Atsushi Doi's Books

Foundations of Systems Biology

Using Cell Illustrator and Pathway Databases

By: Masao Nagasaki,Ayumu Saito,Atsushi Doi,Hiroshi Matsuno,Satoru Miyano

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Foundations of Systems Biology

Using Cell Illustrator and Pathway Databases

By: Masao Nagasaki,Ayumu Saito,Atsushi Doi,Hiroshi Matsuno,Satoru Miyano

Today, as hundreds of genomes have been sequenced and thousands of proteins and more than ten thousand metabolites have been identi?ed, navigating safely through this wealth of information without getting completely lost has become crucial for research in, and teaching of, molecular biology. Consequently, a considerable number of tools have been developed and put on the market in the last two decades that describe the multitude of potential/putative interactions between genes, proteins, metabolites, and other biologically relevant compounds in terms of metabolic, genetic, signaling, and other networks, their aim being to support all sorts of explorations through bio-data bases currently called Systems Biology. As a result, navigating safely through this wealth of information-processing tools has become equally crucial for successful work in molecular biology. To help perform such navigation tasks successfully, this book starts by providing an extremely useful overview of existing tools for ?nding (or designing) and inv- tigating metabolic, genetic, signaling, and other network databases, addressing also user-relevant practical questions like • Is the database viewable through a web browser? • Is there a licensing fee? • What is the data type (metabolic, gene regulatory, signaling, etc. )? • Is the database developed/maintained by a curator or a computer? • Is there any software for editing pathways? • Is it possible to simulate the pathway? It then goes on to introduce a speci?c such tool, that is, the fabulous “Cell - lustrator 3. 0” tool developed by the authors.

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166

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Springer Science & Business Media

Published Date

ISBN 10

1848820232

ISBN 13

9781848820234

Periods of Quaternionic Shimura Varieties. I.

By: Atsushi Ichino,Kartik Prasanna

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Periods of Quaternionic Shimura Varieties. I.

By: Atsushi Ichino,Kartik Prasanna

This book formulates a new conjecture about quadratic periods of automorphic forms on quaternion algebras, which is an integral refinement of Shimura's algebraicity conjectures on these periods. It also provides a strategy to attack this conjecture by reformulating it in terms of integrality properties of the theta correspondence for quaternionic unitary groups. The methods and constructions of the book are expected to have applications to other problems related to periods, such as the Bloch-Beilinson conjecture about special values of $L$-functions and constructing geometric realizations of Langlands functoriality for automorphic forms on quaternion algebras.

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214

Publisher

American Mathematical Society

Published Date

ISBN 10

1470448947

ISBN 13

9781470448943

Speech Recognition Algorithms Using Weighted Finite-State Transducers

By: Takaaki Hori,Atsushi Nakamura

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Speech Recognition Algorithms Using Weighted Finite-State Transducers

By: Takaaki Hori,Atsushi Nakamura

This book introduces the theory, algorithms, and implementation techniques for efficient decoding in speech recognition mainly focusing on the Weighted Finite-State Transducer (WFST) approach. The decoding process for speech recognition is viewed as a search problem whose goal is to find a sequence of words that best matches an input speech signal. Since this process becomes computationally more expensive as the system vocabulary size increases, research has long been devoted to reducing the computational cost. Recently, the WFST approach has become an important state-of-the-art speech recognition technology, because it offers improved decoding speed with fewer recognition errors compared with conventional methods. However, it is not easy to understand all the algorithms used in this framework, and they are still in a black box for many people. In this book, we review the WFST approach and aim to provide comprehensive interpretations of WFST operations and decoding algorithms to help anyone who wants to understand, develop, and study WFST-based speech recognizers. We also mention recent advances in this framework and its applications to spoken language processing. Table of Contents: Introduction / Brief Overview of Speech Recognition / Introduction to Weighted Finite-State Transducers / Speech Recognition by Weighted Finite-State Transducers / Dynamic Decoders with On-the-fly WFST Operations / Summary and Perspective

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161

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Springer Nature

Published Date

ISBN 10

3031025628

ISBN 13

9783031025624

Turning the Right Corner

Ensuring Development Through a Low-Carbon Transport Sector

By: Andreas Kopp,Rachel I. Block

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Turning the Right Corner

Ensuring Development Through a Low-Carbon Transport Sector

By: Andreas Kopp,Rachel I. Block

Transport provides access to public services for the poor, opens up trade opportunities, and maximizes the benefits of urbanization: the mobility of people and goods drives development. So how can we protect the role of transport in times of scarcer fuels, costly and harmful carbon emissions, and the rising threat of extreme weather events? This is the central question that this book seeks to answer. Turning the Right Corner: Ensuring Development through a Low-Carbon Transport Sector finds that adopting new vehicle technologies and alternative fuels will not be enough to curb greenhouse gas emissions from transport: new patterns of mobility will also be needed. In developing countries where past infrastructure investments have not yet locked in particular transport modes, there is an opportunity to contain emissions by harnessing low-emission modes of transport. The book argues that the transition to low-carbon mobility is not only urgently needed if economies are to avoid becoming locked into high-carbon growth, but is also affordable. It outlines how countries can combine policies to reduce greenhouse gas emissions with broader sector reforms that generate new fiscal resources to finance the transition in addition to carbon financing and international assistance. Turning the Right Corner: Ensuring Development through a Low-Carbon Transport Sector will be of interest to policy makers, academics, and development practitioners with an interest in transport. It will help decision makers better understand how to contain the transport sector's contribution to climate change and protect transport infrastructure and services from severe weather events.

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182

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World Bank Publications

Published Date

ISBN 10

0821398350

ISBN 13

9780821398357

Humanoid Robots

Modeling and Control

By: Dragomir N. Nenchev,Atsushi Konno,Teppei Tsujita

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Humanoid Robots

Modeling and Control

By: Dragomir N. Nenchev,Atsushi Konno,Teppei Tsujita

Humanoid Robots: Modeling and Control provides systematic presentation of the models used in the analysis, design and control of humanoid robots. The book starts with a historical overview of the field, a summary of the current state of the art achievements and an outline of the related fields of research. It moves on to explain the theoretical foundations in terms of kinematic, kineto-static and dynamic relations. Further on, a detailed overview of biped balance control approaches is presented. Models and control algorithms for cooperative object manipulation with a multi-finger hand, a dual-arm and a multi-robot system are also discussed. One of the chapters is devoted to selected topics from the area of motion generation and control and their applications. The final chapter focuses on simulation environments, specifically on the step-by-step design of a simulator using the Matlab® environment and tools. This book will benefit readers with an advanced level of understanding of robotics, mechanics and control such as graduate students, academic and industrial researchers and professional engineers. Researchers in the related fields of multi-legged robots, biomechanics, physical therapy and physics-based computer animation of articulated figures can also benefit from the models and computational algorithms presented in the book. Provides a firm theoretical basis for modelling and control algorithm design Gives a systematic presentation of models and control algorithms Contains numerous implementation examples demonstrated with 43 video clips

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510

Publisher

Butterworth-Heinemann

Published Date

ISBN 10

0128045825

ISBN 13

9780128045824

Adelic Divisors on Arithmetic Varieties

By: Atsushi Moriwaki:

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Adelic Divisors on Arithmetic Varieties

By: Atsushi Moriwaki:

In this article, the author generalizes several fundamental results for arithmetic divisors, such as the continuity of the volume function, the generalized Hodge index theorem, Fujita's approximation theorem for arithmetic divisors, Zariski decompositions for arithmetic divisors on arithmetic surfaces and a special case of Dirichlet's unit theorem on arithmetic varieties, to the case of the adelic arithmetic divisors.

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134

Publisher

American Mathematical Soc.

Published Date

ISBN 10

1470419262

ISBN 13

9781470419264

Introduction to Quantum Technologies

By: Alto Osada,Rekishu Yamazaki,Atsushi Noguchi

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Introduction to Quantum Technologies

By: Alto Osada,Rekishu Yamazaki,Atsushi Noguchi

This book is a concise primer of quantum technology aiming at providing a comprehensive material of fundamentals to help beginners understand the common concepts and background theories to technologies for individual quantum systems. Further, it also describes how the concepts and theories are applied to technologies in various systems. This book consists of three parts. The first part looks back over basics of quantum mechanics necessary for the main content, including quantum state and operators, time evolution and perturbation theory. The second part explains in detail key components indispensable to follow quantum technologies: two-level systems, harmonic oscillator and cavity quantum electrodynamics and resonators. In the third part, the physical quantum systems are treated in a more abstract way by introducing quantum logic gates, quantum measurement and quantum error correction. Technical supplements are included in Appendices. The well-compiled topics and concise presentation feature the book as a supplemental primer in the courses of quantum technologies including quantum computing, quantum communication, quantum sensing and quantum simulation.

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298

Publisher

Springer Nature

Published Date

ISBN 10

9811946418

ISBN 13

9789811946417

The World of Nano-Biomechanics

By: Atsushi Ikai

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The World of Nano-Biomechanics

By: Atsushi Ikai

The World of Nano-Biomechanics, Second Edition, focuses on the remarkable progress in the application of force spectroscopy to molecular and cellular biology that has occurred since the book's first edition in 2008. The initial excitement of seeing and touching a single molecule of protein/DNA is now culminating in the development of various ways to manipulate molecules and cells almost at our fingertips, enabling live cell operations. Topics include the development of molecular biosensors, mechanical diagnosis, cellular-level wound healing, and a look into the advances that have been made in our understanding of the significance of mechanical rigidity/flexibility of protein/DNA structure for the manifestation of biological activities. The book begins with a summary of the results of basic mechanics to help readers who are unfamiliar with engineering mechanics. Then, representative results obtained on biological macromolecules and structures, such as proteins, DNA, RNA, polysaccharides, lipid membranes, subcellular organelles, and live cells are discussed. New to this second edition are recent developments in three important applications, i.e., advanced AFM-data analysis, high-resolution mechanical biosensing, and the use of cell mechanics for medical diagnosis. - Explains the basic physical concepts and mathematics of elementary mechanics needed to understand and perform experimental work on small-scale biological samples - Presents recent developments of force-based biosensing - Includes novel applications of nano-biomechanics to the medical field

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342

Publisher

Elsevier

Published Date

ISBN 10

0444636870

ISBN 13

9780444636874

Vesiculation and Crystallization of Magma

Fundamentals of the Volcanic Eruption Process

By: Atsushi Toramaru

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Vesiculation and Crystallization of Magma

Fundamentals of the Volcanic Eruption Process

By: Atsushi Toramaru

This book comprehensively illustrates the elemental processes of vesiculation and crystallization recorded in volcanic products on the basis of the equilibrium and non-equilibrium theories. The book describes the derivation of equations and the basic physics behind them in detail. This textbook is fundamental in preparing for future volcanic hazards. The target readers are graduate students and researchers, but Parts I and IV are written to be understandable by undergraduate students as well, to inspire them to enter this field.

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449

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Springer Nature

Published Date

ISBN 10

9811642095

ISBN 13

9789811642098

Reinforcement of Rubber

Visualization of Nanofiller and the Reinforcing Mechanism

By: Shinzo Kohjiya,Atsushi Kato,Yuko Ikeda

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Reinforcement of Rubber

Visualization of Nanofiller and the Reinforcing Mechanism

By: Shinzo Kohjiya,Atsushi Kato,Yuko Ikeda

This book presents the most recent description of rubber reinforcement, focusing on the network-like structure formation of nanofiller in the rubber matrix under the presence of bound rubber. The resultant filler network is visualized by electron tomography applied to rubber. In the case of natural rubber, the self-reinforcement effect is uniquely functioning, and new template crystallization is suggested. Here, the crystallites are also believed to arrange themselves in a network-like manner. These results are of great use, particularly for engineers, in designing rubber reinforcement.

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193

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Springer Nature

Published Date

ISBN 10

9811537895

ISBN 13

9789811537899

Comparison of Relatively Unipotent Log de Rham Fundamental Groups

By: Bruno Chiarellotto,Valentina Di Proietto,Atsushi Shiho

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Comparison of Relatively Unipotent Log de Rham Fundamental Groups

By: Bruno Chiarellotto,Valentina Di Proietto,Atsushi Shiho

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124

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American Mathematical Society

Published Date

ISBN 10

1470467062

ISBN 13

9781470467067

The Social Lives of Study Abroad

Understanding Second Language Learners' Experiences through Social Network Analysis and Conversation Analysis

By: Atsushi Hasegawa

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The Social Lives of Study Abroad

Understanding Second Language Learners' Experiences through Social Network Analysis and Conversation Analysis

By: Atsushi Hasegawa

This volume presents an innovative approach to understanding the language socialization process of second language learners in study abroad programs, focusing on the case of study abroad programs in Japan. Study abroad experiences are so diverse that both macro and micro viewpoints are needed to capture such complexity. This book looks for a way forward by adopting a novel approach which integrates social network analysis and conversation nalysis and allows for a fuller, more nuanced understanding of varying experiences of study abroad participants. Chapters draw on data from a wide range of sources, including participant observation, semi-structured interviews, social network surveys, and audio and visual recordings, to demonstrate the ways in which broader social forces, environmental factors, and individuals’ dispositions interact in myriad social contexts within the study abroad experience. Taken together, the volume offers readers a comprehensive portrait of social processes in study abroad programs and their implications for language development, making this key reading for students and scholars in second language acquisition, pragmatics, and applied linguistics.

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224

Publisher

Routledge

Published Date

ISBN 10

0429013426

ISBN 13

9780429013423

The 3D Stereotaxic Brain Atlas of the Degu

With MRI and Histology Digital Model with a Freely Rotatable Viewer

By: Noriko Kumazawa-Manita,Tsutomu Hashikawa,Atsushi Iriki

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The 3D Stereotaxic Brain Atlas of the Degu

With MRI and Histology Digital Model with a Freely Rotatable Viewer

By: Noriko Kumazawa-Manita,Tsutomu Hashikawa,Atsushi Iriki

This book is the first digital atlas of the degu brain with microscopic features simultaneously in Nissl sections and magnetic resonance imaging (MRI). As an experimental animal model, the degu contributes to a variety of medical research fields in diabetes, hyperglycemia, pancreatic function, and adaptation to high altitude, among others. Recently the degu has gained increasing importance in the field of neuroscience, particularly in studies evaluating the relationship between sociality and cognitive brain functions, and in studies pertaining to the evolutional aspects of the acquisition of tool-use abilities. Furthermore, aging-related brain dysfunction in humans can be studied using this animal model in addition to mammals with much longer lifespans. This brain atlas is constructed to provide histological and volume-rendered information simultaneously, fitting with any spatial coordination in brain positioning. It can be a useful guide to degus as well as to other rodents for studies of brain structures conducted using MRI or other contemporary examination methods with volume-rendering functions.

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149

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Springer

Published Date

ISBN 10

4431566155

ISBN 13

9784431566151

Spatial Analysis of Liberia's Transport Connectivity and Potential Growth

By: Atsushi Iimi,Kulwinder Rao

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Spatial Analysis of Liberia's Transport Connectivity and Potential Growth

By: Atsushi Iimi,Kulwinder Rao

Liberia has been influenced by the Ebola crisis since 2014, but the economy is now recovering quickly. Still, significant challenges lie ahead. Agriculture, an important sector that employs approximately half of the labor force, still has a weak growth trajectory. Many rural people are not well connected to markets and live below the poverty line. To use limited resources effectively, strategic planning and prioritization of public investment are essential. Particularly, the Ebola crisis revealed the vulnerability of the country's transport connectivity and health systems. This book analyzes the country's transport connectivity, identifying the existing bottlenecks and possible economic potentials. By taking advantage of the country's first-ever georeferenced road network data, the analysis casts light on various aspects of connectivity, such as rural accessibility, market access, access to port and health facilities and multimodal connectivity, including cabotage. It is shown that transport connectivity is crucial to increasing agricultural production, stimulating agglomeration economies, and supporting people's access to health care services. Significant resources are likely to be required to meet the existing gap. The book estimates the financial needs by development objective and discusses important policy issues, including the possibility of public-private partnerships to finance transport infrastructure.

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133

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World Bank Publications

Published Date

ISBN 10

1464812861

ISBN 13

9781464812866

Jump SDEs and the Study of Their Densities

A Self-Study Book

By: Arturo Kohatsu-Higa,Atsushi Takeuchi

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Jump SDEs and the Study of Their Densities

A Self-Study Book

By: Arturo Kohatsu-Higa,Atsushi Takeuchi

The present book deals with a streamlined presentation of Lévy processes and their densities. It is directed at advanced undergraduates who have already completed a basic probability course. Poisson random variables, exponential random variables, and the introduction of Poisson processes are presented first, followed by the introduction of Poisson random measures in a simple case. With these tools the reader proceeds gradually to compound Poisson processes, finite variation Lévy processes and finally one-dimensional stable cases. This step-by-step progression guides the reader into the construction and study of the properties of general Lévy processes with no Brownian component. In particular, in each case the corresponding Poisson random measure, the corresponding stochastic integral, and the corresponding stochastic differential equations (SDEs) are provided. The second part of the book introduces the tools of the integration by parts formula for jump processes in basic settings and first gradually provides the integration by parts formula in finite-dimensional spaces and gives a formula in infinite dimensions. These are then applied to stochastic differential equations in order to determine the existence and some properties of their densities. As examples, instances of the calculations of the Greeks in financial models with jumps are shown. The final chapter is devoted to the Boltzmann equation.

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363

Publisher

Springer

Published Date

ISBN 10

9813297417

ISBN 13

9789813297418

Venus Versus Virus Vol. 3

By: Atsushi Suzumi

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Venus Versus Virus Vol. 3

By: Atsushi Suzumi

They've been observing from the shadows, but no more! Sonoka's minions finally reveal their presence, and they've set their sights on ripping out the hearts of every person with the power of Vision. And that means only one thing--it's up to Lucia, Sumire, and Nahashi to track down each and every client Venus Vangard has ever defended before it's too late!

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186

Publisher

Seven Seas Entertainment

Published Date

ISBN 10

164505084X

ISBN 13

9781645050841

Will It Be the World or Her? 6

By: Atsushi Uchiyama

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Will It Be the World or Her? 6

By: Atsushi Uchiyama

Does Ayumi feel the same?! But Koki knows that if he confesses, it’s lights out of for the world. Jindo’s sexy traps really kick it up a notch! But if he gives in to temptation, it’ll be a bloodbath. And then there’s Tenshi’s plan to quickly approach Ayumi because she is after Ayumi’s powers. Koki then finds himself in a situation he can no longer flee from. He must choose between Ayumi, Jindo, or Tenshi in front of the entire school! “The time has come, Nakagawa!! Who will it be?!” Does he want the world, the girl, or heaven? The choice he makes will seal the fate of everyone present. The supremely extravagant, ultimate choice romcom finally reaches its climax!!

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193

Publisher

Kodansha America LLC

Published Date

ISBN 10

1636991513

ISBN 13

9781636991511

Spectroscopy of Mott Insulators and Correlated Metals

Proceedings of the 17th Taniguchi Symposium Kashikojima, Japan, October 24–28, 1994

By: Atsushi Fujimori,Yoshinori Tokura

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Spectroscopy of Mott Insulators and Correlated Metals

Proceedings of the 17th Taniguchi Symposium Kashikojima, Japan, October 24–28, 1994

By: Atsushi Fujimori,Yoshinori Tokura

Extensive studies of high-Tc cuprate superconductors have stimualted investigations into various transition-metal oxides. Mott transitions in particular provide fascinating problems and new concepts in condensed matter physics. This book is a collection of overviews by well-known, active researchers in this field. It deals with the latest developments, with particular emphasis on the theoretical, spectroscopic, and transport aspects.

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272

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3642578349

ISBN 13

9783642578342

Recent advances in Pancreatology

By: Atsushi Masamune

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Recent advances in Pancreatology

By: Atsushi Masamune

Pancreatic diseases include intractable ones including acute and chronic pancreatitis, and pancreatic cancer. In recent years, great advances have been made in the field of pancreatology, including the pathogenesis, diagnostic modalities, and development of novel therapeutic interventions. It has been established that pancreatic stellate cells play a pivotal role in the development of pancreatic fibrosis in chronic pancreatitis as well as in pancreatic cancer known as desmoplastic reaction. Although it might be still controversial, accumulating evidence has shown that interaction between pancreatic stellate cells-cancer cells contribute to the progression of pancreatic cancer through the increased proliferation and migration, and production of cytokines and extracellular matrix components. In addition, pancreatic stellate cells lead to the resistance to chemotherapy and radiation therapy. Pancreatic stellate cells attract the researchers as a novel therapeutic target of pancreatic cancer. Genetic studies have shown that mutations in the trypsin-related genes such as cationic trypsinogen (PRSS1) gene and the serine protease inhibitor, Kazal type 1 (SPINK1) gene are associated with pancreatitis. In general, each of these factors appears to limit trypsin activation or enhance inactivation, and is believed to increase intrapancreatic trypsin activity and predispose to pancreatitis when the gene is mutated. These results have supported a concept that pancreatic protease/anti-protease plays pivotal roles in the pathogenesis of pancreatitis. In addition, genetic studies focusing on phenotypic variances would provide us with important information how genetic variants would affect the phenotypic variances. Autophagy is an intracellular bulk degradation system in which cytoplasmic components are directed to the lysosome/vacuole by a membrane-mediated process. Recent studies have highlighted a role of autophagy in acute pancreatitis. Using a conditional knockout mouse that lacks the autophagy-related (Atg) gene Atg5 in the pancreatic acinar cells, autophagy exerts a detrimental effect in pancreatic acinar cells by activation of trypsinogen to trypsin. A theory in which autophagy accelerates trypsinogen activation by lysosomal hydrolases under acidic conditions, thus triggering acute pancreatitis in its early stage. The epithelial-mesenchymal transition is a developmental process that allows a polarized epithelial cell to undergo multiple biochemical changes that enable it to assume a mesenchymal phenotype. The phenotype associated with epithelial-mesenchymal transition includes enhanced migratory capacity, invasiveness, elevated resistance to apoptosis, and greatly increased production of extracellular matrix components. In addition to its role in development, tissue regeneration, and fibrosis, epithelial-mesenchymal transition is now considered as a critical process in cancer progression. Induction of epithelial-mesenchymal transition in cancer cells results in the acquisition of invasive and metastatic properties. Epithelial-mesenchymal transition could be an important mechanism in the progression of pancreatic cancer and its poor prognosis. Autoimmune pancreatitis is a unique form of pancreatitis in which autoimmune mechanisms are suspected to be involved in the pathogenesis. There is accumulating study to deal with this new disease concept. In addition to these topics, we have selected several topics in pancreatology, focusing on recent studies increasingly deepening our knowledge in both basic and clinical researches.

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