Moments as projections of an image’s intensity onto a proper polynomial basis can be applied to many different aspects of image processing. These include invariant pattern recognition, image normalization, image registration, focus/ defocus measurement, and watermarking. This book presents a survey of both recent and traditional image analysis and pattern recognition methods, based on image moments, and offers new concepts of invariants to linear filtering and implicit invariants. In addition to the theory, attention is paid to efficient algorithms for moment computation in a discrete domain, and to computational aspects of orthogonal moments. The authors also illustrate the theory through practical examples, demonstrating moment invariants in real applications across computer vision, remote sensing and medical imaging. Key features: Presents a systematic review of the basic definitions and properties of moments covering geometric moments and complex moments. Considers invariants to traditional transforms – translation, rotation, scaling, and affine transform - from a new point of view, which offers new possibilities of designing optimal sets of invariants. Reviews and extends a recent field of invariants with respect to convolution/blurring. Introduces implicit moment invariants as a tool for recognizing elastically deformed objects. Compares various classes of orthogonal moments (Legendre, Zernike, Fourier-Mellin, Chebyshev, among others) and demonstrates their application to image reconstruction from moments. Offers comprehensive advice on the construction of various invariants illustrated with practical examples. Includes an accompanying website providing efficient numerical algorithms for moment computation and for constructing invariants of various kinds, with about 250 slides suitable for a graduate university course. Moments and Moment Invariants in Pattern Recognition is ideal for researchers and engineers involved in pattern recognition in medical imaging, remote sensing, robotics and computer vision. Post graduate students in image processing and pattern recognition will also find the book of interest.
Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
Lonely Planet's Pocket Prague is your guide to the citys best experiences and local life - neighbourhood by neighbourhood. Amble through the winding alleys of the Old Town, explore magnificent Prague Castle, and find the best coffee and cake; all with your trusted travel companion. Uncover the best of Prague and make the most of your trip! Inside Lonely Planet's Pocket Prague: Up-to-date information - all businesses were rechecked before publication to ensure they are still open after 2020s COVID-19 outbreak Full-colour maps and travel photography throughout Highlights and itineraries help you tailor a trip to your personal needs and interests Insider tips to save time and money and get around like a local, avoiding crowds and trouble spots Essential info at your fingertips - hours of operation, phone numbers, websites, transit tips, prices Honest reviews for all budgets - eating, sightseeing, going out, shopping, hidden gems that most guidebooks miss User-friendly layout with helpful icons, and organised by neighbourhood to help you pick the best spots to spend your time Covers Hradcany, Mala Strana, Stare Mesto, Nove Mesto, Petrin Hill, Old Town Square, Wenceslas Square, Vinohrady, Zizkov and more The Perfect Choice: Lonely Planet's Pocket Prague, an easy-to-use guide filled with top experiences - neighbourhood by neighbourhood - that literally fits in your pocket. Make the most of a quick trip to Prague with trusted travel advice to get you straight to the heart of the city. Looking for a comprehensive guide that recommends both popular and off-the-beaten-path experiences, and extensively covers all of Prague & Czechia? Check out Lonely Planet's Prague & Czechia guide. About Lonely Planet: Lonely Planet is a leading travel media company, providing both inspiring and trustworthy information for every kind of traveller since 1973. Over the past four decades, we've printed over 145 million guidebooks and grown a dedicated, passionate global community of travellers. You'll also find our content online, and in mobile apps, videos, 14 languages, armchair and lifestyle books, ebooks, and more. 'Lonely Planet guides are, quite simply, like no other.' New York Times 'Lonely Planet. It's on everyone's bookshelves; it's in every traveler's hands. It's on mobile phones. It's on the Internet. It's everywhere, and it's telling entire generations of people how to travel the world.' Fairfax Media (Australia)
Chefs from 136 restaurants along the coastline of Oregon and Washington, across the Striat of Juan de Fuca, to the Canadian border, including Seattle and Portland for the first time, share with you some of their favorite recipes.
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