relationships are built using a genome-wide basis of information about the gene portfolio of a target organism. It describes how biological knowledge is assembled to reconstruct biochemical reaction networks, the formulation of computational models of biological functions, and how these models can be used to address key biological questions and enable predictive biology. Developed through extensive classroom use, the book is designed to provide students with a solid conceptual framework and an invaluable set of modeling tools and computational approaches.
Visual Computing for Medicine, Second Edition, offers cutting-edge visualization techniques and their applications in medical diagnosis, education, and treatment. The book includes algorithms, applications, and ideas on achieving reliability of results and clinical evaluation of the techniques covered. Preim and Botha illustrate visualization techniques from research, but also cover the information required to solve practical clinical problems. They base the book on several years of combined teaching and research experience. This new edition includes six new chapters on treatment planning, guidance and training; an updated appendix on software support for visual computing for medicine; and a new global structure that better classifies and explains the major lines of work in the field. - Complete guide to visual computing in medicine, fully revamped and updated with new developments in the field - Illustrated in full color - Includes a companion website offering additional content for professors, source code, algorithms, tutorials, videos, exercises, lessons, and more
This self-contained textbook covers fundamental aspects of sequence analysis in evolutionary biology, including sequence alignment, phylogeny reconstruction, and coalescent simulation. It addresses these aspects through a series of over 400 computer problems, ranging from elementary to research level, to enable learning by doing. Students solve the problems in the same computational environment used for decades in science – the UNIX command line. This is available on all three major operating systems for PCs: Microsoft Windows, Mac-OSX, and Linux. To learn using this powerful system, students analyze sample sequence data by applying generic tools, bioinformatics software, and over 40 programs specifically written for this course. The solutions for all problems are included, making the book ideal for self-study. Problems are grouped into sections headed by an introduction and a list of new concepts and programs. By using practical computing to explore evolutionary concepts and sequence data, the book enables readers to tackle their own computational problems.
In this thesis, Bernhard Schmidt describes his research into two fields in the chemical sciences: supramolecular and macromolecular chemistry. Schmidt first investigates cyclodextrins (CDs), which are well known for the formation of supramolecular host/guest complexes with hydrophobic molecules in aqueous solution. Schmidt then also examines reversible addition-fragmentation chain transfer (RAFT) polymerization as a well-suited toll for the synthesis of water-soluble end-functionalized polymers. The author skillfully combines both concepts as a powerful tool to access reversibly forming macromolecular architectures. The novel methods and architectures presented in this work are highly interesting from both a fundamental point of view as well as a basis for the design of efficient drug release systems. The work in this thesis has led to a number of publications in top peer-reviewed journals.
Presents a cumulative index to volumes one through sixteen of "Grzimek's Animal Life Encyclopedia," which provide a wide range of information on various orders and families of animals.
Advanced Planning Systems (APS) are a key enabler of the supply chain management. However, APS are highly complex and difficult to comprehend. This book provides students with valuable insights into the capabilities of state-of-the-art APS and bridges the gap between theory (model building and solution algorithms), software implementation, and adaptation to a specific business case. Our business case – named Frutado – provides a unifying framework for illustrating the different planning tasks that arise in a company – from demand planning to the distribution of goods – that are addressed by APS. In addition, the book guides through interactive learning units which have been created and recorded for each module of SAP ́s APS. Learning units can be downloaded free of charge ready to be displayed in a web browser. Together, the textbook and the learning units provide the required skills to better understand the concepts, models, and algorithms underlying today ́s APS.
The complexity of distribution systems is augmented by various trends: globalization of the manufacturing industry, rising customer demands, and the reverse flows within closed-loop systems. In this light, the need for ‘advanced’ planning methods that are based on quantitative optimization is constantly increasing. This book takes up the challenges posed by these developments. In doing so, it presents recent results and case studies from a group of researchers that regularly meet at the IWDL (International Workshop on Distribution Logistics). The text covers the design of distribution networks, vehicle routing, warehousing and reverse logistics. It also contains a comprehensive review of more than 60 case studies in reverse logistics.
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