Les produits à base de cannabis dans le traitement de diverses maladies, y compris l’épilepsie, connaissent un essor grandissant, et intéressent de plus en plus les scientifiques. Un grand nombre d’études a été publiée les 15 dernières années, démontrant l’efficacité de ces produits dans le contrôle d’un large spectre d’épisode épileptiques, en particulier ceux observés dans les cas graves d’épilepsie pédiatrique, comme les syndromes Lennox-Gastaut et Dravet. Ce livre, rédigé par des spécialistes du domaine, présente des analyses critiques des données récentes issues d’essais cliniques. Les auteurs et autrices évoquent des sujets comme la pharmacologie, les interactions entre drogues, leur efficacité, effets secondaires potentiels et effets à long-terme sur le développement et le comportement. Les neurologues et tous les cliniciens ayant des patients épileptiques trouveront des informations utiles concernant les meilleures pratiques. ----------------------------------------------------------------------------------- There has been growing interest in the use of cannabis-based products for the treatment of a wide range of diseases, including epilepsy. A number of studies were published during the last 5 years demonstrating efficacy of purified CBD for the control of a large spectrum of seizure-types, particularly those observed in severe childhood epilepsies, such as Lennox-Gastaut and Dravet syndromes. This book, co-authored by leaders in the field of epileptology, critically reviews recent data from clinical trials. Authors discuss issues related to pharmacology, drug interactions, efficacy, potential adverse events and long-term effects on development and behaviour. Child and adult neurologists and all clinicians contributing to epilepsy care will find useful information on the best practices, when using purified CBD for the treatment of drug-resistant epilepsies.
Since 1984, the year of the publication of its first edition, the famous “Blue Guide” has been the international reference for paediatricians and neuropaediatricians with regard to epileptic syndromes in infants, children and adolescents. This 6th edition reviews some of the most noteworthy developments in the field, particularly in epileptic syndromes, but also focuses on the genetic aspects of the syndromes and their development. Progress brought about by advances in neuroimaging is also discussed in addition to specific etiologies such as parasitic diseases and immune and autoimmune diseases. The different backgrounds of the contributors - coordinators and authors – ensure that the book’s longstanding reputation for objectivity and seriousness, built over almost 35 years, remain well-deserved. This book written by the current leading specialists is recognized worldwide as the international reference in epilepsy.
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