Biology of Female Cancers explores what can be learned about female cancers by summarizing what is known about the mechanisms of growth regulation and genetic features associated with common forms of female cancers, including malignancies of the breast, ovary, uterus, cervix, vulva, and gestational trophoblastic disease. The book describes the etiology, incidence, pathology, staging, and treatment of each type of cancer. The risk of developing particular tumor types and how their growth may be influenced by hormones, growth factors, and cytokines is also discussed. For oncologists, gynecologists and obstetricians, cell biologists, and everyone interested in learning more about female cancers, the Biology of Female Cancers offers a comprehensive, unique approach.
This book likens writers’ incessant focus on racism, negative ethnicity, patriarchy and social stratification in societies to a naïve physician who prescribes analgesics to treat symptoms while the underlying cause of the disease seethes in the blood. In the same way, persons who consistently blame their reckless conduct and shabbiness miss the point if they do not transform the actual cause of the problem: the mind. While most literary scholars problematise gender disparities, racial and political othering, oppression, environment degradation, education matters, poor parenting and governance, they tend to disregard the root cause: modernism. This book finds a gap in this grey area to address the authentic cause of the symptoms that most literary writers and scholars treat. Pertinent modernist tenets such as bureaucracy, the nation state, systematisation and rationality, and dualism are at the heart of racism, corruption and other aforementioned symptoms. It is the contention of this study that postmodernism offers a comprehensive understanding of modernism to mitigate its effects on society.
Brain damage can cause memory to break down in a number of different ways, the analysis of which can illuminate how the intact brain mediates memory processes. After first considering the problems involved in assessing memory, this book provisionally advances a taxonomy of elementary memory disorders and, for each in turn, reviews both the specific processes that are disrupted and the lesions responsible for the disruption. These disorders include short-term memory deficits, deficits in previously well-established memory, memory decifits caused by frontal lobe lesions, the organic amnesias, the disorders of conditioning and skill acquisition. Particular attention is paid to the organic amnesias, about which we know the most, and to the contributions of animal models to our knowledge. Andrew Mayes argues that the memory deficits found in several neurological and psychiatric syndromes comprise co-occurring elementary memory disorders. Finally, he outlines the implications of his taxonomy for our understanding of normal memory. A wide audience of researchers and students will find Human Organic Memory Disorders a helpful guide to a complex problem area.
Hailed by Margaret Thatcher as the founder of modern conservatism, Keith Joseph is commonly ranked among the most influential politicians of the late-20th century. A complex and enigmatic figure Joseph was almost unique among Mrs Thatcher's senior ministers in refusing to write his own memoirs. Challenging both the "mad monk" view held by his critics and his status of mythical hero to his admirers, the authors present a picture of Joseph as a thinker and decision-maker. the authors tell of Joseph's formative years before he entered Parliamnet in 1956: the powerful Jewish dynasty into which Josph was born; his time at Harrow; at Oxford; his war years in the Royal Artillery; and his Fellowship at All Souls. This volume charts the political career of Keith Joseph. The authors challenge Joseph's self-declared conversion to Conservatism in 1974 and the importance of his "education" of Margaret Thatcher. His own ambition, intellectual integrity and consistency are all examined and a different picture emerges of his role as the intellectual driving force behind Conservative Government policy in the 1980s.
By any measure Arthur Seaforth Blackburn was one of Australia's most remarkable soldiers. This, the first Blackburn biography, details the famous battles that shaped Australia.
This concise and accessible textbook overviews the place and continuing centrality of the concept of class in cultural studies and sociology. The book reopens the debates over class and culture that were very nearly closed down in postmodernism. Andrew Milner offers readers a critical introduction to the Marxist and Weberian accounts of class and relates the significance of class in the new social movements. He also looks at class politics and trends in the character of class relations.
British food has not traditionally been regarded as one of the world's great cuisines, and yet Stilton cheese, Scottish raspberries, Goosnargh duck and Welsh lamb are internationally renowned and celebrated. And then there are all those dishes and recipes that inspire passionate loyalty among the initiated: Whitby lemon buns and banoffi pie, for example; pan haggerty and Henderson's relish. All are as integral a part of the country's landscape as green fields, rolling hills and rocky coastline. In Food Britannia, Andrew Webb travels the country to bring together a treasury of regional dishes, traditional recipes, outstanding ingredients and heroic local producers. He investigates the history of saffron farming in the UK, tastes the first whisky to be produced in Wales for one hundred years, and tracks down the New Forest's foremost expert on wild mushrooms. And along the way, he uncovers some historical surprises about our national cuisine. Did you know, for example, that the method for making clotted cream, that stalwart of the cream tea, was probably introduced from the Middle East? Or that our very own fish and chips may have started life as a Jewish-Portuguese dish? Or that Alfred Bird invented his famous custard powder because his wife couldn't eat eggs? The result is a rich and kaleidoscopic survey of a remarkably vibrant food scene, steeped in history but full of fresh ideas for the future: proof, if proof were needed, that British food has come of age.
Tavistock Press was established as a co-operative venture between the Tavistock Institute and Routledge & Kegan Paul (RKP) in the 1950s to produce a series of major contributions across the social sciences. This volume is part of a 2001 reissue of a selection of those important works which have since gone out of print, or are difficult to locate. Published by Routledge, 112 volumes in total are being brought together under the name The International Behavioural and Social Sciences Library: Classics from the Tavistock Press. Reproduced here in facsimile, this volume was originally published in 1973 and is available individually. The collection is also available in a number of themed mini-sets of between 5 and 13 volumes, or as a complete collection.
Secret Dorchester explores the lesser-known history of the town of Dorchester through a fascinating selection of stories, unusual facts and attractive photographs.
Compiled by acclaimed British military history Andrew Roberts, this is a classic collection of war letters from the frontline revealing the common hopes and fears shared by soldiers across the passage of time. A legacy of an empire and a nation at war, Love Tommy, is a collection of letters housed at the Imperial War Museum sent by British and Commonwealth troops from Canada, Australia, New Zealand and South Africa from the front line of war to their loved ones at home. Poignant expressions of love, hope and fear sit alongside amusing anecdotes, grumbles about rations and thoughtful reflections, eloquently revealing how, despite the passage of time, many experiences of the fighting man are shared in countless wars and battles. From the muddy trenches of the Somme to frozen ground of the Falklands to the heat and dust of Iraq, these letters are the ordinary soldier's testament to life on the front line.
What do Batman, Doctor Who, quantum physics, Oscar Wilde, liberalism, the second law of thermodynamics, Harry Potter fanfic, postmodernism, and Superman have in common? If your answer to that was "Nothing" then... well, you're probably right. But in this book Andrew Hickey will try to convince you otherwise. In doing so he'll take you through: How to escape from a black hole and when you might not want to The scientist who thinks he's proved the existence of heaven and what that has to do with Batman What to do if you discover you're a comic-book character Whether killing your own grandfather is really a bad idea And how to escape from The Life Trap! An examination of the comics of Grant Morrison, Alan Moore and Jack Kirby, Doctor Who spin-off media, and how we tell stories to each other, Sci-Ence! Justice Leak! tells you to look around you and say: "This is an imaginary universe... Aren't they all?
The nearly 200 cases featured in this guide are drawn from the clinical experience of well over 100 clinicians, many of whom are well-known experts in particular areas of diagnosis and treatment.
Taking a practical view with examples from all areas of health, the third edition of this textbook provides a clear, contemporary introduction to epidemiology.
PET imaging has shown its value in diagnosing diseases affecting older people. Most significantly this has been with regard to the diagnosis of Alzheimer's disease and other forms of dementia. Parkinson's disease is another condition in which PET has proved valuable. This issue also included articles on the uses of PET for diagnosing cerebrovascular disease and for assessing neuroplasticity.
This book is an invaluable resource for anyone interested in researching or just learning more about the changing role and status of English across Europe. The status of English today is explained in its historical context before the authors present some of the key debates and ideas relating to the challenge English poses for learners, teachers, and language policy makers.
A steamy whodunnit . . . This may well be the best fiction about the railways since Dickens.' Independent on Sunday 'Genuinely gripping . . . The sort of thing D. H. Lawrence might have written had he been less verbose or been blessed with a sense of humour.' Peter Parker, Evening Standard (Books of the Year) A superbly atmospheric thriller of sabotage, suspicion and steam, The Blackpool Highflyer brings a new twist to tales of Edwardian England and amateur sleuthing. Assigned to drive holidaymakers to the seaside resort of Blackpool in the hot summer of 1905, Jim Stringer is happy to have left behind the grime and danger of life in London. But his dreams of beer and pretty women are soon shattered - when his high-speed train meets a huge millstone on the line . . . 'A clear winner in literary crime writing . . . Dazzling attention to detail and quality writing from one of our best contemporary male novelists.' Daily Express
Since 1927, Goldman-Cecil Medicine has been the world’s most influential internal medicine resource. In the ground-breaking 25th edition, your original purchase ensures you will be up-to-date without the need for a subscription. Through the new, more powerful Expert Consult eBook platform, this "living text" provides continuous updates that will integrate the latest research, guidelines, and treatments into each chapter, ensuring that the content is as current as the day this edition was first published. Goldman-Cecil Medicine offers definitive, unbiased guidance on the evaluation and management of every medical condition, presented by a veritable "Who's Who" of modern medicine. A practical, straightforward style; templated organization; evidence-based references; and robust interactive content combine to make this dynamic resource quite simply the fastest and best place to find all of the authoritative, state-of-the-art clinical answers you need. Expert Consult eBook version included with print purchase: Access continuous updates from Editor Lee Goldman, MD, who thoroughly reviews internal medicine and specialty journals, updating online content to reflect the latest guidelines and translating that evidence into treatment. Interactive Q&A section features over 1,500 board-style questions and answers to aid in preparing for certification or recertification exams. Outstanding supplementary tools include figures, tables, videos, heart and lung sounds, treatment and management algorithms, fully integrated references, and thousands of illustrations and full-color photos. Search all of the text, figures, supplementary material, and references from the book on a variety of devices and at no additional cost — Expert Consult access is included with this title! Practical, bulleted, highly templated text with easy-to-use features including flow charts and treatment boxes. New chapters on global health, cancer biology and genetics, and the human microbiome in health and disease keep you on the cutting edge of medicine. Today's most current evidence-based medicine guidelines help you form a definitive diagnosis and create the best treatment plans possible. Focused coverage of the latest developments in biology includes the specifics of current diagnosis, therapy, and medication doses. The reference of choice for every stage of your career! Goldman-Cecil Medicine is an ideal learning tool for residents, physicians, and students as well as a valuable go-to resource for experienced healthcare professionals.
One hundred and fifty million dollars is a lot of money to giveaway. It is an estimate of how much was paid out in foreign aidlast year. When it helps the sick, the starving, the homeless, the deprived, we feel the money is well spent. But who knows how much is pocketed by greedy gangsters and government officials, in corruption or theft? The origins cannot be traced of eighty percent of hospital drugs in one large country. If you get sick you pay a lot of money for treatment with such drugs, but how they got there, no one seems to know. Those who own the hospitals just get rich. From the south of France to Italy, London to the Russian Far East, Marcus Black searches for someone who knows too much. He finds passion and power, deceit and death. Whether it is Italian omertà or English discretion, so much is kept quiet. And who can be trusted when big money is at stake.
Cognitive neuropsychology seeks to understand impairments of specific cognitive functions in relation to a model of normal cognitive processing. The conclusions drawn from the study of abnormal processes are in turn used in the development and testing of theories of normal cognition. First published in 1988, this seminal book represented an attempt to synthesize and systematize progress in the study of cognitive neuropsychology and therefore provides an important snapshot of the field at the time. In addition to reviewing different forms of impairment and discussing their implications for theories of normal function, this book also examines the empirical and theoretical foundations of the subject including the use of single-case studies and the assumptions that must be made about the mind and brain. This classic edition marks 25 years in print, and includes a brand new introduction written by the authors, Ellis and Young. The Augmented Edition of Human Cognitive Neuropsychology published in 1997 is also still available. This classic edition will be important reading for students of cognitive psychology, cognitive neuroscience and neuropsychology.
The malign and long-lasting influence of Chicago police commander Jon Burge cannot be overestimated, particularly as fresh examples of local and national criminal-justice abuse continue to surface with dismaying frequency. Burge’s decades-long tenure on the Chicago police force was marked by racist and barbaric interrogation methods, including psychological torture, burnings, and mock executions—techniques that went far “beyond the usual beating.” After being exposed in 1989, he became a symbol of police brutality and the unequal treatment of nonwhite people, and the persistent outcry against him led to reforms such as the abolition of the death penalty in Illinois. But Burge hardly developed or operated in a vacuum, as Andrew S. Baer explores to stark effect here. He identifies the darkness of the Burge era as a product of local social forces, arising from a specific milieu beyond the nationwide racialized reactionary fever of the 1960s and 1970s. Similarly, the popular resistance movements that rallied in his wake actually predated Burge’s exposure but cohered with unexpected power due to the galvanizing focus on his crimes and abuses. For more than thirty years, a shifting coalition including torture survivors, their families, civil rights attorneys, and journalists helped to corroborate allegations of violence, free the wrongfully convicted, have Burge fired and incarcerated, and win passage of a municipal reparations package, among other victories. Beyond the Usual Beating reveals that though the Burge scandal underscores the relationship between personal bigotry and structural racism in the criminal justice system, it also shows how ordinary people held perpetrators accountable in the face of intransigent local power.
Though he didn’t play regular first-class cricket until he was 31, Jack Mercer (1893-1987) took nearly 1,500 wickets in the county game, mostly bowling fast-medium for Glamorgan, where he gradually acquired all the variations of that craft. As a batsman he had two principal shots which he named ‘Cautious Caroline’ and ‘Saucy Sally’; the latter brought him a record-setting 31 runs off an eight-ball over in 1939. His involvement with county cricket extended from 1913 when his success with his village side, Southwick, attracted the attention of the Sussex club, through to 1983 when he kept the score book for Northamptonshire seconds. In between he led an astonishingly diverse life. He was in St Petersburg ‘smitten’ with a Russian ballerina when the First War broke out; his aptitude for her language took him to Bletchley Park in the Second. He was watching racing at Longchamps when told he was needed on an MCC tour to India; his white-gloved magician’s hands featured in early television advertisements. Andrew Hignell here relates the life of the one of the most genial and long-serving of county cricket’s practitioners, from the smithy to a Marylebone mews.
Thoroughly revised and updated, this Fourth Edition is the most comprehensive, current reference on lung cancer, with contributions from the world's foremost surgeons, radiation oncologists, medical oncologists, pulmonologists, and basic scientists. Coverage includes complete information on combined modality treatments for small cell and non-small cell lung cancer and on complications of treatment and management of metastases. Emphasis is also given to early detection, screening, prevention, and new imaging techniques. This edition has expanded thoracic oncology chapters including thymus, mesothelioma, and mediastinal tumors, more detailed discussion of targeted agents, and state-of-the-art information on newer techniques in radiotherapy. Other highlights include more international contributors and greater discussion of changes in lung cancer management in each region of the world. A new editor, Giorgio Scagliotti, MD from the University of Turin, has coordinated the accounts of European activities. A companion website includes the full text online and an image bank.
Draws on recent research to address key issues in residential child care policy and practice in the UK, offering guidance for developing best practice and improved outcomes for children and young people.
This book explores the topics of English accents and pronunciation. It highlights their connections with several important issues in the study of English in the world, including intelligibility, identity, and globalization. The unifying strand is provided by English pronunciation models: what do these models consist of, and why? The focus on pronunciation teaching is combined with sociolinguistic perspectives on global English, and the wider question asked by the book is: what does it mean to teach English pronunciation in a globalized world? The book takes Hong Kong – ‘Asia’s World City’ – as a case study of how global and local influences interact, and of how decisions about teaching need to reflect this interaction. It critically examines existing approaches to global English, such as World Englishes and English as a Lingua Franca, and considers their contributions as well as their limitations in the Hong Kong context. A data-based approach with quantitative and qualitative data anchors the discussion and assists in the development of criteria for the contents of pronunciation models. English Pronunciation Models in a Globalized World: Accent, Acceptability and Hong Kong English discusses, among other issues: Global English: A socio-linguistic toolkit Accents and Communication: Intelligibility in global English Teaching English Pronunciation: The models debate Somewhere Between: Accent and pronunciation in Hong Kong Researchers and practitioners of English studies and applied linguistics will find this book an insightful resource.
A legacy of an empire and a nation at war, Letters from the Front is a collection of correspondence sent by British and Commonwealth troops from the front line of war to their loved ones at home. Poignant expressions of love, hope and fear sit alongside amusing anecdotes, grumbles about rations and thoughtful reflections, eloquently revealing how, despite the passage of time, the experiences of the fighting man are shared in countless wars and battles across history. From the muddy trenches of the Somme through the frozen ground of the Falklands to the heat and dust of Afghanistan today, these letters are the ordinary soldier's testament to life on the front line.
Andrew Parker undertakes a critical reconsideration of the frequently absent, or troubled, figure of the mother in theorists including Marx, Freud, Lacan, and Derrida.
The third book in the Cricket Witness series is a celebration of Glamorgan winning the 1948 County Championship. Not only was it their first-ever title, it was achieved just four years after the heartbreak of losing their inspirational captain, Maurice Turnbull, who was killed shortly after the Normandy invasion whilst serving King and Country. Maurice had steered the county through a series of difficult seasons when defeats were more common than success, and the committee was regularly contemplating a return to Minor County status. Elevated into first-class cricket in 1921, Glamorgan CCC were the Cinderella of the county game, with opponents travelling to South Wales only booking two nights’ accommodation instead of the normal three, given the Welsh county’s dreadful form. As defeat followed defeat during their first two decades, Glamorgan’s selection committee often found it difficult to raise a strong team, as talented amateurs declined invitations to play, and, in 1922, they had to draft in a virtually unknown 15-year-old schoolboy for what proved to be his one and only county game. There were calls for the debt-ridden club to wind up but, to the delight of their loyal band of supporters, they continued, and in 1948 Wilf Wooller, the former Welsh rugby international, led the county to the Championship title. This rags-to-riches tale is recounted with the use of contemporary quotes and extracts from the memoirs of the players themselves. It is also lavishly illustrated with many previously unpublished images to celebrate the 70th anniversary of the club’s first Championship-winning season and a special moment in Welsh sporting history.
This book provides a detailed review of state of the art knowledge on critical care topics as well as the latest research findings. It covers the core aspects in excellent detail, but is not so comprehensive as to make its daily use unfeasible. For each condition considered, discussion of the pathophysiology is integrated with observations on diagnosis and treatment in order to allow a deeper understanding. The book is scientifically based, with extensive references to published research. This will allow readers to investigate their individual interests further and will enable physicians to justify measures by providing a coherent, evidence-based strategy and relevant citations where needed. Core Knowledge in Critical Care Medicine will appeal to experienced practitioners as an aide-mémoire, but will also be of great value to a wide range of more junior staff wishing to complement their background knowledge with important facts applicable to everyday practice.
This is a classic edition of Andrew Ellis’ acclaimed introduction to the scientific study of reading, writing and dyslexia, which now includes a new introduction from the author. The book describes the remarkable skills of reading and writing – how we acquire them, how we exercise them as skilled readers and writers, and what can go wrong with them in childhood disorders or as a result of brain damage. The new introduction reflects on some key research developments since the book was first published. Reading, Writing and Dyslexia is an engaging introduction to the field which is still completely relevant to today’s readers. It will remain essential reading for all students of psychology and education, whilst also being accessible to parents and teachers.
Only thirty-nine when he took over the National Gallery in 1955, Jarvis already had an extraordinary record of achievement and social mobility at home and in England: he had trained with Canada's greatest artists, won a Rhodes scholarship, lunched at the Algonquin Round Table in New York, managed an aircraft factory, written a bestseller, produced films, run a slum settlement, and moved in a London social circle that included Noël Coward and Vivien Leigh. As head of the National Gallery, Jarvis was a provocative public educator, advocating his idea of "a museum without walls" in countless public appearances. Instrumental in bringing modern art to the National Gallery, he shook artists and the art-minded public out of a period of national complacency. This first detailed account of the controversy surrounding his time at the gallery provides an important context for the ongoing and contested role of publicly supported arts and art institutions in this country.
This cutting edge text provides insight into the meaning and interpretation of Machiavelli, and highlights the particular relevance to today‘s manager of his works for management, marketing and political thought. It addresses a number of common themes relating to his influences and arguments, and includes topics such as:* modern management* governa
The whole landscape of space use is undergoing a radical transformation. In the workplace a period of unprecedented change has created a mix of responses with one overriding outcome observable worldwide: the rise of distributed space. In the learning environment the social, political, economic and technological changes responsible for this shift have been further compounded by constantly developing theories of learning and teaching, and a wide acceptance of the importance of learning as the core of the community, resulting in the blending of all aspects of learning into one seamless experience. This book attempts to look at all the forces driving the provision and pedagogic performance of the many spaces, real and virtual, that now accommodate the experience of learning and provide pointers towards the creation and design of learning-centred communities. Part 1 looks at the entire learning universe as it now stands, tracks the way in which its constituent parts came to occupy their role, assesses how they have responded to a complex of drivers and gauges their success in dealing with renewed pressures to perform. It shows that what is required is innovation within the spaces and integration between them. Part 2 finds many examples of innovation in evidence across the world – in schools, the higher and further education campus and in business and cultural spaces – but an almost total absence of integration. Part 3 offers a model that redefines the learning landscape in terms of learning outcomes, mapping spatial requirements and activities into a detailed mechanism that will achieve the best outcome at the most appropriate scale. By encouraging stakeholders to creating an events-based rather than space-based identity, the book hopes to point the way to a fully-integrated learning landscape: a learning community.
Research in cognitive psychology has contributed much to our understanding of reading and spelling. Most of this work has concentrated on the processes used by literate adults to comprehend and produce written language, but there is a growing interest in applying cognitive theories to the development of literacy, and to the understanding of disorders of reading and writing. Such disorders may be acquired as a consequence of a brain injury to a previously literate adult, or may be developmental, occurring in otherwise normal children. This textbook attempts to present this work to a non-specialist audience. Though written primarily with students of psychology and education in mind, it is accessible also to parents and teachers. The broad organization of the first edition is retained. The book opens with a consideration of the history and nature of writing, then moves on to deal with the nature of skilled reading. Other chapters deal with: the different ways that brain injury in adulthood can disrupt the mature reading skill the 'acquired dyslexias'; spelling and writing processes, both in skilled writers and in patients with 'acquired dysgraphia'; the way children develop the skills of reading and writing; and developmental reading and writing problems.
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