Managing Dual Diagnosis in the Family A Mother's Story An Uphill Struggle is an insightful and heart warming blend of memoir and research as a mother sifts through past attempting to understand the devastating connection between ADD and Chemical Addiction (Dual Diagnosis) as it played out in life and death of her two sons. It speaks from the heartof their struggles with the undiagnosed and untreatable disorder of ADD and their attempts to self medicate to normalize their turbulent minds. With great honesty and sensitivity, An Uphill Struggle reaches out to parents locked in a tangle of circumstances that seems at times, beyond their control and understanding.
This is the second of three volumes of Methods in Molecular Biology that deal with Physical Methods of Analysis. The first of these, Spectroscopic Methods and Analyses dealt with NMR spec troscopy, mass spectrometry, and metalloprotein techniques, and the third will cover X-ray crystallographic methods. As with the first volume. Microscopy, Optical Spectroscopy, and Macroscopic Techniques is intended to provide a basic understand ing for the biochemist or biologist who needs to collaborate with spe cialists in applying the techniques of modern physical chemistry to biological macromolecules. The methods treated in this book fall into four groups. Part One covers microscopy, which aims to visualize individual molecules or complexes of several molecules. Electron microscopy is the more familiar of these, while scanning tunneling microscopy is a new and rapidly developing tool. Methods for determining the shapes and sizes of molecules in solution are described in Part Two, which includes chapters on X-ray and neutron scattering, light scattering, and ult- centrifugation. Calorimetry, described in Part Three, provides the means to monitor processes involving thermodynamic changes, whether these are intramolecular, such as conformational transition, or the interactions between solutes or between a solute and its sol vent. Part Four is concerned with optical and infrared spectroscopy and describes applications ranging from the measurement of protein concentration by UV absorbance to the analysis of secondary struc ture using circular dichroism and Fourier-transform infrared spec troscopy.
The Pirate Queen begins in Ireland with the infamous Grace O’Malley, a ruthless pirate and scourge to the most powerful fleets of sixteenth-century Europe. This Irish clan chieftain, sea captain, and pirate queen was a contemporary of Elizabeth I, a figure whose life is the stuff of myth. Regularly raiding English ships caught off Ireland’s west coast, O’Malley was purported to have fought the Spanish armada just hours after giving birth to her son. She had several husbands in her lifetime, and acquired lands and castles that still dot the Irish coastline today. But Grace O’Malley was not alone. Since ancient times, women have rowed and sailed, commanded and fished, built boats and owned fleets. As pirate, captain’s wives, lighthouse keepers and sailors in disguise they’ve explored coastlines and set off alone across unknown seas. Yet their incredible contributions have been nearly erased from the history books. In The Pirate Queen, Barbara Sjoholm brings some of these extraordinary women back to life, taking the reader on an unforgettable journey from the wild Irish coast to the haunting Scandinavian fjords in this meticulously researched, colorfully written, and truly original work
Published by Oxford University Press in 2008, Massacre at Mountain Meadows relied on new and exhaustive research to tell the story of one of the grimmest episodes in Latter-day Saint history. On September 11, 1857, southern Utah settlers slaughtered more than 100 emigrants of a California-bound wagon train. In this much-anticipated sequel, Richard E. Turley Jr. and Barbara Jones Brown follow up that volume with an examination of the aftermath of the atrocity. In greater detail than ever before, Vengeance Is Mine documents southern Utah leaders' attempts to cover up their crime by silencing witnesses and spreading lies about the victims and perpetrators of the crime. Investigations by both governmental and church bodies were stymied by stonewalling and political wrangling. While nine men were eventually indicted, five were captured and only one, John D. Lee, was executed. The book examines the maneuvering of the defense and prosecution in Lee's two trials, the second ending in Lee's conviction. The book examines the fraught relationship between Lee and church president Brigham Young, including what Young knew of the crime and when he knew it. The book also tells the story of the seventeen young children who survived the massacre and their later return to Arkansas, from where the ill-fated wagon train originated. The book traces the fate of the perpetrators to the end of their lives, including the harrowing demise of Nephi Johnson, who screamed, "Blood! Blood! Blood!" in the delirium of his death bed more than sixty years after the massacre"--
A modern, comprehensive compilation of more than 7,000 entries covering themes, concepts, and discoveries in archaeology written in nontechnical language and tailored to meet the needs of professionals, students and general readers. The main subject areas include artifacts; branches of archaeology, chronology; culture; features; flora and fauna; geography; geology; language; people; related fields; sites; structures; techniques and methods; terms and theories; and tools.
The benchmark evidence-based pharmacotherapy text-now in full color! Additional chapters are available online When it comes to helping you develop a mastery of evidence-based medicine for optimal patient outcomes, no book can match Pharmacotherapy: A Pathophysiologic Approach. Like the discipline it covers, the scope of this trusted resource goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. The book also delves into psychosocial issues that affect compliance ... topics related to a patient's ability to understand and manage often-complex therapy... and lifestyle changes that may reduce the need for drug therapy or improve pharmacotherapeutic outcomes. Pharmacotherapy delivers everything you need to provide safe, efficacious drug therapy across the full range of therapeutic categories. FEATURES NEW! Expanded evidence-based recommendations NEW! Extended coverage of the timely issue of palliative care and pain medicine NEW! Important chapters on Pulmonary Hypertension, Disorders of Calcium and Phosphorus Homeostasis, and Multiple Myeloma, Outstanding pedagogy, including: “Key Concepts” highlighted in each chapter “Clinical Presentation” boxes summarize the most common disease signs and symptoms covered in each chapter “Clinical Controversies” boxes-presented in the Treatment sections of the disease-oriented chapters-examine the complicated issues faced by students and clinicians in providing drug therapy Clear therapeutic recommendations in each disease-specific chapter “Evaluation of Therapeutic Outcomes” boxes in each disease-specific chapter, containing key monitoring guidelines that facilitate the development of a pharmaceutical, nursing, or medical care plan
Managing Dual Diagnosis in the Family A Mother's Story An Uphill Struggle is an insightful and heart warming blend of memoir and research as a mother sifts through past attempting to understand the devastating connection between ADD and Chemical Addiction (Dual Diagnosis) as it played out in life and death of her two sons. It speaks from the heartof their struggles with the undiagnosed and untreatable disorder of ADD and their attempts to self medicate to normalize their turbulent minds. With great honesty and sensitivity, An Uphill Struggle reaches out to parents locked in a tangle of circumstances that seems at times, beyond their control and understanding.
Heparins remain amongst the most commonly used drugs in clinical practice. Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.
The animal trainer recounts her Dublin childhood, her travels, her marriage, and her experiences as a dog trainer, horse breaker, importer of polo ponies, author, and television personality
The animal trainer recounts her Dublin childhood, her travels, her marriage, and her experiences as a dog trainer, horse breaker, importer of polo ponies, author, and television personality
The author wishes it to be known that the content of this book is authentic and true - messages sent from the Spirit World by Matthew's wife Barbara. When she passed over into the spiritual realms, that could have been the end of the book but Barbara is s
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