The liver is a complex organ due to its unique microscopic structure, intricate metabolic functions and susceptibility to a wide variety of insults, manifesting in countless histological patterns. Atlas of Liver Pathology considers both changes seen in medical liver biopsies as well as lesional biopsies when the specimen has been taken from a mass. The book starts by reviewing normal structure and its variants and the optimal approaches for the preparation of histological sections for diagnostic liver pathology. The following chapters are dedicated to developmental, metabolic, infectious, drug related, autoimmune, biliary, vascular and neoplastic disorders. Two sections on liver pathology in pregnancy and transplantation conclude the work. Macroscopic illustrations are included where appropriate. All photographs are complemented by legends describing the picture and providing relevant related information. Authored by nationally and internationally recognized pathologists, Atlas of Liver Pathology is a valuable resource that serves as a quick reference guide for the diagnosis of usual and unusual diseases.
The Handbook of Crime Correlates, Second Edition summarizes more than a century of worldwide research on traits and social conditions associated with criminality and antisocial behavior. Findings are provided in tabular form, enabling readers to determine at a glance the nature of each association. Within each table, results are listed by country, type of crime (or other forms of antisocial behavior), and whether each variable is positively, negatively, or insignificantly associated with offending behavior. Criminal behavior is broken down according to major categories, including violent crime, property crime, drug offenses, sex offenses, delinquency, and recidivism. This book provides a resource for practitioners and academics who are interested in criminal and antisocial behavior. It is relevant to the fields of criminology/criminal justice, sociology, and psychology. No other publication provides as much information about how a wide range of variables—e.g., gender, religion, personality traits, weapons access, alcohol and drug use, social status, geography, and seasonality—correlate with offending behavior. - Includes 600+ tables regarding variables related to criminal behavior - Consolidates 100+ years of academic research on criminal behavior - Findings are identified by country and world regions for easy comparison - Lists criminal-related behaviors according to major categories - Identifies universal crime correlates
Commensurate with an emphasis on evidence-based practice and health competencies to improve patient outcomes, get a solid foundation in cardiovascular and pulmonary physiology and rehabilitation! Cardiovascular and Pulmonary Physical Therapy: Evidence and Practice, 6th Edition provides a holistic, person-centered approach to the spectrum of cardiovascular and pulmonary physical therapy. From examination and evaluation to interventions, this book guides you through the health promotion strategies for maximizing patients' health and wellbeing, in conjunction with managing the needs of patients with acute and chronic conditions, those in intensive care units, and of special populations such as children and elders. Selected case studies translate related scientific research into evidence-based practice and enhance clinical decision making. Now including an enhanced eBook version (with print purchase), this text details the latest best practices to help achieve the best physical therapy outcomes. - Coverage of evidence-based practice includes the latest research from leading top-tier journals to support physical therapist clinical reasoning and decision making. - Realistic scenarios and case examples show the application of concepts to evidence-based practice. - Holistic approach supports treating the whole person rather than just the symptoms of a disease or disorder, covering medical, physiological, psychological, psychosocial, therapeutic, practical, and methodological aspects. - Full-color photos and illustrations enhance your understanding of the book's concepts, ideas, and management considerations. - Emphasis on the terminology and guidelines of the APTA's Guide to Physical Therapist Practice keeps the book consistent with the practice standards in physical therapy, including the International Classification of Functioning, Disability and Health. - Primary and secondary cardiovascular and pulmonary conditions are emphasized, along with their co-existence. - Multimorbidity focus is used rather than a single-disease framework, with attention to implications for assessment, management, and evaluation. - Integrated approach to oxygen transport demonstrates how the cardiovascular and pulmonary systems function interdependently to support all organ systems. - Key terms and review questions in each chapter focus your learning on important concepts and translating these into practice. - NEW! Updated content reflects the latest research and clinical practice in the field. - NEW! eBook version included only with print purchase allows you to access all the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. - NEW! Video clips, interviews with authors and other experts in their fields, and more are available in the eBook version included only with print purchase. - NEW! Expanded contributions from experts from multiple countries maximize the validity of content.
The author team welcomes a new coauthor, Sean B. Carroll, a recognized leader in the field of evolutionary development, to this new edition of Introduction to Genetic Analysis (IGA). The authors’ ambitious new plans for this edition focus on showing how genetics is practiced today. In particular, the new edition renews its emphasis on how genetic analysis can be a powerful tool for answering biological questions of all types. Special Preview available.
Non-neoplastic diseases are the focus of coverage in this issue of Surgical Pathology Clinics. Topics include: Non-neoplastic diseases in kidney cancer; Nephrectomy for non-neoplastic causes; Autopsy renal pathology; Practical approach to kidney donation workup; Kidney allograft pathology; Renal infections; Amyloidosis - all subtypes; Histologic classifications in renal pathology - pros and cons; Renal molecular pathology; Emerging concepts and controversies in renal pathology. This issue is intended for surgical pathologists and those with clinical practices in diagnostic renal pathology and kidney research. Anthony Chang, whose clinical practice and research is focused on renal pathology, leads this issue.
Vitamin D: The Calcium Homeostatic Steroid Hormone provides a continuing coordinated group of edited critiques of the dynamic state of the science and art of nutrition. The most recent basic advances will be reviewed within the broad framework of the scientific knowledge of food and nutrition, including its application to man, individually and societally. The volumes, authored singly or by invited contributors, will appeal to serious scholars concerned with pure or applied nutrition. This volume comprises 13 chapters, with the first discussing the progress of vitamin D-cholecalciferol from vitamin to steroid hormone. Succeeding chapters then discuss the biological and chemical assay of vitamin D, its metabolites, and analogs; metabolism of vitamin D; and the tissue and subcellular localization of vitamin D and its metabolites. Other chapters cover binding proteins and receptors for vitamin D and its metabolites; interrelationships between vitamin D and other hormones; intestinal effects of vitamin D; vitamin D actions in the kidney; vitamin D actions on bone; and vitamin D and its clinical relationships. This book will be of interest to practitioners in the fields of chemistry, nutrition, and medicine.
The liver is a complex organ due to its unique microscopic structure, intricate metabolic functions and susceptibility to a wide variety of insults, manifesting in countless histological patterns. Atlas of Liver Pathology considers both changes seen in medical liver biopsies as well as lesional biopsies when the specimen has been taken from a mass. The book starts by reviewing normal structure and its variants and the optimal approaches for the preparation of histological sections for diagnostic liver pathology. The following chapters are dedicated to developmental, metabolic, infectious, drug related, autoimmune, biliary, vascular and neoplastic disorders. Two sections on liver pathology in pregnancy and transplantation conclude the work. Macroscopic illustrations are included where appropriate. All photographs are complemented by legends describing the picture and providing relevant related information. Authored by nationally and internationally recognized pathologists, Atlas of Liver Pathology is a valuable resource that serves as a quick reference guide for the diagnosis of usual and unusual diseases.
Thousands of imaginative scientists, over more than a century, have revealed the fascinating story of intracellular calcium, through a pathway of ingenious invention and discovery. Intracellular Calcium, the definitive book on this topic, reveals: The pathway of discovery and invention of intracellular calcium over more than 100 years. The evidence for intracellular calcium as a universal switch in all animal, plant, fungal and microbial cells How the components required for calcium signalling are named and classified. The ingenious technology, which has been developed to study intracellular calcium. How calcium is regulated inside cells and how it works to trigger an event. The role of intracellular calcium in disease, cell injury and cell death. How many drugs work through the calcium signalling system. How intracellular calcium is involved in the action of many natural toxins. How the intracellular calcium signalling system has evolved over 4000 million years, showing why it was crucial to the origin of life. A key principle presented throughout the book is the molecular variation upon which the intracellular calcium signalling system depends. This variation occurs within the same cell type and between cells with different functions, providing the invisible matrix upon which Darwin and Wallace’s Natural Selection depends. Featuring more than 100 figures, including detailed chemical structures as well as pictures of key pioneers in the field, a bibliography of more than 1500 references, as well as detailed subject and organism indices, this definitive work provides a unique source of scholarship for teachers and researchers in the biomedical sciences and beyond.
This new volume of the Biopsy Interpretation Series is a practical, superbly illustrated guide to the technical and interpretive aspects of a frozen section. The focus is on use of the frozen section in intraoperative management of patients, particularly those with tumors. The authors give pathologists a thorough knowledge of the utility and limitations of a frozen section, the appropriate circumstances for doing one, the proper techniques, and the interpretation and reporting of results. The book features more than 300 full-color gross and microscopic images, with discussions of differential diagnosis. A companion Website will provide 300 additional figures, plus a test bank that is ideal for board exam preparation.
Starting from first principles, this book introduces the closely related phenomena of Bose condensation and Cooper pairing, in which a very large number of single particles or pairs of particles are forced to behave in exactly the same way, and explores their consequences in condensed matter systems. Eschewing advanced formal methods, the author uses simple concepts and arguments to account for the various qualitatively new phenomena which occur in Bose-condensed and Cooper-paired systems, including but not limited to the spectacular macroscopic phenomena of superconductivity and superfluidity. The physical systems discussed include liquid 4-He, the BEC alkali gases, "classical" superconductors, superfluid 3-He, "exotic" superconductors and the recently stabilized Fermi alkali gases. The book should be accessible to beginning graduate students in physics or advanced undergraduates.
This must-have clinical reference, by Drs. Amy S. Paller and Anthony J. Mancini, provides practical, authoritative guidance for identification and management of all types of skin disorders seen in children and adolescents. Hurwitz Clinical Pediatric Dermatology, 5th Edition, is ideal for pediatricians, dermatologists, family practitioners and anyone who sees children with skin disorders – no matter what level of experience you may have. Benefit from the knowledge and expertise of two leaders in the field, who provide a clearly written, consistent approach throughout the text. Stay on the cutting edge of what’s new in pediatric dermatology – from the neonate to the adolescent - with the latest drug developments and disease classifications. Recognize virtually any skin condition you’re likely to see thanks to more than 1,000 high-quality color images, including over 300 brand new to this edition. Find the most appropriate therapy options with updated evidence based guidance. Easily locate the information you need with more quick-reference boxes and summary tables throughout the text.
For a long time membrane biochemistry was almost synonymous with the bio chemistry of electron transport and oxidative phosphorylation. Although the successful analysis of hormone receptors, active transport, and other membrane-linked metabolic systems displaced mitochondria from the focus of interest, the field continued to grow and its contributions to other areas of membrane biochemistry played a major role in their dramatic development. The eight chapters in this volume dealing with electron transport provide a concise, critical, and up-to-date picture of the problems and accomplishments of the field. In the remainder of the volume a brief summary of selected receptor functions is presented. The relative novelty of this field naturally limits the factual scope of developments and encourages speculation. Nevertheless these reviews accurately reflect both accomplishments and deficiencies and provide objective guidance for future development. Several receptor functions omitted from these discussions will form one of the later volumes currently in preparation.
The technology used to ripen bananas is affected by a wide range of factors, including the cultivar, growing conditions, harvesting method, and maturity at which the fruit are harvested and handled. Various post harvest treatments applied to fruit can also impact ripening. While many textbooks have been dedicated to Musa (bananas and plantains), none have focused exclusively on the ripening process. The commercial ripening of bananas and the chemical changes that occur thereby are considered here in detail. In developed, temperate countries where bananas are imported, successful ripening technologies have evolved. Most bananas, however, are marketed locally in the country where they are grown, and often the ripening technologies used have economic and health implications. This brief offers an in-depth discussion of not only the implications of these technologies, but also of alternative ripening methods and their commercial applications. For an understanding of both the chemical basis by which bananas ripen and the technologies used to control the process, look no further than this essential text.
Neurodegenerative diseases are major contributors to disability and disease, with Alzheimer's and Parkinson's diseases the most prevalent. This major reference reviews the rapidly advancing knowledge of pathogenesis and treatment of neurodegenerative diseases in the context of a comprehensive survey of each disease and its clinical features. The editors and contributors are among the leading experts in the field internationally. Covering basic science, diagnostic tools and therapeutic approaches, the book focuses on all aspects of neurodegenerative disease, including the normal aging process. The dementias, prion diseases, Parkinson's disease and atypical parkinsonisms, neurodegenerative ataxias, motor neuron diseases, degenerative diseases with chorea, iron and copper disorders, and mitochondrial diseases, are all methodically presented and discussed, with extensive illustrations. In each case the underlying genetics, neuropathological and clinical issues are fully reviewed, making this the most complete as well as the most authoritative reference available to clinicians and neuroscientists.
Now in its Fifth Edition, Crofton and Douglas's Respiratory Diseases has firmly established itself as the leading clinical textbook on diseases of the chest. Presented, for the first time, as a two-volume set, this classic text has been completely rewritten and greatly expanded. Extensive revisions ensure that these volumes present an up-to-date review of all aspects of lung disease . The contributions of some 18 leading authorities ensure that each area is comprehensively covered and new to this edition are chapters on the genetics of lung disease, smoking, air pollution, sleep apnoea, diving, lung transplantation and medico-legal aspects. The changes in content reflect the pace of change in the areas concerned not only in terms of understanding of the disease processes but also their treatment. The single chapter on asthma that appeared in previous editions, has now been expanded into three chapters covering epidemiology, mechanisms and management, reflecting the enormous research effort currently underway following a marked increase in the incidence of this disease in recent years. This new edition continues to provide an excellent reference both for the trainee and specialist in respiratory medicine, as well as the general physician. It will be extremely useful on the ward and in the office, where clinical problems arise and questions are asked which need clear answers.
This atlas is designed to be a user-friendly bench-side reference for pathology trainees and general pathologists in handling and interpreting specimens of hepatocellular carcinoma. It provides over 550 high-quality gross and microscopic photos focusing on hepatocellular carcinoma and its mimickers, and demonstrating a full range of various histological variants of hepatocellular carcinoma. Introductory text in each chapter summarises salient clinical associations, pathological features, and molecular alterations of different variants of hepatocellular carcinoma. Differentiation between hepatocellular carcinoma and its mimickers is illustrated through various case studies. The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high.The authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high./divThe authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high./divThe authors are nationally and internationally recognized hepatopathologists in the Asian-Pacific regions (Hong Kong, Korea, the Philippines, and Singapore), in which the incidence of hepatocellular carcinoma is high./div
Published in 1999, this text investigates whether FDI caused spill over effects which have led to the economic growth of the ASEAN-5 economies, and if that it so, whether the ASEAN Preferential Trade Agreement (APTA) had a significant effect in attracting FDI to the region. It takes into account the different levels of economic development of the countries under analysis. The results from the structural (static) model suggest that FDI has stimulated economic growth through the human factors followed by technology transfer, international trade, and learning by doing, and that the formation of APTA had a lagged influence on FDI inflows into the advantage of the more developed member countries and the disadvantage of the less developed countries. Those from the multiplier (dynamic) effects analysis demonstrate that whereas the impact is immediate in the more developed, politically stable and foreign investment friendly economies, there is a time lag in those economies which are less developed and more hostile to FDI. The analysis presents an empirical comparison of how the level of economic development affects the interaction of FDI, regionalism and economic growth.
- Restructured and presented in 3 parts: - Section 1: Positioning Practice describes the context and importance of nursing in mental health and includes a new chapter on self-care - Section 2: Knowledge for Practice addresses the specialist practice of mental health nursing. Each chapter examines specific mental health conditions, assessment, nursing management and relevant treatment approaches - Section 3: Contexts of practice features scenario-based chapters with a framework to support mental health screening, assessment, referral and support, across a range of clinical settings
2014 BMA Medical Book Awards Highly Commended in Radiology category! Image-Guided Interventions, a title in the Expert Radiology Series, brings you in-depth and advanced guidance on all of today?s imaging and procedural techniques. Whether you are a seasoned interventionalist or trainee, this single-volume medical reference book offers the up-to-the-minute therapeutic methods necessary to help you formulate the best treatment strategies for your patients. The combined knowledge of radiology experts from around the globe provides a broad range of treatment options and perspectives, equipping you to avoid complications and put today's best approaches to work in your practice. "... the authors and editors have succeeded in providing a book that is both useful, instructive and practical" Reviewed by RAD Magazine, March 2015 Formulate the best treatment plans for your patients with step-by-step instructions on important therapeutic radiology techniques, as well as discussions on equipment, contrast agents, pharmacologic agents, antiplatelet agents, and protocols. Make effective clinical decisions with the help of detailed protocols, classic signs, algorithms, and SIR guidelines. Make optimal use of the latest interventional radiology techniques with new chapters covering ablation involving microwave and irreversible electroporation; aortic endografts with fenestrated grafts and branch fenestrations; thoracic endografting (TEVAR); catheter-based cancer therapies involving drug-eluting beads; sacroiliac joint injections; bipedal lymphangiography; pediatric gastrostomy and gastrojejunostomy; and peripartum hemorrhage. Know what to look for and how to proceed with the aid of over 2,650 state-of-the-art images demonstrating interventional procedures, in addition to full-color illustrations emphasizing key anatomical structures and landmarks. Quickly reference the information you need through a functional organization highlighting indications and contraindications for interventional procedures, as well as tables listing the materials and instruments required for each. Access the fully searchable contents, online-only material, and all of the images online at Expert Consult.
Thoroughly updated and revised in line with the latest World Health Organization classification system, the second edition of Diagnostic Lymph Node Pathology continues to be an essential guide to the interpretation of lymph node biopsies for all professional and trainee general pathologists and haematopathologists alike. Tthe new edition covers both classical and less well known features of individual disease processes together with the differential diagnoses of lymph node biopsy specimens. B-cell lymphomas have been reorganized in line with WHO guidelines. Topics such as Epstein-Barr virus, age-related lymphomas and prognostic indicators have been expanded, and new cases using needle core biopsies are presented.
Crystal Structure Refinement is a mixture of textbook and tutorial. As A Crystallographers Guide to SHELXL it covers advanced aspects of practical crystal structure refinement, which have not been much addressed by textbooks so far. After an introduction to SHELXL in the first chapter, a brief survey of crystal structure refinement is provided. Chapters three and higher address the various aspects of structure refinement, from the treatment of hydrogen atoms to the assignment of atom types, to disorder, to non-crystallographic symmetry and twinning. One chapter is dedicated to the refinement of macromolecular structures and two short chapters deal with structure validation (one for small molecule structures and one for macromolecules). In each of the chapters the book gives refinement examples, based on the program SHELXL, describing every problem in detail. It comes with a CD-ROM with all files necessary to reproduce the refinements.
This title was first published in 2002: Anthony Bende-Nabende focuses on the ongoing globalization process, which has sparked an unprecedented world-wide debate. He provides a one-stop centre for a balanced coverage of the theoretical, empirical and policy issues linking globalization with foreign direct investment, regional economic integration, and economic growth and sustainable development. This stimulating book comprehensively explores the theoretical and empirical literature inter-linking the aforementioned factors from the anti-globalization activists’ viewpoint, and from the pro-globalization proponents’ perspective. It proposes policies that individual countries should pursue, based on the recognition that globalization generates both positive and negative effects. These comprise policies required to maximise the economic benefits globalization may generate, and those that aim to eliminate or at least minimize the negative development-oriented effects globalization may engender and, hence, to propel sustainable development. The book will be an essential guide for students, academics and those involved in international economics, environmental studies, international relations, and growth and development studies.
Kidney disease and cancer are frequent comorbidities that require specialized knowledge and expertise from both the nephrologist and the oncologist. Written by three pioneers in this growing subspecialty, Onco-Nephrology provides authoritative, definitive coverage of the mechanism and management of these two life-threatening diseases. This unique, single-volume resource covers current protocols and recommends management therapies to arrest kidney failure and allow oncologic treatments to continue and succeed. - Addresses acute and chronic kidney diseases that develop from a variety of cancers. This includes direct kidney injury from the malignancy, paraneoplastic effects of the cancer, and various cancer agents used to treat the malignancy. - Discusses key issues regarding kidney disease in patients with cancer, including conventional chemotherapeutic regimens and new novel therapies (targeted agents and immunotherapies) or the malignancies themselves that may promote kidney injury; patients with chronic kidney disease who acquire cancer unrelated to renal failure; and kidney transplantation, which has been shown to carry an increased risk of cancer. - Contains dedicated chapters for each class of the conventional chemotherapeutic agents, targeted cancer agents, and cancer immunotherapies including the basic science, pathogenic mechanisms of injury, clinical manifestations, and treatment. - Includes special chapters devoted to the individual classes of chemotherapies that relate to kidney disease for quick reference. Discusses increasingly complex problems due to more numerous and specialized anti-cancer drugs, as well as increased survival rates for both cancer and renal failure requiring long-term patient care. - Covers anti-VEGF (antivascular endothelial growth factor) agents and cancer immunotherapies – treatments that are being recognized for adverse kidney effects. - Utilizes a clear, logical format based on the ASN Core Curriculum for Onco-Nephrology, making this reference an excellent tool for board review, as well as a practical resource in daily practice. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
The new edition of this classic textbook has now been extensively revised by a team of five authors, yet it follows the tradition of the original single-authored book. It continues to provide a comprehensive review of the cognitive, emotional and behavioural consequences of cerebral disorders and their manifestations in clinical practice. Enabling clinicians to formulate incisive diagnoses and appropriate treatment strategies.
Psychology: from inquiry to understanding 2e continues its commitment to emphasise the importance of scientific-thinking skills. It teaches students how to test their assumptions, and motivates them to use scientific thinking skills to better understand the field of psychology in their everyday lives. With leading classic and contemporary research from both Australia and abroad and referencing DSM-5, students will understand the global nature of psychology in the context of Australia’s cultural landscape.
Provides techniques for diagnosis and treatment of concussion and other injuries to the head, spine, and peripheral nervous system. This evidence-based reference bridges the gap between principles and practice to better manage these serious injuries.
Provides both historical information and the latest toxicological data on various classes of food additives--examining the production, application, and safety of numerous compounds used to enhance and preserve the quality of foods.
Written and edited by international leaders in the field, this book has, through two best-selling editions, been the place to turn for authoritative answers to your toughest challenges in clinical immunology. Now in full color and one single volume, the 3rd Edition brings you the very latest immunology knowledge - so you can offer your patients the best possible care. The user-friendly book and the fully searchable companion web site give you two ways to find the answers you need quickly...and regular online updates keep you absolutely current. Leading international experts equip you with peerless advice and global best practices to enhance your diagnosis and management of a full range of immunologic problems. A highly clinical focus and an extremely practical organization expedite access to the answers you need in your daily practice. Cutting-edge coverage of the human genome project, immune-modifier drugs, and many other vital updates keeps you at the forefront of your field. A new organization places scientific and clinical material side by side, to simplify your research and highlight the clinical relevance of the topics covered. A multimedia format allows you to find information conveniently, both inside the exceptionally user-friendly book and at the fully searchable companion web site. Regular updates online ensure that you'll always have the latest knowledge at your fingertips. Includes many new and improved illustrations and four color design. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
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