Here, the authors introduce readers to solving molecular structure elucidation problems using the expert system ACD/Structure Elucidator. They explain in detail the concepts of the Computer-Assisted Structure Elucidation (CASE) approach and point out the crucial role of understanding the axiomatic nature of the data used to deduce the structure. Aspects covered include the main blocks of the expert system and essential features of the mathematical algorithms used. Graduate and PhD students as well as practicing chemists are provided with a detailed explanation of the various practical approaches depending on available spectral data peculiarities and the complexity of the unknown structure. This is supported by a large number of real-world completed examples, most of which are related to the structure elucidation of natural product molecules containing unusual skeletons. Dedicated software and further supplementary material are available at www.acdlabs.com/TeachingSE.
The Blogging Revolution is a colourful and revelatory account of bloggers around the globe who live and write under repressive regimes – many of them risking their lives in doing so. Antony Loewenstein’s travels take him to private parties in Iran and Egypt, internet cafes in Saudi Arabia and Damascus, to the homes of Cuban dissidents and into newspaper offices in Beijing, where he discovers the ways in which the internet is threatening the rule of governments. Through first-hand investigations, he reveals the complicity of Western multinationals in the restriction of information in these countries and how bloggers are leading the charge for change. The book also reveals some of the key players of the Arab Spring and how years of organising, web dissent and bravery led to momentous changes in US-backed dictatorships across the Middle East in 2010 and 2011. The Blogging Revolution is a superb examination of the nature of repression in the twenty-first century and the power of brave individuals to overcome it.
Measuring Ocean Currents: Tools, Technologies, and Data covers all major aspects of ocean current measurements in view of the implications of ocean currents on changing climate, increasing pollution levels, and offshore engineering activities. Although more than 70% of the Earth is covered by ocean, there is limited information on the countless fine- to large-scale water motions taking place within them. This book fills that information gap as the first work that summarizes the state-of-the-art methods and instruments used for surface, subsurface, and abyssal ocean current measurements. Readers of this book will find a wealth of information on Lagrangian measurements, horizontal mapping, imaging, Eulerian measurements, and vertical profiling techniques. In addition, the book describes modern technologies for remote measurement of ocean currents and their signatures, including HF Doppler radar systems, satellite-borne sensors, ocean acoustic tomography, and more. Crucial aspects of ocean currents are described in detail as well, including dispersion of effluents discharged into the sea and transport of beneficial materials—as well as environmentally hazardous materials—from one region to another. The book highlights several important practical applications, showing how measurements relate to climate change and pollution levels, how they affect coastal and offshore engineering activities, and how they can aid in tsunami detection. Coverage of measurement, mapping and profiling techniques Descriptions of technologies for remote measurement of ocean currents and their signatures Reviews crucial aspects of ocean currents, including special emphasis on the planet-spanning thermohaline circulation, known as the ocean's "conveyor belt," and its crucial role in climate change
THE NUMBER ONE BESTSELLER - REISSUED WITH A NEW FOREWORD FOR THE 75TH ANNIVERSARY 'Magnificent, vivid, moving, superb' Max Hastings, Sunday Times ______________ This is the closest you will ever get to war - the taste, the smell, the noise and the fear The Normandy Landings that took place on D-Day involved by far the largest invasion fleet ever known. The scale of the undertaking was awesome and what followed was some of the most cunning and ferocious fighting of the war. As casualties mounted, so too did the tensions between the principal commanders on both sides. Meanwhile, French civilians caught in the middle of these battlefields or under Allied bombing endured terrible suffering. Even the joys of Liberation had their darker side. Antony Beevor's inimitably gripping narrative conveys the true experience of war. He lands the reader on the beach alongside the heroes whose stories he so masterfully renders in their full terrifying glory. ______________ 'A thrilling story, with all Beevor's narrative mastery' Chris Patten, Financial Times 'Beevor's D-Day has all the qualities that have made his earlier works so successful: an eye for telling and unusual detail, an ability to make complex events understandable, and a wonderful graphic style' Ian Kershaw, Guardian, Books of the Year 'D-Day's phenomenal success is both understandable and justified' James Holland 'D-Day is a triumph . . . on almost every page there's some little detail that sticks in the mind or tweaks the heart. This is a terrific, inspiring, heart-breaking book' Sam Leith, Daily Mail
With philosophy so steeped in patriarchal tradition how is it possible for feminists to work within it? In this volume, 13 feminist theorists discuss whether traditional ideals of objectivity and rationality should be given a place within the committed feminist view of philosophy and the world.
A lifeline for anxiety sufferers, this expertly crafted workbook has been revised and updated to be even more user-friendly. Readers discover a new sense of freedom as they work through this comprehensive program grounded in cognitive-behavioral therapy (CBT). Step by step, the book provides skills for changing anxiety-provoking ways of thinking and for confronting feared situations safely and gradually. Updated with over a decade's worth of research advances, the second edition includes more detailed instructions for customizing the program, extra support for staying motivated, vivid stories that run throughout the book, new separate chapters on relaxation and mindfulness, and downloadable audio recordings. The large-size format makes it easy to fill in the worksheets; readers can download and print additional copies as needed"--
The little-known drama of the last-minute decision to launch the invasion of Normandy—excerpted from the internationally bestselling D-Day: The Battle for Normandy In D-Day: The Decision to Launch, excerpted from Antony Beevor’s bestselling book D-Day: The Battle for Normandy, readers get the little-known story of how the difficult decision was made to launch the Allied invasion of France on June 6, 1944. The stakes could not have been higher: if Operation Overlord were to fail, it would be a crushing blow to the Allies, a huge loss of both men and equipment. The decision of when to launch rested with supreme commander General Dwight D. Eisenhower, but it hinged on one factor: the weather. If there was too much cloud cover, the Allied bombers wouldn’t be able to provide air support, and if the seas were too rough, the landing craft would be swamped. It fell to one man to predict the weather: Dr. James Stagg, the head of the meteorological team at Supreme Headquarters Allied Expeditionary Force. This riveting selection from D-Day, praised by Time as “a vibrant work of history that honors the sacrifice of tens of thousands of men and women,” tells the fascinating inside story of one of the most important decisions of World War II.
Investigating Seafloors and Oceans: From Mud Volcanoes to Giant Squid offers a bottom-to-top tour of the world’s oceans, exposing the secrets hidden therein from a variety of scientific perspectives. Opening with a discussion of the earth’s formation, hot spots, ridges, plate tectonics, submarine trenches, and cold seeps, the text goes on to address such topics as the role of oceans in the origin of life, tidal bore, thermal effects, ecosystem services, marine creatures, and nutraceutical and pharmaceutical resources. This unique reference provides insight into a wide array of questions that researchers continue to ask about the vast study of oceans and the seafloor. It is a one-of-a-kind examination of oceans that offers important perspectives for researchers, practitioners, and academics in all marine-related fields. Includes chapters addressing various scientific disciplines, offering the opportunity for readers to gain insights on diverse topics in the study of oceans Provides scientific discussion on thermo-tolerant microbial life in sub-seafloor hot sediments and vent fields, as well as the origin of life debates and the puzzles revolving around how life originated Includes detailed information on the origin of dreaded episodes, such as volcanic eruptions, earthquakes, tsunamis, internal waves and tidal bores Contains information on the contribution of the oceans in terms of providing useful nutraceutical and pharmaceutical products
Computer-Assisted Structure Elucidation (CASE) systems are a combination of software algorithms and tools to support and enable chemists and spectroscopists engaged in the process of molecular structure elucidation via the analysis of spectroscopic data. These expert systems dramatically reduce the time associated with structure elucidation and improve the reliability of the results. Contemporary Computer-Assisted Approaches to Molecular Structure Elucidation describes the principles on which these expert systems for spectroscopic structure elucidation are based and concisely explains the algorithmic concepts behind the programs. The authors use their own personal experiences in the development of the Structure Elucidator (StrucEluc) CASE software system to discuss the present state-of-the-art in computer-assisted structure elucidation. Scientists that are presently using CASE systems will be interested in the algorithms and modern approaches and for organizations that are currently using the StrucEluc platform the book is designed to help researchers understand the strategies behind CASE as well as details regarding the StrucEluc platform. For scientists that have never used CASE systems they will now have access to all necessary information to understand CASE systems for mastering this new and very effective approach to structure elucidation. The authors overall goal is writing this book is to produce the 'must read' definitive text that will represent the results of decades of work to develop computer-assisted structure elucidation software systems. CASE systems are now powerful software tools commonly outperforming and correcting human interpretations of data. This book will also provide an historical perspective of the work of the founding fathers of the technique and identify the challenges that have been overcome to produce modern CASE systems.
This is a study of the landed gentry of north Wales from the Edwardian conquest in the thirteenth century to the incorporation of Wales in the Tudor state in the sixteenth. The limitation of the discussion to north Wales is deliberate; there has often been a tendency to treat Wales as a single region, but it is important to stress that, like any other country, it is itself made up of regions and that a uniformity based on generalisation cannot be imposed. This book describes the development of the gentry in one part of Wales from an earlier social structure and an earlier pattern of land tenure, and how the gentry came to rule their localities. There have been a number of studies of the medieval English gentry, usually based on individual counties, but the emphasis in a Welsh study is not necessarily the same as that in one relating to England. The rich corpus of medieval poetry addressed to the leaders of native society and the wealth of genealogical material and its potential are two examples of this difference in emphasis.
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