In this insiders account of university science in America, Barbara Migeon focuses on how an influx of new technologies empowered scientists to make groundbreaking discoveries on the nature of hereditary diseases. She begins her story with an account of how she began her research career before delving into a broader discussion of what scientists do, what they must deal with, and the changing face of biomedical science over the last half century. This is a fascinating, insightful and thought-provoking book, beautifully written by an excellent scientist, a pioneering female in a strongly male-centric field. Her personal history of this remarkable era of biomedical science is a must read for anyone males, females, scientists and non-scientists curious about the process of scientific discovery and progress toward gender equity. Her account shows how science is shaped by deep commitment and insights, complex human interactions, and public policy. Barbara Sollner-Webb. Professor Emerita, Department of Biological Chemistry, The Johns Hopkins University I was captivated by Migeons ability to synthesize the personal, political, scientific, and academic strands of her life over the past half-century. To her credit, this historian speaks forthrightly; while her research clearly has been a source of deep joy, she also exposes the institutional problems (including sexism). Her inclusion of selected material from a personal journal she kept over the years is a welcome addition to a book that offers a fresh perspective to scientists as well as non-scientists, men as well as women. Evelyn Torton Beck, Professor Emerita, Womens Studies, University of Maryland
This is the only book about the X chromosome as a key to female development and the role of X-related factors in the etiology of sex differences in human disease. This new edition reflects research advances from the six years since the widely praised first edition.
In this insiders account of university science in America, Barbara Migeon focuses on how an influx of new technologies empowered scientists to make groundbreaking discoveries on the nature of hereditary diseases. She begins her story with an account of how she began her research career before delving into a broader discussion of what scientists do, what they must deal with, and the changing face of biomedical science over the last half century. This is a fascinating, insightful and thought-provoking book, beautifully written by an excellent scientist, a pioneering female in a strongly male-centric field. Her personal history of this remarkable era of biomedical science is a must read for anyone males, females, scientists and non-scientists curious about the process of scientific discovery and progress toward gender equity. Her account shows how science is shaped by deep commitment and insights, complex human interactions, and public policy. Barbara Sollner-Webb. Professor Emerita, Department of Biological Chemistry, The Johns Hopkins University I was captivated by Migeons ability to synthesize the personal, political, scientific, and academic strands of her life over the past half-century. To her credit, this historian speaks forthrightly; while her research clearly has been a source of deep joy, she also exposes the institutional problems (including sexism). Her inclusion of selected material from a personal journal she kept over the years is a welcome addition to a book that offers a fresh perspective to scientists as well as non-scientists, men as well as women. Evelyn Torton Beck, Professor Emerita, Womens Studies, University of Maryland
This is a detailed study of the illustrations to Amir Khusrau's Khamsah, in which twenty discourses are followed by a brief parable, and four romances. Amir Khusrau (1253-1325) lived the greater part of adventurous life in Delhi; he composed in Persian, and also in Hindi. From the point of view of manuscript illustration, his most important work is his Khamsah (Quintet'). Khusrau's position as a link between cultures of Persia and India means that the early illustrated copies of the Khamsah have a particular interest. The first extant exemplar is from the Persian area in the late 14th century, but a case can be made that work was probably illustrated earlier in India.
Through creative use of examples, case studies and exercises from organizations worldwide, this book demonstrates the many levels at which globalization impacts on contemporary businesses, society and organizations.
Inside the 3rd edition of this esteemed masterwork, hundreds of the most distinguished authorities from around the world provide today's best answers to every question that arises in your practice. They deliver in-depth guidance on new diagnostic approaches, operative technique, and treatment option, as well as cogent explanations of every new scientific concept and its clinical importance. With its new streamlined, more user-friendly, full-color format, this 3rd edition makes reference much faster, easier, and more versatile. More than ever, it's the source you need to efficiently and confidently overcome any clinical challenge you may face. Comprehensive, authoritative, and richly illustrated coverage of every scientific and clinical principle in ophthalmology ensures that you will always be able to find the guidance you need to diagnose and manage your patients' ocular problems and meet today's standards of care. Updates include completely new sections on "Refractive Surgery" and "Ethics and Professionalism"... an updated and expanded "Geneitcs" section... an updated "Retina" section featuring OCT imaging and new drug therapies for macular degeneration... and many other important new developments that affect your patient care. A streamlined format and a new, more user-friendly full-color design - with many at-a-glance summary tables, algorithms, boxes, diagrams, and thousands of phenomenal color illustrations - allows you to locate the assistance you need more rapidly than ever.
This book investigates Jan Van Eyck's patronage by the Crown of Portugal and his role as diplomat-painter for the Duchy of Burgundy following his first voyage to Lisbon in 1428-1429, when he painted two portraits of Infanta Isabella, who became the third wife of Philip the Good in 1430. New portrait identifications are provided for the Ghent Altarpiece (1432) and its iconographical prototype, the lost Fountain of Life. These altarpieces are analysed with regard to King Joao I's conquest of Ceuta, achieved by his sons, who were hailed as an "illustrious generation." Strong family ties between the dynastic houses of Avis and Lancaster explain Lusitania's sustained fascination with Arthurian lore and the Grail quest. Several chapters of this book are overlaid with a chivalric veneer. A second "secret mission" to Portugal in 1437 by Jan van Eyck is postulated and this diplomatic visit is related to Prince Henry the Navigator's expedition to Tangier and King Duarte's attempts to forge an alliance with Alfonso V of Aragon. Late Eyckian commissions are reviewed in the light of this ill-fated crusade and additional new portraits are identified. The most significant artist of Renaissance Flanders appears to have been patronized as much by the House of Avis as by the Duchy of Burgundy. Barbara von Barghahn is Professor of Art History at George Washington University and a specialist in the art history of Portugal, Spain, and their colonial dominions, as well as Flanders. In 1993, she was conferred O Grao Comendador in the Portuguese Order of Prince Henry the Navigator. She has spent nearly a decade completing research about Jan van Eyck's diplomatic visits to the Iberian Peninsula.
Managing the Drug Discovery Process, Second Edition thoroughly examines the current state of pharmaceutical research and development by providing experienced perspectives on biomedical research, drug hunting and innovation, including the requisite educational paths that enable students to chart a career path in this field. The book also considers the interplay of stakeholders, consumers, and drug firms with respect to a myriad of factors. Since drug research can be a high-risk, high-payoff industry, it is important to students and researchers to understand how to effectively and strategically manage both their careers and the drug discovery process. This new edition takes a closer look at the challenges and opportunities for new medicines and examines not only the current research milieu that will deliver novel therapies, but also how the latest discoveries can be deployed to ensure a robust healthcare and pharmacoeconomic future. All chapters have been revised and expanded with new discussions on remarkable advances including CRISPR and the latest gene therapies, RNA-based technologies being deployed as vaccines as well as therapeutics, checkpoint inhibitors and CAR-T approaches that cure cancer, diagnostics and medical devices, entrepreneurship, and AI. Written in an engaging manner and including memorable insights, this book is aimed at anyone interested in helping to save countless more lives through science. A valuable and compelling resource, this is a must-read for all students, educators, practitioners, and researchers at large—indeed, anyone who touches this critical sphere of global impact—in and around academia and the biotechnology/pharmaceutical industry. - Considers drug discovery in multiple R&D venues - big pharma, large biotech, start-up ventures, academia, and nonprofit research institutes - with a clear description of the degrees and training that will prepare students well for a career in this arena - Analyzes the organization of pharmaceutical R&D, taking into account human resources considerations like recruitment and configuration, management of discovery and development processes, and the coordination of internal research within, and beyond, the organization, including outsourced work - Presents a consistent, well-connected, and logical dialogue that readers will find both comprehensive and approachable - Addresses new areas such as CRISPR gene editing technologies and RNA-based drugs and vaccines, personalized medicine and ethical and moral issues, AI/machine learning and other in silico approaches, as well as completely updating all chapters
Women can be described as genetic mosaics because they have two distinctly different types of cells throughout their bodies. Unlike males, who have one X chromosome (inherited from their mother), females have two X chromosomes in every cell (one from each parent). The fathers copy works in some cells, while the mothers copy works in others. These two X chromosomes often function differently, especially if one carries a defective gene. Much has been written about the Y chromosome and its role in inducing maleness. This will be the first book about the X chromosome as a key to female development and the role of X-related factors in the etiology of sex differences in human disease. Barbara Migeon, from the renowned McKusick-Nathan Institute at Johns Hopkins, is a major figure in clinical genetics and is eminently qualified to write this book, and she writes clearly and effectively. She describes both the underlying molecular mechanisms and the remarkable genetic consequences of X inactivation and its role in determining the biological concepts characteristic of women. Females are Mosaics will be valuable to geneticists, biologists, and all health professionals interested in women's health.
The only gynecology resource that combines a full-color text and a procedural atlas—revised and updated Part medical text, part surgical atlas, Williams Gynecology is written by the renowned team of ob-gyn clinicians at Dallas’ Parkland Hospital who are responsible for the landmark Williams Obstetrics. The new edition of Williams Gynecology maintains the consistent tone, leading-edge clinical insights, and quality illustrations of the successful first edition, while expanding and refreshing its content to keep pace with the most recent developments in this dynamic field. The many important topics covered in Williams Gynecology are evidence-based, yet the book is specifically designed as a practical quick-reference guide, aided throughout by helpful teaching points. Reflecting the latest clinical perspectives and research, the second edition features outstanding new coverage of minimally invasive procedures, robotics, and gynecologic anatomy. Features Two resources in one—full-color medical text and surgical atlas—conveniently surveys the entire spectrum of gynecologic disease, including general gynecology, reproductive endocrinology and infertility, urogynecology, and gynecologic oncology Atlas of gynecologic surgery contains 450 figures that illustrate operative techniques Unique consistent text design for an efficient approach to diagnosis and treatment Strong procedure orientation covers a vast array of surgical operations, which are illustrated in detail Evidence-based discussion of disease evaluation reinforces and supports the clinical relevance of the book’s diagnostic and treatment methods Distinguished authorship from the same Parkland Hospital-based team which edited Williams Obstetrics—the leading reference in obstetrics for more than a century Newly illustrated gynecologic anatomy chapter created with the surgeon in mind to emphasize critical anatomy for successful surgery New coverage of minimally invasive procedures and robotics, the latest procedures in gynecologic oncology, and in-vitro fertilization Numerous illustrations, photographs, tables, and treatment algorithms
The premier reference in obstetrics for more than a century – now even more relevant to today's practice Williams Obstetrics is the most detailed, comprehensive, and rigorously referenced text on the subject. Written by an author team from the world-renowned Parkland Hospital, the hallmarks of this classic are its thoroughness, scientific basis, and practical applicability for the obstetrician at the bedside. This edition of Williams Obstetrics continues to emphasize the scientific-based underpinnings and evidence-based practices of the specialty. This is accomplished by using incorporating more than 3,000 new literature citations and guidelines from the most trusted professional and academic organizations. One of the important features of the twenty-fourth edition is a greater focus on the fetus as a patient and an expanded discussion of fetal diagnosis and therapy. This is complemented by more than 100 new sonographic and MR images of common fetal abnormalities. A new reorganization of the text enables the book to highlight more effectively the myriad disorders that may complicate pregnancy. Williams Obstetrics provides a convenient, clinically relevant text of value to the busy practitioner. The book summarizes important new data that has influenced evidence-based management to improve pregnancy outcomes. Much of this data is conveniently distilled into newly created tables and diagnostic and treatment algorithms. During discussion, numerous sources are cited to provide evidence-based options for patient management. Additionally, nearly 900 images complement the text, many of which are new or enhanced. These include sonograms, MR images, photographs, diagrams, and graphs. This edition of Williams Obstetrics continues to provide clinicians with everything they need to know about the practice of obstetrics with a level of authority and quality of presentation not found in any other resource.
The landmark text that has served generations of obstetrician-gynecologists—fully updated with the most current perspectives of the field A Doody's Core Title for 2023! Williams Obstetrics has defined the discipline for generations of obstetrician-gynecologists. Written by authors from the nationally renowned University of Texas Southwestern Medical Center and Parkland Hospital, the new edition of this authoritative, evidence-based work maintains its trademark comprehensive coverage and applicability at the bedside, while offering the most current information and insights. The culmination of a century of clinical thought, Williams Obstetrics, 26th Edition delivers expert coverage of obstetrical complications, such as preterm labor, pregnancy-related hypertension, infection, and hemorrhage. It additionally offers foundational content on reproductive anatomy, physiology, and prenatal care. The authors have enhanced this edition with 1,000+ full-color illustrations, plus an increased emphasis on the fast-growing subspecialty of Maternal-Fetal Medicine. No other text matches the long-established scientific rigor and accessibility of Williams Obstetrics. With its state-of-the-art design and review of the newest advances and protocols, this not-be-missed clinical companion brings positive outcomes within reach. New and updated content includes: Increased focus on Maternal-Fetal Medicine Greater coverage of hypertension and hemorrhage Deeper insights into in-utero complications Expanded fetal t section includes cutting-edge fetal imaging, genetics, prenatal diagnosis, and fetal disorders and therapy Basic science, physiology of labor, preterm labor updated with contemporaneous publications in the literature More obstetrical sonography figures Eye-catching illustrations, including updated graphs, sonograms, MRIs, photographs, and photomicrographs
The author wishes it to be known that the content of this book is authentic and true - messages sent from the Spirit World by Matthew's wife Barbara. When she passed over into the spiritual realms, that could have been the end of the book but Barbara is s
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.