The Civil War claimed over 620,000 lives from April 1861 until the last major battle in June 1865. Neighbor fought neighbor, while families were divided over the issues of states' rights, secession, and slavery. Few people realize that Missouri was the war's third most violent state with over 1,500 battles and skirmishes. Wilson's Creek National Battlefield, southwest of Springfield, commemorates the Battle of Wilson's Creek, which was the first Civil War battle west of the Mississippi River, the second major battle of the war, and where the first Union general was killed in combat. The Wilson's Creek National Battlefield Civil War collection is an outstanding compilation of artifacts, documents, and photographs primarily related to the Trans-Mississippi theater. Items include Arkansas Confederate general Patrick Cleburne's sword belt and sash, abolitionist John Brown's telescope, a Confederate "Cherokee Braves" flag, and an original print of General Order No. 11, which forced evacuation of several western Missouri counties in an attempt to eliminate safe havens for guerrillas.
Springfield, now the third-largest city in the state, was once an area favored by Native Americans for its natural beauty, mild climate, abundant timber, and excellent hunting and fishing. Founded by John Polk Campbell in 1829, the settlement grew steadily, thanks to its civic-minded residents. Springfield's many photographs show these diligent people at work as well as at play. Whether enjoying a vaudeville show at the Landers Theatre in 1891, riding a jitney or streetcar to Doling Park in 1915, or playing in the world's largest Boy Scout Band in 1925, the people of Springfield enjoyed themselves. Images depict businesses such as the Springfield Wagon Company, which became "king" of U.S. wagon manufacturing, and the "Frisco," whose operational hub was housed in Springfield, bringing commercial and industrial diversification. In 1926, the city became the birthplace of the Mother Road, Route 66, which firmly established Springfield's right to the name "Queen City of the Ozarks.
In 1939, Branson was described as "the paradise of the Ozarks--the playground of America." Originally home to the Osage, the harsh rocky terrain made homesteading difficult. The Ozarks's wilderness became a hideout for bushwhackers following the Civil War. The masked "Bald Knobbers" developed as vigilantes to defend mountain families. Today, the "Baldknobbers" are known as Branson's first musical show. In 1894, tours began in Marble Cave, one of 8,000 Ozarks caves. Now known as Marvel Cave, it boasts the largest cave entrance room in the United States and remains a main attraction at Silver Dollar City's theme park. Many visitors are lured by the natural beauty, healthful atmosphere, and recreational activities offered in the Ozarks. Harold Bell Wright penned The Shepherd of the Hills while recuperating here at the beginning of the 20th century. A wave of tourism to the Branson area followed its 1907 publication. Today, the "Live Entertainment Capital of the World" welcomes more than eight million visitors yearly.
The field of non-invasive ventilation continues to expand rapidly since publication of the second edition of Non-Invasive Respiratory Support, new controversies have arisen and numerous practical guidelines have been issued. This expanded third edition with new international contributors has been fully revised and updated. It builds on the success
This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors. Although there have been many symposia on this topic, and numerous publications of reviews dealing with selected subsets of growth factors, the entired field has never been covered in a single treatise. It is essential to do this at the present time, as the number of journal articles on peptide growth factors now makes it almost im anyone person to stay informed on this subject by reading the possible for At the same time it is becoming increasingly apparent that primary literature. these substances are of universal importance in biology and medicine and that the original classification of these molecules, based on the laboratory setting of their discovery, as "growth factors," "lymphokines," "cytokines," or "colony-stimulating factors," was quite artifactual; they are in fact the basis of a common language for intercellular communication. As a set they affect es sentially every cell in the body, and in this regard they provide the basis to develop a unified science of cell biology, germane to all of biomedical research.
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