Atta-ur-Rahman's Books

Studies in Natural Products Chemistry

By: Atta-ur Rahman

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Studies in Natural Products Chemistry

By: Atta-ur Rahman

This volume presents frontier reviews on recent developments on bioactive natural products in cutting-edge areas by eminent experts in their respective fields. Fourteen reviews treat diverse and different topics in natural products chemistry - basic ones, medicinally oriented ones, agro-oriented ones and ecologically oriented ones.It is an important addition to this important series on Natural Products Chemistry, generally acknowledged to be the leading series on this topic.

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1023

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Elsevier

Published Date

ISBN 10

0080569838

ISBN 13

9780080569833

Studies in Natural Products Chemistry

Stereoselective Synthesis (Part J)

By: Atta-ur Rahman

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Studies in Natural Products Chemistry

Stereoselective Synthesis (Part J)

By: Atta-ur Rahman

Studies in Natural Products Chemistry

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772

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Elsevier

Published Date

ISBN 10

008054178X

ISBN 13

9780080541785

Solving Problems with NMR Spectroscopy

By: Atta-ur Rahman,Muhammad Iqbal Choudhary,Atia-tul- Wahab

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Solving Problems with NMR Spectroscopy

By: Atta-ur Rahman,Muhammad Iqbal Choudhary,Atia-tul- Wahab

Solving Problems with NMR Spectroscopy, Second Edition, is a fully updated and revised version of the best-selling book. This new edition still clearly presents the basic principles and applications of NMR spectroscopy with only as much math as is necessary. It shows how to solve chemical structures with NMR by giving many new, clear examples for readers to understand and try, with new solutions provided in the text. It also explains new developments and concepts in NMR spectroscopy, including sensitivity problems (hardware and software solutions) and an extension of the multidimensional coverage to 3D NMR. The book also includes a series of applications showing how NMR is used in real life to solve advanced problems beyond simple small-molecule chemical analysis. This new text enables organic chemistry students to choose the most appropriate NMR techniques to solve specific structures. The problems provided by the authors help readers understand the discussion more clearly and the solution and interpretation of spectra help readers become proficient in the application of important, modern 1D, 2D, and 3D NMR techniques to structural studies. - Explains and presents the most important NMR techniques used for structural determinations - Offers a unique problem-solving approach for readers to understand how to solve structure problems - Uses questions and problems, including discussions of their solutions and interpretations, to help readers understand the fundamentals and applications of NMR - Avoids use of extensive mathematical formulas and clearly explains how to implement NMR structure analysis - Foreword by Nobel Prize winner Richard R. Ernst New to This Edition - Key developments in the field of NMR spectroscopy since the First Edition in 1996 - New chapter on sensitivity enhancement, a key driver of development in NMR spectroscopy - New concepts such as Pulse Field Gradients, shaped pulses, and DOSY (Diffusion Order Spectroscopy) in relevant chapters - More emphasis on practical aspects of NMR spectroscopy, such as the use of Shigemi tubes and various types of cryogenic probes - Over 100 new problems and questions addressing the key concepts in NMR spectroscopy - Improved figures and diagrams - More than 180 example problems to solve, with detailed solutions provided at the end of each chapter

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535

Publisher

Academic Press

Published Date

ISBN 10

0124116132

ISBN 13

9780124116139

Studies in Natural Products Chemistry

Bioactive Natural Products (Part M)

By: Atta-ur Rahman

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Studies in Natural Products Chemistry

Bioactive Natural Products (Part M)

By: Atta-ur Rahman

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The present volume contains 22 articles written by leading experts in natural product chemistry on biologically active natural products. It includes research on a variety of different classes of natural products including sesquiterpenes, quassinoids, diterpenoids, lignans, oligostilbenes, phenylethanoids, phenylpropanoid glycosides, curcumin analogues, glycosphingolipids etc. Many of these have been found to be active in a number of different disease conditions.* Timely reviews written by international authorities in the field* Topics ranging from purely chemical to very biological* The 13th volume in the series to be devoted to bioactive natural products

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1149

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Elsevier

Published Date

ISBN 10

0080458483

ISBN 13

9780080458489

Studies in Natural Products Chemistry

Structure and Chemistry (Part D)

By: Atta-ur Rahman

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Studies in Natural Products Chemistry

Structure and Chemistry (Part D)

By: Atta-ur Rahman

Rapid advances in chromatographic procedures, spectroscopic techniques and pharmacological assay methods have resulted in the discovery of an increasing number of new and interesting natural products from terrestrial and marine sources. The present volume contains comprehensive reviews on some of the major advances in this field which have taken place in recent years. The reviews include those on: novel metabolites from marine gastropods; the chemistry of marine natural products of the Halenaquinol family; secondary metabolites from Echinoderms and Bryozoans; triterpenoids and aromatic compounds from medicinal plants; chemistry and activity of sesquiterpenes from the genus Lactarius; the chemistry of bile alcohols; antifungal sesquiterpene dialdehydes; annonaceous acetogenins; nargenicin macrolides; and lignans and diarylheptanoids. Tropane alkaloids and phenolides formed by root cultures are also reviewed. Articles on natural Diels-Alder type adducts, the use of computer aided overlay for modelling the substrate binding domain of HLADH, applications of 170 NMR spectroscopy to natural product chemistry and the role of biological raw materials in synthesis are included. Volume 17 provides material of interest to natural products chemists.

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680

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Elsevier

Published Date

ISBN 10

0080541984

ISBN 13

9780080541983

Studies in Natural Products Chemistry

Structure and Chemistry (Part F)

By: Atta-ur Rahman

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Studies in Natural Products Chemistry

Structure and Chemistry (Part F)

By: Atta-ur Rahman

Natural Products Chemistry continues to grow at an increasing pace and this growth is reflected in the present volume of Studies in Natural Products Chemistry, which is the 20th of this series. The first 20 volumes were largely devoted to structure and synthesis of various classes of natural products, irrespective of their bioactivity. Subsequent volumes of this series will however be devoted to the chemistry of bioactive natural products and will therefore a departure from the earlier volumes.The present volume contains contributions from a number of eminent scientists and covers interesting reviews on terpenes, alkaloids and other types of natural products reported from terrestrial and marine sources. Comprehensive indexes covering all the 20 volumes have been prepared which include a Cumulative General Subject Index along with more focused Cumulative Indices on Organic Synthesis, Pharmacological Activity and Biological Source. This comprehensive indexing of the volumes should make the entire series much more valuable and user-friendly.

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1365

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Elsevier

Published Date

ISBN 10

0080541992

ISBN 13

9780080541990

Bioactive Natural Products (Part G)

By: Atta-ur Rahman

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Bioactive Natural Products (Part G)

By: Atta-ur Rahman

Bioactive Natural Products (Part G)

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1367

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Elsevier

Published Date

ISBN 10

0080542069

ISBN 13

9780080542065

Studies in Natural Products Chemistry

Stereoselective Synthesis (Part K)

By: Atta-ur Rahman

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Studies in Natural Products Chemistry

Stereoselective Synthesis (Part K)

By: Atta-ur Rahman

In Volume 18 of this well-established series, Professor Atta-ur-Rahman again brings together the work of several of the world's leading authorities in organic chemistry. Their contributions demonstrate the rapid, ongoing development of this field by illustrating many of the latest advances in synthetic methods, total synthesis, structure determination, biosynthetic pathways, and biological activity.The opening chapter presents an overview of strategies for the synthesis of several classes of natural products with an emphasis on complex polycyclic systems. Subsequent chapters discuss the synthesis of specific classes of compounds, including morphine, polyketides, acetogenins, nonactic acid derivatives, complex spirocyclic ethers, ä-lactam and pyridone derivatives, inositol phosphates, sphingolipids, brassinosteroids, Hernandia lignans, and dimeric steroidal pyrazine alkaloids. Finally, the ever stronger links between chemistry and biology are reinforced by chapters on the origin and function of secondary metabolites, bioactive conformations of gastrin hormones, and immunochemistry.

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1109

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Elsevier

Published Date

ISBN 10

0080541771

ISBN 13

9780080541778

Studies in Natural Products Chemistry

Indices Part A

By: Atta-ur- Rahman

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Studies in Natural Products Chemistry

Indices Part A

By: Atta-ur- Rahman

The Studies in Natural Products Chemistry series is a valuable source for researchers and engineers working in natural product and medicinal chemistry. Studies in Natural Products Chemistry Volume 31: Indices Part A encompasses the contents of the previous 30 volumes published in the Studies in Natural Products series. To make searching easier, the book is divided into four separate indices: Cumulative General Subject Index; Cumulative Organic Synthesis Index; Cumulative Pharmacological Activity Index and; Cumulative Biological Source Index, allowing readers to easily locate required information. This volume and the series remain an important addition to any library.* Encompasses the contents of the previous 30 volumes published in the Studies in Natural Products series * The book is divided into four separate indices: Cumulative General Subject Index; Cumulative Organic Synthesis Index; Cumulative Pharmacological Activity Index and; Cumulative Biological Source Index * An important addition to any library

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1371

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Elsevier

Published Date

ISBN 10

0080481205

ISBN 13

9780080481203

Studies in Natural Products Chemistry

Bioactive Natural Products (Part L)

By: Atta-ur- Rahman

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Studies in Natural Products Chemistry

Bioactive Natural Products (Part L)

By: Atta-ur- Rahman

Natural Product Chemistry continues to expand to exciting new frontiers of great importance in medicine. Written by international authorities in various fields of natural product chemistry, this latest volume in the well-established series Studies in Natural Products Chemistry contains 23 chapters, covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases. This present volume, will again be of great interest to research scientists and scholars working in the exciting field of new drug discovery.* Written by international authorities in the various fields of natural product chemistry* Contains 23 comprehensive articles covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases* Valuable source of information for research scientists and scholars in the field of new drug discovery

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1269

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Elsevier

Published Date

ISBN 10

0080458475

ISBN 13

9780080458472

Structure and Chemistry (Part E)

By: Atta-ur Rahman

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Structure and Chemistry (Part E)

By: Atta-ur Rahman

Structure and Chemistry (Part E)

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865

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Elsevier

Published Date

ISBN 10

0080537332

ISBN 13

9780080537337

Frontiers in Anti-Cancer Drug Discovery

By: Atta Ur Rahman

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Frontiers in Anti-Cancer Drug Discovery

By: Atta Ur Rahman

Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery, including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The book series is essential reading for all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

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328

Published Date

ISBN 10

1608058859

ISBN 13

9781608058853

New Advances in Analytical Chemistry, Volume 3

By: Atta-ur Rahman

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New Advances in Analytical Chemistry, Volume 3

By: Atta-ur Rahman

New Advances in Analytical Chemistry, Volume 3 presents recent developments in various spectroscopic techniques such as NMR spectroscopy and mass spectroscopy in the form of comprehensive reviews written by leading authorities in the field. With new and updated information. the book is invaluable to both research students and postdoctoral workers w

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361

Publisher

CRC Press

Published Date

ISBN 10

1482264900

ISBN 13

9781482264906

Frontiers in Clinical Drug Research - Alzheimer Disorders

By: Atta-ur-Rahman

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Frontiers in Clinical Drug Research - Alzheimer Disorders

By: Atta-ur-Rahman

Frontiers in Clinical Drug Research - Alzheimer Disorders is an e-Book series which covers recent topics related to understanding Alzheimer's disease (AD) that causes dementia and has a neurodegenerative effect on the brain. The disease affects memory, thought process, and language of affected individuals. Chapters in each volume focus on (Alzheimer Disorders) drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders. Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in field of Alzheimer’s Disease research. The fifth volume of this series features chapters covering critical discussions on AD management and new therapies. The topics reviewed in this volume include: - Current concepts in management of AD - The amyloid cascade hypothesis and stem cell-based AD therapy - Phytochemicals targeting AD - Dementia screening in primary clinical care settings - Updates in dementia / AD clinical research and drug development

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328

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Bentham Science Publishers

Published Date

ISBN 10

1681082314

ISBN 13

9781681082318

Herbal Medicine: Back to the Future: Volume 2, Vascular Health

By: Ferid Murad,Atta-ur-Rahman,Ka Bian

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Herbal Medicine: Back to the Future: Volume 2, Vascular Health

By: Ferid Murad,Atta-ur-Rahman,Ka Bian

Herbal Medicine: Back to the Future compiles expert reviews on the application of herbal medicines (including Ayurveda, Chinese traditional medicines and alternative therapies) to treat different ailments. The book series demonstrates the use of sophisticated methods to understand traditional medicine, while providing readers a glimpse into the future of herbal medicine. The second volume in the series continues on the theme of the previous volume, focusing on herbal remedies for cardiovascular health. The topics included in this volume are: · Plants used for treating cardiovascular diseases in the Iberian Peninsula and Balearic Islands · Herbal products for treating hypertension and hyperlipidemia · Medicinal plants and the Mediterranean diet for treating obesity related cardiovascular disorders · Traditional Indian cardiovascular medicine This volume is essential reading for all researchers in the field of ethnobotany, natural product chemistry, nutrition and pharmacology. Medical professionals involved in cardiology and internal medicine who seek to improve their knowledge about herbal medicine and alternative therapies will also benefit from the contents of the volume.

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231

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Bentham Science Publishers

Published Date

ISBN 10

9811403732

ISBN 13

9789811403736

Frontiers in Anti-Infective Drug Discovery

By: Atta-ur Rahman,M. Iqbal Choudhary

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Frontiers in Anti-Infective Drug Discovery

By: Atta-ur Rahman,M. Iqbal Choudhary

This eBook series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the eBook series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The fifth volume of this series features 6 chapters that cover the following topics: - Virus infection pathways in living cells - Antimicrobial activity of natural products (essential oils and food products) - Medicinal plants that produce immunomodulators of veterinary interest - In silico approaches for determination of drug targets

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211

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Bentham Science Publishers

Published Date

ISBN 10

1681082918

ISBN 13

9781681082912

Frontiers in Stem Cell and Regenerative Medicine Research

By: Atta-ur- Rahman,Shazia Anjum

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Frontiers in Stem Cell and Regenerative Medicine Research

By: Atta-ur- Rahman,Shazia Anjum

Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. This volume includes reviews on the following topics: -the role of microvesicles and exosomes in mesenchymal stem cell (MSCs) in treating diseases while overcoming side effects -alternative models for understanding cancer stem cell biology -stem cells treatments for orthopaedic injury and endocrine disorders -wound healing biomaterials -theoretical models of hematopoietic cell dynamics (with implications for bone marrow transplants)

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263

Publisher

Bentham Science Publishers

Published Date

ISBN 10

1681085895

ISBN 13

9781681085890

13C-NMR of Natural Products

Volume 1 Monoterpenes and Sesquiterpenes

By: Atta-Ur-Rahman,V.U. Ahmad

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13C-NMR of Natural Products

Volume 1 Monoterpenes and Sesquiterpenes

By: Atta-Ur-Rahman,V.U. Ahmad

Advances in natural product chemistry have led to a large number of drugs, both derived from medicinal plants, marine plants, and animals, and created as synthetic analogues of these sources. This ground-breaking, comprehensive volume presents the latest data on the 13C-NMR of monoterpenes and sesquiterpenes.

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994

Publisher

Springer Science & Business Media

Published Date

ISBN 10

0306438976

ISBN 13

9780306438974

Novel Developments in Pharmaceutical and Biomedical Analysis

By: Atta-ur- Rahman,Sibel A. Ozkan,Rida Ahmed

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Novel Developments in Pharmaceutical and Biomedical Analysis

By: Atta-ur- Rahman,Sibel A. Ozkan,Rida Ahmed

Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents information about a selection of analytical techniques. Readers will find information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. Novel Developments in Pharmaceutical and Biomedical Analysis is the second volume of the series and covers the following topics: o Chromatographic assays of solid dosage forms and their drug dissolution studies o UHPLC method for the estimation of bioactive compounds o HILIC based LC/MS for metabolite analysis o In vitro methods for the evaluation of oxidative stress o Application of vibrational spectroscopy in studies of structural polymorphism of drugs o Electrochemical sensors based on conductive polymers and carbon nanotubes o Optical sensor arrays for pharmaceutical and biomedical analyses o Chemical applications of ionic liquids o New trends in enantioanalysis of pharmaceutical compounds

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466

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Bentham Science Publishers

Published Date

ISBN 10

1681085747

ISBN 13

9781681085746

Bioactive Natural Products (Part D)

V23

By: Atta-ur Rahman

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Bioactive Natural Products (Part D)

V23

By: Atta-ur Rahman

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

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925

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Elsevier

Published Date

ISBN 10

0080542026

ISBN 13

9780080542027

Frontiers in Clinical Drug Research – Anti Allergy Agents

By: Atta-ur-Rahman

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Frontiers in Clinical Drug Research – Anti Allergy Agents

By: Atta-ur-Rahman

Frontiers in Clinical Drug Research - Anti-Allergy Agents is an exciting eBook series comprising a selection of updated review articles relevant to the recent development of pharmacological agents used for the treatment of allergies. The scope of the reviews includes clinical trials of anti-inflammatory and anti-allergic drugs, drug delivery strategies used to treat specific allergies (such as inflammation, asthma and dermatological allergies), lifestyle dependent modes of therapies and the immunological or metabolic mechanisms that are of interest to researchers as targets for new drugs. The first volume of this series sheds light on new therapies that can be employed for allergic reactions in patients (both traditional and non-traditional therapies), nutrition based therapies and the use of substances such as omalizumab and adrenaline to counter inflammatory response and anaphylaxis in patients. Frontiers in Clinical Drug Research - Anti-Allergy Agents will be of interest to immunologists and drug discovery researchers interested in anti-allergic drug therapy as the series provides relevant cutting edge reviews written by experts in this rapidly expanding field.

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389

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Bentham Science Publishers

Published Date

ISBN 10

1608057186

ISBN 13

9781608057184

Bioactive Natural Products (Part E)

V15

By: Atta-ur Rahman

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Bioactive Natural Products (Part E)

V15

By: Atta-ur Rahman

Bioactive Natural Products (Part E)

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595

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Elsevier

Published Date

ISBN 10

0080541976

ISBN 13

9780080541976

Frontiers in Clinical Drug Research- Central Nervous System

By: Atta-ur-Rahman

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Frontiers in Clinical Drug Research- Central Nervous System

By: Atta-ur-Rahman

Frontiers in Clinical Drug Research – Central Nervous System presents the latest researches and clinical studies on the central nervous system (CNS). It covers a range of topics such as the development and pathophysiology of the brain and spinal cord, physiological sites of drug action in the CNS and clinical findings on drugs used to treat CNS defects due to injury or impaired development. In addition to clinical research on humans, the book also highlights other avenues of CNS medicine and research such as pain medicine, stem cell research, pharmacology, toxicology and translational models in animals. The second volume of the series features chapters on the following topics: - Nucleic acids as drugs for neurodegenerative diseases - Cellular Cysteine Network (CYSTEINET): - Non-motor Symptoms in Parkinson’s Disease and drug therapies - Multi-modal pharmacological treatments for major depressive disorder

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247

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Bentham Science Publishers

Published Date

ISBN 10

168108189X

ISBN 13

9781681081892

Studies in Natural Products Chemistry

Bioactive Natural Products (Part F)

By: Atta-ur Rahman

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Studies in Natural Products Chemistry

Bioactive Natural Products (Part F)

By: Atta-ur Rahman

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1051

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Elsevier

Published Date

ISBN 10

0080542034

ISBN 13

9780080542034

Bioactive Natural Products (Part C)

V22

By: Atta-ur Rahman

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Bioactive Natural Products (Part C)

V22

By: Atta-ur Rahman

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796

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Elsevier

Published Date

ISBN 10

0080527833

ISBN 13

9780080527833

Frontiers in Clinical Drug Research - CNS and Neurological Disorders

By: Atta-ur-Rahman

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Frontiers in Clinical Drug Research - CNS and Neurological Disorders

By: Atta-ur-Rahman

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is an eBook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The fourth volume of this series features reviews that cover a variety of topics including: -Multiple sclerosis drug therapy -Treatment of diabetic neuropathy -Migraine treatments -Ischemic stroke treatments

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394

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Bentham Science Publishers

Published Date

ISBN 10

1681082950

ISBN 13

9781681082950

Frontiers in CNS Drug Discovery

By: Atta-ur-Rahman,M. Iqbal Choudhary

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Frontiers in CNS Drug Discovery

By: Atta-ur-Rahman,M. Iqbal Choudhary

“Frontiers in CNS Drug Discovery” is an eBook series devoted to publishing the latest and the most important advances in Central Nervous System (CNS) drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The eBook series should prove to be of interest to all pharmaceutical scientists involved in research in CNS drug design and discovery. Each volume is devoted to the major advances in CNS drug design and discovery. The eBook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.

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433

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Bentham Science Publishers

Published Date

ISBN 10

1608057674

ISBN 13

9781608057672

Bioactive Natural Products (Part B)

V21

By: Atta-ur Rahman

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Bioactive Natural Products (Part B)

V21

By: Atta-ur Rahman

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827

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Elsevier

Published Date

ISBN 10

0080542018

ISBN 13

9780080542010

Studies in Natural Products Chemistry

Stereoselective Synthesis

By: Atta-ur Rahman

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Studies in Natural Products Chemistry

Stereoselective Synthesis

By: Atta-ur Rahman

Studies in Natural Products Chemistry Volume 12: Stereoselective Synthesis (Part H) reviews the stereoselective synthetic and mechanistic chemistry of bicyclomycin. It discusses chemical studies of the taxane diterpenes; the synthetic methodology for 2-amino alcohols of biological interest; and the synthesis and structure of hydroxylated indolizidines. Some of the topics covered in the book are the synthetic routes to the oxahydrindene subunit of the avermectin-milbemycin family of antiparasitic agents; isolation, structure elucidation, biosynthesis, and biological activity of the avermectins; two-stage coupling process of macrolide antibiotics synthesis; and synthesis of the rifamycin S ansa-chain compound. The complete synthesis of erythromycin A is also covered. The role of isocyanides in the synthesis of beta lactam antibiotics and the characteristics of the beta lactam antibiotics are discussed. The development of an A-Ring annulation strategy for taxane synthesis is also presented. A chapter is devoted to the advances in the synthesis of tumor-promoting diterpenes. The book can provide useful information to chemists, biologists, students, and researchers.

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541

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Elsevier

Published Date

ISBN 10

1483193241

ISBN 13

9781483193243

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 7

By: Zareen Amtul

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Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 7

By: Zareen Amtul

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The seventh volume of this series features reviews that cover the following topics related to the treatment of neurodegenerative diseases, epilepsy and stroke: -Fatty Acid Amides as a New Potential Therapeutic Agent in Multiple Sclerosis -Epileptic Seizures Detection Based on Non-Linear Characteristics Coupled with Machine Learning Techniques -Hampering Essential Tremor Neurodegeneration in Essential Tremor: Present and Future Directions -The Potential Therapeutic Role of the Melatoninergic System in Treatment of Epilepsy and Comorbid Depression -Modeling Neurodegenerative Diseases Using Transgenic Model of Drosophila -Genetic Basis in Stroke Treatment: Targets of Potent Inhibitors

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166

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Bentham Science Publishers

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ISBN 10

9811447500

ISBN 13

9789811447501

Urban Disasters and Resilience in Asia

By: Rajib Shaw,Atta-ur-Rahman,Akhilesh Surjan,Gulsan Ara Parvin

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Urban Disasters and Resilience in Asia

By: Rajib Shaw,Atta-ur-Rahman,Akhilesh Surjan,Gulsan Ara Parvin

Urban Disasters and Resilience in Asia presents the latest information on the intensity and frequency of disasters. Specifically, the fact that, in urban areas, more than 50% of the world's population is living on just 2% of the land surface, with most of these cities located in Asia and developing countries that have high vulnerability and intensification. The book offers an in-depth and multidisciplinary approach to reducing the impact of disasters by examining specific evidence from events in these areas that can be used to develop best practices and increase urban resilience worldwide. As urban resilience is largely a function of resilient and resourceful citizens, building cities which are more resilient internally and externally can lead to more productive economic returns. In an era of rapid urbanization and increasing disaster risks and vulnerabilities in Asian cities, Urban Disasters and Resilience in Asia is an invaluable tool for policy makers, researchers, and practitioners working in both public and private sectors. - Explores a broad range of aspects of disaster and urban resiliency, including environmental, economic, architectural, and engineering factors - Bridges the gap between urban resilience and rural areas and community building - Provides evidence-based data that can lead to improved disaster resiliency in urban Asia - Focuses on Asian cities, some of the most densely populated areas on the planet, where disasters are particularly devastating

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370

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Butterworth-Heinemann

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ISBN 10

0128023775

ISBN 13

9780128023778

Anti-Obesity Drug Discovery and Development

By: Atta-ur Rahman,M. Iqbal Choudhary

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Anti-Obesity Drug Discovery and Development

By: Atta-ur Rahman,M. Iqbal Choudhary

Obesity is a complex health problem, caused by a number of factors such as excessive food intake, lack of physical activity, genetic predisposition, endocrine disorders, medications and psychiatric illnesses. Onset of obesity in both the developing and the developed world has reached epidemic proportions. In response to this, efforts to control and treat obesity have also been vigorously pursued, ranging from raising awareness about lifestyle changes to the discovery and development of safe and effective anti-obesity drugs. Anti-obesity Drug Discovery and Development is focused on this very important area of healthcare research. The third volume of this series is dedicated to anti-obesity treatments including updates on new therapeutics for obesity, Nesfatin-1 and its therapeutic uses, the role of proteomics in pediatric anti-obesity treatment, the role of oxidative stress in childhood obesity and a review of data on gut microbiota as a treatment option for obesity.

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245

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Bentham Science Publishers

Published Date

ISBN 10

1681081873

ISBN 13

9781681081878

Topics in Anti-Cancer Research: Volume 8

By: Atta-ur-Rahman,Khurshid Zaman

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Topics in Anti-Cancer Research: Volume 8

By: Atta-ur-Rahman,Khurshid Zaman

Topics in Anti-Cancer Research covers new developments in the field of cancer. Novel drugs as anticancer agents include natural and synthetic phenazines and other anti-cancer compounds. It also encompasses the role of estrogen as endocrine disruptors and strategies targeting cancer stem cells for the treatment of different types of cancers, including myeloma and renal cell cancer. The diversity of researches and topics published in this eBook Series will be valuable to cancer researchers, clinicians, and cancer professionals aiming to develop novel anti-cancer targets for the treatment of various cancers. The topics covered in the eighth volume of this series are as follows: -Novel Drugs for Multiple Myeloma -Synthetic Estrogens are Endocrine Disruptors via Inhibition of AF1 Domain of ERs -Recent Progress of Phenazines as Anticancer Agents -Cancer Stem Cell Targeting for Anticancer Therapy: Strategies and Challenges

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182

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Bentham Science Publishers

Published Date

ISBN 10

9811404372

ISBN 13

9789811404375

Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 4

By: Atta-ur-Rahman

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Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 4

By: Atta-ur-Rahman

Frontiers in Clinical Drug Research – Diabetes and Obesity is an eBook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The fourth volume of this series features 7 chapters: -Pharmacologic Obesity Treatment -Interplay Between Bile Acid and GLP-1 Receptor Agonist Signaling Informs the Design of Drugs to Combat Obesity and its Metabolic Complications -Sodium–Glucose Co-Transporters Inhibitors for Type 2 Diabetes Mellitus -The Effects of Traditional Chinese Medicine on Inflammatory Cytokines in Diabetic Nephropathy -Through the Perspective of Histology – The Alzheimer’s Disease Promotion by Obesity and Glucose Metabolism: Type 3 Diabetes -Pharmacological Mechanism of PPARγ Ratio in Diabetes and Obesity -Hydrogen Sulfide and Carbohydrate Metabolism

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280

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Bentham Science Publishers

Published Date

ISBN 10

1681084457

ISBN 13

9781681084459

Anti-Angiogenesis Drug Discovery and Development

By: M. Iqbal Choudhary

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Anti-Angiogenesis Drug Discovery and Development

By: M. Iqbal Choudhary

The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, etc. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results. Anti-angiogenesis Drug Discovery and Development provides is an excellent compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two recent decades. The feast of these reader-friendly reviews on topics of great scientific importance – many of which are considered significant medical breakthroughs, makes this book excellent reading both for the novice as well as for expert medicinal chemists and clinicians. The second volume of this ebook series covers topics including: -Clear Cell Renal Cell Carcinoma as a Model of Pathological Angiogenesis -Discovery and Development of Antiangiogenetic Drugs in Ovarian Cancer -Anti-Angiogenic Therapy and Cardiovascular Diseases … and more.

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323

Publisher

Bentham Science Publishers

Published Date

ISBN 10

1608058662

ISBN 13

9781608058662

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