An accessible guide that introduces students in all areas of life sciences to bioinformatics Basic Applied Bioinformatics provides a practical guidance in bioinformatics and helps students to optimize parameters for data analysis and then to draw accurate conclusions from the results. In addition to parameter optimization, the text will also familiarize students with relevant terminology. Basic Applied Bioinformatics is written as an accessible guide for graduate students studying bioinformatics, biotechnology, and other related sub-disciplines of the life sciences. This accessible text outlines the basics of bioinformatics, including pertinent information such as downloading molecular sequences (nucleotide and protein) from databases; BLAST analyses; primer designing and its quality checking, multiple sequence alignment (global and local using freely available software); phylogenetic tree construction (using UPGMA, NJ, MP, ME, FM algorithm and MEGA7 suite), prediction of protein structures and genome annotation, RNASeq data analyses and identification of differentially expressed genes and similar advanced bioinformatics analyses. The authors Chandra Sekhar Mukhopadhyay, Ratan Kumar Choudhary, and Mir Asif Iquebal are noted experts in the field and have come together to provide an updated information on bioinformatics. Salient features of this book includes: Accessible and updated information on bioinformatics tools A practical step-by-step approach to molecular-data analyses Information pertinent to study a variety of disciplines including biotechnology, zoology, bioinformatics and other related fields Worked examples, glossary terms, problems and solutions Basic Applied Bioinformatics gives students studying bioinformatics, agricultural biotechnology, animal biotechnology, medical biotechnology, microbial biotechnology, and zoology an updated introduction to the growing field of bioinformatics.
Each issue of Orthopedic Clinics offers clinical review articles on the most cutting edge technologies, techniques, and more in the field. Major topic areas include: adult reconstruction, upper extremity, pediatrics, trauma, oncology, hand, foot and ankle, and sports medicine.
Globalisation stands as an indispensable lens through which to analyse current cultural, political, and social transformations. This prevailing paradigm, acknowledged by its advocates and critics, profoundly shapes our environment. Within this global landscape, Islam's position is noteworthy—often perceived as rejecting globalisation and its secular underpinnings. This book offers a perspective of the global resurgence of religion in general and the revival of Islam in particular as crucial features of globalisation. Furthermore, the book deeply explores how Islamist groups strategically challenge religious authority, utilising social media and the internet to reshape their spheres of influence. By exploring these dynamics, the book aims to provide comprehensive insights into the interplay between Islamist strategies, digital platforms, and religious institutions within our interconnected world.
A stunning history of Pakistan’s cultural and intellectual capital, from one of the preeminent scholars of South Asia The city of Lahore was more than one thousand years old when it went through a violent schism. As the South Asian subcontinent was partitioned in 1947 to gain freedom from Britain’s colonial hold, and the Islamic Republic of Pakistan was formed, the city’s large Hindu and Sikh populations were pushed toward India, and an even larger Muslim refugee population settled in the city. This was just the latest in a long history of the city’s making and unmaking. Over the centuries, the city has kept a firm grip on the imagination of travelers, poets, writers, and artists. More recently, it has been journalists who have been drawn to the city as a focal point for a nation that continues to grab international headlines. For this book, acclaimed historian Manan Ahmed Asif brings to life a diverse and vibrant world by walking the city again and again over the course of many years. Along the way he joins Sufi study circles and architects doing restoration in the medieval parts of Lahore and speaks with a broad range of storytellers and historians. To this Asif juxtaposes deep analysis of the city’s centuries-old literary culture, noting how it reverberates among the people of Lahore today. To understand modern Pakistan requires understanding its cultural capital, and Disrupted City uses Lahore’s cosmopolitan past and its fractured present to provide a critical lens to challenge the grand narratives of the Pakistani nation-state and its national project of writing history.
A field-changing history explains how the subcontinent lost its political identity as the home of all religions and emerged as India, the land of the Hindus. Did South Asia have a shared regional identity prior to the arrival of Europeans in the late fifteenth century? This is a subject of heated debate in scholarly circles and contemporary political discourse. Manan Ahmed Asif argues that Pakistan, Bangladesh, and the Republic of India share a common political ancestry: they are all part of a region whose people understand themselves as Hindustani. Asif describes the idea of Hindustan, as reflected in the work of native historians from roughly 1000 CE to 1900 CE, and how that idea went missing. This makes for a radical interpretation of how India came to its contemporary political identity. Asif argues that a European understanding of India as Hindu has replaced an earlier, native understanding of India as Hindustan, a home for all faiths. Turning to the subcontinent’s medieval past, Asif uncovers a rich network of historians of Hindustan who imagined, studied, and shaped their kings, cities, and societies. Asif closely examines the most complete idea of Hindustan, elaborated by the early seventeenth century Deccan historian Firishta. His monumental work, Tarikh-i Firishta, became a major source for European philosophers and historians, such as Voltaire, Kant, Hegel, and Gibbon during the eighteenth and nineteenth centuries. Yet Firishta’s notions of Hindustan were lost and replaced by a different idea of India that we inhabit today. The Loss of Hindustan reveals the intellectual pathways that dispensed with multicultural Hindustan and created a religiously partitioned world of today.
The extent of urban air pollution in Pakistan—South Asia's most urbanized country—is among the world’s most severe, significantly damaging human health, quality of life, and the economy and environment of Pakistan. The harm from Pakistan's urban air pollution is among the highest in South Asia, exceeding several high-profile causes of mortality and morbidity in Pakistan. Improved air quality management (AQM) in Pakistan can have notable economic and health benefits. For example, the estimated health benefits per dollar spent on cleaner diesel are approximately US $1–1.5 for light-duty diesel vehicles and US $1.5–2.4 for large buses and trucks. This report advocates that Pakistan allocate resources to AQM, because its air quality is severely affecting millions of Pakistanis, and because experiences around the world indicate that interventions can significantly improve air quality. This report details a broad spectrum of research on Pakistan’s AQM challenges, and identifies a comprehensive set of steps to improve air quality. The research presented here underpins the conclusions that addressing Pakistan's urban air pollution requires coordinated interventions to strengthen AQM, build agencies' institutional capacity, bolster AQM's legal and regulatory framework, implement policy reforms and investments, and fill knowledge gaps. However, Pakistan's policy makers face major obstacles, including limited financial, human, and technical resources, and can pursue only a few AQM interventions at the same time. In the short term, Pakistan's AQM should give highest priority to reducing pollutants linked to high morbidity and mortality: PM2.5 (and precursors like SOx and NOx) from mobile sources. A second-level short-term priority could be PM2.5, SOx, and emissions of toxic metals from stationary sources. An important medium-term priority should be mass transportation in major cities, controlling traffic, and restricting private cars during high-pollution episodes. A long-term priority could be taxing hydrocarbons, based on their contribution to greenhouse gases.
Cover -- Title -- Copyright -- Dedication -- Contents -- List of Illustrations -- Note on Transliteration and Translation -- Introduction -- Chapter 1. Frontier with the House of Gold -- Chapter 2. A Foundation for History -- Chapter 3. Dear Son, What Is the Matter with You? -- Chapter 4. A Demon with Ruby Eyes -- Chapter 5. The Half Smile -- Chapter 6. A Conquest of Pasts -- Conclusion -- Notes -- Works Cited -- Acknowledgments -- Index
Unlike other fields of medicine, with their occasional “oddities,” the Intensive Care Unit sets the stage for a steady stream of unique medical challenges and patients who don’t fit a standard profile. Fainting Pulse is a compelling compilation of stories based on these real-life cases—and told by the doctor who lived them. While some patients come and go from critical care quickly and uneventfully, others leave a permanent mark on their caregiver’s souls. Among the dramatic stabbings, shootings, and freak car crashes, there are stories of exceptional patients and exceptional circumstances. Fainting Pulse shares some of these stories—from a woman struck by lightning to a man whose toothpick habit is nearly fatal; from swine flu to maggot therapy—with compassion, respect, and a healthy dose of humor.
A 19-year-old, young man comes to the capital of India from a violence-ravaged district of Bihar, thinking that in Delhi, the rules of the game will be different, climbing up will be easy, opportunities will be, too many, and the journey will be exciting and pleasant. He aimed high and thought there was nothing that he could not achieve. It was just a matter of time before success and medals would be at his feet. As he steps into the capital, he realises that the path is tough. He thinks hard work, studying and courage are enough to take on the world. Constant efforts to improve oneself, and hunger for recognition will change everything in his life. It would get him money, status, fame, and everything that he aspired for. But he has no resources, no precedent, no money in his pocket, average talent, a sick body, and alluring distractions. Difficulties, failures, deprivation and despair weaken the flame of his ambition. However, he stands in the arena and continues with his efforts. He extracts maximum return from every passing moment, enriches himself with the best books, decodes the secrets of success, and finally one day he wins. The character Hameed Akhtar gives an account of this difficult and painful journey in the first person.
Contributions by Surhid Gautam and Lit-Mian Chan. This book presents a state-of-the art review of vehicle emission standards and regulations and provides a synthesis of worldwide experience with vehicle emission control technologies and their applications in both industrial and developing countries. Topics covered include: * The two principal international systems of vehicle emission standards: those of North America and Europe * Test procedures used to verify compliance with emissions standards and to estimate actual emissions * Engine and aftertreatment technologies that have been developed to enable new vehicles to comply with emission standards, as well as the cost and other impacts of these technologies * An evaluation of measures for controlling emissions from in-use vehicles * The role of fuels in reducing vehicle emissions, the benefits that could be gained by reformulating conventional gasoline and diesel fuels, the potential benefits of alternative cleaner fuels, and the prospects for using hydrogen and electric power to run motor vehicles with ultra-low or zero emissions. This book is the first in a series of publications on vehicle-related pollution and control measures prepared by the World Bank in collaboration with the United Nations Environment Programme to underpin the Bank's overall objective of promoting transport that is environmentally sustainable and least damaging to human health and welfare.
The second edition with the addition of permanent values to eradicate crime from the society has made it more thought provoking at the face of sectarianism, extremism, intolerance, terrorism, and corruption: it is revolutionary, opening new vistas and bold horizons of intellectual endeavors. The book is thus a unique attempt at the rediscovery of maintaining Law & Order for permanent values: scholarly written and exquisitely presented.
This book provides new contributions to the theory of inequalities for integral and sum, and includes four chapters. In the first chapter, linear inequalities via interpolation polynomials and green functions are discussed. New results related to Popoviciu type linear inequalities via extension of the Montgomery identity, the Taylor formula, Abel-Gontscharoff's interpolation polynomials, Hermite interpolation polynomials and the Fink identity with Green’s functions, are presented. The second chapter is dedicated to Ostrowski’s inequality and results with applications to numerical integration and probability theory. The third chapter deals with results involving functions with nondecreasing increments. Real life applications are discussed, as well as and connection of functions with nondecreasing increments together with many important concepts including arithmetic integral mean, wright convex functions, convex functions, nabla-convex functions, Jensen m-convex functions, m-convex functions, m-nabla-convex functions, k-monotonic functions, absolutely monotonic functions, completely monotonic functions, Laplace transform and exponentially convex functions, by using the finite difference operator of order m. The fourth chapter is mainly based on Popoviciu and Cebysev-Popoviciu type identities and inequalities. In this last chapter, the authors present results by using delta and nabla operators of higher order.
Although Asif Zaidi is a banker and a business leadership advisor by profession, he is fundamentally a thinker of broad understanding and interests. In The Stuff of Life, he offers an anthology of thoughts on diverse subjects, attempting to see the problems of life in the light of human reasoning. Asif Zaidi is endlessly curious, and leaves no big question untouched. While turning his gaze from one intellectual pursuit to the next, in this collection of essays he addresses nature, evolution, religion, literature, psychology, and scientists, sages, prophets, philosophers, thinkers, and poets who have, down the ages, contributed to human development, making life meaningful. From the personal to the societal to the universal, he turns his spirit of inquiry to a wide swathe of topics: the love of learning: mans search for meaning: faith, tradition, and rationality: and the moral dimension of existence. Simple and direct, The Stuff of Life articulates a viewpoint grounded in a rational approach to life and this world.
Each issue of Orthopedic Clinics offers clinical review articles on the most cutting edge technologies, techniques, and more in the field. Major topic areas include: adult reconstruction, upper extremity, pediatrics, trauma, oncology, hand, foot & ankle, and sports medicine.
This two volume set is a complete guide to the surgical management of fractures and complications. Volume one discusses the upper extremity and spine and Volume two examines the pelvis and lower extremity. Each chapter discusses a different type of fracture, providing a step by step guide through history, clinical presentation, diagnostic testing, imaging, treatment and complications. Written by a recognised US author and editor team, this comprehensive manual features 2000 colour illustrations, including numerous fluoroscopic images, as well as a selection of case studies. Key Features Two volume set providing complete guidance to surgical management of fractures and complications Numerous different types of fracture discussed with practical, procedural approach Authored by US specialists
Good writings defy time and immediate surroundings to sustain their appeal. The entrancing aura of a well-knit article or story is lasting. Surely, Hardy's rustic Tess or Jude couldn't be out of sync in the year 2020 for technology savvy readers obsessed with Instagram, Twitter, Facebook and accompanying high-tech spinoffs. Without being extravagant with words, one may say the same is true of Dr. Asif Javed's writings. Insightful and instructive, they are studded with revealing facts that are well documented to testify to the innate truth. The gifted writer tells us of the life and time of the Bronte Sisters, Ibn Batuta, Leo Tolstoy, Rudyard Kipling, Nawab of Kalabagh, Zulfiqar Ali Bhutto et al. In more ways than one, the articles remind the reader of Dale Carnegie's 'Little Known Facts about Well-Known People'. Today, he is one of the most fluent and readable purveyors of the English language in the Pakistani American community. His writings have ranged from Punjab politics to port-partition Indian cinema, to English literature, to the Tsarist wars in Dagestan. All the time, he manages to convey, seemingly dense subjects in a seamless flowing style, making his writings a treat to read.
In Tales of Two Cities, two eminent journalists - Kuldip Nayar and Asif Noorani - give their personal accounts of the Partition of India, the killings and massive migrations which it provoked and their subsequent impact on Indo-Pakistan relations. As a young law graduate, Kuldip Nayar witnessed at first hand the collapse of trust between communities in Sialkot and was forced to migrate with his family to Delhi across the blood-stained plains of Punjab. He vividly describes his own perilous journey and his first job as a young journalist in an Urdu newspaper reporting on Gandhi's assassination. Asif Noorani, while still a schoolboy in Bombay, set off with his family by steamer across the Arabian Sea for the promised land of Pakistan, ultimately settling in Karachi. He gives his own compelling account of the difficulties faced by the new arrivals and the slow emergence of today's megacity with its dominant Mohajir culture. Both authors write with authority about their ancestral homes and their adopted cities, which have played so large a role in bilateral relations. This is a book about a trauma which transformed the subcontinent and still exerts a powerful influence today. These are personal narratives bringing to life a lost world of harmonious relations which each author in his own way is still to recreate.
This book is concerned with the development of design techniques for controlling motion of mechanical systems which are employed to execute certain tasks acting collaboratively. The book introduces unified control design procedure for functionally related systems. The controllers for many different tasks in motion control can be successfully designed by applying the proposed simple procedure. The book gives an overview of the control methods appearing in the motion control area and the detailed design procedures for the class of systems that are required to execute certain task together. Tasks can generally be divided in their components, denoted as functions in the book. It is shown how dynamics of those tasks can be described. Based on the presented description, several control methods were discussed. Applicability of the introduced control design approach was demonstrated in subsequent chapters for various tasks.
From Revolutions to Revival: A Journey Through Modernity" by Asif Ahmed Srabon Explore the transformative journey of modernity in this captivating book by Asif Ahmed Srabon. Delve into revolutions and revival, as Srabon unravels the forces shaping our world. A must-read for those seeking a deeper understanding of our past and present.
Each issue of Orthopedic Clinics offers clinical review articles on the most cutting edge technologies, techniques, and more in the field. Major topic areas include: adult reconstruction, upper extremity, pediatrics, trauma, oncology, hand, foot and ankle.
A strong yet balanced tone of emotional fervor rings in Asif Siddiqis plea for the political and economic re-union of India and Pakistan, which gives fresh relevance and urgency to this long -standing theme of postcolonial South Asian politics. Was Pakistan ever the pan-Muslim state it claimed to be, necessary for staving off kafir domination? This is one of the key questions about the birth of the state that the author asks. He demolishes the very concept of any hard-and-fast Hindu-Muslim divide by highlighting the psychic factors underlying the creation of Bangladesh. These psychic factors, he points out, originate from perceptions and behavior far older than those based on religion. They stem from primitive, racist reactions to chance externals like skin color and body build. To the West Pakistani state and establishments, their coreligionists to the East were kaalay haramisblack bastards first and co-religionists never. With this kind of primitivism underwriting the birth of the new state, is it any wonder that it never did take off in the direction of freedom and prosperity? Diverse, mutually confronting groups in any part of the world do not yet entertain ideas of mass migration elsewhere. When they do so, as in 1947, it is solely from the pushes and pulls of political parties. Sentiments of home and hearth are more deep-rooted than political exhortations for cutting cord and feeling. When the latter prevail, bloodletting and killer instincts gain unfettered play. Even after these fade, feelings of homesickness and homelessness, of uprootedness, roost in the migrants inner regions of being. The words and voice of born humanists like Ghalib keep playing in his ears, giving him a sense of completion that other realities do not, but it cannot stop him from reaching for it. Remorse and hope undying coexist. The Muslims are not separate from the Hindus nor vice versa. Different, yes, but not separate, not two. And they will eventually travel back to their basic oneness from the sheer compulsions of global forces at work today. These views, however debatable, are worth hearing for they concern almost a quarter of the human race. - by Raji Narasimhan
Bioinformatics allows researchers to answer biological questions with advanced computational methods which involves the application of statistics and mathematical modeling. Structural bioinformatics enables the prediction and analysis of 3D structures of macromolecules while Computer Aided Drug Designing (CADD) assists scientists to design effective active molecules against diseases. However, the concepts in structural bioinformatics and CADD can be complex to understand for students and educated laymen. This quick guideline is intended as a basic manual for beginner students and instructors involved in bioinformatics and computational chemistry courses. Readers will learn the basics of structural bioinformatics, primary and secondary analysis and prediction, structural visualization, structural analysis and molecular docking. Therefore, the book is a useful handbook for aspiring scholars who wish to learn the basic concepts in computational analysis of biomolecules.
A complete guide to every aspect of interventional nephrology ... for students, residents, fellows, and clinicians ... [it] examines all relevant aspects of interventional nephrology, from the history of nephrology to the principles governing the latest vascular access techniques."--Provided by publisher
An accessible guide that introduces students in all areas of life sciences to bioinformatics Basic Applied Bioinformatics provides a practical guidance in bioinformatics and helps students to optimize parameters for data analysis and then to draw accurate conclusions from the results. In addition to parameter optimization, the text will also familiarize students with relevant terminology. Basic Applied Bioinformatics is written as an accessible guide for graduate students studying bioinformatics, biotechnology, and other related sub-disciplines of the life sciences. This accessible text outlines the basics of bioinformatics, including pertinent information such as downloading molecular sequences (nucleotide and protein) from databases; BLAST analyses; primer designing and its quality checking, multiple sequence alignment (global and local using freely available software); phylogenetic tree construction (using UPGMA, NJ, MP, ME, FM algorithm and MEGA7 suite), prediction of protein structures and genome annotation, RNASeq data analyses and identification of differentially expressed genes and similar advanced bioinformatics analyses. The authors Chandra Sekhar Mukhopadhyay, Ratan Kumar Choudhary, and Mir Asif Iquebal are noted experts in the field and have come together to provide an updated information on bioinformatics. Salient features of this book includes: Accessible and updated information on bioinformatics tools A practical step-by-step approach to molecular-data analyses Information pertinent to study a variety of disciplines including biotechnology, zoology, bioinformatics and other related fields Worked examples, glossary terms, problems and solutions Basic Applied Bioinformatics gives students studying bioinformatics, agricultural biotechnology, animal biotechnology, medical biotechnology, microbial biotechnology, and zoology an updated introduction to the growing field of bioinformatics.
Bioinformatics allows researchers to answer biological questions with advanced computational methods which involves the application of statistics and mathematical modeling. Structural bioinformatics enables the prediction and analysis of 3D structures of macromolecules while Computer Aided Drug Designing (CADD) assists scientists to design effective active molecules against diseases. However, the concepts in structural bioinformatics and CADD can be complex to understand for students and educated laymen. This quick guideline is intended as a basic manual for beginner students and instructors involved in bioinformatics and computational chemistry courses. Readers will learn the basics of structural bioinformatics, primary and secondary analysis and prediction, structural visualization, structural analysis and molecular docking. Therefore, the book is a useful handbook for aspiring scholars who wish to learn the basic concepts in computational analysis of biomolecules.
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