This first monograph in the new AAPS book series concisely reviews important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance. Drs. Hickey and Giovagnoli have written an essential primer for any scientists involved in powder or particle research and manufacturing. It is appropriate for those just entering the field or as a rapid reference for the experienced pharmaceutical scientist. The authors have both academic and industrial experience and the coverage includes solid state chemistry; crystallization; physical processes; particle size and distribution;particle interaction;manufacturing processes;quality by design;and a general discussion of the industry. Pharmaceutical Powder and Particles is intended to concisely review important aspects of powder and particle systems and the critical quality attributes that should be used as a guide to future developments intended to maximize the control of product quality and performance.
Inhaled Pharmaceutical Product Development Perspectives: Challenges and Opportunities describes methods and procedures for consideration when developing inhaled pharmaceuticals, while commenting on product development strategies and their suitability to support regulatory submission. It bridges the gap between the aspirations of scientists invested in new technology development and the requirements that must be met for any new product. The book brings together emerging analytical and inhalation technologies, providing perspectives that illuminate formulation and device design, development, regulatory compliance, and practice. Focusing on underlying scientific and technical principles known to be acceptable from the current regulatory perspective, this monograph will remain useful as a high-level guide to inhaled product development for the foreseeable future. - Discusses development strategies and best practices in the context of regulatory requirements - Written by a broadly qualified expert drawing on the knowledge and critical opinions of key individuals in the field - Includes a foreword by Charles G. Thiel
Non-linear phenomena pervade the pharmaceutical sciences. Understanding the interface between each of these phenomena and the way in which they contribute to overarching processes such as pharmaceutical product development may ultimately result in more efficient, less costly and rapid implementation. The benefit to Society is self-evident in that affordable treatments would be rapidly forthcoming. We have aggregated these phenomena into one topic “Pharmaco-complexity: Non-linear Phenomena and Drug Product Development”.
Written by two leaders in the field of pediatric dermatology, this classic text provides both detailed content for the specialist and easily accessible information for the non-dermatologist and less experienced clinician. Paller and Mancini – Hurwitz Clinical Pediatric Dermatology, 6th Edition, comprehensively covers the full range of skin disorders in children, offering authoritative, practical guidance on diagnosis and treatment in a single volume. This award-winning, evidence-based text has been fully revised and updated, and is an essential resource for anyone who sees children with skin disorders. - Features new content outline boxes for faster navigation, hundreds more clinical images, and authors' tips for the diagnosis and treatment of pediatric skin diseases. - Contains updated, evidence-based guidance and the latest drug developments and disease classifications. - Provides a careful balance of narrative text, useful tables, and 1,300 high-quality clinical photographs, helping you recognize virtually any skin condition you're likely to see. - Includes a greatly expanded discussion of atopic dermatitis and psoriasis and new therapeutic approaches for treating genetic disorders and systemic diseases such as ichthyoses and rheumatologic disorders. - Discusses new tests for subclassifying disease, such as the myositis-specific antibodies of juvenile dermatomyositis, genotyping, and immunophenotypes of inflammatory skin disorders. - Contains new and updated tables on psoriasis co-morbidities, genetic syndrome classifications, acne therapies, pediatric histiocytoses, PHACE syndrome criteria, HSV therapies and juvenile dermatomyositis. - Features updated sections on infections, exanthems, vascular disorders, dermatoses and genodermatoses. - Discusses hot topics such as the use of stem cell and cell therapy, as well as recombinant protein, for treating epidermolysis bullosa; the resurgence of measles; congenital Zika virus infections; and much more.
This must-have clinical reference, by Drs. Amy S. Paller and Anthony J. Mancini, provides practical, authoritative guidance for identification and management of all types of skin disorders seen in children and adolescents. Hurwitz Clinical Pediatric Dermatology, 5th Edition, is ideal for pediatricians, dermatologists, family practitioners and anyone who sees children with skin disorders – no matter what level of experience you may have. Benefit from the knowledge and expertise of two leaders in the field, who provide a clearly written, consistent approach throughout the text. Stay on the cutting edge of what’s new in pediatric dermatology – from the neonate to the adolescent - with the latest drug developments and disease classifications. Recognize virtually any skin condition you’re likely to see thanks to more than 1,000 high-quality color images, including over 300 brand new to this edition. Find the most appropriate therapy options with updated evidence based guidance. Easily locate the information you need with more quick-reference boxes and summary tables throughout the text.
In nature, microorganisms are generally found attached to surfaces as biofilms such as dust, insects, plants, animals and rocks, rather than suspended in solution. Once a biofilm is developed, other microorganisms are free to attach and benefit from this microbial community. The food industry, which has a rich supply of nutrients, solid surfaces, and raw materials constantly entering and moving through the facility, is an ideal environment for biofilm development, which can potentially protect food pathogens from sanitizers and result in the spread of foodborne illness. Biofilms in the Food Environment is designed to provide researchers in academia, federal research labs, and industry with an understanding of the impact, control, and hurdles of biofilms in the food environment. Key to biofilm control is an understanding of its development. The goal of this 2nd edition is to expand and complement the topics presented in the original book. Readers will find: The first comprehensive review of biofilm development by Campylobacter jejuni An up-date on the resistance of Listeria monocytogenes to sanitizing agents, which continues to be a major concern to the food industry An account of biofilms associated with various food groups such as dairy, meat, vegetables and fruit is of global concern A description of two novel methods to control biofilms in the food environment: bio-nanoparticle technology and bacteriophage Biofilms are not always a problem: sometimes they even desirable. In the human gut they are essential to our survival and provide access to some key nutrients from the food we consume. The authors provide up-date information on the use of biofilms for the production of value-added products via microbial fermentations. Biofilms cannot be ignored when addressing a foodborne outbreak. All the authors for each chapter are experts in their field of research. The Editors hope is that this second edition will provide the bases and understanding for much needed future research in the critical area of Biofilm in Food Environment.
The new 12th edition of Introduction to Genetic Analysis takes this cornerstone textbook to the next level. The hallmark focus on genetic analysis, quantitative problem solving, and experimentation continues in this new edition. The 12th edition also introduces SaplingPlus, the best online resource to teach students the problem solving skills they need to succeed in genetics. SaplingPlus combines Sapling’s acclaimed automatically graded online homework with an extensive suite of engaging multimedia learning resources.
Everything You Need to Know about the Biggest Victory of Women's Rights and Equality in the United States – Written By the Greatest Social Activists, Abolitionists & Suffragists
Everything You Need to Know about the Biggest Victory of Women's Rights and Equality in the United States – Written By the Greatest Social Activists, Abolitionists & Suffragists
Experience the American feminism in its core. Learn about the decades long fight, about the endurance and the strength needed to continue the battle against persistent indifference and injustice. Go back in time and get to know the founders and the followers, the characters of all the strong women involved in the movement. Find out what was the spark which started it all and kept the flame going. Learn about the organization, witness the backdoor conversations and discussions, read their personal correspondence, speeches and planned tactics. Learn about the relationship between great activists and what caused the fraction. See the movement in its full light and learn what it took to obtain most basic civil rights. Know your history! This six volumes edition covers the women's suffrage movement from 1848 to 1922. Originally envisioned as a modest publication that would take only four months to write, it evolved into a work of more than 5700 pages written over a period of 41 years and was completed in 1922, long after the deaths of its visionary authors and editors, Elizabeth Cady Stanton and Susan B. Anthony. However, realizing that the project was unlikely to make a profit, Anthony had already bought the rights from the other authors. As a sole owner, she published the books herself and donated many copies to libraries and people of influence. Elizabeth Cady Stanton (1815–1902) was an American suffragist, social activist, abolitionist, and leading figure of the early women's rights movement. Susan B. Anthony (1820–1906) was an American suffragist, social reformer and women's rights activist. Harriot Stanton Blatch (1856-1940) was a suffragist and daughter of Elizabeth Stanton. Matilda Gage (1826–1898) was a suffragist, a Native American rights activist and an abolitionist. Ida H. Harper (1851–1931) was a prominent figure in the United States women's suffrage movement. She was an American author, journalist and biographer of Susan B. Anthony.
This unique collection of "The Complete History of the Suffragette Movement - All 6 Books in One Edition)" has been designed and formatted to the highest digital standards. Find out what was the spark which started it all and kept the flame going. Learn about the decades long fight, about the endurance and the strength needed to continue the battle against persistent indifference and injustice. Go back in time and get to know the founders and the followers, the characters of all the strong women involved in the movement. Learn about the organization, witness the backdoor conversations and discussions, read their personal correspondence, impressions and planned tactics. Learn about the relationship between great activists and what caused the fraction. See the movement in its full light and learn what it took to obtain most basic civil rights. Know your history! Elizabeth Cady Stanton (1815–1902) was an American suffragist, social activist, abolitionist, and leading figure of the early women's rights movement. Susan B. Anthony (1820–1906) was an American suffragist, social reformer and women's rights activist. Harriot Stanton Blatch (1856-1940) was a suffragist and daughter of Elizabeth Stanton. Matilda Gage (1826–1898) was a suffragist, a Native American rights activist and an abolitionist. Ida H. Harper (1851–1931) was a prominent figure in the United States women's suffrage movement. She was an American author, journalist and biographer of Susan B. Anthony.
Inhaled Pharmaceutical Product Development Perspectives: Challenges and Opportunities describes methods and procedures for consideration when developing inhaled pharmaceuticals, while commenting on product development strategies and their suitability to support regulatory submission. It bridges the gap between the aspirations of scientists invested in new technology development and the requirements that must be met for any new product. The book brings together emerging analytical and inhalation technologies, providing perspectives that illuminate formulation and device design, development, regulatory compliance, and practice. Focusing on underlying scientific and technical principles known to be acceptable from the current regulatory perspective, this monograph will remain useful as a high-level guide to inhaled product development for the foreseeable future. - Discusses development strategies and best practices in the context of regulatory requirements - Written by a broadly qualified expert drawing on the knowledge and critical opinions of key individuals in the field - Includes a foreword by Charles G. Thiel
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