Thorough Understanding Of Inorganic Chemistry And Also Inorganic Analysis Are Best Achieved Through Rigourous Processes Of Problems And Exercises. This Provides The Students With Clear Concepts Of The Subject Matter In Their Proper Perspective. This New Edition, Thoroughly Recast And Updated, Will Equip The Students With Modern Concepts Of Inorganic Chemistry As Well As Inorganic Analysis, So That They Can Face The Challenges Of The New Century In Shaping Their Future Career In The Best Possible Manner.This Book, In Combination With Its Parent Volume: A Textbook Of Inorganic Chemistry3⁄4A.K. De, 9Th Ed. (2003), New Age International Is Destined To Satisfy The Challenging Requirements Of B.Sc. Hons./Major Students Of Indian Universities And Also Net (Csir-Ugc), Gate (Iits) And Slet Examinees.
This book is the first of its kind offering a materialistic semiotic analysis of a non-Western theatre culture: Bengali group theatre. Arnab Banerji fills two lacunas in contemporary theatre scholarship. First, the materialist semiotic approach to studying a non-Western theatre event allows Banerji to critically examine the material conditions in which theatre is created and seen outside the Euro-American context. And second, by shifting the critical lens onto a contemporary urban theatre phenomenon from India, the book attempts to even out the scholastic imbalance in Indian theatre scholarship which has largely focused on folk and classical traditions. The book shows a refreshing new perspective toward a theatre culture that frequently escapes the critical lens in spite of being one of the largest urban theatre cultures in the world. Theatre events are a sum total of the conditions in which they are built and the conditions in which they are viewed. Studying the event separate from its materialistic beginnings and semiotic effects allow only a partial insight into the performance phenomenon. The materialist semiotic critical framework of this book locates the Bengali group theatre within its performative context and offers a heretofore unexplored insight into this vibrant theatre culture.
This is the first volume to focus specifically on Rabindranath Tagore’s dramatic literature, visiting translations and adaptations of Tagore’s drama, and cross-cultural encounters in his works. As Asia’s first Nobel Laureate, Tagore’s highly original plays occupy a central position in the Indian theatrescape. Tagore experimented with dance, music, dance drama, and plays, exploring concepts of environment, education, gender and women, postcolonial encounters, romantic idealism, and universality. Tagore’s drama plays a generous host to experimentations with new performance modes, like the writing and staging of an all-women play on stage for the first time, or the use of cross-cultural styles such as Manipuri dance, Thai craft in stage design, or the Baul singing styles. This book is an exciting re-exploration of Tagore’s plays, visiting issues such as his contribution to Indian drama, drama and environment, feminist readings, postcolonial engagements, cross-cultural encounters, drama as performance, translational and adaptation modes, the non-translated or the non-translatable Tagore drama, Tagore drama in the 21st century, and Indian film. The volume serves as a wide-ranging and up-to-date resource on the criticism of Tagore drama, and will appeal to a range of Theatre and Performance scholars as well as those interested in Indian theatre, literature, and film.
The brief is the first to focus exclusively on environmentally friendly delivery of pesticides (controlled-release nanoparticulate formulation of pesticides using biodegradable polymers as carriers). The brief also introduces pesticides like Chlorpyrifos and biodegradable polymers like guar-gum. The brief will be extremely useful to the researchers in the field of agrochemicals and will be equally useful for advanced professionals in the field of biology, chemistry, environmental biology, entomology and horticulture.
IN THIS VOLUME: ‘Sagara Manthan’: Make in India Transition | Lt Gen JS Bajwa “Our vision in next 10 years is to become top defence industry in the world...” | Interview by Danvir Singh Indian Airborne Troops Script History | Danvir Singh Submarine Ahoy – Whither to Bound? | Rear Adm AP Revi Aerospace and Defence News | Priya Tyagi Higher Defence Organisation for India: Towards an Integrated Approach | Maj Gen Rajiv Narayanan Indian Army: Adopting ‘Deep Operations’ Doctrine | Col JK Achuthan The Government’s Burden of Military Security | Lt Gen Gautam Banerjee Global Terrorism: An Analysis of Fault Lines and Risks | Maj Gen SB Asthana Tackling Global Terror | Anil Kumar Tandale Islamic State: The New Brand of Terrorism in India | V Balasubramaniyan India & China Territorial Dispute: The Growing Challenge | Brig Gurmeet Kanwal China-India-Myanmar: The Forgotten Frontier | Air Cmde PC Chopra Myanmar and India: A New Future | Maj Gen Nitin P Gadkari Airfield Security: Lessons for the IAF | Air Marshal Anil Chopra Acoustic Capacity Building in the Indian Ocean Region | Cdr (Dr) Arnab Das & Vice Adm DSP Varma Transportation Infrastructure in the North East | Air Marshal Dhiraj Kukreja Our Forgotten Wars: Victimisation and Survival in Bodoland | Dr Samrat Sinha Women Officers in the Indian Army: A Reality Check | Lt Gen Mukesh Sabharwal Socio Economic Transformation: Through Ex-Servicemen | Lt Gen SK Gadeock & Col Nishant Sharma DPP 2016: A Missed Opportunity | Dr SN Misra Defence Budget 2016: Hits and Misses for the IAF | Air Marshal Anil Chopra Privatisation of the Indian Aerospace Industry: Problems and Prospects | Gp Capt AK Sachdev The Patrol Leader | Sumit Walia
This thesis examines the evidence for regulatory ubiquitination by focusing on A20. It provides an insightful and in-depth evaluation of the current literature by critically examining the evidence of K63-linked regulatory ubiquitination in regulating cell-signalling. It is also the first thesis to directly test the role of regulatory ubiquitination in NF-kB signaling in vivo. The case for regulatory ubiquitination has been to a large extent predicated upon the presumed deubiquitinase activity of A20, long considered a key regulator of inflammatory responses as mice lacking A20 die from multi-organ inflammation and cachexia. The theses reports the creation and characterization of a knock-in mouse that expresses a mutated form of A20 which selectively lacks the deubiquitinase activity. The knock-in mice surprisingly display completely normal NF-κB activation with no accompanying inflammatory phenotype. Given that the presumed role of A20 as a deubiquitinase has been used to support the importance of regulatory K63-linked ubiquitination in NF-kB signaling, this study will help focus future research efforts into alternative target pathways that do not depend on K63 ubiquitination. In fact, the work suggests that it might be important to revisit the role of K63-linked polyubiquitination in cell-signalling. Ubiquitin Chains: Degradation and Beyond is essential reading for anyone conducting research in cell-signalling and immunology. Dr. Arnab De received his PhD from the Department of Microbiology & Immunology at Columbia University. During his PhD, he developed transgenic mice to study the mechanism of action of a critical tumor-suppressor called A20. He is also well known for having developed peptide-based prodrugs as therapeutics for diabetes. His work has been reported by the media, and has resulted in multiple patents and publications in peer reviewed journals. He presented his findings at the American Peptide Symposium and was awarded the Young Investigator’s Award. He is the author of the book entitled Application of Peptide-Based Prodrug Chemistry in Drug Development, with a foreword written by Professor Jean Martinez (Former President, European Peptide Society) and published in the series SpringerBriefs in Pharmaceutical Science & Drug Development. His research interests lie at the intersection of chemistry and medicine. Besides biomedical research, he is also generally interested in public health policy and general scientific outreach.
Arnab Dey examines the intersecting role of law, ecology, and agronomy in shaping the history of tea and its plantations in British east India. He suggests that looking afresh at the legal, environmental, and agro-economic aspects of tea production illuminate covert, expedient, and often illegal administrative and commercial dealings that had an immediate and long-term human and environmental impact on the region. Critiquing this imperial commodity's advertised mandate of agrarian modernization in colonial India, Dey points to numerous tea pests, disease ecologies, felled forests, harsh working conditions, wage manipulation, and political resistance as examples of tea's unseemly legacy in the subcontinent. Dey draws together the plant and the plantation in highlighting the ironies of the tea economy and its consequences for the agrarian history of eastern India.
Macromolecular (specifically peptide-based) drugs could potentially be highly effective medicines. However they have a relatively short duration of action and variable therapeutic index. An example of such a peptide is Glucagon-like Peptide I which could potentially be used as a revolutionary drug for diabetes. This is because it stimulates insulin only when the blood glucose level is high thereby reducing the risk of hypoglycemia (a significant disadvantage of using insulin is that an insulin overdose is the single most potent cause of life-threatening hypoglycemia). However it’s short duration of action (half-life of 2 minutes in plasma) precludes its therapeutic use. In this volume, the use of novel therapeutics like GLP1 as an alternative to tradition insulin-based drugs in diabetes is described. Application of Peptide-Based Prodrug Chemistry in Drug Development elucidates the traditional concept of prodrugs as “specialized non-toxic protective groups used in a transient manner to alter or to eliminate certain limiting properties in the parent small molecule” (IUPAC definition). It goes on to provide insight into how prodrugs of peptides (with GLP1 as an example) could be appropriately used to extend the biological half life, broaden the therapeutic index of macromolecules and improve the pharmacodynamics of such drugs. Author explains the logic behind designing peptide prodrugs, synthetic procedures and bioassays to examine the conversion of the prodrug to the drug under therapeutic conditions. The prodrugs described slowly convert to the parent drug at physiological conditions of 37C and pH 7.2 driven by their inherent chemical instability without the need of any enzymatic cleavage. The diketopiperazine and diketomorpholine (DKP and DMP) strategies for prodrug conversion are demonstrated in detail with special emphasis on the chemical flexibility that it offers to develop prodrugs with variable time actions. This book will be of useful to chemists, biochemists, medicinal chemists, biologists and people in the medical profession (doctors). It may be used in undergraduate classes but will certainly help post-graduate students and advanced professionals. The author is grateful to Prof. Richard DiMarchi (Standiford H. Cox Professor of Chemistry and the Linda & Jack Gill Chair in Biomolecular Sciences at Indiana University) for valuable suggestions. The foreword for the book has been written by Prof. Jean Martinez, (Legion d'Honneur awarded by the French Republic; Professor of Chemistry and Medicinal Chemistry of the University of Montpellier, France; and Chairman of European Peptide Society, 2002-2010).
Game Science in Hybrid Learning Spaces explores the potential, implications, and impact of game-based approaches and interventions in response to the blurring of boundaries between digital and physical as well as formal and informal learning spaces and contexts. The book delves into the concept, opportunities, and challenges of hybrid learning, which aims to reduce the barriers of time and physical space in teaching and learning practices, fostering seamless, sustained, and measurable learning experience and outcomes beyond the barriers of formal education and physical learning contexts. Based on original research, Game Science in Hybrid Learning Spaces establishes trans-disciplinary and holistic considerations for further conceptual and empirical investigation into this topic, with the dual goals of a better understanding of the role of game-based approaches in a blended environment and of the possible structural and cultural transformation of formal education and lifelong learning. This book is an essential guide for researchers, designers, teachers, learners, and practitioners who want to better understand the relationship between games and learning that merges digital and physical experiences and blends formal and informal instructions.
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