Despite an overall decrease in tobacco use, lung cancer (80–85% of which is non-small-cell lung cancer [NSCLC]) is still the leading cause of cancer death in both men and women worldwide. Annual low-dose CT screening of high-risk individuals has the potential to detect early-stage tumors, which can usually be successfully treated with a combination of surgery, radiotherapy and chemotherapy and, in some cases, targeted therapy. However, most patients with NSCLC still present with advanced or metastatic disease. For these patients, initial therapy is guided by the tumor’s molecular characteristics and patient’s performance status. Targeted therapies have significantly improved clinical outcomes and, for some patients with no targetable genetic alterations, immunotherapy has demonstrated significant overall survival benefit. This insightful guide is designed to bring you up to speed with the latest developments and is important reading for all health professionals and medical trainees working in this fast-moving field. Table of Contents: • Prevention and screening • Diagnosis and staging • Surgery • Radiotherapy • Systemic therapy in non-metastatic NSCLC • Systemic therapy in advanced-stage/metastatic disease without a molecular driver • Personalized treatment in advanced NSCLC • Oligometastatic disease and brain metastases
This book provides a concise but rigorous appraisal about the future of nuclear power and the presumed nuclear renaissance. It does so by assessing the technical, economic, environmental, political, and social risks related to all aspects of the nuclear fuel cycle, from uranium mills and mines to nuclear reactors and spent fuel storage facilities. In each case, the book argues that the costs of nuclear power significantly outweigh its benefits. It concludes by calling for investments in renewable energy and energy efficiency as a better path towards an affordable, secure, and socially acceptable future.The prospect of a global nuclear renaissance could change the way that energy is produced and used the world over. Sovacool takes a hard look at who would benefit — mostly energy companies and manufacturers — and who would suffer — mostly taxpayers, those living near nuclear facilities, and electricity customers. This book is a must-read for anyone even remotely concerned about a sustainable energy future, and also for those with a specific interest in modern nuclear power plants.
In this history of right-wing politics in Brazil during the Cold War, Benjamin Cowan puts the spotlight on the Cold Warriors themselves. Drawing on little-tapped archival records, he shows that by midcentury, conservatives--individuals and organizations, civilian as well as military--were firmly situated in a transnational network of right-wing cultural activists. They subsequently joined the powerful hardline constituency supporting Brazil's brutal military dictatorship from 1964 to 1985. There, they lent their weight to a dictatorship that, Cowan argues, operationalized a moral panic that conflated communist subversion with manifestations of modernity, coalescing around the crucial nodes of gender and sexuality, particularly in relation to youth, women, and the mass media. The confluence of an empowered right and a security establishment suffused with rightist moralism created strongholds of anticommunism that spanned government agencies, spurred repression, and generated attempts to control and even change quotidian behavior. Tracking how limits to Cold War authoritarianism finally emerged, Cowan concludes that the record of autocracy and repression in Brazil is part of a larger story of reaction against perceived threats to traditional views of family, gender, moral standards, and sexuality--a story that continues in today's culture wars.
As an important industry, transportation costs account for a considerable percentage of the gross national product of countries. It is therefore key to have at the disposal of those concerned with transportation activities, a bibliographical literature on costs and costing. The bibliography lists books, papers, technical reports, journal articles, and information rarely found in books and dissertations.
This book offers a comprehensive assessment of the dynamics driving, and constraining, nuclear power development in Asia, Europe and North America, providing detailed comparative analysis. The book formulates a theory of nuclear socio-political economy which highlights six factors necessary for embarking on nuclear power programs: (1) national security and secrecy, (2) technocratic ideology, (3) economic interventionism, (4) a centrally coordinated energy stakeholder network, (5) subordination of opposition to political authority, and (6) social peripheralization. The book validates this theory by confirming the presence of these six drivers during the initial nuclear power developmental periods in eight countries: the United States, France, Japan, Russia (the former Soviet Union), South Korea, Canada, China, and India. The authors then apply this framework as a predictive tool to evaluate contemporary nuclear power trends. They discuss what this theory means for developed and developing countries which exhibit the potential for nuclear development on a major scale, and examine how the new "renaissance" of nuclear power may affect the promotion of renewable energy, global energy security, and development policy as a whole. The volume also assesses the influence of climate change and the recent nuclear accident in Fukushima, Japan, on the nuclear power industry's trajectory. This book will be of interest to students of energy policy and security, nuclear proliferation, international security, global governance and IR in general.
This book explores changes in houses and households in the southeastern United States from the Woodland to the Historic Indian Period (ca. 200 B.C. to A.D. 1800). Most studies of domestic architecture in the Southeast have been conducted at the single-site scale. As a result, broader spatial and temporal patterns of variation in houses and households are not well understood. To address this problem, Steere constructed a database that catalogues the architectural features of 1,258 structures from 65 sites in the Southern Appalachian region and surrounding areas. Significant trends identified by this comparative study include changes in the size and spacing of houses, changes in architectural investment, and a secular trend toward the increasing segmentation of houses. Using a theoretical framework developed from household archaeology and anthropology, Steere argues that certain aspects of this architectural variation can be explained by changes in household economics and household composition, symbolic behavior, status differentiation, and settlement patterning. More generally, he proposes that large-scale patterns of diachronic and synchronic variation in domestic architecture are best explained by changes in social organization"--Provided by publisher.
The author presents a comprehensive historical examination of the early Christian graeco-latin translations of the biblical 'apocrypha' and 'pseudepigrapha'. The analysis of the translation techniques employed yields a distinction between 'literal' and 'adaptive' translations on the hand and translations associated with the textual tradition of the bible and those not associated with it. Whereas the former can be distinguished by the respective handling of textual macrostructures, the latter 'biblical' translations were subject to constant revision according to their original and thus always display a number of different versions. Als erster Schritt hin zu einer Geschichte der christlichen Übersetzungsliteratur werden hier die lateinischen Übersetzungen griechisch erhaltener „Apokryphen“ und „Pseudepigraphen“ erstmals umfassend historisch einzuordnen versucht und einer übersetzungstechnischen Analyse unterzogen. Obwohl keine dieser Übersetzungen wirklich sklavisch wörtlich vorgeht, ergibt sich dabei doch ein relativ deutlicher Unterschied zwischen ‚wörtlichen‘ und ‚literarischen‘ Übersetzungen einerseits und mit der biblischen Überlieferung assoziierten und nicht damit assoziierten andererseits: Lassen sich die ersteren beiden primär anhand ihres Umgangs mit textlichen Makrostrukturen auseinanderhalten, zeichnet sich die biblische Überlieferung durch ständig neue Rückbindung einer Übersetzung an ihr Original in Form unterschiedlicher Revisionen aus.
Braniff Airways: Flying Colors takes readers on a magical flight through the history of Braniff International Airways, beginning with its small-town Oklahoma roots to its high-flying and stylish span of the globe. Braniff brought together the mystery of aviation with the glamorous fields of fashion, art, and design, and taught the flying world how to fly with style and beauty. It is this remarkable joining of forces that has made Braniff as popular today as it was when flying in style across the Atlantic and Pacific.
A comprehensive introductory text with more than 150 color images and figures, The Foundations of Shoulder and Elbow Surgery provides essential information on shoulder and elbow care for students, residents, fellows, and new doctors. Surgery of the shoulder and elbow has grown more common in recent decades as understanding of anatomy, physiology, and pathology has improved. Additionally, innovations in surgical techniques and implant design have given surgeons the tools to address a higher number of shoulder and elbow pathologies. To adequately care for this increasing patient population, the basics of shoulder and elbow care must be disseminated to those in training. Together with their expert contributors, Drs. Surena Namdari, Benjamin Zmistowski, and Reza Omid explore the foundational concepts of shoulder and elbow surgery, including: Shoulder anatomy and physical examination, shoulder instability, and rotator cuff disease Frozen shoulder (adhesive capsulitis) and injuries to the biceps-labral complex Shoulder arthritis (glenohumeral arthritis), shoulder fractures, and the athlete’s shoulder and elbow Scapular disorders and acromioclavicular disorders Elbow anatomy and physical exam, elbow instability, and tendon injuries Neuropathies of the upper extremity Elbow arthritis, fractures of the elbow, and humeral shaft fractures In conjunction with clinical experience, The Foundations of Shoulder and Elbow Surgery will serve as an invaluable resource for orthopedic surgeons-in-training.
This comprehensive resource is edited by experts at the Mayo Clinic--a world-renowned center for echocardiography. In this revision, the editors plan to incorporate new imaging strategies in the diagnosis of congenital heart disease in both peds and adult populations. In particular, more detail on 3-D echo, information on the proper usage of TEE, and the increasing importance of followup MRI will be presented. Based on reviewer comments, the editors will include more MRI angiograms, more detailed information on prosthetic valve and posttransplant care, and more correlative anatomic examples in relevant chapters.
Welcome to the3 Books To Knowseries, our idea is to help readers learn about fascinating topics through three essential and relevant books. These carefully selected works can be fiction, non-fiction, historical documents or even biographies. We will always select for you three great works to instigate your mind, this time the topic is:Social Novel: Sybil - Benjamin Disraeli Les Misérables - Victor Hugo Germinal - Émile Zola Social novel is a work of fiction in which a social problem is dramatized through its effect on the characters. Usually a social novel limits itself to exposure of a problem. A personal solution may be arrived at by the novel's characters, but the author does not insist that it can be applied universally or that it is the only one. Benjamin Disraeli's Sybil is one of the first social-problem novels. Sibyl deals with the social and economic disparity between the rich and the poor as a result of the Industrial Revolution. Les Misérables is the magnum opus of the French writer Victor Hugo. It narrates the French political and social situation in the Democratic Uprising. The book draws a critical parallel to the material development of society and the consequent exclusion of poor people. Germinal is Zola's masterpiece and one of the most significant novels in the French tradition. The story takes place in France during a strike caused by the reduction of wages. To compose Germinal, the author spent two months working as a miner in the extraction of coal. Zola describes the principle of the political and trade union organization of the working class, such as the existing divisions between Marxists and anarchists. This is one of many books in the series 3 Books To Know. If you liked this book, look for the other titles in the series, we are sure you will like some of the topics.
This book applies concepts from ethics, justice, and political philosophy to five sets of contemporary energy problems cutting across time, economics, politics, geography, and technology. In doing so, the authors derive two key energy justice principles from modern theories of distributive justice, procedural justice, and cosmopolitan justice. The prohibitive principle states that "energy systems must be designed and constructed in such a way that they do not unduly interfere with the ability of people to acquire those basic goods to which they are justly entitled." The affirmative principle states that "if any of the basic goods to which people are justly entitled can only be secured by means of energy services, then in that case there is also a derivative entitlement to the energy services." In laying out and employing these principles, the book details a long list of current energy injustices ranging from human rights abuses and energy-related civil conflict to energy poverty and pervasive and growing negative externalities. The book illustrates the significance of energy justice by combining the most up-to-date data on global energy security and climate change, including case studies and examples from the electricity supply, transport, and heating and cooking sectors, with appraisals based on centuries of thought about the meaning of justice in social decisions.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.